Ultrastructure of acetylcholinesterase containing striato-nigral neurons transporting HRP retrogradely.

abstract：:Electroencephalogram (EEG) data is an effective indicator to evaluate driver fatigue. The 16 channels of EEG data are collected and transformed into three bands (θ, α, and β) in the current paper. First, 12 types of energy parameters are computed based on the EEG data. Then, Grey Relational Analysis (GRA) is introduce...

journal_title：Neuroscience letters

authors： Li W,He QC,Fan XM,Fei ZM

更新日期：2012-01-11 00:00:00

abstract：:We had previously reported that small gap neurorrhaphy by scissoring and sleeve-jointing epineurium could enhance the rate and quality of peripheral nerve regeneration. To date, local implantation and systemic delivery of bone marrow mesenchymal stem cells (BMSCs) have been routinely used in nerve tissue engineering, ...

journal_title：Neuroscience letters

authors： Wang P,Zhang Y,Zhao J,Jiang B

更新日期：2015-01-12 00:00:00

abstract：:Pitrazepin is a potent new GABA antagonist which differs from bicuculline in its chemical structure and its interaction with both [3H]muscimol and [3H]flunitrazepam binding sites, whereby the potency of pitrazepin in displacing [3H]muscimol exceeds that of bicuculline by at least a factor of 10. In physiological exper...

journal_title：Neuroscience letters

authors： Gähwiler BH,Maurer R,Wüthrich HJ

更新日期：1984-04-06 00:00:00

abstract：:The influence of testosterone on the postnatal development of reflex electromyographic (EMG) jaw muscle activity evoked by injection of mustard oil (MO) into the temporomandibular joint region and the later recurrence of this EMG activity after intravenous injection of naloxone, was studied in male rats. MO-evoked EMG...

journal_title：Neuroscience letters

authors： Seo K,Fujiwara N,Cairns BE,Someya G

更新日期：2002-12-25 00:00:00

abstract：:It has been known that ethanol causes neuronal cell death through oxidative stress. Ethanol itself and reactive oxygen species (ROS) produced by ethanol modulate intracellular signaling pathways including mitogen-activated protein kinase (MAPK) cascades. This study was conducted to examine the impact of ethanol on MAP...

journal_title：Neuroscience letters

authors： Ku BM,Lee YK,Jeong JY,Mun J,Han JY,Roh GS,Kim HJ,Cho GJ,Choi WS,Yi GS,Kang SS

更新日期：2007-05-23 00:00:00

abstract：:The effects of various Flustra foliacea metabolites on different types of human neuronal nicotinic acetylcholine receptors (nAChRs) expressed in Xenopus oocytes were investigated. Whereas most of the compounds tested had a small blocking effect, one of them, deformylflustrabromine, selectively increased the current ob...

journal_title：Neuroscience letters

authors： Sala F,Mulet J,Reddy KP,Bernal JA,Wikman P,Valor LM,Peters L,König GM,Criado M,Sala S

更新日期：2005-01-10 00:00:00

abstract：:Alzheimer's disease has become one of the most impacting disorders since world population is rapidly aging. MicroRNA-125b plays a crucial role in many cellular processes and pathologies, but, to date, its role in Alzheimer's disease is controversial. In this study, we demonstrated, for the first time, that the down re...

journal_title：Neuroscience letters

authors： Micheli F,Palermo R,Talora C,Ferretti E,Vacca A,Napolitano M

更新日期：2016-08-26 00:00:00

abstract：:Nitric oxide, an endogenous gas produced by nitric oxide synthase (NOS), has been described as a neuromodulator of hormone secretion, including the neurohypophysial peptides oxytocin (OT) and vasopressin (AVP), hormones involved in the sodium and water homeostasis. The presence of NOS in the hypothalamic nuclei as wel...

journal_title：Neuroscience letters

authors： Ventura RR,Giusti-Paiva A,Gomes DA,Elias LL,Antunes-Rodrigues J

更新日期：2005-05-06 00:00:00

abstract：:Morphological changes induced by 30 min of hypoxia (incubation in medium saturated with 95% N2-5% CO2 instead of the normal 95% O2-5% CO2) were investigated in neurons (layers II/III of the parietal cortex) of rat neocortical brain slices. The cells were identified as intact, reversibly or irreversibly injured. As exp...

journal_title：Neuroscience letters

authors： Garcia de Arriba S,Franke H,Pissarek M,Nieber K,Illes P

更新日期：1999-09-24 00:00:00

abstract：:Which cognitive processes are reflected by the N400 in ERPs is still controversial. Various recent articles (Lau et al., 2008; Brouwer et al., 2012) have revived the idea that only lexical pre-activation processes (such as automatic spreading activation, ASA) are strongly supported, while post-lexical integrative proc...

