Propranolol blocks recurrent synaptic activation in paravertebral sympathetic ganglia of bullfrogs.

abstract：:The structure of CACNA1G, the gene encoding alpha1G, a human brain T Ca2+ channel alpha1 subunit, was determined by comparison of polymerase chain reaction-amplified brain cDNA and genomic sequences. The gene consists of at least 38 exons, two of them newly-identified, spanning at least 66490 basepairs of chromosome 1...

journal_title：Neuroscience letters

authors： Mittman S,Guo J,Agnew WS

更新日期：1999-10-29 00:00:00

abstract：:Comparable to the anti-craving compound acamprosate, caroverine reduces alcohol withdrawal symptoms by an antagonism at ionotropic glutamate receptors and a blockade of calcium channels. The present study examines the effect of caroverine in a craving model, in which acamprosate has proved effective before. A place av...

journal_title：Neuroscience letters

authors： Kratzer U,Schmidt WJ

更新日期：2003-10-02 00:00:00

abstract：:Genetic polymorphism has been reported in the 3'-untranslated region (3'-UTR) of the human dopamine transporter (DAT) gene and the variable number of tandem repeat (VNTR) polymorphism has been proposed to be associated with normal personal traits or psychoneurological disorders. To assess the variation of this region ...

journal_title：Neuroscience letters

authors： Inoue-Murayama M,Adachi S,Mishima N,Mitani H,Takenaka O,Terao K,Hayasaka I,Ito S,Murayama Y

更新日期：2002-12-16 00:00:00

abstract：:The potassium-chloride cotransporter 2 (KCC2)-dependent intracellular chloride level determines whether neurons respond to GABA and/or glycine by depolarization or hyperpolarization. However, still unknown is the role of KCC2-dependent chloride homeostasis in regulating the spontaneous activity of neuronal circuits vi...

journal_title：Neuroscience letters

authors： Wang W,Xu TL

更新日期：2006-10-02 00:00:00

abstract：:We wanted to verify the magnetic resonance imaging (MRI) abnormalities that occur in the central nervous system (CNS) of cobalamin-deficient (Cbl-D) rats. The rats were made Cbl-D by means of total gastrectomy or feeding a Cbl-D diet. MR images of the cervical tract of the vertebral canal were recorded using a vertica...

journal_title：Neuroscience letters

authors： Veber D,Mutti E,Sironi L,Guerrini U,Gianazza E,Scalabrino G

更新日期：2008-08-08 00:00:00

abstract：:Our aim was to investigate the neuromodulatory role of diadenosine tetraphosphate (Ap(4)A). Ap(4)A-binding sites were detected in striatum and hippocampus membranes using [(35)S]-ADP beta S as radioligand and Ap(4)A and epsilon-(Ap(4)A), di-ethenoadenosine tetraphosphate, as displacers. Effects of epsilon-(Ap(4)A) on ...

journal_title：Neuroscience letters

authors： Oaknin S,Rodríguez-Ferrer CR,Aguilar JS,Ramos A,Rotllán P

更新日期：2001-08-31 00:00:00

abstract：:Several studies reported that peripheral administration of bombesin (BN) and gastrin-releasing peptide (GRP) improved some forms of memory performance. In the present study, we examined the role of endogenous BN-like peptide(s) for the acquisition of inhibitory avoidance learning in mice using BN-like peptide receptor...

journal_title：Neuroscience letters

authors： Santo-Yamada Y,Yamada K,Wada E,Goto Y,Wada K

更新日期：2003-04-03 00:00:00

abstract：:The Amphibalanus amphitrite barnacle is a sessile marine crustacean and a major constituent of benthic as well as intertidal communities. A. amphitrite is also an important component of biofouling on artificial substrates. The role of nitric oxide (NO) was recently observed in the settlement of this species. In this w...

journal_title：Neuroscience letters

authors： Gallus L,Ferrando S,Gambardella C,Faimali M,Piazza V,Masini MA

更新日期：2013-10-25 00:00:00

abstract：:Gastrin-releasing peptide (GRP) was demonstrated by immunohistochemistry and high-performance liquid chromatography to be present in the great majority of neurons in the geniculate ganglion of rat and man. This was in contrast to findings in the sphenopalatine ganglion of rat, where only little GRP was found, and in t...

journal_title：Neuroscience letters

authors： Hardebo JE,Suzuki N,Ekman R

更新日期：1992-05-25 00:00:00

abstract：:Eight male rats were deprived of rapid eye movement (REM) sleep for 6 days by means of a cuff pedestal which makes it possible to use the animal as its own control. In order to obtain access to food, the rat had to jump from its pedestal to a strip of wire mesh suspended from the ceiling of the deprivation chamber. Th...

