1-Oleoyl-2-docosahexaenoyl phosphatidylcholine increased paradoxical sleep in F344 rats.

abstract：:Methyl-CpG binding protein 2 (MECP2) is a chromosome-binding protein that regulates the development and maintenance of brain circuits. Altered function of the protein product of MECP2 plays an important role in the etiology of many neurodevelopmental disorders. Mutations involving a loss of function are implicated in ...

journal_title：Neuroscience letters

authors： Tropea D,Mortimer N,Bellini S,Molinos I,Sanfeliu A,Shovlin S,McAllister D,Gill M,Mitchell K,Corvin A

更新日期：2016-05-16 00:00:00

abstract：:In rats anesthetized with pentobarbital or a mixture of urethane and chloralose, horseradish peroxidase (HRP) was injected into the intermediolateral column of the spinal cord (Th7 and Th9) or the posterior pituitary lobe. HRP positive cells were found mainly in the dorsomedial part of the paraventricular nuclease (PV...

journal_title：Neuroscience letters

authors： Ono T,Nishino H,Sasaka K,Muramoto K,Yano I,Simpson A

更新日期：1978-11-01 00:00:00

abstract：:The expression of five muscarinic receptor mRNAs (m1, m2, m3, m4, m5) was examined in neostriatum, hippocampus and frontal cortex of 3, 18, and 33 month old rats. Transcripts for ml (3.0 kb), m2 (6.2 kb), m3 (4.5 kb) and m4 (3.3 kb) were detected in all brain regions studied. A 6.0 kb transcript for the m5 muscarinic ...

journal_title：Neuroscience letters

authors： Lee HJ,Clagett-Dame M,Heideman W,Weiler MS

更新日期：1994-06-20 00:00:00

abstract：:Genetic factors play an important role in Parkinson's disease (PD) and vary from different races. A previous genome-wide association study (GWAS) identified 17 novel risk loci that were associated with PD in Caucasians. Several subsequent studies investigated the association between these loci and PD in Chinese popula...

journal_title：Neuroscience letters

authors： Hu X,Mao C,Hu Z,Zhang Z,Zhang S,Yang Z,Fan Y,Fan L,Zheng H,Yang J,Liu Y,Yuan Y,Wang Y,Shi C,Xu Y

更新日期：2020-04-23 00:00:00

abstract：:The pharmacological properties of presynaptic calcium (Ca) channels on rat hippocampal mossy fiber synaptosomes were characterized by determining the inhibitory potencies for various classes of Ca antagonists on depolarization-induced Ca mobilization and the release of dynorphin A(1-8)-like immunoreactivity (Dyn-LI). ...

journal_title：Neuroscience letters

authors： Terrian DM,Damron DS,Dorman RV,Gannon RL

更新日期：1989-12-04 00:00:00

abstract：:Neuronal nAChRs are pentameric transmembrane proteins which function as ligand-gated ion channels and are composed of multiple alpha and beta subunits. Nine neuronal nAChR alpha subunit genes (alpha2-alpha10) and three nAChR beta subunit genes (beta2-beta4) have been identified. nAChR subtypes are heteromers, composed...

journal_title：Neuroscience letters

authors： Danthi S,Boyd RT

更新日期：2006-05-29 00:00:00

abstract：:The CA1 region of the rat hippocampal slice generates spontaneous electrographic seizures (field bursts) when exposed to ACSF containing < or = 0.2 mM calcium. It has been proposed that, particularly during the early part of a field burst, synchronised activity in small independent aggregates of neurons results in low...

journal_title：Neuroscience letters

authors： Fox JE,Bikson M,Jefferys JG

更新日期：2007-01-10 00:00:00

abstract：:The present study was aimed at determining whether human recombinant hepatocyte growth factor (HGF) ameliorates cerebral edema induced by microsphere embolism (ME). Rats were injected with 700 microspheres (48 microm in diameter). Continuous administration of HGF at 13 microg/3 days/animal into the right ventricle was...

journal_title：Neuroscience letters

authors： Takeo S,Takagi N,Takagi K,Date I,Ishida K,Besshoh S,Nakamura T,Tanonaka K

更新日期：2008-12-19 00:00:00

abstract：:Prolyl endopeptidase (PEP; EC 3.4.21.26) cleaves the Pro-Arg bond of arginine-vasopressin (AVP). This study investigated the effects of PEP inhibitors, 1-[1-(benzyloxycarbonyl)-L-prolyl]prolinal (Z-Pro-prolinal) and 1-[3-(2-indanylacetyl)-L-thioprolyl]pyrrolidine (Z-321), on the AVP content in the septum of rats. Oral...

journal_title：Neuroscience letters

authors： Miura N,Shibata S,Watanabe S

更新日期：1995-08-18 00:00:00

abstract：:Noradrenergic fibers from the locus ceruleus were identified in close proximity to brain microvessels, and adrenoceptors exist in isolated brain capillaries. Yet, proof of innervation of brain microvessels by locus ceruleus remains elusive. We now demonstrate increased density of beta-adrenoceptors by pindolol binding...

