Increased presence of matrix metalloproteinases 2 and 9 in short- and long-term experimental herpes simplex virus encephalitis.

abstract：:Projection of the vagal C-afferent to the insular cortex was examined in rats. Electrical activation of the C-afferent resulted in two cortical field potentials in the anterior insula. They were independent of each other and neither of them was attributed to the specific thalamic projection. These results imply that v...

journal_title：Neuroscience letters

authors： Ito S

更新日期：1992-12-14 00:00:00

abstract：:This paper reviews the current state of the art in the design of retinal prostheses that hope to restore vision to the blind. The progress and the challenges faced by electronic implants are discussed. Additionally, the emerging technologies in the field are also reviewed. These include optogenetics and chemical inter...

journal_title：Neuroscience letters

authors： Theogarajan L

更新日期：2012-06-25 00:00:00

abstract：:Previously, trophic effects of extracts from whole chick embryos and from innervated muscles on cultured muscle cells were described. The present study demonstrated similar effects of extracts from 10-days denervated chick muscles. Extracts from innervated as well as from denervated muscles exsanguinated in vivo with ...

journal_title：Neuroscience letters

authors： Hooisma J,De Krijger J,De Groot DM,Magchielse T,Muijser H

更新日期：1981-02-23 00:00:00

abstract：:We examined the association between endogenous opioid β-endorphin, cancer progression and pain in a transgenic mouse model of breast cancer, with a rat C3(1) simian virus 40 large tumor antigen fusion gene (C3TAg). C3TAg mice develop ductal epithelial atypia at 8 weeks, progression to intra-epithelial neoplasia at 12 ...

journal_title：Neuroscience letters

authors： Argueta DA,Aich A,Lei J,Kiven S,Nguyen A,Wang Y,Gu J,Zhao W,Gupta K

更新日期：2021-01-23 00:00:00

abstract：:During early postnatal phase, the environment deeply affects developmental trajectories through epigenetic mechanisms that control the levels of key molecules for brain function, such as neurotrophins. Indeed, it has been shown that adverse early experiences induce epigenetic modifications leading to decreased brain d...

journal_title：Neuroscience letters

authors： Branchi I,Karpova NN,D'Andrea I,Castrén E,Alleva E

更新日期：2011-05-20 00:00:00

abstract：:Expression levels of amyloid beta (Abeta)-degrading enzymes, insulin degrading enzyme (IDE) and neprilysin (NEP), were examined in transgenic mice with Alzheimer's disease-like neuropathology. After the development of first Abeta plaques in transgenic mice brain, cortical mRNA and protein levels of IDE were significan...

journal_title：Neuroscience letters

authors： Vepsäläinen S,Hiltunen M,Helisalmi S,Wang J,van Groen T,Tanila H,Soininen H

更新日期：2008-06-20 00:00:00

abstract：:Sleep disturbance is common in chronic post-traumatic stress disorder (PTSD). However, prior work has demonstrated that there are inconsistencies between subjective and objective assessments of sleep disturbance in PTSD. Therefore, we investigated whether subjective or objective sleep assessment has greater clinical u...

journal_title：Neuroscience letters

authors： Tahmasian M,Jamalabadi H,Abedini M,Ghadami MR,Sepehry AA,Knight DC,Khazaie H

更新日期：2017-05-22 00:00:00

abstract：:Cortical depolarizations in the periphery of focal ischemia result in metabolic disturbances which contribute to the progression of the ischemic injury. In this experimental study, therefore, it was examined whether the duration of peri-infarct depolarizations, which reflects the severity of a metabolic mismatch, is d...

journal_title：Neuroscience letters

authors： Mies G

更新日期：1997-01-17 00:00:00

abstract：:The goat milk contains conjugated linoleic acid (CLA), which can influence physical growth and brain development. This study investigated the impact of a diet containing goat milk fat (GMF) on physical parameters of gestating (G) and/or lactating (L) rat dams, and their progeny's physical growth, and anxiety behavior....

journal_title：Neuroscience letters

authors： Soares JK,de Melo AP,Medeiros MC,Queiroga RC,Bomfim MA,Santiago EC,Guedes RC

更新日期：2013-09-27 00:00:00

abstract：:Addicsin is a murine homologue of rat glutamate-transporter-associated protein 3-18 (GTRAP3-18), a putative modulator of neural glutamate-transporter excitatory amino acid carrier 1 (EAAC1). The other molecular functions of addicsin, however, remain largely unknown. We analyzed here the regional and cellular distribut...

