Temporal order judgments for audiovisual targets embedded in unimodal and bimodal distractor streams.

abstract：:Recent studies have shown that aging, psychiatric and neurologic diseases, and dopaminergic blockade all result in altered brain network efficiency. We investigated the efficiency of human brain functional networks as measured by fMRI in individuals with idiopathic Parkinson's disease (N=14) compared to healthy age-ma...

journal_title：Neuroscience letters

authors： Skidmore F,Korenkevych D,Liu Y,He G,Bullmore E,Pardalos PM

更新日期：2011-07-15 00:00:00

abstract：:Neuraxial analgesia is often provided using a mixture of local anesthetics and opioids. This combination of agents provides better pain relief and is generally associated with fewer side effects than when either drug is given alone. Local anesthetics have been shown to alter signaling of other G protein-coupled recept...

journal_title：Neuroscience letters

authors： Komai H,McDowell TS

更新日期：2007-05-18 00:00:00

abstract：:Previous studies from our team have shown that a 12 month ethanol administration induced deficits in a sequential alternation task, whereas a 6 month treatment had no effects. We have already shown that the 12 month treatment induced deficits both in diencephalic and hippocampal structures, whereas the 6 month treatme...

journal_title：Neuroscience letters

authors： Beracochea D,Jaffard R

更新日期：1991-12-16 00:00:00

abstract：:Physiological and histochemical studies have clearly demonstrated the control and innervation of the sympathetic nerve on the splanchnic veins. However, the origins of postganglionic fibers remain to be determined. In this study, we used the retrograde transport of horseradish peroxidase (HRP) technique to trace the o...

journal_title：Neuroscience letters

authors： Chen HI,Kang BH,Wang JY,Tseng YL

更新日期：1994-05-23 00:00:00

abstract：:To study the spatial frequency (SF) effects on cortical face processing, we recorded magnetoencephalographic responses in seven healthy subjects to upright and inverted human faces. Four face types were used, including original (broad-band SF, BSF), low SF (LSF, <5 cycles/face), middle SF (MSF, 5-15 cycles/face), and ...

journal_title：Neuroscience letters

authors： Hsiao FJ,Hsieh JC,Lin YY,Chang Y

更新日期：2005-05-20 00:00:00

abstract：:Adenosine has been implicated in the regulation of rapid eye movement sleep (REMS). In an attempt to understand the mechanism of production of adenosine in relation to REMS it was hypothesized that should it be involved in REMS, the latter's deprivation is likely to affect its synthetic machinery. Hence, male albino r...

journal_title：Neuroscience letters

authors： Thakkar M,Mallick BN

更新日期：1996-03-15 00:00:00

abstract：:Pain is a complex and subjective experience that involves not only the transduction of noxious stimuli by nociceptive fibers, but also the cognitive and emotional processing by the brain. Previous studies on the transmission of nociception suggest that the activation of mesolimbic dopamine (DA) system plays an importa...

journal_title：Neuroscience letters

authors： Zhu J,Chen Y,Lai J,Dang Y,Yan C,Xu M,Chen T

更新日期：2010-06-25 00:00:00

abstract：:The distribution of mRNA coding for a pituitary thyrotropin releasing-hormone (TRH) receptor was examined on sections of spinal cord and lower brainstem of rat using in situ hybridization. Hybridization signals were observed over large neurons in the ventral horn in cervical, thoracic, and lumbar segments of spinal co...

journal_title：Neuroscience letters

authors： Wu W,Elde R,Wessendorf MW,Hökfelt T

更新日期：1992-08-17 00:00:00

abstract：:The objective of the present study was to characterize the trkB receptor immunoreactive (-ir) cells in the intermediolateral cell column (IML) of the upper thoracic spinal cord. Small trkB-ir cells (area=56.1+/-4.4 microm(2)) observed in the IML showed characteristics of oligodendrocytes and were frequently observed i...

journal_title：Neuroscience letters

authors： McCartney AM,Abejuela VL,Isaacson LG

更新日期：2008-08-01 00:00:00

abstract：:Activated microglia surround degenerating substantia nigra neurons in Parkinson's disease (PD). Such microglia produce high levels of interleukin-1 beta (IL-1 beta) and interleukin-1 alpha (IL-1 alpha). T and C alleles exist for the IL-1 beta-511 regulatory region as well as for the IL-1 alpha-889 regulatory region. T...

journal_title：Neuroscience letters

authors： McGeer PL,Yasojima K,McGeer EG

更新日期：2002-06-21 00:00:00

abstract：:The blood-brain barrier (BBB) maintains the homeostasis between the central nervous system and the blood circulation. One of the main efflux transporter proteins at the BBB is P-glycoprotein (P-gP) also known as ABCB1 or MDR1. Due to the important role of P-gP for the transport barrier function of the BBB, the presenc...

