The organisation of fibres within the rat basis pedunculi.

abstract：:The prenatal development of axonal connections in the rat olfactory system was studied using DiI. On day 16 (E16), the olfactory and vomeronasal nerves extended from the olfactory epithelia to the olfactory bulb (OB), the terminal nerve to the telencephalic septum, while axons of mitral and tufted cells reached the an...

journal_title：Neuroscience letters

authors： Marchand R,Bélanger MC

更新日期：1991-08-19 00:00:00

abstract：:The nitric oxide synthase (NOS) inhibitor L-nitroarginine methyl ester has been found to exhibit antinociceptive activity in a rat model of pain [Kitto, K.F. et al., Neurosci. Lett., 148 (1992) 1-5; Lee, J.H. et al., NeuroReport, 3 (1992) 841-844; Moore, P.K. et al., Br. J. Pharmacol., 102 (1991) 198-202]. We investig...

journal_title：Neuroscience letters

authors： Lam HH,Hanley DF,Trapp BD,Saito S,Raja S,Dawson TM,Yamaguchi H

更新日期：1996-06-07 00:00:00

abstract：:Protein synthesis is required for long-lasting synaptic plasticity. We examined the time-dependent changes in protein expression that occurred in the hippocampus during synaptic plasticity using two-dimensional gel electrophoresis followed by mass spectrometry. The levels of 15 proteins were significantly changed in m...

journal_title：Neuroscience letters

authors： Matsuura K,Nakamura-Hirota T,Takano M,Otani M,Kadoyama K,Matsuyama S

更新日期：2013-10-25 00:00:00

abstract：:Autosomal-dominant familial amyotrophic lateral sclerosis (FALS) is associated with mutation in the gene that encodes Cu/Zn superoxide dismutase (SOD1). We identified a novel missense mutation of SOD-1 (Cys6Gly) in exon 1 in a Japanese woman and her family. The illness showed rapid progression similarly to the FALS wi...

journal_title：Neuroscience letters

authors： Kohno S,Takahashi Y,Miyajima H,Serizawa M,Mizoguchi K

更新日期：1999-12-03 00:00:00

abstract：:For the first time, a review article focuses exclusively on the role of the protein kinase CK2 in mono- and poly-nucleated mammalian skeletal muscle cells. While CK2, a pleiotropic serine/threonine kinase was originally thought to phosphorylate mainly casein, later evidence found glycogen phosphorylase and glycogen sy...

journal_title：Neuroscience letters

authors： Hashemolhosseini S

更新日期：2020-06-11 00:00:00

abstract：:Unilateral movements are enabled through a distributed network of motor cortical areas but the relative contribution from the parts of this network is largely unknown. Failure of this network potentially results in mirror activation of the primary motor cortex (M1) ipsilateral to the intended movement. Here we tested ...

journal_title：Neuroscience letters

authors： Cincotta M,Borgheresi A,Balestrieri F,Giovannelli F,Rossi S,Ragazzoni A,Zaccara G,Ziemann U

更新日期：2004-09-02 00:00:00

abstract：:Probiotics participate actively in the neuropsychiatric disorders. However, their roles on ischemic stroke remain unclear. This study aims to determine whether Clostridium butyricum (C. butyricum) could attenuate cerebral ischemia/reperfusion (I/R) injury and its possible mechanisms. Male ICR mice were intragastricall...

journal_title：Neuroscience letters

authors： Sun J,Ling Z,Wang F,Chen W,Li H,Jin J,Zhang H,Pang M,Yu J,Liu J

更新日期：2016-02-02 00:00:00

abstract：:There is increasing evidence that sleep may be involved in memory consolidation. However, there remain comparatively few studies that have explored the relationship between sleep and memory reconsolidation. At present study, we tested the effects of rapid eye movement sleep deprivation (RSD) on the reconsolidation of ...

journal_title：Neuroscience letters

authors： Tian S,Huang F,Li P,Ouyang X,Li Z,Deng H,Yang Y

更新日期：2009-09-29 00:00:00

abstract：:Local cerebral glucose utilization (LCGU) was measured during spontaneous waking and slow wave sleep (SWS) by an adaptation of the [14C]deoxyglucose method to the free moving cat. In awake animals heterogeneous rates of LCGU were observed throughout the brain with values extending from 8 mumol x 100 g-1 x min-1 for wh...

journal_title：Neuroscience letters

authors： Petitjean F,Seguin S,Des Rosiers MH,Salvert D,Buda C,Janin M,Debilly G,Jouvet M,Bobillier P

更新日期：1982-09-20 00:00:00

abstract：:The heptadecapeptide histogranin, synthesized by adrenal chromaffin cells, is implicated in the analgesia produced by transplanting chromaffin cells into the spinal cord, including block of hyperalgesia mediated by NMDA-subtype glutamate receptors. To examine the neurophysiological basis for this analgesia, we applied...

