The nigro-striatal and nigro-amygdaloid pathways undergo different degeneration processes in brains of dementia with Lewy bodies.

abstract：:Nociceptin/orphanin FQ (N/OFQ) is an endogenous peptide agonist for the opioid receptor homolog, N/OFQ receptor, and serves for the central control of autonomic functions. Morphological details including the cell types that may account for such N/OFQ functions, however, remain unclear. By using X-gal histochemistry fo...

journal_title：Neuroscience letters

authors： Houtani T,Ikeda M,Kase M,Sato K,Sakuma S,Kakimoto S,Ueyama T,Munemoto Y,Takeshima H,Sugimoto T

更新日期：2003-01-02 00:00:00

abstract：:Sensitisation of the capsaicin receptor, transient receptor potential vanilloid type 1 (TRPV1) ion channel in nociceptive primary sensory neurons (PSN) underlies the development of inflammatory heat hyperalgesia. Removal of the negative-dominant splice variant of the TRPV1 molecule, TRPV1b from TRPV1/TRPV1b heterotetr...

journal_title：Neuroscience letters

authors： Mistry S,Paule CC,Varga A,Photiou A,Jenes A,Avelino A,Buluwela L,Nagy I

更新日期：2014-04-03 00:00:00

abstract：:It is well-established that 17beta-estradiol (17beta-E(2)) confers neuroprotection to male and female rats exposed to focal cerebral ischemia, while less is known about the effects of the hormone under conditions of transient global ischemia. Since translocation of cytochrome c from the mitochondria to the cytosol is ...

journal_title：Neuroscience letters

authors： Bagetta G,Chiappetta O,Amantea D,Iannone M,Rotiroti D,Costa A,Nappi G,Corasaniti MT

更新日期：2004-09-16 00:00:00

abstract：:Nerve growth factor (NGF) protein has been implicated in alterations of cognitive function either following brain damage, selective lesions or aging. Groups of rats were given long-term (48 weeks) oral barbital treatment or tap water and following an extended period of abstinence (14 weeks) were tested for spatial lea...

journal_title：Neuroscience letters

authors： Wahlström G,Archer T,Lärkfors L

更新日期：1992-03-16 00:00:00

abstract：:There is evidence that immune-inflammatory, stress of reactive oxygen and nitrogen species (IO&NS) processes play a role in the neurodegenerative processes observed in Parkinson's disease (PD). The aim of the present study was to investigate peripheral IO&NS biomarkers in PD. We included 56 healthy individuals and 56 ...

journal_title：Neuroscience letters

authors： de Farias CC,Maes M,Bonifácio KL,Bortolasci CC,de Souza Nogueira A,Brinholi FF,Matsumoto AK,do Nascimento MA,de Melo LB,Nixdorf SL,Lavado EL,Moreira EG,Barbosa DS

更新日期：2016-03-23 00:00:00

abstract：:The number of neurons in the primary motor cortex (MI) and the primary somatosensory cortex (SI) were estimated in the same locations of brains from sporadic amyotrophic lateral sclerosis (ALS) cases and controls. The number of MI and SI neurons and Betz cells were significantly decreased in the ALS cases as compared ...

journal_title：Neuroscience letters

authors： Mochizuki Y,Mizutani T,Shimizu T,Kawata A

更新日期：2011-09-26 00:00:00

abstract：:Following the iontophoretic deposition of Phaseolus vulgaris leucoagglutinin (PHA-L) into the rostral ventrolateral medulla (RVL), two-color immunoperoxidase staining was employed to demonstrate contiguity between PHA-L-immunoreactive (PHA-LI) varicose fibers and boutons and brainstem monoaminergic cells. Black-staine...

journal_title：Neuroscience letters

authors： Nicholas AP,Hancock MB

更新日期：1991-01-14 00:00:00

abstract：:Amyloid beta (Aβ) is the main component of the amyloid plaques that accumulate in the brains of Alzheimer patients. Here, we reported the protective role of Formononetin (Form) against Aβ25-35-induced neurotoxicity in HT22 cells. We found that Form significantly increased the viability of HT22 cells but decreased the ...

journal_title：Neuroscience letters

authors： Chen L,Ou S,Zhou L,Tang H,Xu J,Guo K

更新日期：2017-02-03 00:00:00

abstract：:An approximately 54-kDa protein that has binding sites for the competitive N-methyl-D-aspartate (NMDA) receptor antagonists 3-((+-)-2-carboxypiperazine-4-yl)-propyl-1-phosphonic acid (CPP) and (+-)-(E)-2-amino-4-propyl-5-phosphonopentenoic acid (CGP 39653) was purified from rat brain synaptic membranes. Polyclonal ant...

journal_title：Neuroscience letters

authors： Eggeman KT,Pal R,Walsh J,Kumar KN,Michaelis EK

更新日期：1993-08-20 00:00:00

abstract：:Localization of the epileptogenic zone (EZ) is an important issue in epileptology, even though there is not a unique definition of the epileptic focus. By using complex network analysis of electrocorticographic (ECoG) data we identify three singular areas in the temporal lobe of epileptic patients, the node with highe...

