Time-variant structure of auditory cortex of the macaque monkey.

Abstract:

:Supra-threshold responses of neurons in the primary auditory cortex of the macaque monkey are so complex that the characteristic frequency cannot be determined. By statistical analyses based on analysis of variance and principal component analysis, we demonstrated that the similarity of neurons from penetration perpendicular to the surface of the cortex decreases to such a level that they cannot be considered as a unit and that correlation among neurons from different cortical positions can be higher than that for neurons from penetration. This means that the frequency map is not evident for stimuli at supra-threshold. Moreover, we found that a single neuron utilizes different time segments to extract different physical aspects of stimuli. Our results indicate that encoding auditory information may involve other structures than the frequency map.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Takahashi T

doi

10.1016/0304-3940(95)11322-n

subject

Has Abstract

pub_date

1995-02-24 00:00:00

pages

1-4

issue

1

eissn

0304-3940

issn

1872-7972

pii

030439409511322N

journal_volume

187

pub_type

杂志文章
  • Immunohistochemical studies on synapse formation by embryonic cerebellar tissue transplanted into the cerebellum of the weaver mutant mouse.

    abstract::Normal cerebellar tissue, obtained from 15-day-old CBA/JNCij mouse embryos, was transplanted into the cerebellum of 4-week-old weaver mice. At the 6th week after the transplantation, the grafted tissue was distinguishable from the host cerebellum, developing a trilaminar organization. The formation of synapses by the ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(87)90437-x

    authors: Takayama H,Kohsaka S,Shinozaki T,Inoue H,Toya S,Ueda T,Tsukada Y

    更新日期:1987-08-31 00:00:00

  • The A140V mutation in the MECP2 gene is not a common etiological factor among Brazilian mentally retarded males.

    abstract::In mammals, methyl-CpG binding proteins play a significant role in the control of gene expression through their association with chromatin-remodeling complexes. Mutations in the gene coding for methyl-CpG-binding protein 2 (MECP2) cause Rett syndrome and have also been reported in a number of X-linked mental retardati...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.12.036

    authors: dos Santos JM,Abdalla CB,Campos M Jr,Santos-Rebouças CB,Pimentel MM

    更新日期:2005-04-29 00:00:00

  • Effect of SB-750364, a specific TRPV1 receptor antagonist, on injury-induced ectopic discharge in the lingual nerve.

    abstract::Abnormal neural activity generated at a site of nerve injury is thought to contribute to the development of dysaesthesia. Vanilloid receptor 1 (TRPV1), a transducer of noxious stimuli, may be involved in the initiation of this abnormal activity and could provide a useful therapeutic target. We investigated the effect ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.06.088

    authors: Biggs JE,Yates JM,Loescher AR,Clayton NM,Robinson PP,Boissonade FM

    更新日期:2008-09-26 00:00:00

  • Tryptophan hydroxylase mRNA levels are elevated by repeated immobilization stress in rat raphe nuclei but not in pineal gland.

    abstract::Repeated stress triggers a wide range of adaptive changes in the central nervous system including the elevation of serotonin (5-HT) metabolism and an increased susceptibility to affective disorders. To begin to examine whether these changes are mediated by alterations in gene expression for tryptophan hydroxylase (TPH...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00340-7

    authors: Chamas F,Serova L,Sabban EL

    更新日期:1999-06-04 00:00:00

  • Mitochondrial anomalies are associated with the induction of intrinsic cell death proteins-Bcl(2), Bax, cytochrome-c and p53 in mice brain during experimental fatal murine cerebral malaria.

    abstract::The levels of apoptosis associated proteins Bcl(2), Bax, cytochrome-c and p53 was investigated in mice cerebral cortex and cerebellum, using an experimental model of fatal murine cerebral malaria (FMCM). Owing to the activation of events central to mitochondrial dysfunctions, we monitored the structural integrity of m...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(02)00470-6

    authors: Kumar KA,Babu PP

    更新日期:2002-09-06 00:00:00

  • Endogenous CGRP protects retinal cells against stress induced apoptosis in rats.

    abstract::Acute stress can provoke apoptosis of the retina cells, and up-regulation of calcitonin gene related peptide (CGRP) in retina. However the role of CGRP in the pathology of the stress induced apoptosis of the retina cells is still elusive. The aim of this study was to investigate the endogenous of CGRP on retinal cell ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2011.06.049

    authors: Yang JH,Zhang YQ,Guo Z

    更新日期:2011-08-26 00:00:00

  • Effects of stimulus field size and coherence of visual motion on cortical responses in humans: an MEG study.

