Plasminogen enhances the secretion of plasminogen activator inhibitor-1 from cultured rat astrocytes.

abstract：:The expression of metabotropic glutamate receptor 8 (mGluR8) was studied in the rat hippocampus after pilocarpine-induced status epilepticus (APISE) by light immunohistochemistry and immunoelectron microscopy. At 1 day APISE, mGluR8 immunoreactivity was up-regulated in the entire molecular layer of the dentate gyrus. ...

journal_title：Neuroscience letters

authors： Tang FR,Lee WL,Yang J,Sim MK,Ling EA

更新日期：2001-03-16 00:00:00

abstract：:To determine whether diabetes mellitus alters the lipid order and composition of cerebral microvessels, streptozotocin-induced diabetic rats were studied after 5 weeks of chronic hyperglycemia. Diabetes did not affect membrane order or the thermotropic transition temperature of cerebral microvessels as determined from...

journal_title：Neuroscience letters

authors： Mooradian AD,Smith TL

更新日期：1992-10-12 00:00:00

abstract：:Functional MRI studies have revealed that the brain activity in the anterior temporal cortex during memory retrieval increases over months after memory encoding. Behavioral evidence has demonstrated that long-term memory can sometimes be consolidated more rapidly in one or two days. In the present functional MRI study...

journal_title：Neuroscience letters

authors： Jimura K,Hirose S,Wada H,Yoshizawa Y,Imai Y,Akahane M,Machida T,Shirouzu I,Koike Y,Konishi S

更新日期：2016-08-03 00:00:00

abstract：:A push-pull perfusion technique was used to sample third ventricular cerebrospinal fluid (CSF) in the conscious rat. Ventricular perfusate contained significant quantities of vasopressin and oxytocin, 13.1 and 4.5 pg/ml, respectively. Vasopressin and oxytocin levels were stable over a 3 h perfusion period. High sodium...

journal_title：Neuroscience letters

authors： Barnard RR Jr,Morris M

更新日期：1982-04-26 00:00:00

abstract：:This study explored whether patients with Parkinson's disease alter the regulation of upright standing according to constraints imposed by the environmental context. The provision of context-dependent adaptations was inferred from the presence of adjustments to standing postural control that would serve to reduce fall...

journal_title：Neuroscience letters

authors： Brown LA,Doan JB,Whishaw IQ,Suchowersky O

更新日期：2007-05-18 00:00:00

abstract：:NGP1-01, a member of the pentacycloundecylamine cage compound family, was recently shown to exhibit both NMDA receptor channel blocking and L-type calcium channel antagonism activity. In the present study, focal ischemia was induced in mice by permanent middle cerebral artery occlusion (MCAO) to test for potential neu...

journal_title：Neuroscience letters

authors： Mdzinarishvili A,Geldenhuys WJ,Abbruscato TJ,Bickel U,Klein J,Van der Schyf CJ

更新日期：2005-07-22 00:00:00

abstract：:Restoration of autophagy represents a potential therapeutic target for neurodegenerative disorders, but factors that regulate autophagic flux are largely unknown. When deprived of trophic factors, cultured Purkinje neurons die by an autophagy associated cell death mechanism. The accumulation of autophagic vesicles and...

journal_title：Neuroscience letters

authors： Bains M,Zaegel V,Mize-Berge J,Heidenreich KA

更新日期：2011-01-20 00:00:00

abstract：:Little is known about the effect of wnt-3a on motor nerve function and its specific molecular mechanisms after spinal cord injury (SCI). This study demonstrates that the downregulated expression levels of caspases-3, caspases-9 and chondroitin sulfate proteoglycan (CSPG) proteins and number of proportion of transferas...

journal_title：Neuroscience letters

authors： Gao K,Niu J,Dang X

更新日期：2020-10-15 00:00:00

abstract：:Stress increases associative learning and the density of dendritic spines in the hippocampus of male rats. In contrast, exposure to the same stressor impairs associative learning and reduces spine density in females. These effects in females are most evident when they are in the proestrus phase of the estrous cycle. A...

journal_title：Neuroscience letters

authors： Dalla C,Whetstone AS,Hodes GE,Shors TJ

更新日期：2009-01-02 00:00:00

abstract：:The distribution and cellular localisation of somatostatin receptor subtype 4 (SSTR4) was investigated in the adult rat brain using the technique of in situ hybridisation with subtype specific oligonucleotide probes. Somatostatin receptor subtype 4 was found mainly in the hippocampus CA1 > CA2 > CA3 pyramidal cells an...

