Abstract:
:Vascular endothelial growth factor (VEGF) is an endothelial cell-specific antigen and angiogenic factor that plays a role in angiogenesis. We analyzed the expression of four VEGF mRNA isoforms in meningiomas. Among 35 meningiomas, 11 came from patients who underwent complete (n=4) or partial (n=7206=189 in all samples. However, the VEGF121 and 165 isoforms were significantly upregulated in samples from patients who underwent partial preoperative embolization. The diffusible VEGF121 isoform may be important for vascularity and edema formation in meningiomas.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Park K,Kim JH,Nam DH,Lee JI,Kim JS,Hong SC,Shin HJ,Eoh W,Park Kdoi
10.1016/s0304-3940(00)00904-6keywords:
subject
Has Abstractpub_date
2000-03-31 00:00:00pages
45-8issue
1eissn
0304-3940issn
1872-7972pii
S0304-3940(00)00904-6journal_volume
283pub_type
杂志文章abstract::We have previously shown that treatment of cultured dorsal root ganglion neurons (DRGN) with a highly specific, reversible acetylcholinesterase (AChE) inhibitor, BW284c51, retards neuritic outgrowth in a dose dependent manner and is accompanied by the presence of abnormal, perikaryal neurofilament (NF) inclusions in a...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(95)11895-4
更新日期:1995-09-01 00:00:00
abstract::The opioid peptide dynorphin decreased somatic calcium-dependent action potential duration in a portion of mouse dorsal root ganglion (DRG) neurons without altering resting membrane potential or conductance. Dynorphin action was antagonized by naloxone. Responses of DRG neurons to dynorphin differed from responses to ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(84)90439-7
更新日期:1984-05-04 00:00:00
abstract::Recently, there has been a lot of interest in the neuroimaging community in exploring fMRI time-series measures of local neuronal activity and excitation/inhibition (E/I) balance in the brain. In this preliminary study we probed the sensitivity of widely used sample entropy (SE) measure at multiple scales to controlle...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2020.134984
更新日期:2020-05-29 00:00:00
abstract::The uptake of 2-deoxy-[14C]glucose (2-DG) by motor neurons in adult rat hypoglossal nuclei was studied 3 days after subepineural injection of 'crude' soluble protein extracts from intact and injured peripheral nerves into normal hypoglossal nerves. Injured nerve extracts were obtained from 'proximal' and 'distal' segm...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(88)90400-4
更新日期:1988-01-22 00:00:00
abstract::Mesial temporal lobe epilepsy (MTLE) is a common type of intractable epilepsy characterized by astroglial gliosis. The S100B was viewed as an astrocyte marker and experimental studies indicated that S100B might be involved in the pathophysiology of temporal lobe epilepsy. In this study, we measured plasma S100B levels...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2010.08.036
更新日期:2010-10-29 00:00:00
abstract::The mechanism of action of the 'geste antagonistique', or sensory trick, used by patients with dystonic blepharospasm (BSP) to transiently diminish their symptoms is presently unknown. In this paper we examined the effects induced by a sensory trick consisting of finger contact with the face on the electrically induce...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(98)00519-9
更新日期:1998-07-24 00:00:00
abstract::The presence of serotonin (5-HT)-like immunoreactivity has been detected in ganglionar cell bodies of the nodose ganglia of the cat, using the peroxidase-antiperoxidase immunohistochemical method, applied to sections of ganglia previously embedded in paraffin. The antibodies were raised in rabbits following injection ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(82)90246-4
更新日期:1982-11-30 00:00:00
abstract::A study was carried out to determine at what stage of development the adult pattern of primary afferent projections to the substantia gelatinosa (SG) is first established. Horseradish peroxidase conjugated wheat-germ agglutinin (WGA-HRP) was applied to cut ends of sciatic nerves at mid-thigh level in adult and neonata...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(83)90179-9
更新日期:1983-12-30 00:00:00
abstract::It is known that 5HTR2A (rs6311) receptors have high concentration in the cortical layer-5 pyramidal neurons and that these receptors play an important role in the modulation of neurocognitive functions. For example, layer-5 pyramidal neurons mediate cellular level integrative interaction of primary sensory afferent s...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2014.10.015