    abstract::Among various kinds of visual motion, wide field coherent visual motion should have characteristic physiological significance regarding the relationship between the external world and us. To detect veridical visual motion in the surrounding environment, specific mechanisms are necessary to differentiate it from the wi...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.11.050

    authors: Urakawa T,Inui K,Kakigi R

    更新日期:2011-01-25 00:00:00

  • Induction of memory-associated immediate early genes by nerve growth factor in rat primary cortical neurons and differentiated mouse Neuro2A cells.

    abstract::Activation of several immediate early genes (IEGs) is crucial for long-term memory formation in vivo. In vitro methods of inducing these genes have not been investigated extensively. Here we present data demonstrating that application of the neurotrophin, nerve growth factor (NGF), to both rat primary neuronal culture...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.04.089

    authors: Dickey CA,De Mesquita DD,Morgan D,Pennypacker KR

    更新日期:2004-08-05 00:00:00

  • Electrophysiological properties of lemniscal afferents in rat after kainic acid lesions in the ventrobasal thalamus.

    abstract::Kainic acid (KA) has been largely used as a neurotoxin, and its axon-sparing effect being repeatedly emphasized, on the basis of anatomical and biochemical data. The present study examines this 'axon-sparing' effect from an electrophysiological point of view and demonstrates that lemniscal fibers retain the capacity t...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(85)90068-0

    authors: Peschanski M,Briand A,Poingt JP,Guilbaud G

    更新日期:1985-08-05 00:00:00

  • Projections from the central nucleus of the amygdala to the gastric related area of the dorsal vagal complex: a Phaseolus vulgaris-leucoagglutinin study in rat.

    abstract::Electrophysiological and anatomic studies suggest that the amygdala regulates gastrointestinal motility and gastric acid secretion via projections to the dorsal vagal complex. The topography of these projections is poorly understood. Here, these projections were investigated by injecting anterograde tracer, Phaseolus ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01392-6

    authors: Liubashina O,Jolkkonen E,Pitkänen A

    更新日期:2000-09-15 00:00:00

  • Co-localization of substance P- and phenylethanolamine-N-methyltransferase-like immunoreactivity in neurons of ventrolateral medulla that project to the spinal cord: potential role in control of vasomotor tone.

    abstract::Both substance P (SP)- and epinephrine-containing neurons in the rostral ventrolateral medulla have been thought to play a role in regulating vasomotor tone. The combination of retrograde transport of a fluorescent dye (Fast Blue) and immunofluorescent staining for SP- and phenylethanolamine-N-methyltransferase (PNMT)...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(85)90444-6

    authors: Lorenz RG,Saper CB,Wong DL,Ciaranello RD,Loewy AD

    更新日期:1985-04-19 00:00:00

  • Nitric oxide donors attenuate clongenic potential in rat C6 glioma cells treated with alkylating chemotherapeutic agents.

    abstract::1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU) kills tumor cells via multiple actions including alkylation and carbamoylation. Previously, we have reported that formation of S-nitrosoglutathione (GSNO) in glioma cells overexpressing inducible nitric oxide synthase (iNOS) contributed to nitric oxide (NO)-dependent carbamo...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2007.03.011

    authors: Yang JJ,Yin JH,Yang DI

    更新日期:2007-05-11 00:00:00

  • Mechanisms and sites of pyrogenic action exerted by staphylococcal enterotoxin A in rabbits.

    abstract::The febrile responses induced by i.v. administrations of staphylococcal enterotoxin A (SEA) was mimicked by direct injection of SEA into the organum vasculosum laminae terminalis (OVLT) in unanesthetized rabbits. Compared with the febrile responses induced by i.v. injection of SEA, the OVLT route of injection required...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)00759-3

    authors: Huang WT,Lin MT,Won SJ

    更新日期:1997-10-24 00:00:00

  • The termination pattern of sciatic nerve afferents in the substantia gelatinosa of neonatal rats.

    abstract::A study was carried out to determine at what stage of development the adult pattern of primary afferent projections to the substantia gelatinosa (SG) is first established. Horseradish peroxidase conjugated wheat-germ agglutinin (WGA-HRP) was applied to cut ends of sciatic nerves at mid-thigh level in adult and neonata...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(83)90179-9

    authors: Fitzgerald M,Swett J

    更新日期:1983-12-30 00:00:00

  • Unilateral dorsal rhizotomy decreases monoamine levels in the rat spinal cord.