journal_title：Neuroscience letters

authors： Hentall ID,Hargraves WA,Sagen J

更新日期：2007-05-23 00:00:00

abstract：:Amyloid precursor protein 17-mer peptide (APP 17-mer peptide) is an active fragment of amyloid precursor protein (APP) in the nervous system that mediates various neuronal activities and functions. Estrogen deprivation during menopause disproportionately increases the risk of many neurodegenerative diseases, including...

journal_title：Neuroscience letters

authors： Meng Y,Wang R,Yang F,Ji ZJ,Fang L,Sheng SL

更新日期：2010-01-14 00:00:00

abstract：:kappa-Opioid receptors were radiolabelled with the peptides [125I]dynorphin(1-8) and [3H]dynorphin(1-8) or with [3H]etorphine on guinea pig forebrain and cerebellar sections and visualized by quantitative autoradiography. All three radioligands yielded similar patterns of kappa-receptor localization. However, quantita...

journal_title：Neuroscience letters

authors： Sharif NA,Hunter JC,Hill RG,Hughes J

更新日期：1988-04-12 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1), an insulinotropic peptide secreted from enteroendocrine cells, has been known to have a neuroprotective effect. However, it is not fully understood the intracellular mediator of GLP-1 signaling in neuronal cells. In the present study, we examined the change in intracellular signaling o...

journal_title：Neuroscience letters

authors： Nakajima S,Numakawa T,Adachi N,Yoon HS,Odaka H,Ooshima Y,Kunugi H

更新日期：2016-03-11 00:00:00

abstract：:Synaptotagmin I (Syt I), a possible Ca(2+) sensor for neurotransmitter release, was suggested to be involved in neurite outgrowth of chick dorsal root ganglion (DRG) neurons, based on introduction of the antibody against the C2A domain into cells via mechanical lesions. Recently, however, the functional block antibody...

journal_title：Neuroscience letters

authors： Fukuda M,Mikoshiba K

更新日期：2000-12-01 00:00:00

abstract：:After traumatic brain injury (TBI), the primary insult is followed by a cascade of secondary events which lead to enlargement of the primary lesion and are potentially amenable to therapeutic intervention. Lisuride is a dopaminergic agonist with additional serotoninergic, adrenergic, and glutamate antagonistic propert...

journal_title：Neuroscience letters

authors： Zweckberger K,Simunovic F,Kiening KL,Unterberg AW,Sakowitz OW

更新日期：2011-07-25 00:00:00

abstract：:Alcohol abuse and anxiety disorders often occur concurrently, but their underlying cellular mechanisms remain unclear. N-methyl-D-aspartic acid receptors (NMDARs) have recently received attention from those interested in the neurobiology of anxiety. A chronic alcohol exposure rat model (28 consecutive days of 20% alco...

journal_title：Neuroscience letters

authors： Yuanyuan J,Junyan Z,Cuola D,Jingjing C,Yuhui S,Dan X,Wei D,Yongsheng Z

更新日期：2018-11-01 00:00:00

abstract：:Glucose is an important metabolic factor controlling feeding behavior. There is evidence that physiologically relevant glucose sensors reside in the caudal hindbrain. The area postrema (AP) in particular, which has been characterized as a receptive site for the anorectic hormone amylin, may monitor blood glucose level...

journal_title：Neuroscience letters

authors： Riediger T,Schmid HA,Lutz TA,Simon E

更新日期：2002-08-09 00:00:00

abstract：:Size-sieved stem cells (SSCs) derived from human bone marrow have the ability to differentiate into bone, fat and cartilage. SSCs can differentiate into active neural cells after exposure to antioxidant agents. The aim of the present study is to understand if SSCs can be stimulated to differentiate into neurons in res...

journal_title：Neuroscience letters

authors： Tzeng SF,Tsai MJ,Hung SC,Cheng H

更新日期：2004-08-26 00:00:00

abstract：:Amyloid beta (A beta) is a normal proteolytic fragment of a large precursor protein (beta PP) which undergoes altered conformation, leading to fibril formation. Two main beta PP processing pathways have been described, and we are now reporting the characterization of a third beta PP pathway. A membrane-associated 16 k...

journal_title：Neuroscience letters

authors： Ghiso J,Gardella JE,Liem L,Gorevic PD,Frangione B

更新日期：1994-04-25 00:00:00

abstract：:It has been known that ethanol causes neuronal cell death through oxidative stress. Ethanol itself and reactive oxygen species (ROS) produced by ethanol modulate intracellular signaling pathways including mitogen-activated protein kinase (MAPK) cascades. This study was conducted to examine the impact of ethanol on MAP...

journal_title：Neuroscience letters

authors： Ku BM,Lee YK,Jeong JY,Mun J,Han JY,Roh GS,Kim HJ,Cho GJ,Choi WS,Yi GS,Kang SS

