Sexual reflexes in male and female rats.

abstract：:Age dependent EEG signatures were detected in the EEG of 71 neonates of 28-100 weeks of conceptional age (CA). Using the new method presented, neonates were automatically classified in three age groups (28-35 weeks CA), (36-40 weeks CA) and (41-100 weeks CA). Analysis was performed employing relative distance function...

journal_title：Neuroscience letters

authors： Holthausen K,Breidbach O,Scheidt B,Frenzel J

更新日期：1999-06-25 00:00:00

abstract：:Unilateral transtympanic administration of the sodium channel blocker tetrodotoxin (75 microl of 3 mM TTX in 0.1 M citrate buffer, pH 5.0) produced behavioral symptoms indicative of unilateral vestibular disruption. Following survival times of 2 and 24 h immunocytochemistry for Fos revealed asymmetric labeling in the ...

journal_title：Neuroscience letters

authors： Saxon DW

更新日期：2003-03-13 00:00:00

abstract：:The role of dopamine (DA) in the rat locus coeruleus (LC) was investigated by determining the levels of 3,4-dihydroxyphenylacetic acid (DOPAC), DA and noradrenaline (NA) in the LC after pharmacological treatments by pargyline, haloperidol, 6-hydroxydopamine (6-OHDA) and desmethylimipramine (DMI). The DA, DOPAC and NA ...

journal_title：Neuroscience letters

authors： Milon H,McRae-Degueurce A

更新日期：1982-06-30 00:00:00

abstract：:The roles of the endogenous adenosine on acetylcholine release via adenosine A1 receptor were investigated in rat cerebral cortex using brain microdialysis. Oral administration of KF15372 (8-dicyclopropylmethyl-1,3-dipropylxanthine), a novel selective adenosine A1 receptor antagonist, at doses of 1.25, 5, and 20 mg/kg...

journal_title：Neuroscience letters

authors： Kurokawa M,Shiozaki S,Nonaka H,Kase H,Nakamura J,Kuwana Y

更新日期：1996-05-17 00:00:00

abstract：:Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising cancer drug. One obstacle in TRAIL-based therapies is that many cancer cells, including gliomas, are resistant towards TRAIL. In this study one glioblastoma cell line, one human short-term glioblastoma culture and human astrocytes were tre...

journal_title：Neuroscience letters

authors： Siegelin MD,Siegelin Y,Habel A,Gaiser T

更新日期：2009-04-03 00:00:00

abstract：:This study measured cell proliferation in the hippocampal dentate gyrus in the adult rat at different times within a 12:12h light-dark cycle. The experiments were conducted in animals living in either a complex environment or in standard lab cages. A single dose of the thymidine analog 5-Bromo-2'-deoxyuridine (BrdU) w...

journal_title：Neuroscience letters

authors： Guzman-Marin R,Suntsova N,Bashir T,Szymusiak R,McGinty D

更新日期：2007-07-18 00:00:00

abstract：:GABA transaminase activity is reduced in autopsied putamen samples from patients dying with Huntington's disease. Its activity is also reduced in the striatum of rats previously lesioned with kainic acid. In both cases, the reduction in GABA transaminase activity is comparable with the reduction in glutamate decarboxy...

journal_title：Neuroscience letters

authors： Carter CJ

更新日期：1984-08-10 00:00:00

abstract：:Different responses evoked by stimulation of contralateral hippocampus at various levels are examined in new-born rabbits up to 1 month of age. Commissural fibres coming from the CA3-CA4 reach the contralateral regio superior (CA1) essentially at the st. oriens levels. CA1 responses elicited by stimulation of the cont...

journal_title：Neuroscience letters

authors： Thomson MA

更新日期：1979-02-01 00:00:00

abstract：:Ischemic cerebrovascular diseases, usually involved in hypoxia and reoxygenation, have been reported to increase the risk of dementia such as Alzheimer's disease (AD). beta-site amyloid protein precursor (APP)-cleaving enzymes (BACE1) have been identified to participate in the secretion of beta-amyloid peptides (Abeta...

journal_title：Neuroscience letters

authors： Xue S,Jia L,Jia J

更新日期：2006-09-25 00:00:00

abstract：:Kynurenic acid (KYNA), a neuroactive metabolite of tryptophan that acts on different receptors (e.g. those of N-methyl-D-aspartate (NMDA) and presynaptic α7 nicotinic acetylcholine (nACh)), exerts fundamentally antiglutamatergic effects. In view of its antiglutamatergic properties, an elevation of the KYNA level withi...

journal_title：Neuroscience letters

authors： Demeter I,Nagy K,Farkas T,Kis Z,Kocsis K,Knapp L,Gellert L,Fülöp F,Vecsei L,Toldi J

