Characteristics and classification of hippocampal θ rhythm induced by passive translational displacement.

Abstract:

:Theta rhythms in the hippocampus are believed to be the "metric" relating to various behavior patterns for free roaming rats. In this study, the theta rhythms were studied while rats either walked or were passively translated by a toy car on a linear track (referred to as WALK and TRANS respectively). For the similar running speeds in WALK and TRANS conditions, theta frequency and amplitude were both reduced during TRANS. Theta modulation of pyramidal cells during TRANS was reduced compared to that during WALK. Theta frequency was positively correlated with translation speed during TRANS. Theta rhythm remained apparent during TRANS and WALK after large dose of atropine sulfate (blocking the cholinergic pathway) was injected compared to still states. The present study demonstrated the patterns of theta rhythm induced by passive translation in rats and suggested that the Type I theta rhythm could occur during non-voluntary locomotion. We further argued that the perception of actual self-motion may be the underlying mechanism that initiates and modulates type I theta.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Xie K,Yan Y,Fang X,Gao S,Hong B

doi

10.1016/j.neulet.2012.03.005

subject

Has Abstract

pub_date

2012-04-25 00:00:00

pages

18-22

issue

1

eissn

0304-3940

issn

1872-7972

pii

S0304-3940(12)00354-0

journal_volume

515

pub_type

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