更新日期：2007-05-23 00:00:00

abstract：:Nitric oxide (NO) from endothelial or neuronal NO synthases (eNOS or nNOS) may contribute both to the cerebrovascular responses to oxygen and potentially to the peroxynitrite-mediated toxic effects of hyperbaric oxygen (HBO(2)) on the central nervous system (CNS O(2) toxicity). In mice lacking eNOS or nNOS (-/-), regi...

journal_title：Neuroscience letters

authors： Demchenko IT,Atochin DN,Boso AE,Astern J,Huang PL,Piantadosi CA

更新日期：2003-06-19 00:00:00

abstract：:An anti-Fos protein antiserum was used to elucidate the diurnal expression of Fos protein in the normal and degenerate rd/rd mice retina. We have found that Fos expression is stimulated in cells of both inner nuclear layer (INL) and ganglion cell layer (GCL) at the onset of light period and reaches its maximum after 2...

journal_title：Neuroscience letters

authors： Huerta JJ,Llamosas MM,Cernuda-Cernuda R,García-Fernández JM

更新日期：1997-09-05 00:00:00

abstract：:Herpes simplex virus encephalitis (HSVE) causes elevated morbidity and mortality despite antiviral treatment. Virus-independent mechanisms may perpetuate brain damage. Matrix metalloproteinases (MMPs) target extracellular matrix components. This study describes the protein and mRNA expression of MMP2 and MMP9 in exper...

journal_title：Neuroscience letters

authors： Martínez-Torres FJ,Wagner S,Haas J,Kehm R,Sellner J,Hacke W,Meyding-Lamadé U

更新日期：2004-09-30 00:00:00

abstract：:Cortical cells in primary culture contain active proteolytic enzymes capable of cleaving nociceptin/orphanin FQ (N/OFQ) and dynorphins to shorter, bioactive fragments. Cells were divided into subpopulations (neurons, astrocytes and oligodendrocytes), and the metabolic pathways in particular populations of the cells we...

journal_title：Neuroscience letters

authors： Suder P,Bogusiewicz A,Rolka K,Laidler P,Kotlinska J,Silberring J

更新日期：2003-09-18 00:00:00

abstract：:Harmonically rich sounds have been shown to be processed more efficiently by the human brain compared to single sinusoidal tones. To control for stimulus complexity as a potentially confounding factor, tones and equally complex spectrally rotated sounds, have been used in the present study to investigate the role of t...

journal_title：Neuroscience letters

authors： Christmann CA,Lachmann T,Berti S

更新日期：2014-10-03 00:00:00

abstract：:Tenascin-R (TN-R) is a neural specific protein and an important molecule involved in inhibition of axonal regeneration after spinal cord injury (SCI). Here we report on rabbit-derived TN-R polyclonal antibody, which acts as a TN-R antagonist with high titer and high specificity, promoted neurite outgrowth and sproutin...

journal_title：Neuroscience letters

authors： You J,Hong SQ,Zhang MY,Zhao HL,Liu TZ,Zhou HL,Cai YQ,Xu ZM,Guo Y,Jiang XD,Xu RX

更新日期：2012-09-13 00:00:00

abstract：BACKGROUND:Perinatal hypoxic-ischemic insult is considered a major contributor to child mortality and morbidity and leads to neurological deficits in newborn infants. There has been a lack of promising neurotherapeutic interventions for hypoxic-ischemic brain damage (HIBD) for clinical application in infants. The prese...

journal_title：Neuroscience letters

authors： Zhu H,Qiao L,Sun Y,Yin L,Huang L,Jiang L,Li J

更新日期：2018-04-23 00:00:00

abstract：:We evaluated the effect of cabergoline on superoxide anion production by rat microglial cells using a 2-methyl-6-(p-methoxyphenyl)-3,7-dihydroimidazo[1, 2-a]pyrazin-3-one-dependent chemiluminescence assay. Cabergoline dose-dependently inhibited superoxide anion production by microglial cells stimulated with phorbol my...

journal_title：Neuroscience letters

authors： Yoshida T,Tanaka M,Suzuki Y,Sohmiya M,Okamoto K

更新日期：2002-09-13 00:00:00

abstract：:The hippocampus is a brain structure specifically vulnerable to short periods of transient cerebral ischemia, and which displays delayed neuronal necrosis. Protein ubiquitination is a posttranslational modification of proteins and an important factor in heat shock response and a regulator of ATP-dependent protein degr...

journal_title：Neuroscience letters

authors： Magnusson K,Wieloch T

更新日期：1989-01-30 00:00:00

abstract：:The study examined whether the generation of the forward propulsive force (PF) during gait initiation resulted mainly from the electromyogram activity of stance ankle plantar flexor muscles (APF) which 'push' on the ground as is generally claimed in the literature. Six unilateral above-knee amputees performed a specif...

journal_title：Neuroscience letters

authors： Michel V,Do MC

更新日期：2002-06-07 00:00:00