更新日期：2013-10-11 00:00:00

abstract：:The association of alpha-synuclein (alpha-syn) neuropathology with Parkinson's disease (PD) and several related disorders has led to an intense research effort to develop cerebrospinal fluid (CSF)- or blood-based alpha-syn biomarkers for these types of diseases. Recent studies show that alpha-syn is present in CSF and...

journal_title：Neuroscience letters

authors： Ohrfelt A,Grognet P,Andreasen N,Wallin A,Vanmechelen E,Blennow K,Zetterberg H

更新日期：2009-02-06 00:00:00

abstract：:In the rat, unilateral intrastriatal injection of monoclonal antibodies to acetylcholinesterase (AChE) produced ipsilateral disappearance of AChE-positive nerve terminals within striatum and adjacent cortex. No alterations in striatal staining patterns were observed for tyrosine hydroxylase, somatostatin, neuropeptide...

journal_title：Neuroscience letters

authors： Bean AJ,Xu Z,Chai SY,Brimijoin S,Hökfelt T

更新日期：1991-11-25 00:00:00

abstract：:An event-related decrease in alpha power contralateral to the presentation of a stimulus is now a well-established phenomenon. Two distinct accounts of the functional role of alpha changes are present in the literature that either focus on alpha changes observed during attentional or simple perceptual tasks. This stud...

journal_title：Neuroscience letters

authors： Silas J,Tipple A,Jones A

更新日期：2019-07-13 00:00:00

abstract：:This event-related functional Magnetic Resonance Imaging study examined the differential neural activities associated with a Risky-Gains task in 18 healthy individuals of high (n=9) or low (n=9) impulsiveness, according to their scores on the Barratt Impulsiveness Scale (BIS). The neural activities of people belonging...

journal_title：Neuroscience letters

authors： Lee TM,Chan CC,Han SH,Leung AW,Fox PT,Gao JH

更新日期：2008-06-20 00:00:00

abstract：:This study evaluates the potential neuroprotective properties of amburoside A, a glucoside isolated from Amburana cearensis, on rat mesencephalic cell cultures exposure to the neurotoxin 6-hydroxydopamine (6-OHDA). The parameters determined were cell viability by the 3[4,5-dimethylthiazole-2-il]-2,5-diphenyltetrazoliu...

journal_title：Neuroscience letters

authors： Leal LK,Nobre Júnior HV,Cunha GM,Moraes MO,Pessoa C,Oliveira RA,Silveira ER,Canuto KM,Viana GS

更新日期：2005-11-11 00:00:00

abstract：:The epsilon4 allele of the apolipoprotein E gene (APOE) has repeatedly been associated with increased risk for Alzheimer's disease (AD). Bullido and colleagues recently identified a polymorphism in the promoter region of the APOE gene (-491A/T) and found that -491A homozygosity predicted AD independently of APOE epsil...

journal_title：Neuroscience letters

authors： Town T,Paris D,Fallin D,Duara R,Barker W,Gold M,Crawford F,Mullan M

更新日期：1998-08-14 00:00:00

abstract：:Excitatory amino acid (EAA) receptor-mediated events have recently been implicated in dopaminergic mechanisms of neurotoxicity. 2,4,5-Trihydroxyphenylalanine (6-hydroxy-DOPA, TOPA), the ortho-hydroxylated derivative of the dopamine precursor 2,4-dihydroxyphenylalanine (L-DOPA), has recently been reported to have neuro...

journal_title：Neuroscience letters

authors： Cha JH,Dure LS IV,Sakurai SY,Penney JB,Young AB

更新日期：1991-10-28 00:00:00

abstract：:Total RNA was purified from rat forebrain at different postnatal ages and analyzed by Northern blot using a specific neurotensin receptor RNA probe. The rat neurotensin receptor mRNA was present in high amount during the first 10 days of life. Thereafter, it rapidly decreased and was undetected after 20 days. [3H]neur...

journal_title：Neuroscience letters

authors： Hermans E,Jeanjean AP,Laduron PM,Octave JN,Maloteaux JM

更新日期：1993-07-09 00:00:00

abstract：:Contact heat evoked potentials (CHEPs) have been difficult to elicit due to slow temperature rise times. A recently developed heat-foil technology was used to elicit pain and CHEPs. Two groups of subjects were separately stimulated at the left arm with contact heat via one fast-acting (70 degrees C/s) heat-foil thermo...

journal_title：Neuroscience letters

authors： Chen AC,Niddam DM,Arendt-Nielsen L

更新日期：2001-12-01 00:00:00

abstract：:To investigate the relationship between apolipoprotein E (APOE) polymorphisms and the severity of traumatic brain injury (TBI) in acute stage in the cohort of mainland Chinese patients. We prospectively identified admissions to the two neurosurgical departments for head injury. A total of 110 subjects with TBI (80 mal...

