A novel gene selectively expressed in the cerebellum.

abstract：:The antinociceptive action of cannabinoids in acute and inflammatory pain states have been well-documented. There is also accumulating evidence suggesting that cannabinoids are effective analgesics in chronic pain conditions. WIN 55,212-2, a mixed CB1 and CB2 cannabinoid receptor agonist, has been shown to be effectiv...

journal_title：Neuroscience letters

authors： Ulugol A,Karadag HC,Ipci Y,Tamer M,Dokmeci I

更新日期：2004-11-23 00:00:00

abstract：:We observed the changes of body temperature and the cytokine expressions in the hypothalamus of rats to investigate the effect and mechanism of antipyretic action of acupuncture. Lipopolysaccharide (LPS, i.p., 2.5 mg/kg) was injected into rats and manual acupuncture was performed on Shaofu (HT8), Zutonggu (BL66) or Xi...

journal_title：Neuroscience letters

authors： Son YS,Park HJ,Kwon OB,Jung SC,Shin HC,Lim S

更新日期：2002-02-08 00:00:00

abstract：:Dendritic branching of neurons may be quantitatively studied using applications of graph theory. Dendritic ramifications may be considered as 'forests' of planted, stemmed, binary 'trees' with simple mathematical properties. Two fundamental numbers, that of dendritic tips and that of dendritic stems, usually suffice t...

journal_title：Neuroscience letters

authors： Percheron G

更新日期：1979-10-01 00:00:00

abstract：:Previous studies have demonstrated that both visual and proprioceptive feedback influence motor control. The relative contributions of these sensory modalities to the on-line computation of body position--that is, the body schema--remain unclear. We report a study designed to explore the roles of vision and propriocep...

journal_title：Neuroscience letters

authors： Shenton JT,Schwoebel J,Coslett HB

更新日期：2004-11-03 00:00:00

abstract：:Estrogen effects on pineal secretion of melatonin are controversial. Some feel that estrogen inhibits melatonin output in vitro but not in vivo. Melatonin levels vary with the age in chickens where circulating estrogen levels also vary. Laying hens have minimal melatonin levels and maximal serum iron concentrations. T...

journal_title：Neuroscience letters

authors： Pablos MI,Agapito MT,Recio JM,Pérez-Gallardo L,Córdova MD,Mori JO

更新日期：1993-09-03 00:00:00

abstract：:The death of neurons after brain ischaemia may be associated with activation of cyclin-dependent kinases (CDKs) and upregulation of cyclins, reflecting aberrant entry of neurons into the cell cycle. Little has been published on the expression of cell cycle proteins after brain ischaemia in man. Well-characterized anti...

journal_title：Neuroscience letters

authors： Love S

更新日期：2003-12-15 00:00:00

abstract：:Wild-type neuronal calcium-binding protein VILIP (visinin-like protein), and a myristoylation mutant of VILIP which lacks the consensus sequence for N-terminal myristoylation, have been stably transfected in PC12 cells. Immunocytochemical studies of VILIP-transfected PC12 cells have revealed the wild-type VILIP is str...

journal_title：Neuroscience letters

authors： Spilker C,Gundelfinger ED,Braunewell KH

更新日期：1997-04-04 00:00:00

abstract：:Recent findings document numerous interactions between neuronal and glial systems that likely play a role in the pathophysiology of depression. These findings suggest that glia-derived neurotrophic protein S100B may play a significant role in developing depression. To test the relationship between S100B and depressive...

journal_title：Neuroscience letters

authors： Uher T,Bob P

更新日期：2012-11-07 00:00:00

abstract：:The effect of partial isomerization of dietary alpha-linolenic acid on the monoaminergic neurotransmitters in piglets was studied. After feeding the animals for 14 days with diets containing or not trans alpha-linolenic acid, neurotransmitters related to the monoaminergic function were quantified in the frontal cortex...

journal_title：Neuroscience letters

authors： Acar N,Chardigny JM,Berdeaux O,Almanza S,Sébédio JL

更新日期：2002-10-18 00:00:00

abstract：:Abnormalities of the white matter (WM) tracts integrity in brain areas involved in emotional regulation have been postulated in major depressive disorder (MDD). However, there is no diffusion tensor imaging (DTI) study in patients with treatment-responsive MDD at present. DTI scans were performed on 22 patients with t...

journal_title：Neuroscience letters

authors： Guo WB,Liu F,Xue ZM,Gao K,Wu RR,Ma CQ,Liu ZN,Xiao CQ,Chen HF,Zhao JP

更新日期：2012-08-01 00:00:00

abstract：:Dysbindin gene (DTNBP1) has been associated with schizophrenia, but literature findings are inconsistent, and further analyses are required. This study is aimed to investigate if a set of DTNBP1 variations might influence clinic psychotic phenotype or treatment response in a sample of 240 Korean schizophrenic in-patie...

