Abstract:
:Theta rhythms in the hippocampus are believed to be the "metric" relating to various behavior patterns for free roaming rats. In this study, the theta rhythms were studied while rats either walked or were passively translated by a toy car on a linear track (referred to as WALK and TRANS respectively). For the similar running speeds in WALK and TRANS conditions, theta frequency and amplitude were both reduced during TRANS. Theta modulation of pyramidal cells during TRANS was reduced compared to that during WALK. Theta frequency was positively correlated with translation speed during TRANS. Theta rhythm remained apparent during TRANS and WALK after large dose of atropine sulfate (blocking the cholinergic pathway) was injected compared to still states. The present study demonstrated the patterns of theta rhythm induced by passive translation in rats and suggested that the Type I theta rhythm could occur during non-voluntary locomotion. We further argued that the perception of actual self-motion may be the underlying mechanism that initiates and modulates type I theta.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Xie K,Yan Y,Fang X,Gao S,Hong Bdoi
10.1016/j.neulet.2012.03.005subject
Has Abstractpub_date
2012-04-25 00:00:00pages
18-22issue
1eissn
0304-3940issn
1872-7972pii
S0304-3940(12)00354-0journal_volume
515pub_type
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