    abstract::In the rat, unilateral dorsal cervicothoracic rhizotomy (C5-T2) resulted in autotomy of the ipsilateral limb. The onset of self-mutilation was variable and attained the maximum degree 8-9 weeks after the dorsal root section. Fifteen and 60 days after the lesion the monoamines dopamine (DA), noradrenaline (NA) and sero...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(88)90466-1

    authors: Colado MI,Arnedo A,Peralta E,Del Río J

    更新日期:1988-05-03 00:00:00

  • The norepinephrine and dopamine content of the cat carotid body in vivo under normoxic and hypoxic conditions.

    abstract::The norepinephrine (NE) and dopamine (DA) content of the cat carotid body (CB) in vivo was investigated under normoxic and hypoxic conditions (5% O2 for 1 h) by radiolabelling method. To avoid a large scattering of the measured values due to inhomogeneity of the biological material, young sib animals were used. The me...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90664-6

    authors: Starlinger H,Acker H

    更新日期:1986-02-14 00:00:00

  • The interaction of tacrine with benzodiazepine and GABA binding sites of guinea pig brain.

    abstract::Tacrine (1,2,3,4-tetrahydro-9-acridinamine) inhibited binding of [3H]flunitrazepam to benzodiazepine receptors of guinea pig hippocampus with an inhibition constant of 46 microM at 2 degrees C and 37 degrees C. gamma-Aminobutyric acid (GABA) decreased the affinity of tacrine for the receptor, suggesting that tacrine m...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(91)90473-7

    authors: Dawson RM,Poretski M

    更新日期:1991-08-19 00:00:00

  • Effects of calcium antagonists on the evoked release of dynorphin A(1-8) and availability of intraterminal calcium in rat hippocampal mossy fiber synaptosomes.

    abstract::The pharmacological properties of presynaptic calcium (Ca) channels on rat hippocampal mossy fiber synaptosomes were characterized by determining the inhibitory potencies for various classes of Ca antagonists on depolarization-induced Ca mobilization and the release of dynorphin A(1-8)-like immunoreactivity (Dyn-LI). ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90184-5

    authors: Terrian DM,Damron DS,Dorman RV,Gannon RL

    更新日期:1989-12-04 00:00:00

  • A glycine antagonist reduces ischemia-induced CA1 cell loss in vivo.

    abstract::Excessive activation of the N-methyl-D-aspartate (NMDA) receptor-channel complex has been implicated as one of the mechanisms by which ischemia-induced neuronal damage is mediated. Elevated glycine levels during ischemia may contribute to damage mediated by the NMDA receptor as glycine binding potentiates NMDA respons...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90191-9

    authors: Wood ER,Bussey TJ,Phillips AG

    更新日期:1992-09-28 00:00:00

  • Motor cortex excitability in Alzheimer's disease: a transcranial magnetic stimulation follow-up study.

    abstract::Transient cognitive and behavioral stabilization of patients with Alzheimer's disease (AD) is the main goal of acetylcholinesterase inhibitor (AChEI) therapy. Response to treatment is variable and it is usually assessed clinically via neuropsychological scales. Functional neuroimaging could ideally permit the objectiv...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2011.01.064

    authors: Ferreri F,Pasqualetti P,Määttä S,Ponzo D,Guerra A,Bressi F,Chiovenda P,Del Duca M,Giambattistelli F,Ursini F,Tombini M,Vernieri F,Rossini PM

    更新日期:2011-04-01 00:00:00

  • Parvalbumin-immunoreactive neurons make inhibitory synapses on pyramidal cells in the human amygdala: a light and electron microscopic study.

    abstract::In the present study we investigate the inhibitory circuitries that regulate the neuronal activity in the lateral and basal nuclei, which are the main sensory input regions of the amygdala. Axon terminals immunoreactive for parvalbumin, a calcium-binding protein known to colocalize with GABA, were examined in these re...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:

    authors: Sorvari H,Miettinen R,Soininen H,Pitkänen A

    更新日期:1996-10-18 00:00:00

  • Detection of heparan sulfate in spinal spheroids of beta, beta'-iminodipropionitrile (IDPN)-treated rats.

    abstract::Beta,beta'-Iminodipropionitrile (IDPN) is known to produce a massive accumulation of neurofilaments in the proximal portion of axons of spinal anterior horn cells. The spinal cords of 20 Wistar rats treated with IDPN were examined immunohistochemically with a monoclonal antibody against heparan sulfate (HepSS-1). Virt...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)12225-7

    authors: Wada M,Kato T,Kurita K,Shikama Y,Toyoshima I,Sasaki H

    更新日期:1995-12-29 00:00:00

  • Meditation's impact on default mode network and hippocampus in mild cognitive impairment: a pilot study.

