Electrophysiological properties of lemniscal afferents in rat after kainic acid lesions in the ventrobasal thalamus.

Abstract:

:Kainic acid (KA) has been largely used as a neurotoxin, and its axon-sparing effect being repeatedly emphasized, on the basis of anatomical and biochemical data. The present study examines this 'axon-sparing' effect from an electrophysiological point of view and demonstrates that lemniscal fibers retain the capacity to convey somesthetic information 5-60 days after an injection of KA in the ventrobasal complex of the thalamus depriving these afferent fibers of their target cells.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Peschanski M,Briand A,Poingt JP,Guilbaud G

doi

10.1016/0304-3940(85)90068-0

subject

Has Abstract

pub_date

1985-08-05 00:00:00

pages

287-92

issue

3

eissn

0304-3940

issn

1872-7972

pii

0304-3940(85)90068-0

journal_volume

58

pub_type

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