更新日期:2015-01-01 00:00:00
abstract::The potential neurotoxicity of the solvent toluene to the nigrostriatal dopaminergic system was assessed in a rat model of Parkinson's disease. Rats, 1 day after a unilateral injection of 6-hydroxydopamine (6-OH DA) into the substantia nigra, inhaled air or different concentrations of toluene (80, 300 or 1000 ppm), 6 ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(96)13049-4
更新日期:1996-10-11 00:00:00
abstract::Alzheimer's disease (AD) is still difficult to be precisely diagnosed in its early stage to date. Establishing of reliable and manageable disease-specific biological markers is required to improve diagnostic accuracy. Based on the hypothesis of cell cycle regulatory failure at the early stage of AD, we tested whether ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2012.03.093
更新日期:2012-05-16 00:00:00
abstract::A cDNA clone encoding a novel protein (Cer-1) was isolated from a mouse cerebellar cDNA library. The deduced amino acid sequence of Cer-1 is not homologous to other sequences in the protein sequence data base. RNA blot analysis suggests that expression of Cer-1 RNA occurs selectively in the adult cerebellum and in pur...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(96)12628-8
更新日期:1996-05-10 00:00:00
abstract::Antidromic action potentials were recorded from rat paraventricular nucleus (PVN) and supraoptic nucleus neurons following electrical stimulation of the pituitary stalk. Increases in stimulation frequency to 10 or 20 Hz caused progressive increases in antidromic latency and, often, failure of the antidromic potential ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(83)90437-8
更新日期:1983-06-30 00:00:00
abstract::Benzodiazepine (BZ) recognition sites of the 'peripheral' type were localized autoradiographically in human postmortem brain and kidney using [3H]Ro 5-4864. These sites presented a relatively homogeneous distribution. Areas such as the ependyma, choroid plexus and olfactory bulb, which in the rat are very rich in thes...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(86)90181-3
更新日期:1986-05-15 00:00:00
abstract::Nitric oxide synthase (NOS) immunoreactivity occurred in about 60% of ventromedial, ventrolateral, and sphincteric motoneurones in cat sacral spinal cord. Proportions of sacral motoneurones histochemically stained for NADPH-diaphorase, were similar, and equivalent in size to those immunoreactive for NOS, suggesting co...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(95)11831-g
更新日期:1995-08-18 00:00:00
abstract::beta-N-Oxalylamino-L-alanine (BOAA) and beta-N-methylamino-L-alanine (BMAA) were tested for their ability to produce acute excitotoxicity in in embryonic chick retina. gamma-Aminobutyric acid (GABA) release and histology were monitored in retina treated with various concentrations of BOAA, BMAA, kainate (KA), N-methyl...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(89)90093-1
更新日期:1989-07-31 00:00:00
abstract::Application of strychnine sulfate (10-50 mu M) to the anterior hindlimb enlargement of the turtle spinal cord increased the amplitude of the ipsilateral fictive flexion reflex and revealed a contralateral (crossed) fictive flexion reflex response to cutaneous stimulation of the foot. Strychnine abolished the crossed i...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(96)12387-9
更新日期:1996-02-23 00:00:00
abstract::We have used in situ hybridization with biotinylated oligonucleotide (antisense) probes and streptavidin-biotinylated alkaline phosphatase method to detect the amount of amyloid beta-protein mRNA in the paraffin-embedded and formalin-fixed brain samples of patients affected by Alzheimer's disease and those of non-affe...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(91)90234-k
更新日期:1991-09-02 00:00:00
abstract::Exposure to alcohol in utero has been associated with hypothyroidism and a variety of developmental defects characteristic of thyroid dysfunction. The present work examined whether these abnormalities could be reversed in infant rats treated with thyroid hormones. Subjects were offspring of dams which were on the foll...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(90)90535-h
更新日期:1990-02-05 00:00:00
