Expression of c-fos protein in substance P receptor-like immunoreactive neurons in response to noxious stimuli on the urinary bladder: an observation in the lumbosacral cord segments of the rat.

abstract：:This study explored whether patients with Parkinson's disease alter the regulation of upright standing according to constraints imposed by the environmental context. The provision of context-dependent adaptations was inferred from the presence of adjustments to standing postural control that would serve to reduce fall...

journal_title：Neuroscience letters

authors： Brown LA,Doan JB,Whishaw IQ,Suchowersky O

更新日期：2007-05-18 00:00:00

abstract：:The stability of neurotensin (NT) and a potent, long lasting analogue, [D-Trp11]-NT, to rat brain peptidases was compared by incubating the peptides with subcellular fractions (synaptosomes, synaptic membranes) and a purified endopeptidase from rat brain. Degradation of the peptides with time was followed by high perf...

journal_title：Neuroscience letters

authors： McDermott JR,Gibson AM,Biggins JA

更新日期：1986-12-03 00:00:00

abstract：:Both muscarinic and nicotinic acetylcholine (ACh) receptors are known to be present on the surface of lymphocytes. We have shown that variable amounts of ACh are detectable in the blood of various mammals including humans, and a major portion of blood ACh is localized in circulating mononuclear leukocytes in humans. I...

journal_title：Neuroscience letters

authors： Fujii T,Tajima S,Yamada S,Watanabe Y,Sato KZ,Matsui M,Misawa H,Kasahara T,Kawashima K

更新日期：1999-01-08 00:00:00

abstract：:The present work describes the formation of a transient efferent axonal projection from the isthmo-optic nucleus (ION) to the ipsilateral optic tectum of the chick embryo. Local application of either the carbocyanine dye DiI or rhodamine-B-isothiocyanate (RITC) to the superficial layers of the optic tectum resulted in...

journal_title：Neuroscience letters

authors： Wizenmann A,Thanos S

更新日期：1990-06-08 00:00:00

abstract：:To investigate potential trophic actions of extracellular ATP in human astrocytes, we have examined mitogenic signaling by purinergic receptors in cultures prepared from first trimester rostral central nervous system tissue. We found that ATP and ATPgammaS, a hydrolysis-resistant analog, stimulated DNA synthesis, ther...

journal_title：Neuroscience letters

authors： Neary JT,McCarthy M,Kang Y,Zuniga S

更新日期：1998-02-20 00:00:00

abstract：:Neurotrophic factors may be used to improve the growth and repair of injured peripheral nerves. In this study we determined the effectiveness of recombinant human growth hormone on peripheral nerve injury in the Wistar rat. The ulnar nerve of the rat was sectioned and its proximal and distal ends were sutured to eithe...

journal_title：Neuroscience letters

authors： Saceda J,Isla A,Santiago S,Morales C,Odene C,Hernández B,Deniz K

更新日期：2011-10-24 00:00:00

abstract：:Day-night variations of gastrin releasing peptide (GRP) in the neuronal somal area of the SCN and the nearby region on the anterior hypothalamic area (AHA) where GRP fibers project, were examined by semiquantitative immunocytochemistry, and compared with those of vasoactive intestinal peptide (VIP). Both in the SCN an...

journal_title：Neuroscience letters

authors： Okamura H,Ibata Y

更新日期：1994-11-07 00:00:00

abstract：:Xenopus oocytes were coinjected with cDNAs encoding the Drosophila melanogaster metabotropic glutamate receptor (DmGluRA) and two mammalian G-protein inwardly rectifying potassium channel subunits (GIRK1 and GIRK2). Glutamate and two vertebrate group II mGluR agonists (order of potency: LY 354740 > glutamate > DCG IV)...

journal_title：Neuroscience letters

authors： Raymond V,Hamon A,Grau Y,Lapied B

更新日期：1999-07-02 00:00:00

abstract：:Anterior pharynx-defective 1 (Aph-1) is a multi-spanning membrane protein and an integral component of the high molecular weight gamma-secretase complex that also contains presenilin, nicastrin, and Pen-2. In order to clarify the existence of an endogenous fragment of Aph-1 and dissect the localization and processing ...

journal_title：Neuroscience letters

authors： Sanjo N,Katayama T,Hasegawa H,Jin H,Duthie M,Mount HT,Mizusawa H,St George-Hyslop P,Fraser PE

更新日期：2010-10-08 00:00:00

abstract：:Recent evidence suggests a predominant role for potassium (K) efflux in apoptotic cell death yet there exists controversy as to the exact nature of this involvement of K. In the present study we tested the anti-apoptotic efficacy of K channel blockers, tetraethylammonium Cl (TEA), and high extracellular K, the sodium ...

