Disruption of lateral olivocochlear neurons with a dopaminergic neurotoxin depresses spontaneous auditory nerve activity.

abstract：:Circadian firing rhythms of cultured rat suprachiasmatic nucleus were measured simultaneously from 4-8 neurons by using a multi-electrode dish and neuronal interactions were examined by a cross-correlation analysis of spontaneous action potentials. Functional connections were detected in the neuron pairs showing synch...

journal_title：Neuroscience letters

authors： Honma S,Shirakawa T,Nakamura W,Honma K

更新日期：2000-11-17 00:00:00

abstract：:Supra-threshold responses of neurons in the primary auditory cortex of the macaque monkey are so complex that the characteristic frequency cannot be determined. By statistical analyses based on analysis of variance and principal component analysis, we demonstrated that the similarity of neurons from penetration perpen...

journal_title：Neuroscience letters

authors： Takahashi T

更新日期：1995-02-24 00:00:00

abstract：:Transgenic mice (Tg2576) that express the Swedish double mutation of human amyloid precursor protein and develop Alzheimer-like beta-amyloid deposits in the aged brain, were used to study the effect of beta-amyloid deposition on expression of both neuronal (nNOS) and inducible nitric oxide synthase (iNOS) in cells sur...

journal_title：Neuroscience letters

authors： Hartlage-Rübsamen M,Apelt J,Schliebs R

更新日期：2001-04-20 00:00:00

abstract：:This investigation was designed to determine the responses of neurons in the posterior group of nuclei (PO) to tooth pulp stimulation. Eighteen tooth pulp-driven (TPD) neurons were recorded in 9 cats anesthetized with nitrous oxide and halothane, 14 of them in the medial part (POM) and the remainder in the lateral par...

journal_title：Neuroscience letters

authors： Matsumoto N,Sato T,Sawano H,Tochinai A,Suzuki TA

更新日期：1988-11-11 00:00:00

abstract：:Intracellular recordings were made from neurons in bullfrog sympathetic ganglia. Orthodromic, intracellular and antidromic stimulations evoked recurrent depolarizing responses accompanied by a spontaneous firing of the action potential in type 2 neurons. The depolarizing response elicited by intracellular and antidrom...

journal_title：Neuroscience letters

authors： Nishimura T,Akasu T

更新日期：1988-04-12 00:00:00

abstract：:Alternative cleavage of the amyloid precursor protein (APP) results in generation and secretion of both soluble APP (sAPP) and beta-amyloid (Abeta). Abeta is the main component of the amyloid depositions in the brains of Alzheimer's disease (AD) patients. Using Western blotting, we compared the levels of alpha-secreta...

journal_title：Neuroscience letters

authors： Sennvik K,Fastbom J,Blomberg M,Wahlund LO,Winblad B,Benedikz E

更新日期：2000-01-14 00:00:00

abstract：:Single electrode voltage-clamp recording from CA3 neurons in guinea pig hippocampal slices was applied to study effects of a new GABAB antagonist, CGP 55845A, on (-)baclofen (IBac)- or gamma-aminobutyric acid (IGABA)-induced potassium (K)-currents and on inhibitory postsynaptic K-currents (K-IPSCs) recorded in the pre...

journal_title：Neuroscience letters

authors： Jarolimek W,Demmelhuber J,Bijak M,Misgeld U

更新日期：1993-05-14 00:00:00

abstract：:Oligodendrocytes in different central nervous system regions have dissimilar morphologies. In order to find out if immature oligodendrocytes develop different phenotypes spontaneously, neonatal spinal and cerebral rat oligodendrocytes were cultured in vitro in the absence of neurons. The results show that spinal oligo...

journal_title：Neuroscience letters

authors： Bjartmar C

更新日期：1998-05-15 00:00:00

abstract：:The effect of dopamine on the 3',5'-cyclic adenosine monophosphate (cAMP) generating system of membrane particles of rat prostate gland was studied. Dopamine increased the concentration of cAMP in a dose-dependent manner. The selective D1 receptor inhibitor SCH 23390 caused a decrease in dopamine-elicited cAMP levels....

journal_title：Neuroscience letters

authors： Amenta D,Cavallotti C,Amenta F

更新日期：1987-06-01 00:00:00

abstract：:A previous study has shown that inflammation of the gastrocnemius-soleus muscle in rats leads to an increase in excitability of dorsal horn neurones particularly in the spinal segment L3. Here, we have blocked the nitric oxide synthase (NOS) in L3 by spinal cord superfusion with NG-monomethyl-L-arginine (L-NMMA) to fi...

