Chloride transport blockers inhibit the chloride-dependent glutamate binding to rat brain membranes.

abstract：:Spontaneous action potentials were recorded longitudinally for 4-7 weeks from dissociated rat occipital cortex cells cultured on planar multi-electrode plates, during their development from isolated neurons into synaptically connected neuronal networks. Activity typically consisted of generalized bursts lasting up to ...

journal_title：Neuroscience letters

authors： Van Pelt J,Corner MA,Wolters PS,Rutten WL,Ramakers GJ

更新日期：2004-05-06 00:00:00

abstract：:The contribution of NMDA receptors to neuronal hyperexcitability following in vitro ethanol withdrawal was examined using afterdischarges (ADs) in rat dentate gyrus as a model system. ADs were evoked by high frequency stimuli and blocked by N-methyl-D-aspartate (NMDA) receptor antagonists. Ethanol (75 mM) inhibited AD...

journal_title：Neuroscience letters

authors： Morrisett RA

更新日期：1994-02-14 00:00:00

abstract：:To evaluate possible prespike field synchronizations, its relation to both interictal discharges and postspike return to baseline, penicillin-induced cortical interictal discharges were recorded in anaesthetized rabbits by magnetoencephalography (MEG) and electrocorticography (EcoG). Statistical parameters of spatial ...

journal_title：Neuroscience letters

authors： Zwiener U,Eiselt M,Giessler F,Nowak H

更新日期：2000-08-04 00:00:00

abstract：:Distributions of one sensory and 13 motor axons to intrafusal fibers in a human spindle from the biceps brachii muscle were reconstructed from serial, 1 micron thick transverse sections. The primary afferent was distributed predominantly to nuclear bag fibers. Motor innervation in the human spindle was characterized b...

journal_title：Neuroscience letters

authors： Kucera J

更新日期：1986-01-16 00:00:00

abstract：:G protein-coupled receptor kinase-interactor 2 (GIT2) is a signaling scaffold protein that also functions as GTPase-activating protein (GAPs) for ADP-ribosylation factor (Arf) small GTP-binding proteins. GIT2 has been implicated in the regulation of G protein-coupled receptor trafficking and cell adhesion and migratio...

journal_title：Neuroscience letters

authors： Schmalzigaug R,Rodriguiz RM,Phillips LE,Davidson CE,Wetsel WC,Premont RT

更新日期：2009-02-20 00:00:00

abstract：:The effect of preconditioning (PC) on the changes of nerve growth factor-induced gene A (NGFI-A) expression induced by severe hypobaric hypoxia was studied by in situ hybridization. A PC consisted of three trials of mild hypobaric hypoxia (360 Torr, 2 h) spaced at 24 h. The last trial was followed by severe hypoxia (S...

journal_title：Neuroscience letters

authors： Rybnikova E,Tulkova E,Pelto-Huikko M,Samoilov M

更新日期：2002-08-23 00:00:00

abstract：:Hrk, a regulator of cell death, belongs to the family of pro-apoptotic BH3-only proteins and is known to induce apoptosis in nerve tissue. We examined Hrk gene expression to clarify the role of BH3-only proteins in apoptosis of retinal ganglion cells (RGCs) after optic nerve transection in the adult rat. Reverse trans...

journal_title：Neuroscience letters

authors： Wakabayashi T,Kosaka J,Hommura S

更新日期：2002-01-25 00:00:00

abstract：:The association between (GT)n dinucleotide repeats in monoamine oxidase gene loci, monoamine oxidase A (MAOA) and B (MAOB), and Parkinson's disease (PD), Alzheimer's disease (AD), and Lewy body variant (LBV) of AD were determined. MAOA-GT polymorphisms were significantly associated with pure AD and LBV. MAOA-GT allele...

journal_title：Neuroscience letters

authors： Takehashi M,Tanaka S,Masliah E,Ueda K

更新日期：2002-07-19 00:00:00

abstract：:Antidepressive medication and electroconvulsive therapy (ECT) increase hippocampal neurogenesis by promoting expression of trophic factors, including brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF). The aims were to test for an association between the VEGF 2578 C/A polymorphism a...

journal_title：Neuroscience letters

authors： Viikki M,Anttila S,Kampman O,Illi A,Huuhka M,Setälä-Soikkeli E,Mononen N,Lehtimäki T,Leinonen E

更新日期：2010-06-25 00:00:00

abstract：:Cyclophosphamide (CP) has been used as an antitumour agent or immunosuppressant clinically, though the potential biological role of CP in the central nervous system (CNS) has not been clarified. In the present study, we found that pretreatment with CP prevented neuronal cell death caused by serum deprivation in cultur...