abstract::Free radical generation and release from the cerebral hemispheres of rats subjected to four-vessel occlusion elicited cerebral ischemia/reperfusion was monitored using a cortical cup technique with the spin-trapping agent alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone (POBN). Electron spin resonance (ESR) was used to d...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(94)90388-3
更新日期:1994-03-14 00:00:00
abstract::The distribution pattern of sialylated glycoproteins in the hippocampal formation of 9-week-old and 29-month-old rats was examined using Maackia amurensis lectin, specific for Sia alpha2-3Gal, and Sambucus sieboldiana agglutinin specific for Sia alpha2-6Gal(GalNAc), and a monoclonal antibody for a linear homopolymer o...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(99)00032-4
更新日期:1999-02-26 00:00:00
abstract::Since the mRNA level of Fyn, a neurodevelopmental molecule, expression had been reported to be increased in postmortem schizophrenic prefrontal cortex and showed a strong correlation with age of disease onset, we investigated whether the three polymorphisms of the Fyn gene on genomic DNA (-93A/G, IVS10+37T/C and Ex12+...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(03)00310-0
更新日期:2003-05-29 00:00:00
abstract::Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors occur throughout the nervous system, including the retina. PACAP exerts diverse actions in the eye: it influences ocular blood flow, contraction of the ciliary muscle, and has retinoprotective effects. This effect has been proven in different...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2010.10.065
更新日期:2011-01-10 00:00:00
abstract::Central dopaminergic systems have been implicated in the regulation of blood pressure. We examined the effect on blood pressure of electrical or chemical stimulation of the rat brain ventral tegmental area (VTA) which is the region of origin of the A10 dopaminergic system. Electrical stimulation in urethane-anaestheti...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(94)90068-x
更新日期:1994-08-01 00:00:00
abstract::Sex steroids have potent effects on mood, mental state and cognition. Our previous findings and those of others suggest that these effects may be due at least in part to estradiol actions on central serotonergic mechanisms. Specifically, estradiol-17beta in its acute positive feedback mode for gonadotropin release in ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2007.02.039
更新日期:2007-04-24 00:00:00
abstract::Morphine hydrochloride (10 mg/kg,i.p.) induced marked catalepsy in rats, which was associated with significantly enhanced striatal acetylcholine levels and reduced cholinesterase activity. Rapid tolerance to morphine-induced catalepsy was noted after twice daily administrations, the tolerance being discernible after t...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(79)95355-2
更新日期:1979-09-01 00:00:00
abstract::Technologies for wireless telecommunication systems using millimeter waves (MMW) will be widely deployed in the near future. Forthcoming applications in this band, especially around 60GHz, are mainly developed for high data-rate local and body-centric telecommunications. At those frequencies, electromagnetic radiation...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2016.02.038
更新日期:2016-04-08 00:00:00
abstract::Probiotics participate actively in the neuropsychiatric disorders. However, their roles on ischemic stroke remain unclear. This study aims to determine whether Clostridium butyricum (C. butyricum) could attenuate cerebral ischemia/reperfusion (I/R) injury and its possible mechanisms. Male ICR mice were intragastricall...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2015.12.047
更新日期:2016-02-02 00:00:00
abstract::Four new tactile areas in the cerebellar cortex (crus I, crus II, paramedian lobule and uvula) have recently been described in the rat. Ipsilateral orofacial regions are chiefly represented in these areas. Our study of trigeminocerebellar afferents to these areas using the HRP retrograde tracing technique shows that t...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(78)90015-0
更新日期:1978-11-01 00:00:00
abstract::In human caudate and cortex membranes, [3H]serotonin ([3H]5-HT) labels 5-HT1A and 5-HT1C recognition sites which show nanomolar affinity for 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)-tetralin) and mesulergine respectively, whereas no 5-HT1B binding could be identified. However, the majority of the sites labelled by [3...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(88)90592-7
更新日期:1988-03-10 00:00:00