Monamine oxidase activity in bovine retina: subcellular distribution and drug sensitivities.

Abstract:

:The activities of monoamine oxidase (MAO)-A and -B in subcellular fractions of bovine retina were determined using serotonin and beta-phenylethylamine, respectively, as substrates. The subcellular fractions were a P1 fraction containing photoreceptor cell synaptosomes and a P2 fraction enriched with small synaptosomes derived from the inner plexiform layer. MAO activities in the homogenate and P1 fraction were similar and lower than those in the P2 fraction for both MAO-A and -B. The activity of MAO-B was greater than that of MAO-A in all fractions, but the relative distribution of MAO-A and -B did not change in the different fractions. Studies using various MAO inhibitors showed effects which were generally similar to those seen in brain. These results provide further support for the localization of terminals of retinal monamine-containing neurons to the inner plexiform layer and suggest that pharmacological modification of MAO activity in the retina could play an important role in retinal function via changes in monoamine metabolism.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Sparks DL,Thomas TN,Buckholtz NS

doi

10.1016/0304-3940(81)90382-7

subject

Has Abstract

pub_date

1981-01-20 00:00:00

pages

201-6

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(81)90382-7

journal_volume

21

pub_type

杂志文章
  • Different growth patterns of two adjacent glomeruli responsible for sex-pheromone processing during postembryonic development of the cockroach Periplaneta americana.

    abstract::In many insect species, sex pheromone is processed by specific, enlarged glomeruli in the antennal lobes of males. In the male American cockroach, two closely located glomeruli (A and B) are responsible for processing the major pheromone components (periplanone-A and -B, respectively), and these collectively form the ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2009.07.012

    authors: Nishino H,Yoritsune A,Mizunami M

    更新日期:2009-10-25 00:00:00

  • Sex and regional differences in effects of chronic intermittent ethanol exposure on subsequent excitotoxic challenges in hippocampal slice cultures.

    abstract::The organotypic hippocampal slice culture technique was used to study how the effects of repeated ethanol withdrawal might differ between males and females at the cellular level, including potential modulation of subsequent insults. A chronic intermittent ethanol (CIE) exposure paradigm was employed, with 3 days of ex...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2013.05.011

    authors: Walls SA,Rosenwasser AM,Devaud LL

    更新日期:2013-08-29 00:00:00

  • Serotoninergic endings on VIP-neurons in the suprachiasmatic nucleus and on ACTH-neurons in the arcuate nucleus of the rat hypothalamus. A combination of high resolution autoradiography and electron microscopic immunocytochemistry.

    abstract::A combination of immunocytochemistry with transmitter specific autoradiography at the electron microscopic level was used to identify vasoactive intestinal polypeptide (VIP)- or ACTH-containing neurons and serotoninergic nerve terminals in the suprachiasmatic (SCN) and arcuate nuclei (AN). We observed nerve terminals ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(84)90068-5

    authors: Kiss J,Léránth C,Halász B

    更新日期:1984-02-10 00:00:00

  • Feedback about isometric force production yields more random variations.

    abstract::We investigated the relation between visual feedback and the degree of structure versus randomness in the variability of single-digit, isometric force output. Participants were instructed to maintain a constant level of force during the presence or absence of visual feedback about force output. The structure of force ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.02.002

    authors: Athreya DN,Van Orden G,Riley MA

    更新日期:2012-03-28 00:00:00

  • The organisation of fibres within the rat basis pedunculi.

    abstract::The organisation of corticofugal fibres within the basis pedunculi of rats was studied using wheat germ agglutinin-horseradish peroxidase as an orthograde tracer. Following cortical injections, labelled fibres were distributed within the cerebral peduncle in an orderly way. Fibres which originate from cells in the fro...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90139-x

    authors: Glickstein M,Kralj-Hans I,Legg C,Mercier B,Ramna-Rayan M,Vaudano E

    更新日期:1992-01-20 00:00:00

  • Hypoxia induces activation of a N-methyl-D-aspartate glutamate receptor-protein kinase C pathway in the dorsocaudal brainstem of the conscious rat.

    abstract::To study in vivo phosphorylation of N-methyl-D-aspartate (NMDA) glutamate receptors and the recruitment of protein kinase C isoforms during acute hypoxia, dorsocaudal brainstem lysates were harvested from conscious rats exposed to either room air or hypoxia (10% O2 for 5 and 15 min). Increased phosphorylation of the N...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00887-3

    authors: Simakajornboon N,Gozal E,Gozal YM,Gozal D

    更新日期:2000-01-07 00:00:00

  • RET-RGS, a retina-specific regulator of G-protein signaling, is located in synaptic regions of the rat retina.