journal_title：Neuroscience letters

authors： Small DL,Tauskela J,Xia Z

更新日期：2002-12-13 00:00:00

abstract：:The effects of nifedipine, niguldipine, nimodipine and nitrendipine on the high K+-induced intracellular Ca2+ ([Ca2+]i) transient in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid NG 108-15 cells were studied by using the fluorescent Ca2+ indicator fura-2. It was observed that nifedipine at the concentrat...

journal_title：Neuroscience letters

authors： Li SN,Bräter M,Andreas K

更新日期：1997-07-18 00:00:00

abstract：:The role of intracellular amyloid beta (iAbeta) in Alzheimer's disease (AD) initiation and progression attracts more and more attention in recent years. To address whether iAbeta induces early alterations of electrophysiological properties in cultured human primary neurons, we delivered iAbeta with adeno-virus and mea...

journal_title：Neuroscience letters

authors： Hou JF,Cui J,Yu LC,Zhang Y

更新日期：2009-10-25 00:00:00

abstract：:The transcription factors AP-2alpha and AP-2beta are implicated to play an important role during embryonic development of different parts of the brain, and in targeted regulation of gene expression in the adult brain. Several monoaminergic genes have binding sites for AP-2 in regulatory regions. We have in the present...

journal_title：Neuroscience letters

authors： Damberg M,Eller M,Tõnissaar M,Oreland L,Harro J

更新日期：2001-11-02 00:00:00

abstract：:Effects of near-ultraviolet (UV-A; 325-390 nm, peak at 365 nm) light on the activity of the pineal serotonin N-acetyltransferase (NAT; a penultimate and key regulatory enzyme in melatonin biosynthesis) were examined in rats. Acute exposure of dark-adapted animals to UV-A radiation produced a marked suppression of NAT ...

journal_title：Neuroscience letters

authors： Zawilska JB,Rosiak J,Nowak JZ

更新日期：1998-02-27 00:00:00

abstract：:Bilateral complete transection of the fimbria-fornix causes a significant increase in nerve growth factor (NGF) content both in the septum and hippocampus of the adult rat as measured by a sensitive immunoassay 7 days after lesioning. The finding, that elevation of NGF in septum (250%) was much more pronounced than th...

journal_title：Neuroscience letters

authors： Weskamp G,Gasser UE,Dravid AR,Otten U

更新日期：1986-09-25 00:00:00

abstract：:The effect of dopamine on the 3',5'-cyclic adenosine monophosphate (cAMP) generating system of membrane particles of rat prostate gland was studied. Dopamine increased the concentration of cAMP in a dose-dependent manner. The selective D1 receptor inhibitor SCH 23390 caused a decrease in dopamine-elicited cAMP levels....

journal_title：Neuroscience letters

authors： Amenta D,Cavallotti C,Amenta F

更新日期：1987-06-01 00:00:00

abstract：:The aim of the study was to evaluate the role of steady-state and dynamic visual gestures of vowels in stuttering inhibition. Eight adults who stuttered recited sentences from memory while watching video presentations of the following visual speech gestures: (a) a steady-state /u/, (b) dynamic production of /a-i-u/, (...

journal_title：Neuroscience letters

authors： Guntupalli VK,Nanjundeswaran C,Kalinowski J,Dayalu VN

更新日期：2011-03-29 00:00:00

abstract：:Spasticity in chronic hemiparetic stroke patients has primarily been treated pharmacologically. However, there is increasing evidence that physical rehabilitation can help manage hyper-excitability of reflexes (hyperreflexia), which is a primary contributor to spasticity. In the present study, one chronic hemiparetic ...

journal_title：Neuroscience letters

authors： Hoseini N,Koceja DM,Riley ZA

更新日期：2011-10-24 00:00:00

abstract：:The aim of the present study is to investigate the mechanisms of suppression of splenic natural killer (NK) cytotoxicity caused by cold stress, using 6-hydroxydopamine (6-OHDA) as chemical sympathectomy. The NK activity was measured by (51)chromium release assay. Central sympathectomy with intracerebroventricular inje...

journal_title：Neuroscience letters

authors： Jiang XH,Guo SY,Xu S,Yin QZ,Ohshita Y,Naitoh M,Horibe Y,Hisamitsu T

更新日期：2004-03-18 00:00:00

abstract：:Recent studies suggest that mild hypothermia significantly alleviate damage following cerebral ischemia though the precise mechanism is poorly defined. In the present study, middle cerebral artery occlusion (MCAo) was induced in Sprague-Dawley (SD) rats for 1 h followed by varying periods of reperfusion. Cerebral infa...