journal_title：Neuroscience letters

authors： Ortega GJ,Sola RG,Pastor J

更新日期：2008-12-12 00:00:00

abstract：:Glucose metabolism and tricarboxylic acid cycle (TCA) kinetics have been shown to decline in brain with age in various animal species. This study examined TCA cycle kinetics and age in Brown-Norway Fischer 344 rats. Using [1-(13)C]glucose infused over 10, 30, 60 or 100 min, and following the label through the TCA cycl...

journal_title：Neuroscience letters

authors： Perron JT,Tyson RL,Sutherland GR

更新日期：2000-03-10 00:00:00

abstract：:Alzheimer's disease is correlated with neuronal degeneration and loss of neuronal precursors in different parts of the brain. It has been found disturbance in the homeostasis neural stem cells (NSCs) can cause neurodegeneration. Morphine, an analgesic agent, can disrupt the dynamic and normal state of NSCs. However, m...

journal_title：Neuroscience letters

authors： Salarinasab S,Nourazarian A,Nikanfar M,Abdyazdani N,Kazemi M,Feizy N,Rahbarghazi R

更新日期：2017-11-01 00:00:00

abstract：:Synthetic soluble Aβ oligomers are often used as a surrogate for biologic material in a number of model systems. We compared the activity of Aβ oligomers (synthetic and cell culture media derived) on the human SH-SY5Y neuroblastoma and C2C12 mouse myoblast cell lines in a novel, modified MTT assay. Separating oligomer...

journal_title：Neuroscience letters

authors： Weidner AM,Housley M,Murphy MP,Levine H 3rd

更新日期：2011-06-15 00:00:00

abstract：:Immobilization stress induced interleukin-1 beta (IL-1 beta) mRNA in the rat hypothalamus. IL-1 beta mRNA was induced at 30 min after the start of immobilization, reached a maximum at 60 min and then was still detected with a decreased level at 120 min. However, 240 min after the start of the immobilization, IL-1 beta...

journal_title：Neuroscience letters

authors： Minami M,Kuraishi Y,Yamaguchi T,Nakai S,Hirai Y,Satoh M

更新日期：1991-02-25 00:00:00

abstract：:Recent findings from our and other laboratories indicate that cell cycle-related phenomena may play a key role in the formation of Alzheimer-type pathology and neuronal cell death in both Alzheimer's and cerebro-vascular diseases. In this study we examine the expression patterns of cyclins A, B1, D1 and E in neuronal ...

journal_title：Neuroscience letters

authors： Smith MZ,Nagy Z,Esiri MM

更新日期：1999-08-13 00:00:00

abstract：:To verify the hypothesis that the control of movement by the cortical masticatory area (CMA) is particularly important at the beginning of the mastication, we compared movements before and after bilateral CMA ablation. After ablation, the animal could not manipulate food placed in the front of the mouth for several da...

journal_title：Neuroscience letters

authors： Enomoto S,Schwartz G,Lund JP

更新日期：1987-11-23 00:00:00

abstract：:Although aging-related alterations in the auditory sensory memory and involuntary change discrimination have been widely studied, it remains controversial whether the mismatch negativity (MMN) or its magnetic counterpart (MMNm) is modulated by physiological aging. This study aimed to examine the effects of aging on mi...

journal_title：Neuroscience letters

authors： Cheng CH,Baillet S,Hsiao FJ,Lin YY

更新日期：2013-06-07 00:00:00

abstract：:Mouse neuroblastoma x rat glioma hybrid cells (N x G, NG108-15) were used to study the mechanism of Ca(2+)-current (ICa) inhibition by 5-hydroxytryptamine (5-HT). 5-HT caused a dose-dependent decrease of ICa which was abolished by ICS 205-930 (10)(-8) M) while 2-methyl-5-HT was an agonist. Intracellular infusion of GD...

journal_title：Neuroscience letters

authors： Eckert R,Utz J,Trautwein W

更新日期：1993-04-16 00:00:00

abstract：:The retrograde transport of receptor-bound opiate was markedly enhanced in the vagus nerves of rats housed for 25 days in an atmosphere of ethanol vapor. This increase disappeared after 8 days of withdrawal as did the animal preference for ethanol. In contrast, the axonal transport of muscarinic receptors in sciatic n...

journal_title：Neuroscience letters

authors： Laduron PM,De Witte PA

更新日期：1987-06-26 00:00:00

abstract：:Serial sections of human brainstem were used to determine the total number of pigmented cells in locus coeruleus and, by immunohistochemical staining using an antiserum directed against human dopamine-beta-hydroxylase (DBH), the number of DBH-positive cells. In 12 brains from elderly control and dementia subjects ther...

