Abstract:
:This event-related functional Magnetic Resonance Imaging study examined the differential neural activities associated with a Risky-Gains task in 18 healthy individuals of high (n=9) or low (n=9) impulsiveness, according to their scores on the Barratt Impulsiveness Scale (BIS). The neural activities of people belonging to the high and low impulsiveness groups were monitored by a 3T MRI scanner while they were performing the Risky-Gains task. We demonstrated that a stronger activation in the insula-orbitofrontal-parietal regions was found in the high impulsiveness group compared to the low impulsiveness group. However, the levels of activation in the lateral prefrontal and anterior cingulate regions did not differ between the two groups. The findings suggest that the neural substrates of comprehension of cognitive and affective information associated with risk-taking decision making may vary according to the impulsiveness among healthy individuals.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Lee TM,Chan CC,Han SH,Leung AW,Fox PT,Gao JHdoi
10.1016/j.neulet.2008.04.061subject
Has Abstractpub_date
2008-06-20 00:00:00pages
138-41issue
2eissn
0304-3940issn
1872-7972pii
S0304-3940(08)00540-5journal_volume
438pub_type
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