journal_title：Neuroscience letters

authors： Hoheisel U,Sander B,Mense S

更新日期：1995-03-24 00:00:00

abstract：:A high expression of PrP(C) in cells is one factor that increases the risk of conversion to the misfolded, disease-associated form (PrP(Sc)) characteristic of transmissible spongiform encephalopathies. Thus, developing a method to control the level of PrP(C) expression in cells could be one way to delay or prevent the...

journal_title：Neuroscience letters

authors： Zawlik I,Witusik M,Hulas-Bigoszewska K,Piaskowski S,Szybka M,Golanska E,Liberski PP,Rieske P

更新日期：2006-05-29 00:00:00

abstract：:Enterovirus infections of the central nervous system (CNS) are common and important causes of morbidity in immunocompromised children and adults. In this study we identify and characterize coxsackievirus B4-induced neuronal death. To investigate the CNS pathophysiology resulting from this viral infection, cultured rat...

journal_title：Neuroscience letters

authors： Joo CH,Kim YK,Lee H,Hong H,Yoon SY,Kim D

更新日期：2002-07-05 00:00:00

abstract：:Stereotaxic injections of ibotenic acid (IBO) and kainic acid (KA) into either the dorsal hippocampus or the lateral cerebroventricle were performed in order to determine the relative potencies of the drugs and the vulnerability of different hippocampal cell types to their neurotoxic action, IBO was found to be approx...

journal_title：Neuroscience letters

authors： Köhler C,Schwarcz R,Fuxe K

更新日期：1979-12-01 00:00:00

abstract：:FOXP2, the first gene known to be involved in the development of speech and language, can be considered to be, a priori, a candidate gene in schizophrenia, given the mounting evidence that the underlying core deficit in this disease could be a failure of structures relevant to normal language processing. To investigat...

journal_title：Neuroscience letters

authors： Španiel F,Horáček J,Tintěra J,Ibrahim I,Novák T,Čermák J,Klírová M,Höschl C

更新日期：2011-04-15 00:00:00

abstract：:There is considerable evidence linking both genotype and coagulopathy to vascular complications of traumatic brain injury (TBI) and other cerebral insults. The authors explored a possible connection between the apolipoprotein E (Apo E) genotype, coagulopathy and intravascular microthombosis (IMT) in TBI. The predicted...

journal_title：Neuroscience letters

authors： Stein SC,Graham DI,Chen XH,Dunn L,Smith DH

更新日期：2005-10-14 00:00:00

abstract：:In an in vitro preparation of the crayfish thoracic locomotor system, paired intracellular recordings were performed from antagonistic depressor (Dep) and levator (Lev) motoneurons (MNs) that control the second joint of walking legs. Connections between these two groups of MNs consist mainly of inhibitory connections ...

journal_title：Neuroscience letters

authors： Pearlstein E,Clarac F,Cattaert D

更新日期：1998-01-23 00:00:00

abstract：:Hemispheric asymmetries in spatial processing are generally considered to be responsible for the shorter reaction time (RT) of the left hand classically observed for right-handers when pointing at targets. Surprisingly, despite the special role which the right cerebral hemisphere is known to play in visual attention, ...

journal_title：Neuroscience letters

authors： Barthelemy S,Boulinguez P

更新日期：2001-11-23 00:00:00

abstract：:Using in vivo voltammetric detection of nitric oxide (NO) a previous study demonstrated an increased NO release at the lumbar dorsal horn level of the spinal cord by peripheral inflammatory processes in decerebrated-spinalized rats. This study concerns the effects of acute peripheral stimulations. Gentle non-noxious o...

journal_title：Neuroscience letters

authors： Rivot JP,Montagne-Clavel J,Besson JM

更新日期：2002-03-01 00:00:00

abstract：:The actions of agonists and antagonists of excitatory amino acid receptors were studied in the isolated ileal longitudinal muscle-myenteric plexus preparation of the guinea pig incubated 'in vitro', by recording the contraction of the longitudinal muscle. L-Glutamate, L-aspartate, quinolinate and N-methyl-D-aspartate ...

journal_title：Neuroscience letters

authors： Moroni F,Luzzi S,Franchi-Micheli S,Zilletti L

更新日期：1986-07-11 00:00:00

abstract：:Although the therapeutic use of microglia has received some attention for the treatment of brain diseases, few non-invasive techniques exist for monitoring the cells after administration. Here, we present a technique using magnetic resonance imaging (MRI) to track microglia injected intra-cardially. We labeled microgl...

