Effects of substance P on neurones and glial cells in cultured rat spinal cord.

Abstract:

:Substance P caused a depolarization of cultured spinal neurones which was often accompanied by a decrease in membrane conductance. The peptide usually had no effect on the membrane potential and resistance of glial cells. In contrast to the depolarization by glutamate, which is associated with an influx of Na+ and an efflux of K+, the action of substance P may be due to a decrease of the K+-conductance.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Hösli L,Hösli E,Zehntner C,Landolt H

doi

10.1016/0304-3940(81)90242-1

subject

Has Abstract

pub_date

1981-07-02 00:00:00

pages

165-8

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(81)90242-1

journal_volume

24

pub_type

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