Effect of iron and estrogen on melatonin secretion by the chicken pineal gland.

Abstract:

:Estrogen effects on pineal secretion of melatonin are controversial. Some feel that estrogen inhibits melatonin output in vitro but not in vivo. Melatonin levels vary with the age in chickens where circulating estrogen levels also vary. Laying hens have minimal melatonin levels and maximal serum iron concentrations. Thus, we reasoned that iron released by estrogen may inhibit melatonin secretion from the chick pineal gland. The present study shows that perifusion of estrogen-treated chick pineal glands with several concentrations of iron greatly inhibited melatonin secretion.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Pablos MI,Agapito MT,Recio JM,Pérez-Gallardo L,Córdova MD,Mori JO

doi

10.1016/0304-3940(93)90836-a

subject

Has Abstract

pub_date

1993-09-03 00:00:00

pages

211-4

issue

1-2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(93)90836-A

journal_volume

159

pub_type

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