journal_title：Neuroscience letters

authors： Song Y,Morikawa S,Morita M,Inubushi T,Takada T,Torii R,Tooyama I

更新日期：2006-02-27 00:00:00

abstract：:The possible voltage-dependence of the dopamine transporter (DAT) was investigated using electrophysiological and electrochemical recordings in rat brain slices containing the substantia nigra (SN). Whole-cell patch clamp recordings of DA neurons, revealed that addition of 15 mM KCl rapidly depolarized the membrane po...

journal_title：Neuroscience letters

authors： Hoffman AF,Zahniser NR,Lupica CR,Gerhardt GA

更新日期：1999-01-29 00:00:00

abstract：:Mutations in the hairless (hr) gene of mice result in hair follicle and other epithelial defects. The hr gene is expressed at high levels in the brain where it probably participates in the survival and maintenance of some neuronal populations, but whether it also supports glial populations of the central nervous syste...

journal_title：Neuroscience letters

authors： San Jose I,García-Atares N,Pelaez B,Cabo R,Esteban I,Vega JA,Represa J

更新日期：2001-08-24 00:00:00

abstract：:Nucleotide-binding domain and leucine-rich-repeat-containing family member X1 (NLRX1) is a cytoplasmic pattern recognition receptor that is predominantly located in mitochondria, which is tightly related to mitochondrial damage, reactive oxygen species (ROS) production, inflammation and apoptosis. The present study wa...

journal_title：Neuroscience letters

authors： Yang Q,Sun G,Cao Z,Yin H,Qi Q,Wang J,Liu W,Bai X,Wang H,Li J

更新日期：2016-03-11 00:00:00

abstract：:We have investigated the effect of ethanol upon vasopressin (AVP) content in brain and upon in-vitro release of AVP from the rat median eminence. In-vitro ethanol concentrations (5-25 mM), comparable to behaviorally relevant blood ethanol levels, induce a substantial inhibition of AVP release from the median eminence,...

journal_title：Neuroscience letters

authors： Brinton RE,Gruener R,Deshmukh P,Yamamura HI

更新日期：1986-06-18 00:00:00

abstract：:Damaged axons in the adult central nervous system (CNS) fail to regenerate spontaneously due to several intrinsic and extrinsic factors that inhibit axon elongation. An extrinsic inhibitory factor, repulsive guidance molecule-a (RGMa), is upregulated around spinal cord lesion sites. Inhibition of RGMa using an antibod...

journal_title：Neuroscience letters

authors： Nakanishi T,Fujita Y,Tanaka T,Yamashita T

更新日期：2019-09-14 00:00:00

abstract：:Recent imaging studies have reported the projection of semicircular canal signals onto wide regions of the cerebral cortex but little is known about otolith projections onto the cerebral cortex. We used functional magnetic resonance imaging (fMRI) to investigate the activation of the cortex by loud clicks that selecti...

journal_title：Neuroscience letters

authors： Miyamoto T,Fukushima K,Takada T,de Waele C,Vidal PP

更新日期：2007-08-09 00:00:00

abstract：:The interaction of NMDA receptor (NMDAR) activation and other mechanisms regulating neuronal excitability have not been thoroughly described. While excess activation of NMDARs results in excitotoxicity, partial activation of NMDARs by d-cycloserine (DCS) is nootropic, enhancing both acquisition and extinction of memor...

journal_title：Neuroscience letters

authors： Donzis EJ,Thompson LT

更新日期：2014-06-13 00:00:00

abstract：:Substance P caused a depolarization of cultured spinal neurones which was often accompanied by a decrease in membrane conductance. The peptide usually had no effect on the membrane potential and resistance of glial cells. In contrast to the depolarization by glutamate, which is associated with an influx of Na+ and an ...

journal_title：Neuroscience letters

authors： Hösli L,Hösli E,Zehntner C,Landolt H

更新日期：1981-07-02 00:00:00

abstract：:The facial nucleus (FN) has been known as a motor nucleus to control the activity of the facial skeletal muscles by its efferent somatic motoneurons. Much less, however, is known about the non-motor control functions of its interneurons. The present study was designed to investigate if the interneurons of the FN parti...

journal_title：Neuroscience letters

authors： Zhang C,Yan H,Li C,Zheng Y

更新日期：2004-09-09 00:00:00

abstract：:Dorsal root potentials (DRPs) and dorsal cord potentials (DCPs) were recorded from the lumbar spinal cord in anaesthetised rats. With the spinal cord intact, low-voltage low-frequency spontaneous DRPs were recorded in synchrony on all lumbar dorsal roots. When the cord was cut at T12, spontaneous large-voltage approxi...

journal_title：Neuroscience letters

authors： Lidierth M,Wall PD

更新日期：1996-12-06 00:00:00