journal_title：Neuroscience letters

authors： Pae CU,Drago A,Kim JJ,Patkar AA,Jun TY,Lee C,Mandelli L,De Ronchi D,Paik IH,Serretti A

更新日期：2008-08-01 00:00:00

abstract：:Using in situ hybridisation with an oligonucleotide probe, the regional distribution of GABA transporter-1 messenger RNA was determined in the adult rat CNS. Overall, the distribution of GABA transporter-1 mRNA was similar to that of glutamate decarboxylase-67 mRNA, consistent with an expression in GABA neurones. Howe...

journal_title：Neuroscience letters

authors： Rattray M,Priestley JV

更新日期：1993-06-25 00:00:00

abstract：:The 22Na+ efflux stimulated by selected agonists of the 4 excitatory amino acid receptors, previously detected in the striatum, has been studied on 22Na+-preloaded slices prepared from 10 major areas of the rat brain. All brain areas were found to be sensitive, albeit to varying extents, to excitatory amino acids. The...

journal_title：Neuroscience letters

authors： Luini A,Goldberg O,Teichberg VI

更新日期：1983-11-11 00:00:00

abstract：:Hypoxic encephalopathy is a common cause of neonatal seizures and long-term neurological cognitive deficits. In rats at postnatal days 10-12 (P10-P12), global hypoxia induced spontaneous seizures and chronic brain injury, mimicking clinical aspects of neonatal hypoxia. Synaptic Ras-GTPase activating protein (SynGAP) h...

journal_title：Neuroscience letters

authors： Yang SN,Huang CB,Yang CH,Lai MC,Chen WF,Wang CL,Wu CL,Huang LT

更新日期：2004-11-16 00:00:00

abstract：:Interstitial cells of Cajal (ICCs) play a key role in regulating gastrointestinal tract motility. The pathophysiological basis of colonic aperistalsis in Hirschsprung's disease (HD) is still not fully understood. Many studies reported that decreased numbers or disrupted networks of ICCs were associated with HD. Little...

journal_title：Neuroscience letters

authors： Wang H,Zhang Y,Liu W,Wu R,Chen X,Gu L,Wei B,Gao Y

更新日期：2009-02-27 00:00:00

abstract：:Motor nerve supplies to 15 poles of rat lumbrical spindle were reconstructed from serial, 1-micron transverse sections of muscle embedded in resin. Neural and muscular elements associated with the modulation of static sensitivity of afferents were deficient in these spindles relative to cat tenuissimus and rat soleus ...

journal_title：Neuroscience letters

authors： Walro JM,Kucera J

更新日期：1985-09-06 00:00:00

abstract：:Rapid balance reactions such as compensatory reach to grasp represent important response strategies following unexpected loss of balance. While it has been assumed that early corrective actions arise from subcortical networks, recent research has prompted speculation about the potential role of cortical involvement. W...

journal_title：Neuroscience letters

authors： Bolton DAE,Patel R,Staines WR,McIlroy WE

更新日期：2011-10-24 00:00:00

abstract：:The possibility that single electrical shock stimulation of somatic afferent nerves could evoke a reflex response in vagal efferent nerves innervating the stomach was examined using anesthetized, artificially-ventilated rats. A single shock to a hindlimb afferent nerve (tibial nerve) produced two distinct reflex compo...

journal_title：Neuroscience letters

authors： Kimura A,Sato A,Sato Y,Suzuki A

更新日期：1996-05-24 00:00:00

abstract：:Aquaporin-1 (AQP1) is a water channel expressed in the choroid plexus and participates in forming cerebrospinal fluid. Interestingly, reactive astrocytes also express AQP1 in the central nervous system under some pathological conditions. On the other hand, 3-nitropropionic acid (3NP) is a mitochondrial toxin that caus...

journal_title：Neuroscience letters

authors： Hoshi A,Tsunoda A,Yamamoto T,Tada M,Kakita A,Ugawa Y

更新日期：2016-07-28 00:00:00

abstract：:The anti-neuroinflammatory effect of Astragaloside IV (ASI) has been reported, but its underlying mechanisms are unclear. This study is further to explore the underlying mechanism of ASI on anti-neuroinflammatory effect in LPS induced microglia cells. The result showed ASI significantly reduced the production of infla...