journal_title：Neuroscience letters

authors： Steinhauer K,Royle P,Drury JE,Fromont LA

更新日期：2017-06-09 00:00:00

abstract：:The electrophysiological mechanism underlying afterhyperpolarization induced by the activation of the nicotinic acetylcholine receptor (nAChR) in male rat major pelvic ganglion neurons (MPG) was investigated using a gramicidin-perforated patch clamp and microscopic fluorescence measurement system. Acetylcholine (ACh) ...

journal_title：Neuroscience letters

authors： Park KS,Cha SK,Kim MJ,Kim NH,Lee JW,Jeong SW,Kong ID

更新日期：2010-09-27 00:00:00

abstract：:Calcium antagonists inhibit both the Ca2(+)-dependent and -independent release of endogenous glutamate from intact synaptosomes. In the present study, the inhibitory potency of several different classes of calcium antagonists were determined under conditions that control for an effect of these compounds on the Ca2(+)-...

journal_title：Neuroscience letters

authors： Terrian DM,Dorman RV,Gannon RL

更新日期：1990-11-13 00:00:00

abstract：:The present investigation describes for the first time leg lateral abduction performance during long-term microgravity exposure. Two astronauts took part in the experiments, starting 2 weeks into the mission and lasting for 5 months. Results on joint angles kinematics confirm previous investigations on parabolic fligh...

journal_title：Neuroscience letters

authors： Pedrocchi A,Baroni G,Mouchnino L,Ferrigno G,Pedotti A,Massion J

更新日期：2002-02-22 00:00:00

abstract：:In situ hybridization of mRNAs for beta- and gamma-cytoplasmic non-muscle actin in the mouse central nervous system revealed their differential expression correlating with the developmental stages. Most intense expression of both isoactin mRNAs at the specific postnatal developmental stage was observed in pyramidal ce...

journal_title：Neuroscience letters

authors： Chiba T,Nakamura Y,Sakiyama S

更新日期：1990-04-20 00:00:00

abstract：:In this study, we investigated two newly reported polymorphisms in association with late onset Alzheimer's disease (AD) in Chinese. They were a -491 A/T polymorphism in the Apolipoprotein E (APOE) promoter region and a five base pair deletion at exon 18 of alpha2-Macroglobin (A2M). There were 196 AD and 180 normal con...

journal_title：Neuroscience letters

authors： Chen L,Baum L,Ng HK,Chan LY,Sastre I,Artíga MJ,Valdivieso F,Bullido MJ,Chiu HF,Pang CP

更新日期：1999-07-16 00:00:00

abstract：:The distribution and origin of axon terminals containing nitric oxide synthase (NOS) were examined in the nucleus of the solitary tract (NST) of the rat by NADPH diaphorase histochemistry combined with nodose ganglionectomy. Axon terminals with NADPH diaphorase activity were densely distributed in the middle and cauda...

journal_title：Neuroscience letters

authors： Lü Y,Ding YQ,Qin BZ,Li JS

更新日期：1994-04-25 00:00:00

abstract：:The ubiquitin carboxy-terminal hydrolase L1gene (UCH-L1) has been implicated in the aetiology of Parkinson's disease (PD). A rare Ile93Met mutation in UCH-L1 in a German PD sib-pair has been reported. Recently, a S18Y (C54A) polymorphism in exon 3 of UCH-L1 was found to be under-represented in PD patients compared to ...

journal_title：Neuroscience letters

authors： Mellick GD,Silburn PA

更新日期：2000-10-27 00:00:00

abstract：:Reduced supply of glucose involves in many pathological conditions such as stroke and contributes to ischemic injuries. In contrast, hyperglycemia has also been regarded as an important factor in causing and exaggerating stroke damage. Although the molecular mechanism(s) of imbalanced glucose-induced cellular injuries...

journal_title：Neuroscience letters

authors： Shi H,Liu KJ

更新日期：2006-12-13 00:00:00

abstract：:It has been shown that orexin neuropeptides contribute to morphine-induced physical dependence. The locus coeruleus (LC), which receives a dense extra-hypothalamic orexinergic projection, is a key brain region implicated in the expression of somatic signs of morphine withdrawal syndrome. The aim of the present study i...

journal_title：Neuroscience letters

authors： Azizi H,Mirnajafi-Zadeh J,Rohampour K,Semnanian S

更新日期：2010-10-04 00:00:00

abstract：:The effect of antagonists on N-methyl-D-aspartate (NMDA)-induced response was investigated in isolated nucleus tractus solitarii (NTS) neurons freshly isolated from the rat using a conventional pathclamp technique. The NMDA-induced inward current consisted of an initial peak followed by a steady-state component. The c...