    abstract::RGS (regulators of G protein signaling) proteins negatively regulate the alpha subunit of G proteins by accelerating their intrinsic GTPase activity. In a previous work, we reported the cloning of a cDNA encoding for a new RGS protein, RET-RGS. We showed that it is specifically expressed in the retina, notably by phot...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00423-1

    authors: Faurobert E,Scotti A,Hurley JB,Chabre M

    更新日期:1999-07-02 00:00:00

  • Effects of mechanical vibration of the foot sole and ankle tendons on cutaneomuscular responses in man.

    abstract::The modulation of cutaneomuscular responses in response to mechanical vibration applied to the foot sole and to the ankle tendons was established in ten healthy subjects. The effects of mechanical vibration applied to the skin adjacent to the tibialis anterior (TA) and Achilles tendons were examined in two subjects. W...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2013.04.042

    authors: Smith AC,Mummidisetty CK,Rymer WZ,Knikou M

    更新日期:2013-06-17 00:00:00

  • Increased density of galanin binding sites in the dorsal raphe in a genetic rat model of depression.

    abstract::The Flinders Sensitive Line rats showed an increased immobility response by 104% (P<0.01) in the forced swim test with respect to the Flinders Resistant Line rats (control). The Flinders Sensitive Line rats also had an increase of [(125)I]galanin (porcine) binding in the dorsal raphe (55+/-3.3 fmol/mg protein) with re...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)02446-6

    authors: Bellido I,Díaz-Cabiale Z,Jiménez-Vasquez PA,Andbjer B,Mathé AA,Fuxe K

    更新日期:2002-01-11 00:00:00

  • Expression of preproenkephalin mRNA in rat superior cervical ganglion during postnatal development.

    abstract::The number of principal neurons in the rat superior cervical ganglion (SCG) exhibiting enkephalin-peptide immunoreactivity is reported to be limited. To better determine the degree of enkephalinergic phenotype in sympathetic neurons, sections of SCGs from rats aged newborn to adult were processed for in situ hybridiza...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90521-5

    authors: Greif KF

    更新日期:1994-10-24 00:00:00

  • Amburoside A, a glucoside from Amburanacearensis, protects mesencephalic cells against 6-hydroxydopamine-induced neurotoxicity.

    abstract::This study evaluates the potential neuroprotective properties of amburoside A, a glucoside isolated from Amburana cearensis, on rat mesencephalic cell cultures exposure to the neurotoxin 6-hydroxydopamine (6-OHDA). The parameters determined were cell viability by the 3[4,5-dimethylthiazole-2-il]-2,5-diphenyltetrazoliu...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2005.06.034

    authors: Leal LK,Nobre Júnior HV,Cunha GM,Moraes MO,Pessoa C,Oliveira RA,Silveira ER,Canuto KM,Viana GS

    更新日期:2005-11-11 00:00:00

  • Butyrate, neuroepigenetics and the gut microbiome: Can a high fiber diet improve brain health?

    abstract::As interest in the gut microbiome has grown in recent years, attention has turned to the impact of our diet on our brain. The benefits of a high fiber diet in the colon have been well documented in epidemiological studies, but its potential impact on the brain has largely been understudied. Here, we will review eviden...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.neulet.2016.02.009

    authors: Bourassa MW,Alim I,Bultman SJ,Ratan RR

    更新日期:2016-06-20 00:00:00

  • Involvement of the septum in the regulation of paraventricular vasopressin neurons by the subfornical organ in the rat.

    abstract::Extracellular recordings were obtained from 58 phasically active neurosecretory neurons in the hypothalamic paraventricular nucleus (PVN) of urethane-anesthetized male rats. Of these PVN neurons, 39 exhibited an increase and 11 displayed a reduction in ongoing activity following electrical stimulation of the subfornic...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(88)90058-4

    authors: Tanaka J,Saito H,Seto K

    更新日期:1988-10-05 00:00:00

  • Olfactory deprivation enhances normal spine loss in the olfactory bulb of developing ferrets.