journal_title：Neuroscience letters

authors： Kitazawa H,Numakawa T,Adachi N,Kumamaru E,Tuerxun T,Kudo M,Kunugi H

更新日期：2010-02-12 00:00:00

abstract：:The dopaminergic system has been proposed to be one of the innervations in controlling the mammalian pineal gland function. The dopamine receptors have been characterized in the pineal and the biphasic effects of dopamine on melatonin production have been demonstrated. Recently, the site of dopamine transporter (DAT),...

journal_title：Neuroscience letters

authors： Phansuwan-Pujito P,Boontem P,Chetsawang B,Ebadi M,Govitrapong P

更新日期：2006-07-31 00:00:00

abstract：:We investigated whether the presence of unimodal or bimodal (synchronous) distractors would affect temporal order judgments (TOJs) for pairs of asynchronous audiovisual target stimuli. Participants made unspeeded TOJs regarding which of a pair of auditory and visual stimuli, presented at different stimulus onset async...

journal_title：Neuroscience letters

authors： Vatakis A,Spence C

更新日期：2006-11-06 00:00:00

abstract：:The in vivo effects of the alpha 2-adrenoceptor idazoxan, rauwolscine and phentolamine on alpha 2-auto/heteroreceptors and 5-HT1A autoreceptors modulating the synthesis of dopa/noradrenaline and 5-HTP/serotonin were assessed in rats, using the accumulation of dopa and 5-HTP after decarboxylase inhibition as a measure ...

journal_title：Neuroscience letters

authors： Lladó J,Esteban S,García-Sevilla JA

更新日期：1996-11-01 00:00:00

abstract：:The purpose of the study was to investigate the accuracy of location of equivalent current dipoles estimated by the dipole tracing method (DT) utilizing a realistic 3-shell (scalp-skull-brain) head model (SSB-DT). Three patients with intractable complex partial seizures, diagnosed as having typical temporal seizures w...

journal_title：Neuroscience letters

authors： Homma I,Masaoka Y,Hirasawa K,Yamane F,Hori T,Okamoto Y

更新日期：2001-05-18 00:00:00

abstract：:Neuromelanin (NM)-containing dopaminergic neurons in the substantia nigra are selectively vulnerable in Parkinson's disease (PD), suggesting the involvement of NM in the pathogenesis. NM is composed of protein, lipid, trace metals and melanin component, a mixture of eumelanin produced from dopamine (DA)-quinone and ph...

journal_title：Neuroscience letters

authors： Naoi M,Yi H,Maruyama W,Inaba K,Shamoto-Nagai M,Akao Y,Gerlach M,Riederer P

更新日期：2009-11-13 00:00:00

abstract：:Rabbit retinal Müller cells were isolated by means of papaine and mechanical dissociation. These cells were shown to have a well preserved morphology and to preserve viability for many hours. Intense wheat germ agglutinin binding occurs on the photoreceptor side of Müller cells, especially in the microvillous region. ...

journal_title：Neuroscience letters

authors： Reichenbach A,Dettmer D,Brückner G,Neumann M,Birkenmeyer G

更新日期：1985-03-22 00:00:00

abstract：:In striatal neurons in primary culture quisqualate potently stimulated the formation of inositol phosphates via a metabotropic receptor we recently termed Qp in order to distinguish it from the classical ionotropic quisqualate receptor termed Qi. Here we show that 10 microM of quisqualate activated in a rapid and tran...

journal_title：Neuroscience letters

authors： Manzoni OJ,Finiels-Marlier F,Sassetti I,Blockaert J,le Peuch C,Sladeczek FA

更新日期：1990-02-05 00:00:00

abstract：:The present work describes the formation of a transient efferent axonal projection from the isthmo-optic nucleus (ION) to the ipsilateral optic tectum of the chick embryo. Local application of either the carbocyanine dye DiI or rhodamine-B-isothiocyanate (RITC) to the superficial layers of the optic tectum resulted in...

journal_title：Neuroscience letters

authors： Wizenmann A,Thanos S

更新日期：1990-06-08 00:00:00

abstract：:Projection of the vagal C-afferent to the insular cortex was examined in rats. Electrical activation of the C-afferent resulted in two cortical field potentials in the anterior insula. They were independent of each other and neither of them was attributed to the specific thalamic projection. These results imply that v...

journal_title：Neuroscience letters

authors： Ito S

更新日期：1992-12-14 00:00:00

abstract：:An attempt was made to identify the immunoreactive substance P (SP) released from isolated rat spinal cords using reversed-phase high-performance liquid chromatography (HPLC) combined with radioimmunoassay (RIA) for SP. Soaking the spinal cords of newborn rats in Krebs solution containing 90 mM K+ evoked a release of ...