journal_title：Neuroscience letters

authors： Elomaa E,Johansson GG

更新日期：1986-01-02 00:00:00

abstract：:Recently, we demonstrated that dimeric apocynin prevented loss of motor function in the leucine-rich repeat kinase 2 (LRRK2(R1441G)) transgenic (tg) mouse (treated with 200mg/kg, three times per week) [B.P. Dranka et al., Neurosci. Lett. 549 (2013) 57-62]. Here we extend those studies by treating LRRK2(R1441G) mice wi...

journal_title：Neuroscience letters

authors： Dranka BP,Gifford A,McAllister D,Zielonka J,Joseph J,O'Hara CL,Stucky CL,Kanthasamy AG,Kalyanaraman B

更新日期：2014-11-07 00:00:00

abstract：:This study in lampreys (Lampetra fluviatilis L.) is concerned with the phylogenetic age of the suprachiasmatic nucleus of the hypothalamus which in mammals receives input from the retinohypothalamic tract and acts as circadian pacemaker. Tracing experiments with the fluorescent dye DiI demonstrated a retinohypothalami...

journal_title：Neuroscience letters

authors： Weigle C,Wicht H,Korf HW

更新日期：1996-10-18 00:00:00

abstract：:Protein kinase C (PKC) pathway plays important roles in different phenomena in nervous system development. Our previous data demonstrated that phorbol 12-myristate 13-acetate (PMA) treatment, a PKC activator, for 48 h decreases retinal cells proliferation by a mechanism mediated by muscarinic receptor activation, invo...

journal_title：Neuroscience letters

authors： Braga LE,Granja MG,da Silva GM,Giestal-de-Araujo E,dos Santos AA

更新日期：2013-08-29 00:00:00

abstract：:Very recent studies in adult gerbils and rats have shown that exposure to sublethal ischemia can confer neuroprotection from subsequent lethal ischemic episodes. To determine if a similar phenomenon can be elicited during the perinatal period, we have developed a preconditioning regimen that involves exposure to normo...

journal_title：Neuroscience letters

authors： Gidday JM,Fitzgibbons JC,Shah AR,Park TS

更新日期：1994-02-28 00:00:00

abstract：:We immunohistochemically investigated the degeneration processes of the nigro-striatal and nigro-amygdaloid pathways and the relationship between the loss of dopaminergic neurons and Lewy bodies (LB) formation in the substantia nigra using 15 autopsied cases of dementia with Lewy bodies (DLB). The number of tyrosine h...

journal_title：Neuroscience letters

authors： Iseki E,Marui W,Yamamoto R,Togo T,Katsuse O,Kato M,Iwatsubo T,Kosaka K,Arai H

更新日期：2005-05-20 00:00:00

abstract：:Several studies have suggested an important role for brain-derived neurotrophic factor (BDNF) in the pathophysiology and therapeutics of bipolar disorder (BPD). The mechanisms underlying the therapeutic effects of lithium in BPD seem to involve a direct regulation of neurotrophic cascades. However, no clinical study e...

journal_title：Neuroscience letters

authors： de Sousa RT,van de Bilt MT,Diniz BS,Ladeira RB,Portela LV,Souza DO,Forlenza OV,Gattaz WF,Machado-Vieira R

更新日期：2011-04-20 00:00:00

abstract：:Intracellular injection of the calcium chelator BAPTA into postinspiratory (PI) and late inspiratory neurones (late-I) of the ventral respiratory group of anaesthetised cat was performed to study the role of intracellular free calcium in patterning the activity of neurones controlling termination of inspiration. BAPTA...

journal_title：Neuroscience letters

authors： Pierrefiche O,Champagnat J,Richter DW

更新日期：1995-01-23 00:00:00

abstract：:We have recently documented the presence of cholinergic neurons containing monoamine oxidase (MAO)-B activity in the striatum of C57BL/6 mouse. In the present study, we have mapped the topographical distributions of MAO-containing neurons in the mouse striatum. Positive neurons were located in the striatum of the enti...

journal_title：Neuroscience letters

authors： Nakamura S,Akiguchi I,Kimura J

更新日期：1995-01-16 00:00:00

abstract：:Studies involving receptor protection have been used to define the functional involvement of specific receptor subtypes in tissues expressing multiple receptor subtypes. Previous functional studies from our laboratory demonstrate the feasibility of this approach when applied to neuronal tissues expressing multiple nic...

journal_title：Neuroscience letters

authors： Free RB,Kaser DJ,Boyd RT,McKay DB

更新日期：2006-01-09 00:00:00

abstract：:To examine the effect of apolipoprotein E (ApoE) 4 on the progression of Alzheimer's disease (AD), the clinical course of 33 AD patients (17 cases with ApoE epsilon4 and 16 cases without ApoE epsilon4) was evaluated with the mini-mental state examination (MMSE) and cerebrospinal fluid (CSF) biological markers. The dec...