journal_title：Neuroscience letters

authors： Harrington KA,Schindler M,Humphrey PP,Emson PC

更新日期：1995-03-16 00:00:00

abstract：:Human low back pain sometimes originates from lumbar facet joints. In human lumbar facet joint inflammation or degeneration, the referred pain is not only expanded into the low back area but also into the leg or foot. The rat L5-L6 facet joint is innervated by the L1-L5 dorsal root ganglia. The presence of brain-deriv...

journal_title：Neuroscience letters

authors： Ohtori S,Takahashi K,Moriya H

更新日期：2002-04-26 00:00:00

abstract：:The expression of neuronal type of nitric oxide synthase (nNOS) has been studied by immunocytochemistry in the brain of rats receiving a single daily (for up to 14 consecutive days) intracerebroventricular (i.c.v.) injection of the HIV-1 recombinant protein gp 120 (100 ng/day). This treatment failed to affect nNOS exp...

journal_title：Neuroscience letters

authors： Bagetta G,Corasaniti MT,Costa N,Berliocchi L,Finazzi-Agrò A,Nisticò G

更新日期：1997-03-14 00:00:00

abstract：:Herpes simplex virus encephalitis (HSVE) causes elevated morbidity and mortality despite antiviral treatment. Virus-independent mechanisms may perpetuate brain damage. Matrix metalloproteinases (MMPs) target extracellular matrix components. This study describes the protein and mRNA expression of MMP2 and MMP9 in exper...

journal_title：Neuroscience letters

authors： Martínez-Torres FJ,Wagner S,Haas J,Kehm R,Sellner J,Hacke W,Meyding-Lamadé U

更新日期：2004-09-30 00:00:00

abstract：:To investigate the relationship between apolipoprotein E (APOE) polymorphisms and the severity of traumatic brain injury (TBI) in acute stage in the cohort of mainland Chinese patients. We prospectively identified admissions to the two neurosurgical departments for head injury. A total of 110 subjects with TBI (80 mal...

journal_title：Neuroscience letters

authors： Jiang Y,Sun X,Xia Y,Tang W,Cao Y,Gu Y

更新日期：2006-11-13 00:00:00

abstract：:Viral infections are frequently found in opioid addicts, subjecting them to immune challenge. However, the effects of immune challenge on opioid withdrawal are not fully understood. In the present study, mice were intraperitoneally injected with 2mg/kg polyinosinic-polycytidylic acid (Poly I:C, a viral mimetic) for 3 ...

journal_title：Neuroscience letters

authors： Chen L,Zhai H,Lu L,Chen S,Ning Y,Wang W

更新日期：2011-01-10 00:00:00

abstract：:Alternate serial 1 micron Durcupan resin sections of tiger salamander retina were stained with antisera against GABA and glycine using postembed immunocytochemical techniques. Although the vast majority of neurons were labeled by either GABA or glycine antiserum, a small percentage of presumed amacrine cells in the in...

journal_title：Neuroscience letters

authors： Yazulla S,Yang CY

更新日期：1988-12-19 00:00:00

abstract：:The effects of Ga-Al-As diode laser (830 nm, 16.2 mW) irradiation on the distal portion of the processes of cultured murine dorsal root ganglion (DRG) neurons associated with C-fibers were studied by patch-clamp whole-cell recording of membrane potentials at the cell body. The chemical as well as laser light stimulati...

journal_title：Neuroscience letters

authors： Jimbo K,Noda K,Suzuki K,Yoda K

更新日期：1998-01-09 00:00:00

abstract：:We have previously shown that 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (H7), an inhibitor of protein kinase C, inhibits proliferation of neuroblastoma cells in culture. We have now tested whether the effect of H7 is mediated by MAP kinase and Raf. It is shown that, in Neuro 2a cells, activation of protein kinase...

journal_title：Neuroscience letters

authors： Cabedo H,Felipo V,Miñana MD,Grisolía S

更新日期：1996-08-16 00:00:00

abstract：:Effect of (+)-epi-clausenamide and (-)-epi-clausenamide on synaptic transmission in CA1 region of hippocampal slice was compared in this study. (+)-epi-Clausenamide showed more potency than (-)-clausenamide on either induction or maintenance of long term potentiation (LTP). Effect of (+)-epi-clausenamide on potentiati...

journal_title：Neuroscience letters

authors： Ning N,Sun J,Du G,Han N,Zhang J,Chen N

更新日期：2012-08-15 00:00:00

abstract：:The efficacy of acetylcholine muscarinic M2 receptor-G protein coupling was investigated in Alzheimer's disease and control neocortical membranes by measuring the effects of MgCl2 and 5'-guanylylimidodiphosphate (Gpp[NH]p) on high-affinity [3H]oxotremorine-M ([3H]OXO-M) binding. MgCl2 gave similar enhancements of [3H]...

