Genistein enhances proteasomal degradation of the short isoform of FLIP in malignant glioma cells and thereby augments TRAIL-mediated apoptosis.

abstract：:Chemical irritation of the urinary bladder with formalin in the rat induced c-fos protein-like immunoreactivity in more than 80% of substance P receptor-like immunoreactive (SPR-LI) neurons of the dorsal commissural nucleus, sacral parasympathetic nucleus and lamina I in the 6th lumbar and 1st sacral cord segments. Th...

journal_title：Neuroscience letters

authors： Lü Y,Jin SX,Xu TL,Qin BZ,Li JS,Ding YQ,Shigemoto R,Mizuno N

更新日期：1995-09-29 00:00:00

abstract：:Gangliosides isolated from the brain of patients with Creutzfelt-Jakob (C-J) disease were analyzed. The ganglioside current was abnormally low, and the percentage distributions of individual gangliosides and the long-chain base compositions were abnormal. The C20-sphingosine contents of all the ganglioside fractions w...

journal_title：Neuroscience letters

authors： Tamai Y,Ohtani Y,Miura S,Narita Y,Iwata T,Kaiya H,Namba M

更新日期：1979-01-01 00:00:00

abstract：:We investigated the influence of different personality dimensions on neural emotional conflict processing. A cluster analysis separated two different subsamples of subjects. One sample scored high on neuroticism, anxiety, depressivity and low on extraversion and was found to be highly sensitive to emotional conflicts ...

journal_title：Neuroscience letters

authors： Frühholz S,Prinz M,Herrmann M

更新日期：2010-01-22 00:00:00

abstract：:An increase in the arthritis index as a marker of chronic inflammation and suppression of food intake are observed in adjuvant arthritic (AA) rats. Our previous study demonstrated that central oxytocin (OXT)-ergic pathways were activated potently in AA rats. In the present study, OXT-saporin (SAP) cytotoxin, which che...

journal_title：Neuroscience letters

authors： Matsuura T,Kawasaki M,Hashimoto H,Yoshimura M,Motojima Y,Saito R,Ueno H,Maruyama T,Sabanai K,Mori T,Ohnishi H,Sakai A,Ueta Y

更新日期：2016-05-16 00:00:00

abstract：:Capsaicin, a neurotoxin which impairs some primary afferent nerve fibers, was locally applied to the mesenteric nerve trunks of adult guinea pigs. The effect of capsaicin was studied on contractile responses of the ileum to mesenteric nerve stimulation (20 Hz). Exposure of the mesenteric nerve to capsaicin (1 microM) ...

journal_title：Neuroscience letters

authors： Jin JG,Takaki M,Nakayama S

更新日期：1989-11-20 00:00:00

abstract：:In vivo formation of 1-methyl-4-phenylpyridinium ion (MPP(+)) in the striatum, and dopaminergic neurotoxicity following systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the presence and absence of calcium channel agonist (+/-)-Bay K8644 were analyzed in Balb/c mice. We used HPLC-photod...

journal_title：Neuroscience letters

authors： Samantaray S,Mohanakumar KP

更新日期：2003-07-31 00:00:00

abstract：:The input-output relation of a single neuron stands at the basis of every biologically oriented description of the brain. This report shows that the input-output relation of cultured cortical neurons is non-linearly tuned by the input frequency. Increasing the rate of stimulation results in the appearance of ordered t...

journal_title：Neuroscience letters

authors： Tal D,Jacobson E,Lyakhov V,Marom S

更新日期：2001-03-02 00:00:00

abstract：:Several studies demonstrated that the overexpression of miR-124 in neural stem cells (NSCs) could lead the NSCs to differentiate into neurons and astrocytes, which may be important for functional recovery in spinal cord injury. The present study attempted to explore the potential repairing effect of the NSCs transfect...

journal_title：Neuroscience letters

authors： Xu W,Li P,Qin K,Wang X,Jiang X

更新日期：2012-10-31 00:00:00

abstract：:In this study, we investigated the eye movement and postural control performance in dyslexic children while reading text and performing Landolt reading when sitting and standing. Fifteen dyslexic and 15 non-dyslexic children were asked to sit in a chair while the eye movements were recorded, and were then asked to sta...

journal_title：Neuroscience letters

authors： Razuk M,Barela JA,Peyre H,Gerard CL,Bucci MP

更新日期：2018-11-01 00:00:00

abstract：:Microinjection into the dorsolateral pontine tegmentum of the muscarinic agonist bethanechol, leading to activation of cholinoceptive pontine reticular formation (pRF) neurons and the related medullary inhibitory reticulospinal system, did not modify the threshold, latency and amplitude of the forelimb flexion elicite...