journal_title：Neuroscience letters

authors： Prakasa Babu P,Yoshida Y,Su M,Segura M,Kawamura S,Yasui N

更新日期：2000-09-22 00:00:00

abstract：:Three populations of opiate binding sites (mu, delta and kappa) could be distinguished by displacement studies with the mu-agonist (D)-Ala2-MePhe4-Glyol5-enkephalin and the kappa-agonist [3H](-)-bremazocine in brain membranes of different species. Whereas brain membranes from pig or guinea-pig and human cortical membr...

journal_title：Neuroscience letters

authors： Maurer R

更新日期：1982-06-30 00:00:00

abstract：:The contribution of angiotensin II (Ang II) to the pathophysiology of hypertension is established based on facts that high levels of circulating Ang II increase vasoconstriction of peripheral arteries causing a rise in blood pressure (BP). In addition, circulating Ang II has various effects on the central nervous syst...

journal_title：Neuroscience letters

authors： Issa AT,Miyata K,Heng V,Mitchell KD,Derbenev AV

更新日期：2012-06-21 00:00:00

abstract：:The FE65 protein was previously described interacting with amyloid protein precursor (APP) and mediating its internalization. Hu et al. (Hum. Genet., 103 (1998) 295) recently reported that a deletion polymorphism in intron 13 of the FE65 gene may be protective for sporadic Alzheimer's disease (AD) forms and suggested ...

journal_title：Neuroscience letters

authors： Lambert JC,Mann D,Goumidi L,Harris J,Pasquier F,Frigard B,Cottel D,Lendon C,Iwatsubo T,Amouyel P,Chartier-Harlin MC

更新日期：2000-10-20 00:00:00

abstract：:Parkinson's disease (PD) is the second most frequent neurodegenerative disorder. It is characterized by selective degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). Early-onset familial forms of PD are associated with mutations in several genes, including parkin, pink1 and dj-1. DJ-1 en...

journal_title：Neuroscience letters

authors： Jaramillo-Gómez J,Niño A,Arboleda H,Arboleda G

更新日期：2015-08-31 00:00:00

abstract：:Following the i.c.v. administration of antivasopressin serum the alpha-MPT-induced disappearance of noradrenaline was decreased in the dorsal septal nucleus, parafascicular nucleus and the rostral part of the nucleus tractus solitarii, whereas that of dopamine was lowered in the caudate nucleus and in the A2 region of...

journal_title：Neuroscience letters

authors： Versteeg DH,De Kloet ER,Greidanus TV,De Wied D

更新日期：1979-01-01 00:00:00

abstract：:Previous studies from our team have shown that a 12 month ethanol administration induced deficits in a sequential alternation task, whereas a 6 month treatment had no effects. We have already shown that the 12 month treatment induced deficits both in diencephalic and hippocampal structures, whereas the 6 month treatme...

journal_title：Neuroscience letters

authors： Beracochea D,Jaffard R

更新日期：1991-12-16 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is a major regulator of angiogenesis and blood vessel function. Recent evidence indicates that VEGF facilitates memory and learning through stimulating angiogenesis and neurogenesis in the rat hippocampal dendate gyrus. Abnormal regulation of VEGF expression has been reported ...

journal_title：Neuroscience letters

authors： Mateo I,Llorca J,Infante J,Rodríguez-Rodríguez E,Sánchez-Quintana C,Sánchez-Juan P,Berciano J,Combarros O

更新日期：2006-06-19 00:00:00

abstract：:We have looked at the effect of synthetic mu-conotoxin GIIIA, a selective blocker of muscle Na channels, on various parameters of synaptic transmission at the frog sartorius nerve-muscle preparation. We found that 5 microM mu-conotoxin consistently blocked muscle action potentials, but had no effect on nerve action po...

journal_title：Neuroscience letters

authors： Sosa MA,Zengel JE

更新日期：1993-07-23 00:00:00

abstract：:Reactive oxygen species (ROS) are implicated in the pathogenesis of multiple sclerosis (MS) and its murine model experimental autoimmune encephalomyelitis (EAE). The effect of edaravone, a free radical scavenger, on EAE was investigated in this study. Treatment with edaravone significantly ameliorated the clinical sev...

journal_title：Neuroscience letters

authors： Moriya M,Nakatsuji Y,Miyamoto K,Okuno T,Kinoshita M,Kumanogoh A,Kusunoki S,Sakoda S

更新日期：2008-08-08 00:00:00

abstract：:During neuromuscular development, the nerve induces the expression of acetylcholine receptor (AChR) epsilon-subunit gene selectively in synaptic myonuclei. Here we show that even after elimination of neural effects by denervation, synaptic expression of epsilon-subunit transcripts is maintained for > 4 months. In cont...

journal_title：Neuroscience letters

authors： Herczeg A,Jones G,Brenner HR

更新日期：1995-06-23 00:00:00