journal_title：Neuroscience letters

authors： Inoue K,Akiduki S,Ikemoto MJ

更新日期：2005-10-07 00:00:00

abstract：:The septins, which form a conserved family of cytoskeletal GTP-binding proteins in mammals, comprise stable heteromeric complexes and have diverse roles in protein scaffolding, cytokinesis, vesicle trafficking and plasma membrane integrity following cell division. The goal of this study was to determine the localizati...

journal_title：Neuroscience letters

authors： Hara A,Taguchi A,Niwa M,Aoki H,Yamada Y,Ito H,Nagata K,Kunisada T,Mori H

更新日期：2007-08-23 00:00:00

abstract：:The effect of short-term exercise (15 min step-exercise) on serum brain-derived neurotrophic factor (BDNF) levels was evaluated in healthy human subjects. Results showed a short-term, significant increase in serum BDNF levels after exercise. Intra-individual differences in serum BDNF levels were remarkably small on th...

journal_title：Neuroscience letters

authors： Tang SW,Chu E,Hui T,Helmeste D,Law C

更新日期：2008-01-24 00:00:00

abstract：:Malnutrition affects a large number of children worldwide. Inadequate nutrition during pre- and postnatal period may alter brain development resulting in biochemical, physiological and anatomical changes which in turn could cause behavioral abnormalities. The impairment of the central nervous system following protein ...

journal_title：Neuroscience letters

authors： Bonatto F,Polydoro M,Andrades ME,Conte da Frota ML Jr,Dal-Pizzol F,Rotta LN,Souza DO,Perry ML,Fonseca Moreira JC

更新日期：2006-10-09 00:00:00

abstract：:The three tracers horseradish peroxidase (HRP), 4',6-diamidino-2-phenylindol-2HCl (DAPI) and Fast Blue (FB) differ in retrograde labeling of striato-nigral neurons. After a 24 h survival, injection of DAPI into the ventral tegmentum labeled numerous cells throughout the neostriatum, whereas an identical amount of HRP ...

journal_title：Neuroscience letters

authors： Frotscher M,Wagner A,Misgeld U

更新日期：1983-07-29 00:00:00

abstract：:Distributions of 25 motor axons to 60 intrafusal muscle fibers of 10 poles of monkey spindle were reconstructed from serial 1 micron thick transverse sections of lumbrical muscles. About 44% of motor axons co-innervated two or more types of intrafusal fiber. The (dynamic) bag1 fiber shared motor innervation with the (...

journal_title：Neuroscience letters

authors： Kucera J

更新日期：1985-01-07 00:00:00

abstract：:Microelectrode recordings from the somata of rat dorsal root ganglion (DRG) cells were used to correlate their electrophysiological characteristics with sensitivity to locally applied capsaicin. Of the 80 cells tested, 17 responded to capsaicin by a rapid depolarization. These cells had low axonal conduction velocitie...

journal_title：Neuroscience letters

authors： Heyman I,Rang HP

更新日期：1985-05-01 00:00:00

abstract：:Consummatory successive negative contrast (cSNC) occurs when animals exposed to an unexpected downshift from a high palatable reward (e.g., 32% sucrose solution) to a less preferred one (e.g., 4% sucrose solution) show an abrupt and transient suppression of the consummatory response, compared with control animals that...

journal_title：Neuroscience letters

authors： Annicchiarico I,Cuenya L

更新日期：2018-09-25 00:00:00

abstract：:This study analyses the finger force sharing using power grip task with adapted experimental conditions. This paradigm limits as much as possible the external constraints when the Index (I), Middle (M), Ring (R) and Little (L) fingers act simultaneously: the thumb did not oppose the other fingers and no secondary mome...

journal_title：Neuroscience letters

authors： Vigouroux L,Rossi J,Foissac M,Grélot L,Berton E

更新日期：2011-10-31 00:00:00

abstract：:Oxytoxin (OT) promotes social behavior and reduces anxiety. A great number of studies suggest that OT plays a role in learning and memory processes in animals and humans. Fear memories are rendered labile and prone to modification after reactivation and a restabilization and reconsolidation process is necessary for fu...

journal_title：Neuroscience letters

authors： Hou Y,Zhao L,Zhang G,Ding L

更新日期：2015-05-06 00:00:00

abstract：:We developed a novel procedure for efficient mutagenesis of zebrafish using a DNA cross-linking agent 4,5',8-trimethylpsoralen (TMP), which is known to frequently induce small deletions in Escherichia coli and Caenorhabditis elegans. A specific-locus test and pilot screenings indicated that the TMP mutagenesis procedu...