journal_title：Neuroscience letters

authors： Luccarini P,Gahery Y,Pompeiano O

更新日期：1990-06-22 00:00:00

abstract：:Neuroinflammation can lead to either damage of astrocytes or astrogliosis. Astrocyte loss may be caused by cytotoxic T cells as seen in Rasmussen encephalitis, auto-antibodies such as in neuromyelitis optica (aquaporin-4 antibodies), or cytokines such as TNF-α in major depressive disorder. Interleukins-1 and -6 appear...

journal_title：Neuroscience letters

authors： Hostenbach S,Cambron M,D'haeseleer M,Kooijman R,De Keyser J

更新日期：2014-04-17 00:00:00

abstract：:Plasminogen belongs to the plasminogen activator system of cell signaling proteins and has recently been identified to bind to pathological prion protein PrPSC, but not to its normal conformer, PrPC. Plasminogen binds specifically to the urokinase-type plasminogen activator receptor (uPAR) to promote pericellular prot...

journal_title：Neuroscience letters

authors： Deininger MH,Trautmann K,Magdolen V,Luther T,Schluesener HJ,Meyermann R

更新日期：2002-05-10 00:00:00

abstract：:Much research is focused on developing novel drugs to improve memory. In particular, psychostimulants have been shown to enhance memory and have a long history of safe use in humans. In prior work, we have shown that very low doses of amphetamine administered before training on a Pavlovian fear-conditioning task can d...

journal_title：Neuroscience letters

authors： Carmack SA,Wood SC,Anagnostaras SG

更新日期：2010-01-01 00:00:00

abstract：:The opioid peptide dynorphin decreased somatic calcium-dependent action potential duration in a portion of mouse dorsal root ganglion (DRG) neurons without altering resting membrane potential or conductance. Dynorphin action was antagonized by naloxone. Responses of DRG neurons to dynorphin differed from responses to ...

journal_title：Neuroscience letters

authors： Werz MA,Macdonald RL

更新日期：1984-05-04 00:00:00

abstract：:The present study aimed at investigating the effects of an artificial head position-based tongue-placed electrotactile biofeedback on postural control during quiet standing under different somatosensory conditions from the support surface. Eight young healthy adults were asked to stand as immobile as possible with the...

journal_title：Neuroscience letters

authors： Vuillerme N,Pinsault N,Chenu O,Demongeot J,Payan Y,Danilov Y

更新日期：2008-02-06 00:00:00

abstract：:Vertical arm pointing movements in two directions (upwards and downwards), imposing two different loads (unload and 0.5 kg) and speeds (normal and fast) have been studied in six subjects. Movements were recorded using an optoelectronic system. Data analysis concentrated upon finger-tip kinematics. Significant effects ...

journal_title：Neuroscience letters

authors： Papaxanthis C,Pozzo T,Stapley P

更新日期：1998-09-04 00:00:00

abstract：:Three forms of stress-induced analgesia (electric shock, forced water-swim and novelty) were used to examine the nature of the endogenous antiopiate system. It was hypothesized that a role of the antiopiate system may be to regulate the extent of antinociception within varying environments. The antiopiate properties o...

journal_title：Neuroscience letters

authors： Galina ZH,Kastin AJ

更新日期：1988-02-03 00:00:00

abstract：:We describe the measurement of beta-nerve growth factor (NGF) content in cerebrospinal fluid (CSF) from multiple sclerosis (MS) patients compared with CSF from age-matched normal subjects using a specific sandwich immunoassay (ELISA). During acute attacks patients exhibit a significant increase of NGF content compared...

journal_title：Neuroscience letters

authors： Laudiero LB,Aloe L,Levi-Montalcini R,Buttinelli C,Schilter D,Gillessen S,Otten U

更新日期：1992-11-23 00:00:00

abstract：:The monoamine innervation of the organum vasculosum lamina terminalis (OVLT) was studied using fluorescence histochemistry and the autoradiographic tracing method. Fluorescence histochemistry demonstrates serotonin terminals in close proximity to the capillary plexus of the OVLT, in the same region where the apparent ...

journal_title：Neuroscience letters

authors： Moore RY

更新日期：1977-08-01 00:00:00

abstract：:Because reelin and prestin genes are located close together on mouse chromosome 5, reelin homozygous mutant mice were compared with littermate controls. Experiments were designed to determine if the deletion in the reeler mouse affects the coding and/or regulatory regions for the expression of prestin, the outer hair ...