    abstract::Ferrets show a sensitive phase in their postnatal development during which they can become imprinted to food odors. At the same time the number of granule cell spines in the olfactory bulb reaches a maximum, declining significantly thereafter. In ferrets, exposed continuously to saturated levels of geraniol odor in th...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(85)90350-7

    authors: Apfelbach R,Weiler E

    更新日期:1985-12-04 00:00:00

  • Developmental changes in 5-hydroxytryptamine-induced rhythmic activity in the spinal cord of rat fetuses in vitro.

    abstract::The roles played by glycine- and glutamate-mediated synaptic transmission in the generation of 5-hydroxytryptamine (5-HT)-induced rhythmic activity were examined in isolated spinal cord preparations from fetal rats. Bath application of 5-HT (0.1-30 microM) evoked rhythmic activity in lumbar ventral roots at and after ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)01913-9

    authors: Nakayama K,Nishimaru H,Kudo N

    更新日期:2001-07-06 00:00:00

  • Analysis of PLA2G6 gene mutation in sporadic early-onset parkinsonism patients from Chinese population.

    abstract::Recent studies have shown that PLA2G6 is a causative gene for PARK14-linked autosomal recessive early-onset complicated dystonia-parkinsonism, early-onset parkinsonism with frontotemporal dementia and autosomal recessive early-onset Parkinsonism without added complicated clinical features. In order to investigate the ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.02.078

    authors: Tian JY,Tang BS,Shi CH,Lv ZY,Li K,Yu RL,Shen L,Yan XX,Guo JF

    更新日期:2012-04-18 00:00:00

  • Reduction in pineal N-acetyltransferase activity and pineal and serum melatonin levels in rats after their exposure to red light at night.

    abstract::Pineal gland N-acetyltransferase (NAT) activity and pineal and serum levels of melatonin declined linearly in albino rats exposed to different irradiances (low, 170 microW/cm2; moderate, 420 microW/cm2; high, 1040 microW/cm2) red light during the middle of the night. High intensity red light (1040 microW/cm2) was as e...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(93)90346-m

    authors: Sun JH,Yaga K,Reiter RJ,Garza M,Manchester LC,Tan DX,Poeggeler B

    更新日期:1993-01-04 00:00:00

  • Presence of the pineal hormone melatonin in rat cochlea: its variations with lighting conditions.

    abstract::Within the normal inner ear, there are elements that belong to the immune system. Different inner ear disorders can be explained by autoimmune mechanisms, affecting both humoral and cellular immunity. Melatonin, the principal hormone of the pineal gland, modulates the immune system and extensively participates in the ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)00844-6

    authors: Lopez-Gonzalez MA,Guerrero JM,Delgado F

    更新日期:1997-11-28 00:00:00

  • Anticipatory postural adjustments in a bimanual load-lifting task in children with Duchenne muscular dystrophy.

    abstract::We investigated the consequences of a progressive damage to the muscular system on the organization of anticipatory postural adjustments (APA) in children with Duchenne muscular dystrophy (DMD). We used a bimanual load-lifting task requiring the stabilization of the forearm position despite its voluntary or imposed un...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2006.04.054

    authors: Jover M,Schmitz C,Bosdure E,Chabrol B,Assaiante C

    更新日期:2006-08-07 00:00:00

  • Blood flow dependent duration of cortical depolarizations in the periphery of focal ischemia of rat brain.

    abstract::Cortical depolarizations in the periphery of focal ischemia result in metabolic disturbances which contribute to the progression of the ischemic injury. In this experimental study, therefore, it was examined whether the duration of peri-infarct depolarizations, which reflects the severity of a metabolic mismatch, is d...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(96)13317-6

    authors: Mies G

    更新日期:1997-01-17 00:00:00

  • The KPNB3 locus is associated with schizophrenia.

    abstract::Seven single nucleotide polymorphisms (SNPs) present on 13q32 were detected among 124 British family trios consisting of fathers, mothers and affected offspring with schizophrenia. The transmission disequilibrium test (TDT) demonstrated that of these 7 SNPs, rs626716, a T to C base change at the KPNB3 locus, was the o...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.07.049

    authors: Wei J,Hemmings GP

    更新日期:2004-09-30 00:00:00

  • Regional differences in the distribution of norepinephrine and epinephrine in human cerebral cortex: a neurochemical study using HPLC and electrochemical detection.

    abstract::We performed neurochemical quantitation of the catecholamines dopamine (DA), norepinephrine (NE) and epinephrine (E) and their major metabolites 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) in 22 cortical regions of 6 postmortem human brains. Stati...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90422-9

    authors: Herregodts P,Michotte Y,Ebinger G

    更新日期:1989-04-10 00:00:00

  • Functional studies of single-site variants in the calmodulin-binding domain of RC3/neurogranin in Xenopus oocytes.