journal_title：Neuroscience letters

authors： Iversen LL,Rossor MN,Reynolds GP,Hills R,Roth M,Mountjoy CQ,Foote SL,Morrison JH,Bloom FE

更新日期：1983-08-19 00:00:00

abstract：:The normal development of the superior collicular map of auditory space in the guinea pig requires visual experience (Eur. J. Neurosci., 2 (1990) 682-692). The possible role of the visual cortex in this process was assessed by unilateral removal of the cortex prior to the crucial period during which visual experience ...

journal_title：Neuroscience letters

authors： Withington DJ,Binns KE,Keating MJ

更新日期：1991-04-29 00:00:00

abstract：:The brain and nasal region of a fetal (124 days) female rhesus macaque (Macaca mulatta) were fixed in situ, decalcified, sectioned and treated for the immunocytochemical demonstration of LHRH. Immunoreactive neurons and fibers were found in expected sites and also in sites not reported to date in primates: there was a...

journal_title：Neuroscience letters

authors： Witkin JW

更新日期：1987-08-18 00:00:00

abstract：:Traumatic brain injury (TBI) is a major cause of neurological disability across all ages, but the elderly are particularly vulnerable and have a worse prognosis than younger individuals. To advance the understanding of long-term pathogenesis induced by TBI in the elderly, aged mice (21 -- 24 months) were given a contr...

journal_title：Neuroscience letters

authors： Onyszchuk G,LeVine SM,Brooks WM,Berman NE

更新日期：2009-03-13 00:00:00

abstract：:Interhemispheric coherence for 19 channel EEG activity collected over a three year period from 184 men and women who relaxed in a quiet, darkened chamber showed significant increased coherence between caudal temporal regions for the 11 Hz frequency band during increased (>∼8 nT) global geomagnetic activity at the time...

journal_title：Neuroscience letters

authors： Saroka KS,Caswell JM,Lapointe A,Persinger MA

更新日期：2014-02-07 00:00:00

abstract：:The effects of administration of 1-oleoyl-2-docosahexaenoyl-sn-glycero-3-phosphorylcholine (O-DH-PC), a kind of lecithin, and of glycerophosphorylcholine (GPC) on sleep were investigated in male F344 rats. Intracerebroventricular administration of O-DH-PC at a dose of 10 micrograms/rat induced significant increase in ...

journal_title：Neuroscience letters

authors： Hashimoto M,Gong XW,Izaki Y,Iriki M,Hibino H

更新日期：1993-08-06 00:00:00

abstract：:The present study was designed to test the hypothesis that acute administration of alcohol (ethanol) to primary cultured cerebral vascular smooth muscle cells will cause lipid peroxidation, inhibition of IkappaB phosphorylation, and inhibition of nuclear transcription factor-kappa B (NF-kappaB). Ethanol (10, 25, 100 m...

journal_title：Neuroscience letters

authors： Altura BM,Gebrewold A,Zhang A,Altura BT

更新日期：2002-06-07 00:00:00

abstract：:Extracellular choline-dependency of acetylcholine (ACh) synthesis was examined in rat hippocampal slices. In the presence of hemicholinium-3 (HC-3, 5 microM), extracellular choline-dependent ACh synthesis appeared to consist of two different components. The first component (saturated at up to 50 microM choline) was de...

journal_title：Neuroscience letters

authors： Suzuki T,Kashima Y,Kawashima K

更新日期：1989-10-23 00:00:00

abstract：:Depression is one of the most prevalent challenges of mental conditions. Yet its exact etiology has not been clear. Chronic stress increases the production of cytokines, which can lead to depression. Hepcidin, an iron modulator, is involved in the inflammation process as well as iron homeostasis. This study was design...

journal_title：Neuroscience letters

authors： Farajdokht F,Soleimani M,Mehrpouya S,Barati M,Nahavandi A

更新日期：2015-02-19 00:00:00

abstract：:The projections of neurons, in and around the A1 noradrenergic cell group of the caudal ventrolateral medulla (VLM), to nucleus of the solitary tract (NTS) were studied in the cat using the anterograde transport of Phaseolus vulgaris leucoagglutinin (PHA-L). PHA-L was micro-iontophoresed into the region of the A1 nora...

journal_title：Neuroscience letters

authors： Roder S,Ciriello J

更新日期：1992-01-06 00:00:00

abstract：:Apolipoprotein(a) [apo(a)] is a highly polymorphic glycoprotein which has been suggested to play a role in Alzheimer's disease (AD). Plasma lipoprotein(a) [Lp(a)] levels and the differential expression of apo(a) isoforms were analyzed in 73 sporadic AD patients compared with 73 age- and gender-matched healthy controls...

journal_title：Neuroscience letters

authors： Emanuele E,Peros E,Tomaino C,Feudatari E,Bernardi L,Binetti G,Maletta R,D'Angelo A,Montagna L,Bruni AC,Geroldi D

更新日期：2004-02-26 00:00:00