journal_title：Neuroscience letters

authors： Ando H,Mishina M

更新日期：1998-03-13 00:00:00

abstract：:The effect of 5-hydroxytryptamine on the spontaneous activity of neurons of the subthalamic nucleus was examined by recording the extracellular unitary activity in an in vitro slice preparation. The most frequent response to 5-hydroxytryptamine (84% of 57 neurons tested) was an increase (twofold of basal at 10 microM)...

journal_title：Neuroscience letters

authors： Flores G,Rosales MG,Hernández S,Sierra A,Aceves J

更新日期：1995-06-02 00:00:00

abstract：:This event-related functional Magnetic Resonance Imaging study examined the differential neural activities associated with a Risky-Gains task in 18 healthy individuals of high (n=9) or low (n=9) impulsiveness, according to their scores on the Barratt Impulsiveness Scale (BIS). The neural activities of people belonging...

journal_title：Neuroscience letters

authors： Lee TM,Chan CC,Han SH,Leung AW,Fox PT,Gao JH

更新日期：2008-06-20 00:00:00

abstract：:The activities of monoamine oxidase (MAO)-A and -B in subcellular fractions of bovine retina were determined using serotonin and beta-phenylethylamine, respectively, as substrates. The subcellular fractions were a P1 fraction containing photoreceptor cell synaptosomes and a P2 fraction enriched with small synaptosomes...

journal_title：Neuroscience letters

authors： Sparks DL,Thomas TN,Buckholtz NS

更新日期：1981-01-20 00:00:00

abstract：:Recently, a series of both non-coding (intronic) and coding (exonic) mutations in the tau gene have been linked to a family of autosomal dominant dementias referred to as frontotemporal dementia-17. While linkage analysis has demonstrated that these mutations segregate with disease in affected families, it is unclear ...

journal_title：Neuroscience letters

authors： Jicha GA,Rockwood JM,Berenfeld B,Hutton M,Davies P

更新日期：1999-02-05 00:00:00

abstract：:It has recently been shown that noise can improve the detection of stimuli in several sensory modalities. We herein investigated whether visual contrast detection sensitivity can be improved by adding a certain amount of noise. The contrast detection thresholds of a light changing brightness periodically were measured...

journal_title：Neuroscience letters

authors： Sasaki H,Todorokihara M,Ishida T,Miyachi J,Kitamura T,Aoki R

更新日期：2006-11-13 00:00:00

abstract：:Activation of the μ-opioid receptor (MOR) and noradrenaline reuptake inhibition (NRI) are well recognized as analgesic principles in acute and chronic pain indications. The novel analgesic tapentadol combines MOR agonism and NRI in a single molecule. The present study used OPRM1 (MOR) knockout (KO) mice to determine t...

journal_title：Neuroscience letters

authors： Kögel B,De Vry J,Tzschentke TM,Christoph T

更新日期：2011-03-17 00:00:00

abstract：:Alzheimer disease (AD) is the most common type of dementia, and is currently incurable. The efficacy of existing treatments for AD such as acetylcholinesterase inhibitors is limited to symptom improvement. Research on disease-modifying therapies (DMTs) has conventionally focused on amelioration of CNS pathogenesis. Tw...

journal_title：Neuroscience letters

authors： Shozawa H,Oguchi T,Tsuji M,Yano S,Kiuchi Y,Ono K

更新日期：2018-06-11 00:00:00

abstract：:The alternation of sounds in the left and right ears induces motion perception of a static visual stimulus (SIVM: Sound-Induced Visual Motion). In this case, binaural cues were of considerable benefit in perceiving locations and movements of the sounds. The present study investigated how a spectral cue - another impor...

journal_title：Neuroscience letters

authors： Teramoto W,Manaka Y,Hidaka S,Sugita Y,Miyauchi R,Sakamoto S,Gyoba J,Iwaya Y,Suzuki Y

更新日期：2010-08-02 00:00:00

abstract：:kappa-Opioid receptors were radiolabelled with the peptides [125I]dynorphin(1-8) and [3H]dynorphin(1-8) or with [3H]etorphine on guinea pig forebrain and cerebellar sections and visualized by quantitative autoradiography. All three radioligands yielded similar patterns of kappa-receptor localization. However, quantita...

journal_title：Neuroscience letters

authors： Sharif NA,Hunter JC,Hill RG,Hughes J

更新日期：1988-04-12 00:00:00

abstract：:The act of tasting is the product of inseparable integrative behavior consisting of multi-sensory processing and orolingual motor coordination. Often tasting-induced brain activity is looked at in a reductionist manner as a set of isolated components. However, brain activity as a whole during tasting may not simply be...

journal_title：Neuroscience letters

authors： Okamoto M,Dan H,Clowney L,Yamaguchi Y,Dan I

更新日期：2009-02-20 00:00:00