journal_title：Neuroscience letters

authors： Kanai M,Shizuka M,Urakami K,Matsubara E,Harigaya Y,Okamoto K,Shoji M

更新日期：1999-05-21 00:00:00

abstract：:We have found an APOE epsilon 4 allelic frequency of 0.289 (95% CI 0.195-0.383) in Spanish AD patients (n = 88; average age = 71.2 +/- 9.37) and of 0.061 (95% CI 0.023-0.099) in age-matched controls (n = 147; average age = 71.5 +/- 10.29). Remarkably no ApoE 4/4 subjects were observed in any of the age-matched control...

journal_title：Neuroscience letters

authors： Adroer R,Santacruz P,Blesa R,López-Pousa S,Ascaso C,Oliva R

更新日期：1995-04-21 00:00:00

abstract：:This study investigated the effects of ketamine on fluoxetine-induced antidepressant behavior using the forced swimming test (FST) in mice. In order to understand the possible role of N-methyl-d-aspartate (NMDA) neurotransmission in the antidepressant effect of fluoxetine, different groups of mice (n=10) were administ...

journal_title：Neuroscience letters

authors： Owolabi RA,Akanmu MA,Adeyemi OI

更新日期：2014-04-30 00:00:00

abstract：:Inflammation is an important contributor to the development of Alzheimer's disease (AD). Anti-inflammatory medication may offer promising treatment for AD. Hydroxy-safflor yellow A (HSYA), a chemical component of the safflower yellow pigments, has been reported to exert potent immunosuppressive effects. This study exa...

journal_title：Neuroscience letters

authors： Zhang Z,Wu Z,Zhu X,Hui X,Pan J,Xu Y

更新日期：2014-03-06 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH) metabolism in NIH:N mouse cerebral cortex and spinal cord was studied with high pressure liquid chromatography. Degradation of added TRH was significantly (P less than 0.001) slower in the spinal cord (2.19 +/- 0.46%/min) than in the cerebral cortex (7.54 +/- 0.31%/min). Bacitracin,...

journal_title：Neuroscience letters

authors： Schwartz TM,Turner JG,Brooks BR

更新日期：1986-11-11 00:00:00

abstract：:Spirulina maxima is a blue-green micro alga that contains abundant amounts of proteins (60-70%), vitamins, chlorophyll a, and C-phycocyanin (C-PC). It has been shown to reduce oxidative stress, and prevent diabetes and non-alcoholic fatty liver disease. However, it is unclear whether Spirulina maxima 70% ethanol extra...

journal_title：Neuroscience letters

authors： Koh EJ,Kim KJ,Choi J,Kang DH,Lee BY

更新日期：2018-04-23 00:00:00

abstract：:In our horseradish peroxidase (HRP) study of the afferents to the medullary raphe nuclei in the cat, HRP uptake by damaged axons en route to the inferior olive (IO) was thought to be responsible for retrograde labelling of specific midbrain nuclei. To control for such indirect labelling, HRP was injected iontophoretic...

journal_title：Neuroscience letters

authors： Abols IA,Basbaum AI

更新日期：1979-07-01 00:00:00

abstract：:Responses of single neurones to vibrissal stimulation and to the iontophoretically applied putative neurotransmitters, L-glutamate and L-aspartate, were recorded in the trigeminal nucleus caudalis of the rat. Vibrissal responses were unaffected by the specific N-methyl-D-aspartate receptor antagonist, D-alpha-aminoadi...

journal_title：Neuroscience letters

authors： Salt TE,Hill RG

更新日期：1981-03-10 00:00:00

abstract：:The chitinase 3-like 1 (CHI3L1) gene, a cellular survival factor against several environmental and psychosocial stresses, has been sown to be more highly expressed in the hippocampus and prefrontal cortex of patients with schizophrenia than unaffected individuals. We recently reported a significant association between...

journal_title：Neuroscience letters

authors： Yamamori H,Hashimoto R,Ohi K,Yasuda Y,Fukumoto M,Kasahara E,Sekiyama A,Umeda-Yano S,Okada T,Iwase M,Kazui H,Ito A,Takeda M

更新日期：2012-04-04 00:00:00

abstract：:Zebra finches are ideal animals to investigate sex difference in songbirds. Only males can sing. The brain nuclei controlling song learning and production in males are considerably larger than in females. The robust nucleus of the arcopallium (RA) is a premotor nucleus, playing a key role in controlling singing. RA re...

journal_title：Neuroscience letters

authors： Wang S,Meng W,Liu S,Liao C,Huang Q,Li D

更新日期：2014-10-17 00:00:00

abstract：:The monoamine innervation of the organum vasculosum lamina terminalis (OVLT) was studied using fluorescence histochemistry and the autoradiographic tracing method. Fluorescence histochemistry demonstrates serotonin terminals in close proximity to the capillary plexus of the OVLT, in the same region where the apparent ...

journal_title：Neuroscience letters

authors： Moore RY

更新日期：1977-08-01 00:00:00