    abstract::Single-site variants in the calmodulin-binding domain of RC3/neurogranin were heterologously expressed in Xenopus oocytes to examine their effects on serotonin-evoked currents. RC3 variants serine36 -->alanine (Ser36-->Ala), serine36-->glycine (Ser36-->Gly), and phenylalanine37-->tryptophan (Phe37-->Trp), which bind c...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(96)13203-1

    authors: Watson JB,Margulies JE,Coulter PM 2nd,Gerendasy DD,Sutcliffe JG,Cohen RW

    更新日期:1996-11-29 00:00:00

  • Duration of untreated illness as a key to early intervention in schizophrenia: A review.

    abstract::The first psychotic episode is classically viewed as a critical period which management is important in determining the long-term outcome of the schizophrenia (SCZ). For this reason, the duration of untreated illness (DUI), defined as the interval between the onset of the psychiatric disorder and the administration of...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.neulet.2016.10.003

    authors: Murru A,Carpiniello B

    更新日期:2018-03-16 00:00:00

  • Prenatal ethanol exposure reduces parvalbumin-immunoreactive GABAergic neuronal number in the adult rat cingulate cortex.

    abstract::The effect of prenatal ethanol exposure on the number of parvalbumin-immunoreactive (PA+) GABAergic neurons in the adult rat anterior cingulate cortex was determined. Pregnant Long-Evans rats were maintained on one of three diets throughout gestation: an ethanol-containing liquid diet, a similar, control liquid diet w...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(98)00378-4

    authors: Moore DB,Quintero MA,Ruygrok AC,Walker DW,Heaton MB

    更新日期:1998-06-12 00:00:00

  • Observing shadow motions: resonant activity within the observer's motor system?

    abstract::Several studies have demonstrated that the human motor cortex is activated by the mere observation of actions performed by others. In the present study, we explored whether the perception of 'impoverished motion stimuli', such as shadow animations, is sufficient to activate motor areas. To do so, transcranial magnetic...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2009.06.055

    authors: Alaerts K,Van Aggelpoel T,Swinnen SP,Wenderoth N

    更新日期:2009-09-25 00:00:00

  • Opposite effects of cyclohexyladenosine and theophylline on hypoxic damage in cultured neurons.

    abstract::To study the central effects of adenosine on hypoxia, the influence of treatment by the A1 receptor agonist cyclohexyladenosine (1 microM) or by the antagonist theophylline (10 microM) was tested on cell damage in a model of neuronal culture. Whereas theophylline enhanced cell injury induced by 8 h hypoxia, cyclohexyl...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)91092-8

    authors: Daval JL,Nicolas F

    更新日期:1994-07-04 00:00:00

  • Depression of the firing of rat cerebral cortical neurons by 2-azido analogues of adenine nucleotides.

    abstract::Iontophoretically applied 2-azido photoaffinity analogues of adenosine 5'-triphosphate (ATP) and adenosine 5'-monophosphate (AMP) have been tested on rat cerebral cortical neurons. 2-Azido-AMP and 2-azido-ATP had a powerful depressant action on the spontaneous firing of cortical neurons. Both compounds were equipotent...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(81)90058-6

    authors: Phillis JW

    更新日期:1981-01-01 00:00:00

  • Glycogen synthase kinase-3beta is associated with Parkinson's disease.

    abstract::We immunohistochemically examined the expression of glycogen synthase kinase-3beta (GSK-3beta) in the brains of Parkinson's disease (PD) patients. GSK-3beta was localized in punctate structures in the cytosol of subsets of neurons in the midbrain and upper pons. GSK-3beta was also localized in Lewy bodies (LBs) as was...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.10.104

    authors: Nagao M,Hayashi H

    更新日期:2009-01-09 00:00:00

  • Morphology of single afferents of the saccular macula in cats.

    abstract::The morphology of single saccular afferents was studied by the intracellular horseradish peroxidase (HRP) method. Four neurons were sufficiently stained to allow reconstruction of their axonal arborizations. The main axon of these neurons bifurcated into an ascending and a descending branch at the level of the lateral...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)00944-0

    authors: Imagawa M,Graf W,Sato H,Suwa H,Isu N,Izumi R,Uchino Y

    更新日期:1998-01-16 00:00:00