journal_title：Neuroscience letters

authors： Nakagawa T,Shirasaki T,Tateishi N,Murase K,Akaike N

更新日期：1990-05-31 00:00:00

abstract：:The association between insulin degrading enzyme (IDE) gene polymorphisms and Alzheimer's disease (AD) risk has been widely reported, but results were somewhat controversial. To assess the association between IDE polymorphisms and AD risk, a meta-analysis was performed. We systematically reviewed relevant studies retr...

journal_title：Neuroscience letters

authors： Zhang Y,Wang B,Wan H,Zhou Q,Li T

更新日期：2013-04-29 00:00:00

abstract：:The ganglion cell density of the quail's retina was studied in sections and whole mounts. Two regions of high ganglion cell density were found, corresponding to an afoveate area centralis and an area dorsalis. Oil droplets were found to be isotropically distributed throughout the retina. It is proposed that the signif...

journal_title：Neuroscience letters

authors： Budnik V,Mpodozis J,Varela FJ,Maturana HR

更新日期：1984-09-28 00:00:00

abstract：:Vascular cognitive impairment (VCI) is the second most common cause of dementia after Alzheimer's disease, and the cognitive impairment is one of the common effects of VCI. Unfortunately, it lacks effective therapeutic treatments at present. In our previous study, environmental enrichment (EE), as an early interventio...

journal_title：Neuroscience letters

authors： Xu L,Qu C,Qu C,Shen J,Song H,Li Y,Li T,Zheng J,Zhang J

更新日期：2020-11-20 00:00:00

abstract：:Resting-state functional magnetic resonance imaging has confirmed that the strengths of the long distance functional connectivity between different brain areas are correlated with individual differences in intelligence. However, the association between the local connectivity within a specific brain region and intellig...

journal_title：Neuroscience letters

authors： Wang L,Song M,Jiang T,Zhang Y,Yu C

更新日期：2011-01-25 00:00:00

abstract：:We investigated the relation between visual feedback and the degree of structure versus randomness in the variability of single-digit, isometric force output. Participants were instructed to maintain a constant level of force during the presence or absence of visual feedback about force output. The structure of force ...

journal_title：Neuroscience letters

authors： Athreya DN,Van Orden G,Riley MA

更新日期：2012-03-28 00:00:00

abstract：:Bath-applied N-methyl-D,L-aspartate (NMA) was found to elicit locomotor electromyogram (EMG) activity in ankle flexor and extensor muscles in an in vitro lumbar cord-hindlimb preparation of the newborn rat. The frequency and burst duration of the NMA-induced rhythmic EMG activity varied in a dose-dependent manner. The...

journal_title：Neuroscience letters

authors： Kudo N,Yamada T

更新日期：1987-03-20 00:00:00

abstract：:Stimulation of murine primary microglia with Toll-like receptor (TLR) agonists enhances their ability to phagocytose and kill bacteria. Here we show that the viral TLR3 agonist poly(I:C) stimulates the release of cyto-/chemokines and nitric oxide by microglia. Poly(I:C) increases microglial phagocytosis and intracellu...

journal_title：Neuroscience letters

authors： Ribes S,Adam N,Ebert S,Regen T,Bunkowski S,Hanisch UK,Nau R

更新日期：2010-09-20 00:00:00

abstract：:Horseradish peroxidase (HRP) was injected into the thalamic ventral tier of squirrel monkey and the brainstem was examined for the presence of HRP-reactive cells in the external cuneate nucleus (ECN), nuclei Z and X, and the mesencephalic nucleus of the trigeminal nerve (MNV). Results indicate that the ECN, Z and X ha...

journal_title：Neuroscience letters

authors： Pearson JC,Garfunkel DA

更新日期：1983-10-31 00:00:00

abstract：:Rats with suprachiasmatic nuclei (SCN) lesions did not show increased sleep after triazolam (TRZ) injections at any dose from 0.2 to 1.6 mg/kg, whereas 0.4 mg/kg TRZ given intact rats in the middle of their activity phase significantly increased sleep. Across SCN-lesioned and intact rats, the amount of sleep before an...

journal_title：Neuroscience letters

authors： Edgar DM,Seidel WF,Martin CE,Sayeski PP,Dement WC

更新日期：1991-04-29 00:00:00

abstract：:Sex differences are often reported in spatial abilities. However, some studies show conflicting results, which can be ascribed to the complexity of the variables involved in the visuo-spatial domain. Until a few years ago, it was widely accepted that men outperformed women on almost all spatial tasks. However, recentl...

journal_title：Neuroscience letters

authors： Piccardi L,Iaria G,Ricci M,Bianchini F,Zompanti L,Guariglia C

更新日期：2008-02-20 00:00:00