journal_title：Neuroscience letters

authors： Neuhaus W,Stessl M,Strizsik E,Bennani-Baiti B,Wirth M,Toegel S,Modha M,Winkler J,Gabor F,Viernstein H,Noe CR

更新日期：2010-01-22 00:00:00

abstract：:Gangliosides isolated from the brain of patients with Creutzfelt-Jakob (C-J) disease were analyzed. The ganglioside current was abnormally low, and the percentage distributions of individual gangliosides and the long-chain base compositions were abnormal. The C20-sphingosine contents of all the ganglioside fractions w...

journal_title：Neuroscience letters

authors： Tamai Y,Ohtani Y,Miura S,Narita Y,Iwata T,Kaiya H,Namba M

更新日期：1979-01-01 00:00:00

abstract：:Due to the hypothetical role of ovarian hormones, estrogen and progesterone, in cocaine-induced behavioral activity and self-administration, this study investigated the effects of cocaine, estrogen, and progesterone administration on monoamine levels in the medial prefrontal cortex of ovariectomized hormone-treated ra...

journal_title：Neuroscience letters

authors： Perrotti LI,Beck KD,Luine VN,Quiñones V

更新日期：2000-09-22 00:00:00

abstract：:The binding and pharmacological characteristics of [125I]iodomelatonin binding sites in human fetal brain membrane preparations were determined. Membrane preparations of the whole brain revealed a equilibrium binding constant (Kd) of 17.5 pmol/l with a total number of binding sites (Bmax) at 0.8 fmol/mg protein. Among...

journal_title：Neuroscience letters

authors： Yuan H,Lu Y,Pang SF

更新日期：1991-09-16 00:00:00

abstract：:In striatal neurons in primary culture quisqualate potently stimulated the formation of inositol phosphates via a metabotropic receptor we recently termed Qp in order to distinguish it from the classical ionotropic quisqualate receptor termed Qi. Here we show that 10 microM of quisqualate activated in a rapid and tran...

journal_title：Neuroscience letters

authors： Manzoni OJ,Finiels-Marlier F,Sassetti I,Blockaert J,le Peuch C,Sladeczek FA

更新日期：1990-02-05 00:00:00

abstract：:A major goal in the study of motor learning is to improve the extent to which subjects adapt their movements in response to errors. Recent attention has focused on the gradual-adaptation paradigm, in which an adaptive stimulus is introduced incrementally, rather than all at once as in conventional adaptation paradigms...

journal_title：Neuroscience letters

authors： Wong AL,Shelhamer M

更新日期：2011-08-18 00:00:00

abstract：:The effects of i.v. administration of a nitric oxide (NO) synthase inhibitor, L-NG-nitroarginine (L-NOArg), on the increase in cerebral cortical blood flow (cortical BF), following either electrical stimulation of the nucleus basalis of Meynert (NBM), whose cholinergic fibers project to the cortex, or hypercapnia with...

journal_title：Neuroscience letters

authors： Adachi T,Inanami O,Sato A

更新日期：1992-05-25 00:00:00

abstract：:To test the hypothesis that the expression of specific proteins on peripheral terminals of primary afferents can be attenuated by intrathecal administration of antisense oligodeoxynucleotides (ODNs), we administered ODNs antisense to the mu-opioid receptor to male Sprague-Dawley rats via chronically implanted intrathe...

journal_title：Neuroscience letters

authors： Khasar SG,Gold MS,Dastmalchi S,Levine JD

更新日期：1996-10-25 00:00:00

abstract：:The central nervous system preplans postural responses to successfully perform complex multi-joint movements. These responses have been termed anticipatory postural adjustments (APAs), and they constitute a general type of response to stabilize posture prior to movement initiation. APA sequences are elicited with shor...

journal_title：Neuroscience letters

authors： Kennefick M,Wright AD,Smirl JD,van Donkelaar P

更新日期：2018-09-25 00:00:00

abstract：:Presenilin-1 (PSEN1) mutations I143T and G384A give rise to severe early onset Alzheimers's disease in two extensively studied Belgian families, AD/A and AD/B. In this study we investigated the influence of the I143T and G384A mutations on PSEN1 proteolytic processing. Hereto we analyzed PSEN1 processing in lymphoblas...

journal_title：Neuroscience letters

authors： Vanderhoeven I,Cras P,Martin JJ,Van Broeckhoven C,De Jonghe C

更新日期：1999-10-29 00:00:00

abstract：:In gastropods, the interneuronal messenger, nitric oxide (NO), modulates spike frequency and synaptic transmission. We have characterized the effect of NO on ion currents underlying neuronal excitability, using current-clamp and two-electrode voltage-clamp techniques. Identified neurons of the pulmonate snail, Helix p...

