Abstract:
:Using in situ hybridisation with an oligonucleotide probe, the regional distribution of GABA transporter-1 messenger RNA was determined in the adult rat CNS. Overall, the distribution of GABA transporter-1 mRNA was similar to that of glutamate decarboxylase-67 mRNA, consistent with an expression in GABA neurones. However, in cerebellar cortex, Purkinje cells which express high levels of glutamate decarboxylase-67 mRNA did not express GABA transporter-1 mRNA, whereas Bergmann glia expressed GABA transporter-1 mRNA at high levels. In some other brain regions, including the inferior colliculus and reticular thalamus, there was no GABA transporter-1, although there were neurones which expressed glutamate decarboxylase-67 messenger RNA at high levels.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Rattray M,Priestley JVdoi
10.1016/0304-3940(93)90463-usubject
Has Abstractpub_date
1993-06-25 00:00:00pages
163-6issue
1-2eissn
0304-3940issn
1872-7972pii
0304-3940(93)90463-Ujournal_volume
156pub_type
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