Abstract：
:Using collision tests of orthodromically and antidromically generated spikes, we studied the axonal pathways, axonal projection levels, and soma location of anterior semicircular canal (AC) nerve-activated vestibulospinal neurons in decerebrate cats. AC nerve-activated vestibulospinal neurons (n=74) were mainly located in the ventral portion of the lateral vestibular nuclei and the rostral portion of the descending vestibular nucleus, which is consistent with previous studies. Of these neurons, 15% projected through the ipsilateral (i-) lateral vestibulospinal tract (LVST), 74% projected through the medial vestibulospinal tract (MVST), and 11% projected through the contralateral (c-) LVST. The vast majority (78%) of AC nerve-activated vestibulospinal neurons were activated antidromically only from the cervical segment of the spinal cord; 15% of neurons were activated from the T1 segment and only one neuron was activated from the L3 segment. AC nerve-activated vestibulospinal neurons may primarily target the neck muscles and thus contribute to the vestibulocollic reflex. Most of the c-LVST neurons were also activated antidromically from the oculomotor nucleus, suggesting that they are closely related to the control of combined eye-head movements.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Kitajima N,Sugita-Kitajima A,Bai R,Sasaki M,Sato H,Imagawa M,Kawamoto E,Suzuki M,Uchino Ydoi
10.1016/j.neulet.2006.06.024subject
Has Abstractpub_date
2006-10-02 00:00:00pages
1-5issue
1-2eissn
0304-3940issn
1872-7972pii
S0304-3940(06)00600-8journal_volume
406pub_type
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