journal_title：Neuroscience letters

authors： Zheng J,Richter CP,Cheatham MA

更新日期：2003-08-14 00:00:00

abstract：:To determine whether a trans-synaptic mechanism triggered the effects of reserpine on adrenomedullary mRNAs encoding the norepinephrine transporter and tyrosine hydroxylase, we administered 10 mg/kg reserpine to rats after unilateral splanchnicotomy, and examined their adrenal medullas using quantitative in situ hybri...

journal_title：Neuroscience letters

authors： Cubells JF,Baker H,Volpe BT,Smith GP,Das SS,Joh TH

更新日期：1995-07-07 00:00:00

abstract：:The fine structure of striato-nigral efferent neurons, retrogradely labeled with HRP, was studied. The neuron showed a medium sized ovoid or tri-angular perikaryon. Short or medium lengthened granular endoplasmic reticula, having a tendency to wind and pile up in stacks were observed. This neurons corresponds to a typ...

journal_title：Neuroscience letters

authors： Kaiya H,Okinaga M,Namba M,Shoumura K,Watanabe S

更新日期：1979-09-01 00:00:00

abstract：:Free radical generation and release from the cerebral hemispheres of rats subjected to four-vessel occlusion elicited cerebral ischemia/reperfusion was monitored using a cortical cup technique with the spin-trapping agent alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone (POBN). Electron spin resonance (ESR) was used to d...

journal_title：Neuroscience letters

authors： Phillis JW,Sen S,Cao X

更新日期：1994-03-14 00:00:00

abstract：:We investigated glutamate-induced neuron response in the ventral nerve cord of the earthworm (Eisenia foetida) using a voltage-sensitive dye-imaging technique. Isolated earthworm ganglia were stained by fluorescence voltage-sensitive dye, RH414, and voltage image was acquired by a conventional charge-coupled device (C...

journal_title：Neuroscience letters

authors： Oka K,Ogawa H,Fujita S

更新日期：1994-09-26 00:00:00

abstract：:A tight coupling between lexico-semantic access and motor control has been established on the basis of neuropsychological, neurophysiological, and behavioral evidence. For example, sensory and motor cortices have been shown to be active when subjects listen to words denoting bodily actions. Kinematic analyses of subje...

journal_title：Neuroscience letters

authors： Shiller DM,Bourguignon N,Frak V,Nazir T,Cadoret G,Robert M,Lemay M

更新日期：2013-10-25 00:00:00

abstract：:Nociceptin/orphanin FQ (NC) and its receptor (OP(4)) have been implicated in the regulation of various functions including nociception. [Nphe(1)]NC(1-13)NH(2) (Nphe) is a selective OP(4) antagonist which prevents the pronociceptive effects of supraspinal NC and causes per se a naloxone-insensitive antinociceptive effe...

journal_title：Neuroscience letters

authors： Di Giannuario A,Rizzi A,Pieretti S,Guerrini R,Bertorelli R,Salvadori S,Regoli D,Calo G

更新日期：2001-12-04 00:00:00

abstract：:Previous studies on the effects of serotonin receptor 1A (5-HT1A) gene variation on treatment response in depression revealed inconsistent results with studies pointing towards a detrimental influence of the 5-HT1A-1019G allele on antidepressant treatment response, while others did not discern any involvement of 5-HT1...

journal_title：Neuroscience letters

authors： Baune BT,Hohoff C,Roehrs T,Deckert J,Arolt V,Domschke K

更新日期：2008-05-09 00:00:00

abstract：:A large dose of carbachol (5 micrograms/0.5 microliters) unilaterally microinjected into the rostral substantia nigra of rats induced stereotypy characterized by biting, gnawing and licking. A lower dose (0.5 micrograms/0.5 microliter) of the cholinomimetic potentiated normal food intake in satiated animals. Both the ...

journal_title：Neuroscience letters

authors： Taha EB,Redgrave P

更新日期：1980-12-01 00:00:00

abstract：:Topographical maps form the basis of the organization in many projections within the central nervous system, but in the neuromuscular system such detailed spatial organization has generally been assumed to be absent and indeed unnecessary for normal function (see, for example, ref. 1). However, there is some physiolog...

journal_title：Neuroscience letters

authors： Hardman VJ,Brown MC

更新日期：1985-10-10 00:00:00

abstract：:Parkinson's disease (PD) is a common neurodegenerative disease characterized pathologically by the selective loss of dopaminergic neurons in the substantia nigra and the intracellular accumulation of α-synuclein in the Lewy bodies. While the pathogenic mechanisms of PD are poorly understood, many lines of evidence poi...

journal_title：Neuroscience letters

authors： Sheehan P,Yue Z

更新日期：2019-04-01 00:00:00