journal_title：Neuroscience letters

authors： Jiang Y,Sun X,Xia Y,Tang W,Cao Y,Gu Y

更新日期：2006-11-13 00:00:00

abstract：:This study tested the hypothesis that cholinoceptive regions of the medial pontine reticular formation (mPRF), long known to play a role in regulating the sleep cycle, can also causally alter the respiratory cycle. In 4 cats, sleep and wakefulness were polygraphically recorded while simultaneous measures were taken of...

journal_title：Neuroscience letters

authors： Lydic R,Baghdoyan HA

更新日期：1989-07-31 00:00:00

abstract：:Neuropathic pain (NP) is one of the most common complications after spinal cord injury (SCI), but no protein biomarkers has ever been introduced into clinical diagnosis. Previous studies implicated that toll-like receptor (TLR) 4 played a critical role in the development of NP in animal SCI models. Here, a total of 14...

journal_title：Neuroscience letters

authors： Xu J,E X,Liu H,Li F,Cao Y,Tian J,Yan J

更新日期：2015-05-19 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH) plays an important role in the regulation of energy balance. While the regulation of TRH in the paraventricular nucleus (PVN) in response to changes of energy balance has been well studied, how TRH is regulated in the dorsomedial hypothalamus (DMH) in maintaining energy homeostasis ...

journal_title：Neuroscience letters

authors： Zhang N,Zhang HY,Bi SA,Moran TH,Bi S

更新日期：2019-06-11 00:00:00

abstract：:The number of neurons in the primary motor cortex (MI) and the primary somatosensory cortex (SI) were estimated in the same locations of brains from sporadic amyotrophic lateral sclerosis (ALS) cases and controls. The number of MI and SI neurons and Betz cells were significantly decreased in the ALS cases as compared ...

journal_title：Neuroscience letters

authors： Mochizuki Y,Mizutani T,Shimizu T,Kawata A

更新日期：2011-09-26 00:00:00

abstract：:Brain edema is among the major complications in children with bacterial meningitis. Aquaporins are integral membrane pore proteins that form channels to regulate cellular water content. Aquaporin-4 (AQP4), which is enriched in parts of astrocytic membranes that are apposed to pial or perivascular basal laminae, is the...

journal_title：Neuroscience letters

authors： Huang J,Lu WT,Sun SQ,Yang ZB,Huang SQ,Gan SW,Xu J,Qiu GP,Zhuo F,Zhu SJ,Jiang J,Jiang XL

更新日期：2014-04-30 00:00:00

abstract：:In situ hybridization of mRNAs for beta- and gamma-cytoplasmic non-muscle actin in the mouse central nervous system revealed their differential expression correlating with the developmental stages. Most intense expression of both isoactin mRNAs at the specific postnatal developmental stage was observed in pyramidal ce...

journal_title：Neuroscience letters

authors： Chiba T,Nakamura Y,Sakiyama S

更新日期：1990-04-20 00:00:00

abstract：:Diabetic polyneuropathy is a common and disturbing complication of diabetes mellitus, presenting patients and caregivers with a substantial disease burden. Emerging mechanisms which are underlying diabetes may provide novel pathways to understand diabetic polyneuropathy (DPN). Specifically, non-coding RNA molecules co...

journal_title：Neuroscience letters

authors： Meydan C,Üçeyler N,Soreq H

更新日期：2020-07-13 00:00:00

abstract：:Rat pineal glands incubated in vitro with 10 or 100 microM norepinephrine (NE) released 51% and 415% more prostaglandin E2 (PGE2) to the medium than in the absence of NE. Phentolamine (10 microM) prevented fully the effect of NE at both concentrations, whereas propranolol failed to affect it significantly. After super...

journal_title：Neuroscience letters

authors： Ritta MN,Cardinali DP

更新日期：1982-08-31 00:00:00

abstract：:The effect of lesions on nerve growth factor receptor (NGFr) immunoreactivity (IR) in motoneurons within the mature feline trigeminal motor nucleus was investigated. Ten days following complete unilateral retrogasserian trigeminal rhizotomy including transection of the trigeminal motor root, motoneurons within the ips...

journal_title：Neuroscience letters

authors： Kullas CD,Henry MA,Westrum LE,Johnson LR,Bothwell M

更新日期：1991-05-27 00:00:00

abstract：:The acute thermoregulatory effect of microinjection of capsaicin into the nucleus raphe dorsalis (NRD) has been studied in anesthetised rats. Application of capsaicin (20 micrograms) into the NRD increased the tail skin temperature and decreased the body temperature. In animals that had previously been treated with ca...

journal_title：Neuroscience letters

authors： Hajós M,Hjorth S,Carlsson A

更新日期：1987-03-31 00:00:00