journal_title：Neuroscience letters

authors： Kalaria RN,Stockmeier CA,Harik SI

更新日期：1989-02-13 00:00:00

abstract：:The effect of electrical stimulation of the dorsal hippocampus on accumbens dopamine release was examined. Stimulation of the kindled hippocampus that produced stage 3 seizures evoked a brief increase in extracellular DA and DOPAC levels in the contralateral nucleus accumbens. In contrast, similar stimulation early in...

journal_title：Neuroscience letters

authors： Strecker RE,Moneta ME

更新日期：1994-08-01 00:00:00

abstract：:The expression of class I and class II histocompatibility antigens by myelin basic protein (MBP)-positive oligodendrocytes, in response to exogenous cytokines, has been investigated in vitro. It has been found that interferon-gamma (IFN-gamma), although capable of class I induction, does not induce class II on oligode...

journal_title：Neuroscience letters

authors： Turnley AM,Miller JF,Bartlett PF

更新日期：1991-02-11 00:00:00

abstract：:Rho kinase (ROCK) regulates the functions of several target proteins via its kinase activity. Therefore, ROCK activity inhibition may provide new possibilities of controlling the in vitro neuronal differentiation of embryonic stem (ES) cells. When we investigated the effects of the ROCK inhibitor Y-27632 on ES cell di...

journal_title：Neuroscience letters

authors： Kamishibahara Y,Kawaguchi H,Shimizu N

更新日期：2016-02-26 00:00:00

abstract：:The comorbidity between migraine and depression not only provides a major treatment challenge, but also represents a heavy burden on society. However, the relationship between depression and migraine and their molecular biological mechanisms remain unclear. This study investigated the effects of depression elicited by...

journal_title：Neuroscience letters

authors： Zhang M,Dai W,Liang J,Chen X,Hu Y,Chu B,Pan M,Dong Z,Yu S

更新日期：2013-09-13 00:00:00

abstract：:Diurnal variation of N-acetylserotonin in the retina was studied in male rats housed under a photoperiod of 12 h light and 12 h darkness (lights on at 06.00 h) for two weeks. N-acetylserotonin was extracted from the retina by ethyl acetate at pH less than or equal to 3 and was determined by radioimmunoassay. There is ...

journal_title：Neuroscience letters

authors： Pang SF,Yu HS,Tang PL

更新日期：1981-01-20 00:00:00

abstract：:Acetaldehyde (AcH) and salsolinol play important roles in the central effects of ethanol. This study aimed to investigate the effect of administration of AcH on dopamine (DA), DA-derived salsolinol and serotonin (5-HT) levels in the dorsal striatum of Aldh2-knockout (Aldh2-KO) and C57BL/6 N (WT) mice. Animals were tre...

journal_title：Neuroscience letters

authors： Ito A,Jamal M,Ameno K,Tanaka N,Takakura A,Kawamoto T,Kitagawa K,Nakayama K,Matsumoto A,Miki T,Kinoshita H

更新日期：2018-10-15 00:00:00

abstract：:Functional neuroimaging suggests asymmetries of memory encoding and retrieval in the prefrontal lobes, but different hypotheses have been presented concerning the nature of prefrontal hemispheric specialization. We studied an associative memory task involving pairs of Kanji (Chinese) pictographs and unfamiliar abstrac...

journal_title：Neuroscience letters

authors： Epstein CM,Sekino M,Yamaguchi K,Kamiya S,Ueno S

更新日期：2002-03-01 00:00:00

abstract：:Acute urinary bladder distension (AUBD) and colorectal distension (CRD) activated mechanical afferents from the urinary bladder and colon and the activated afferent signaling affected visceral organ behavior. AUBD and CRD have been reported to affect the arterial blood pressure (ABP) response in the rat. We hypothesiz...

journal_title：Neuroscience letters

authors： Chen SS,Yang CC,Chien CT

更新日期：2008-10-10 00:00:00

abstract：:The localisation of transforming growth factor-beta-2 (TGF-beta 2) in skeletal muscles was investigated with immunohistochemistry. In neonates, TGF-beta 2 was distributed throughout the muscle fibres but as the fibres matured TGF-beta 2 became restricted to the circumference of a small subpopulation of nuclei. These n...

journal_title：Neuroscience letters

authors： McLennan IS,Koishi K

更新日期：1994-08-15 00:00:00

abstract：:The effects of a series of chloride transport blockers (ethacrynate, furosemide, torasemide, 4,4'-diisothiocyano-2,2'-disulfonic acid stilbene and diphenylcarboxylate) on Cl(-)-dependent L-[3H]glutamate (Glu) binding were tested in rat brain membranes, Cl-transport blockers inhibit the Ca2+/Cl(-)-induced increase in L...