journal_title：Neuroscience letters

authors： Akagi H,Otsuka M,Yanagisawa M

更新日期：1980-12-01 00:00:00

abstract：:In order to clarify the participation of substance P in the expression of opiate withdrawal, we have investigated the effects induced by the new selective neurokinin-1 antagonist RP 67580 on naloxone-induced morphine withdrawal syndrome in rats. Intracerebroventricular administration of RP 67580 elicited a decrease in...

journal_title：Neuroscience letters

authors： Maldonado R,Girdlestone D,Roques BP

更新日期：1993-06-25 00:00:00

abstract：:The left adrenal gland of the rat was perfused in vitro via the adrenal vein with Krebs-bicarbonate solution to study accumulation of exogenous catecholamines and secretion of endogenous norepinephrine and epinephrine by exposing the gland to various sympathomimetic agents. Perfusions with high concentrations of norep...

journal_title：Neuroscience letters

authors： Wakade AR,Wakade TD

更新日期：1984-09-07 00:00:00

abstract：:Thoracolumbar and lumbosacral spinal segments that receive afferent input from the descending colon and rectum were stained immunocytochemically for c-Fos- and c-Jun-like proteins following repetitive, noxious colorectal distention (CRD). Noxious CRD (80 mmHg) resulted in significantly more c-Fos- and c-Jun-like immun...

journal_title：Neuroscience letters

authors： Traub RJ,Herdegen T,Gebhart GF

更新日期：1993-10-01 00:00:00

abstract：:The intergeniculate leaflet (IGL) of the lateral geniculate complex is marked by the presence of neuro-peptide Y-containing neurons that project to the suprachiasmatic nuclei (SCN) of the hypothalamus. In the present study, we demonstrate that both the IGL and SCN in the hamster and rat are specifically delineated by ...

journal_title：Neuroscience letters

authors： Morin LP,Johnson RF,Moore RY

更新日期：1989-04-24 00:00:00

abstract：:We examined by immunohistochemistry the effect of salt loading on the expression of tyrosine hydroxylase (TH), aromatic L-amino acid decarboxylase (AADC), and GTP cyclohydrolase I (GCH) in Purkinje cells of the mouse cerebellum. In control mice, only a few Purkinje cells were positive for TH or AADC. No Purkinje cells...

journal_title：Neuroscience letters

authors： Sakai M,Fujii T,Karasawa N,Arai R,Nagatsu I

更新日期：1995-07-14 00:00:00

abstract：:In this study, it was investigated whether context-dependent sensitization of catalepsy changes the firing pattern in striatum. Rats were treated with either haloperidol (0.5 mg/kg i.p.) or saline, and tested on catalepsy with a concomitant single-unit measurement of the spiny I activity. Administration of haloperidol...

journal_title：Neuroscience letters

authors： Frank ST,Schmidt WJ

更新日期：2004-01-02 00:00:00

abstract：:Tonsils have a privileged situation in the immune system in that they are in touch with the environment. Melatonin is a hormone that is influenced by the circadian environmental variations of dark-light and is a modulator of the immune system. We have studied a group of thirty five children with recurrent acute tonsil...

journal_title：Neuroscience letters

authors： Lopez-Gonzalez MA,Guerrero JM,Sanchez B,Delgado F

更新日期：1998-05-15 00:00:00

abstract：OBJECTIVE:Exploring the impact of glucocerebrosidase gene (GBA) polymorphisms and mutations on the pathogenesis of Parkinson's disease dementia (PDD) plays an important role in the diagnosis and treatment of this disease. This meta-analysis aimed to investigate the effects of GBA polymorphisms and mutations on the risk...

journal_title：Neuroscience letters

authors： Zhang Y,Chen J,Xu C,Feng J,Li J

更新日期：2020-01-01 00:00:00

abstract：:Cat odor elicits defensive responses in rats that are modified by repeated exposure to the odor. We explored the neural correlates of this adaptation using FosB/DeltaFosB immunohistochemistry. Rats were given 3 x60 min exposures to either a worn cat collar (repeated cat odor group) or unworn cat collar (control group)...

journal_title：Neuroscience letters

authors： Staples LG,McGregor IS,Hunt GE

更新日期：2009-09-22 00:00:00

abstract：:Neurons within the hypothalamic paraventricular nuclei (PVN) have been antidromically invaded following electrical stimulation within the pons and medulla of rats. These neurones are dispersed throughout the PVN and are often found near neurones antidromically invaded only from the pituitary salk. In addition, a small...

journal_title：Neuroscience letters

authors： Zerihun L,Harris M

更新日期：1981-05-06 00:00:00