Abstract：
:Although rats often show an upright standing behavior the cardiovascular response during the behavior has not yet been fully clarified. In this study we quantified the activity of upright standing behavior in rats using infrared beam detectors and measured cardiovascular variables during the behavior. Rats demonstrated a high level of upright standing activity as they showed the upright posture more than 500 times per day at 10 weeks of age. The average upright standing duration time was less than 10s. Arterial pressure slightly decreased while heart rate increased in response to the behavior and these responses were not affected by sino-aortic denervation. Our results indicate that other mechanisms such as the vestibulo-cardiovascular reflex may completely compensate the lack of the baroreceptor reflex to maintain cardiovascular homeostasis in response to acute positional changes in rats. Moreover rats demonstrate complex integrative mechanisms maintaining cardiovascular homeostasis against the upright standing behavior which frequently occurs in rats.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Waki H,Katahira K,Yamasaki M,Katsuda S,Shimizu T,Maeda Mdoi
10.1016/j.neulet.2008.10.087subject
Has Abstractpub_date
2009-01-02 00:00:00pages
10-4issue
1eissn
0304-3940issn
1872-7972pii
S0304-3940(08)01513-9journal_volume
449pub_type
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