journal_title：Neuroscience letters

authors： Li C,Yang F,Liu F,Li D,Yang T

更新日期：2018-02-14 00:00:00

abstract：:Although synaptically released, vesicular Zn(2+) has been proposed to play a neuromodulatory or neuronal signaling role at the mossy fiber-CA3 synapse, Zn(2+) release remains controversial, especially when detected using fluorescent imaging. In the present study, we investigated synaptically released Zn(2+) at the mos...

journal_title：Neuroscience letters

authors： Bastian C,Li YV

更新日期：2007-05-29 00:00:00

abstract：:The morphology of somatosensory evoked fields (SEF) following electrical separate stimulation of left and right median nerve in 22 healthy volunteers was explored. The analysis of morphological properties of individual SEFs has been performed, in order to quantify an inter-hemispheric correlation coefficient. Despite ...

journal_title：Neuroscience letters

authors： Tecchio F,Pasqualetti P,Pizzella V,Romani G,Rossini PM

更新日期：2000-06-30 00:00:00

abstract：:Behavioral responses and neural responses in the somatosensory cortex were recorded in nine rabbits during the unpaired and paired treatments of classical eyeblink conditioning with a tone conditioned stimulus (CS) and an airpuff unconditioned stimulus. During the unpaired treatment, neither the behavioral nor neural ...

journal_title：Neuroscience letters

authors： Wikgren J,Ruusuvirta T,Korhonen T

更新日期：2003-05-01 00:00:00

abstract：:The binding site for 1,4-benzodiazepines in the brain is part of the hetero-oligomeric gamma-aminobutyric acid (GABA)A receptor complex which regulates a chloride ion channel. The presence of the gamma 2 subunit in the complex is necessary for the binding of benzodiazepines to their binding site. This study demonstrat...

journal_title：Neuroscience letters

authors： Karle J,Witt MR,Nielsen M

更新日期：1995-12-29 00:00:00

abstract：:The administration of DN-1417, a synthetic derivative of TRH with more potent central action, significantly reduced specific [3H]GABA binding in the cerebellum, whereas [3H]GABA binding in the cerebral cortex was not changed. Scatchard analysis showed that the decreased [3H]GABA binding in the cerebellum was due to de...

journal_title：Neuroscience letters

authors： Tatsuoka Y,Kato Y,Imura H

更新日期：1983-12-02 00:00:00

abstract：:Administration of the cannabinoid CB1 receptor antagonist SR141716 (3-10 mg/kg i.p.) abolished neuropeptide Y-induced overeating and significantly reduced ethanol and sucrose intake in CB1 wild-type (+/+) mice. In CB1 receptor knockout (-/-) mice, neuropeptide Y totally lost its capacity to increase food consumption. ...

journal_title：Neuroscience letters

authors： Poncelet M,Maruani J,Calassi R,Soubrié P

更新日期：2003-06-12 00:00:00

abstract：:The aim of the present study was to investigate the intrathecal (i.t.) action of a selective A1-adenosine receptor agonist, R-phenylisopropyl adenosine (R-PIA), on tactile withdrawal thresholds in a rat model of mononeuropathy produced by sciatic chronic constriction injury (CCI). An additional aim was to examine whet...

journal_title：Neuroscience letters

authors： Cui JG,Sollevi A,Linderoth B,Meyerson BA

更新日期：1997-02-28 00:00:00

abstract：:The present study was designed to determine potential associations between the brain damage induced by hypoxic-ischemic (HI) insult and spatial learning impairment in an eight-arm radial maze task. We first determined the pathological outcomes after 2, 5, 9, and 17 weeks of recovery following the HI insult. The result...

journal_title：Neuroscience letters

authors： Mishima K,Ikeda T,Aoo N,Takai N,Takahashi S,Egashira N,Ikenoue T,Iwasaki K,Fujiwara M

更新日期：2005-03-16 00:00:00

abstract：:The cerebral vessels have sympathetic, parasympathetic, and sensory innervations. A sensory innervation of the cerebral vessels originating in the trigeminal ganglion has been described in a number of species by several investigations. It has been shown that the electrical stimulation of the trigeminal ganglion causes...

journal_title：Neuroscience letters

authors： Gürelik M,Karadağ O,Polat S,Ozüm U,Aslan A,Gürelik B,Göksel HM

更新日期：2004-07-29 00:00:00

abstract：:Prolonged exposure of hippocampal slices to L-glutamate was found to produce a biphasic effect on excitatory synaptic transmission from Schaffer collateral-commissural fibers to CA1 pyramidal neurons: an early blockade of postsynaptic responses was followed by a progressive recovery. Antagonists of N-methyl-D-aspartat...

journal_title：Neuroscience letters

authors： Krishtal OA,Smirnov SV,Osipchuk YuV

更新日期：1988-02-15 00:00:00