journal_title：Neuroscience letters

authors： Recasens M,Pin JP,Bockaert J

更新日期：1987-02-24 00:00:00

abstract：:Amyloid precursor protein (APP) is strongly related to the onset of Alzheimer's disease. It possesses cleavage sites for beta- and gamma-secretases, and the resulting cleaved products (amyloid-beta peptides) are capable of causing neurotoxicity. Such cleavage is promoted by the Swedish and London mutations (APPSwe/Lon...

journal_title：Neuroscience letters

authors： Hashimoto T,Ogino K,Shin RW,Kitamoto T,Kikuchi T,Shimizu N

更新日期：2010-01-22 00:00:00

abstract：:Recent discovery of pathogenic mutations in the leucine-rich repeat kinase 2 (LRRK2) gene in Parkinson's disease (PD) patients in different ethnic groups have raised a hope of diagnostic screening and genetic counseling. We investigated the six most commonly reported mutations in LRRK2 gene among Indian PD patients, u...

journal_title：Neuroscience letters

authors： Punia S,Behari M,Govindappa ST,Swaminath PV,Jayaram S,Goyal V,Muthane UB,Juyal RC,Thelma BK

更新日期：2006-12-01 00:00:00

abstract：:Recent studies have shown an association between Parkinson disease (PD) and mutations in the gene encoding the lysosomal enzyme glucocerebrosidase (GBA), which is deficient in patients with Gaucher disease. In Asian populations, 2 mutational analysis studies have been performed in all exons of GBA; one study in a Japa...

journal_title：Neuroscience letters

authors： Choi JM,Kim WC,Lyoo CH,Kang SY,Lee PH,Baik JS,Koh SB,Ma HI,Sohn YH,Lee MS,Kim YJ

更新日期：2012-04-11 00:00:00

abstract：:A compound action potential of short latency was recorded from the ganglion mesencephali extrolaterale in response to both the fish's own electric organ discharge and electric stimulation of the whole fish or a branch of the posterior lateral line nerve. The time difference between the response in the nerve, 16 mm fro...

journal_title：Neuroscience letters

authors： Enger PS,Libouban S,Szabo T

更新日期：1976-05-01 00:00:00

abstract：:Although neural stem cell (NSC) transplantation has been investigated as a promising tool for reconstituting damaged brains, recent evidences suggest that NSCs may rescue the brain via paracrine effects rather than by direct cell replacements. In this study, we attempted to determine the neuroprotective effect of NSC-...

journal_title：Neuroscience letters

authors： Lim HC,Lee ST,Chu K,Joo KM,Kang L,Im WS,Park JE,Kim SU,Kim M,Cha CI

更新日期：2008-04-25 00:00:00

abstract：:Basal serotonin (5-HT) release, measured in the presence of imipramine, was significantly reduced in slices of hippocampus, n. accumbens and frontal cortex from rats subjected to forced swim test and chronic isolation. Only in the hippocampus, in the two animal models of depression, K-stimulated release was increased....

journal_title：Neuroscience letters

authors： Jaffe EH,De Frias V,Ibarra C

更新日期：1993-11-12 00:00:00

abstract：:The streptozotocin (STZ)-induced diabetes model is widely used for the induction of neuropathy in the rat. In this model, diabetic animals often display chronic illness, which raises objections not only on ethical but also on scientific grounds. In this study, the investigators set out to determine the impact of bodyw...

journal_title：Neuroscience letters

authors： Hoybergs YM,Biermans RL,Meert TF

更新日期：2008-05-02 00:00:00

abstract：BACKGROUND:A single session of aerobic exercise is linked to faster motor responses; however, the effect on rate of short-term learning is less clear. The objective was to evaluate the influence of a single bout of aerobic exercise on the rate of short-term acquisition of a shape-letter association task requiring a mot...

journal_title：Neuroscience letters

authors： Sage MD,Beyer KB,Laylor M,Liang C,Roy EA,McIlroy WE

更新日期：2016-08-26 00:00:00

abstract：:Electrical stimulation in the lateral midbrain reticular formation (LRF) inhibited the responses of spinal dorsal horn neurons to noxious (50 degrees C) skin heating. Systemic administration of naloxone (0.1-2 mg/kg) had no effect on inhibition produced by LRF stimulation in 10 units, while this inhibition was partial...

journal_title：Neuroscience letters

authors： Carstens E,Zimmermann M

更新日期：1980-12-01 00:00:00

abstract：:The effect of chronic salt loading on urocortin-like immunoreactivity (Ucn-IR) was investigated in the rat hypothalamo-neurohypophysial system. In control rats a few Ucn-IR neurons were observed scattered throughout the supraoptic nucleus (SON) and few in the paraventricular nucleus (PVN). A small number of Ucn-IR fib...

journal_title：Neuroscience letters

authors： Hara Y,Ueta Y,Isse T,Kabashima N,Shibuya I,Hattori Y,Yamashita H

更新日期：1997-05-16 00:00:00