    abstract::Those with high baseline stress levels are more likely to develop mild cognitive impairment (MCI) and Alzheimer's Disease (AD). While meditation may reduce stress and alter the hippocampus and default mode network (DMN), little is known about its impact in these populations. Our objective was to conduct a "proof of co...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.neulet.2013.10.001

    authors: Wells RE,Yeh GY,Kerr CE,Wolkin J,Davis RB,Tan Y,Spaeth R,Wall RB,Walsh J,Kaptchuk TJ,Press D,Phillips RS,Kong J

    更新日期:2013-11-27 00:00:00

  • Factors in cerebrospinal fluid affecting motor activity in the rat.

    abstract::Cerebrospinal fluid (CSF) was obtained from donor rats either during the dark or during the light period of their diurnal cycle, and infused into the lateral ventricle of recipient rats. Infusing recipient rats during their dark period with CSF from light-exposed donors reduced the motor activity, whereas, conversely,...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(76)90028-8

    authors: Sachs J,Ungar J,Waser PG,Borbély AA

    更新日期:1976-04-01 00:00:00

  • Neuritogenic activity of peripheral nerve myelin proteins in Lewis rats.

    abstract::The neuritogenic activity of human peripheral nerve myelin proteins in Lewis rats was examined. Experimental allergic neuritis (EAN) was induced by human myelin fraction in all Lewis rats examined. Purified human P2 protein induced mild but definite EAN. None of purified P0 protein, total myelin lipids, gangliosides a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(80)90287-6

    authors: Suzuki M,Kitamura K,Uyemura K,Ogawa Y,Ishihara Y,Matsuyama H

    更新日期:1980-10-02 00:00:00

  • Time-dependent effects of oral morphine on autotomy following brachial nerve section in the rat.

    abstract::In this study, the effects of morphine in drinking water on autotomy in male F344 rats having undergone brachial nerve sections were assessed during a 3-week period. Morphine was self-administered orally in tap water by the rats. Rats administered morphine just after the nerve section or 1 week after the nerve section...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90886-c

    authors: Yamamoto T,Mizuguchi T

    更新日期:1992-07-20 00:00:00

  • Apelin-immunoreactivity in the rat hypothalamus and pituitary.

    abstract::With the use of an antiserum against human apelin-36, apelin-immunoreactivity (irAP) was detected in neurons and cell processes of the supraoptic nucleus (SO), paraventricular nucleus (PVH), accessory neurosecretory nuclei (Acc) and suprachiasmatic nucleus. Strongly labeled cells/processes were noted in the internal l...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(02)00411-1

    authors: Brailoiu GC,Dun SL,Yang J,Ohsawa M,Chang JK,Dun NJ

    更新日期:2002-07-26 00:00:00

  • Vascular endothelial growth factor expression under ischemic stress in human meningiomas.

    abstract::Vascular endothelial growth factor (VEGF) is an endothelial cell-specific antigen and angiogenic factor that plays a role in angiogenesis. We analyzed the expression of four VEGF mRNA isoforms in meningiomas. Among 35 meningiomas, 11 came from patients who underwent complete (n=4) or partial (n=7206=189 in all samples...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)00904-6

    authors: Park K,Kim JH,Nam DH,Lee JI,Kim JS,Hong SC,Shin HJ,Eoh W,Park K

    更新日期:2000-03-31 00:00:00

  • Neuroprotective effects of crocin against traumatic brain injury in mice: Involvement of notch signaling pathway.

    abstract::This study investigated the protective effects and mechanisms of crocin, an extract of saffron, on brain damage after traumatic brain injury (TBI) in mice. C57BL/6 mice were subjected to controlled cortical impact (CCI)-induced TBI. Pretreatment with crocin (20mg/kg) had protective effects against TBI, demonstrated by...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2015.02.016

    authors: Wang K,Zhang L,Rao W,Su N,Hui H,Wang L,Peng C,Tu Y,Zhang S,Fei Z

    更新日期:2015-03-30 00:00:00

  • Alpha(1)-adrenoceptor-mediated depolarization and beta-mediated hyperpolarization in cultured rat dorsal root ganglion neurones.

    abstract::The mechanism of sympathetic - sensory coupling after nerve injury is still not well understood. We have studied the changes in resting potential and excitability of sensory neurones induced by adrenergic stimulation, using whole-cell and perforated-patch recordings in cultured dorsal root ganglion neurones from norma...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(02)00665-1

    authors: Pluteanu F,Ristoiu V,Flonta ML,Reid G

    更新日期:2002-09-06 00:00:00