journal_title：Neuroscience letters

authors： Hérnandez-Hérnandez A,Adem A,Ravid R,Cowburn RF

更新日期：1995-02-15 00:00:00

abstract：:The mechanisms underlying alterations in brain functions in response to physical exercise are not fully understood. The present study examined the central effect of irisin, a 112 amino acid polypeptide hormone secreted from the skeletal muscle after exercise, on the locomotion in rats. Central administration of irisin...

journal_title：Neuroscience letters

authors： Zhang W,Chang L,Zhang C,Zhang R,Li Z,Chai B,Li J,Chen E,Mulholland M

更新日期：2015-05-19 00:00:00

abstract：:Methamphetamine (METH) is a well-known drug of abuse and neurotoxin that may cause temporary or permanent disturbances in the dopaminergic systems of the brain, predisposing individuals to Parkinsonism. Previously, we have shown that METH causes dopaminergic cell death by increasing the production of reactive oxygen s...

journal_title：Neuroscience letters

authors： Ajjimaporn A,Phansuwan-Pujito P,Ebadi M,Govitrapong P

更新日期：2007-05-23 00:00:00

abstract：:Mild cognitive impairment (MCI) is a nosological entity proposed as an intermediate state between normal aging and dementia. MCI seems to represent an early stage of Alzheimer's disease (AD) and there is a great interest in the relationship between MCI and the progression to AD. Some studies have demonstrated an accum...

journal_title：Neuroscience letters

authors： Padurariu M,Ciobica A,Hritcu L,Stoica B,Bild W,Stefanescu C

更新日期：2010-01-18 00:00:00

abstract：:Ascending thalamo-telencephalic projection systems have been investigated in an urodele, Triturus alpestris, using the horseradish peroxidase technique. Two separate dorsal thalamic projections onto the telencephalon have been identified; one arises from the posterior dorsal thalamus and terminates in the ipsilateral ...

journal_title：Neuroscience letters

authors： Wicht H,Himstedt W

更新日期：1986-07-11 00:00:00

abstract：:Although aging-related alterations in the auditory sensory memory and involuntary change discrimination have been widely studied, it remains controversial whether the mismatch negativity (MMN) or its magnetic counterpart (MMNm) is modulated by physiological aging. This study aimed to examine the effects of aging on mi...

journal_title：Neuroscience letters

authors： Cheng CH,Baillet S,Hsiao FJ,Lin YY

更新日期：2013-06-07 00:00:00

abstract：:Technologies for wireless telecommunication systems using millimeter waves (MMW) will be widely deployed in the near future. Forthcoming applications in this band, especially around 60GHz, are mainly developed for high data-rate local and body-centric telecommunications. At those frequencies, electromagnetic radiation...

journal_title：Neuroscience letters

authors： Haas AJ,Le Page Y,Zhadobov M,Sauleau R,Le Dréan Y

更新日期：2016-04-08 00:00:00

abstract：:Neuroglobin (Ngb) is a novel vertebrate globin expressed principally in neurons. Ngb expression is induced by hypoxia and ischemia, and Ngb protects neurons against these insults. The mechanism of Ngb's protective action is unknown, but its ability to bind NO suggests that NO scavenging might be involved. To test this...

journal_title：Neuroscience letters

authors： Jin K,Mao XO,Xie L,Khan AA,Greenberg DA

更新日期：2008-01-10 00:00:00

abstract：:Immunolocalization of 14-3-3 protein isoforms in relation to Pick bodies in Pick body disease (PBD) brains was investigated. Weakly granular immunoreactivity of 14-3-3 proteins was found in neurons in control subjects and in Pick body disease brains. In addition to this granular immunoreactivity, many Pick bodies were...

journal_title：Neuroscience letters

authors： Umahara T,Uchihara T,Tsuchiya K,Nakamura A,Ikeda K,Iwamoto T,Takasaki M

更新日期：2004-11-23 00:00:00

abstract：:Almost all of the important pathophysiological targets for ethanol in the nervous system appear to be specific membrane proteins involved in signal transduction. In this paper we have examined levels and functionality of the alpha subunit of the Go protein (Goalpha) in cerebral cortex and cerebellum from rats that hav...

journal_title：Neuroscience letters

authors： Guillén A,García-Villafranca J,Mata F,Homburger V,Castro J

更新日期：2003-12-26 00:00:00

abstract：:The nasal cavity of vertebrates contains a variety of xenobiotic metabolizing enzymes that possess a broad range of substrate specificity ranging from metabolism of drugs, carcinogens, and steroid hormones, to dietary components and environmental pollutants. This investigation sought to localize the cellular expressio...

journal_title：Neuroscience letters

authors： Green N,Weech M,Walters E

更新日期：2005-03-03 00:00:00