journal_title：Neuroscience letters

authors： Zsombok A,Schrofner S,Hermann A,Kerschbaum HH

更新日期：2000-12-08 00:00:00

abstract：:It has been proposed that the perception of a coherent image necessitates two processes, that is, an ensemble of neurons which synchronizes discharges of individual cells and stimulus-specific gamma-band (gamma) neuronal oscillations which may serve as carrier signals for a temporal code. We tested the hypothesis that...

journal_title：Neuroscience letters

authors： Shumikhina S,Molotchnikoff S

更新日期：1999-09-10 00:00:00

abstract：:Interleukin-6 (IL-6) has been shown to have potent neurotrophic activity on peripheral and central neurons in vitro. However, it remains to be determined whether or not IL-6 rescues hippocampal CA1 neurons from lethal ischemia and prevents ischemia-induced learning disability. In the present in vivo study, we infused ...

journal_title：Neuroscience letters

authors： Matsuda S,Wen TC,Morita F,Otsuka H,Igase K,Yoshimura H,Sakanaka M

更新日期：1996-02-02 00:00:00

abstract：:Calcium antagonists inhibit both the Ca2(+)-dependent and -independent release of endogenous glutamate from intact synaptosomes. In the present study, the inhibitory potency of several different classes of calcium antagonists were determined under conditions that control for an effect of these compounds on the Ca2(+)-...

journal_title：Neuroscience letters

authors： Terrian DM,Dorman RV,Gannon RL

更新日期：1990-11-13 00:00:00

abstract：:The expression of dystrophin-protein 71 (Dp71) was investigated during nerve growth factor (NGF) induced differentiation of PC12 cells. A semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) assay was designed to measure Dp71 mRNA, whereas the Dp71 protein amount was evaluated by immunoblot analy...

journal_title：Neuroscience letters

authors： Cisneros B,Rendon A,Genty V,Aranda G,Marquez F,Mornet D,Montañez C

更新日期：1996-08-02 00:00:00

abstract：:Brain pericytes are involved in neurovascular dysfunction, neurodegeneration and/or neuroinflammation. In the present study, we focused on the proinflammatory properties of brain pericytes to understand their participation in the induction of inflammation at the neurovascular unit (NVU). The NVU comprises different ce...

journal_title：Neuroscience letters

authors： Matsumoto J,Takata F,Machida T,Takahashi H,Soejima Y,Funakoshi M,Futagami K,Yamauchi A,Dohgu S,Kataoka Y

更新日期：2014-08-22 00:00:00

abstract：:Benzodiazepine (BZ) recognition sites of the 'peripheral' type were localized autoradiographically in human postmortem brain and kidney using [3H]Ro 5-4864. These sites presented a relatively homogeneous distribution. Areas such as the ependyma, choroid plexus and olfactory bulb, which in the rat are very rich in thes...

journal_title：Neuroscience letters

authors： Pazos A,Cymerman U,Probst A,Palacios JM

更新日期：1986-05-15 00:00:00

abstract：:Alzheimer's disease is correlated with neuronal degeneration and loss of neuronal precursors in different parts of the brain. It has been found disturbance in the homeostasis neural stem cells (NSCs) can cause neurodegeneration. Morphine, an analgesic agent, can disrupt the dynamic and normal state of NSCs. However, m...

journal_title：Neuroscience letters

authors： Salarinasab S,Nourazarian A,Nikanfar M,Abdyazdani N,Kazemi M,Feizy N,Rahbarghazi R

更新日期：2017-11-01 00:00:00

abstract：:Neurons of the lateral olivocochlear (LOC) system project from the auditory brainstem to the cochlea, where they synapse on radial dendrites of auditory nerve fibers. Selective LOC disruption depresses sound-evoked auditory nerve activity in the guinea pig, but enhances it in the mouse. Here, LOC disruption depressed ...

journal_title：Neuroscience letters

authors： Le Prell CG,Dolan DF,Hughes LF,Altschuler RA,Shore SE,Bledsoe SC Jr

更新日期：2014-10-17 00:00:00

abstract：:Cerebellar Purkinje cells differentiate the most elaborate dendritic trees among neurons in the brain and constitute the principal part of cerebellar neuronal circuitry. In the present study, we examined the role of the GluA2 subunit of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate recepto...

journal_title：Neuroscience letters

authors： Tanaka M,Senda T,Hirashima N

更新日期：2017-09-14 00:00:00