Involvement of the human dorsal premotor cortex in unimanual motor control: an interference approach using transcranial magnetic stimulation.

abstract：:Micro traumatic brain injury (TBI) is the most common type of brain injury, but the mechanisms underlying it are poorly understood. Aquaporin-4 (AQP4) is a water channel expressed in astrocyte end-feet, which plays an important role in brain edema. However, little is known about the role of AQP4 in micro TBI. Here, we...

journal_title：Neuroscience letters

authors： Liang F,Luo C,Xu G,Su F,He X,Long S,Ren H,Liu Y,Feng Y,Pei Z

更新日期：2015-06-26 00:00:00

abstract：:The reversible specific binding of [3H]diazepam was observed by a radioligand method in homogenates of cultured cells of mouse glioblastoma. It was characterized by an equilibrium dissociation constant Kd = 91 +/- 5 nM and the number of maximal binding sites (Bmax) of 1006 +/- 100 fmol/mg protein. The half-saturation ...

journal_title：Neuroscience letters

authors： Zlobina GP,Kondakova LI,Khalansky AS

更新日期：1984-12-21 00:00:00

abstract：:Chronic morphine administration induces neural plasticity followed by withdraw. And clinic observation indicates that obvious cognitive deficits are found during withdrawal. However, current neural substrates that regulate dysfunction in withdrawal are unknown. In our studies, chronic morphine administration was used ...

journal_title：Neuroscience letters

authors： Niu H,Zhang G,Li H,Zhang Q,Li T,Ding S,Wang L,Zhang Z,Qiao Y,Hu M

更新日期：2017-02-15 00:00:00

abstract：:The number of active cells in each synchronous firing event in a set of 10 neurosecretory cells in the silkmoth Bombyx mori was estimated from the amplitude and waveform of compound action potentials. One to 10 cells discharged an action potential within a period of 30 ms and one to two or nine to 10 units became acti...

journal_title：Neuroscience letters

authors： Ichikawa T,Imafuku Y,Tawada K

更新日期：1999-04-02 00:00:00

abstract：:There is little information available on the mechanisms underlying the neuroprotective actions of the organoselenium compound ebselen. In this study, we sought to determine the relationship between alterations in the expression of Bcl-2 and Bax proteins and intracellular levels of calcium and the protective effects of...

journal_title：Neuroscience letters

authors： Xu JH,Hu HT,Liu Y,Qian YH,Liu ZH,Tan QR,Zhang ZJ

更新日期：2006-05-22 00:00:00

abstract：:Both substance P (SP)- and epinephrine-containing neurons in the rostral ventrolateral medulla have been thought to play a role in regulating vasomotor tone. The combination of retrograde transport of a fluorescent dye (Fast Blue) and immunofluorescent staining for SP- and phenylethanolamine-N-methyltransferase (PNMT)...

journal_title：Neuroscience letters

authors： Lorenz RG,Saper CB,Wong DL,Ciaranello RD,Loewy AD

更新日期：1985-04-19 00:00:00

abstract：:In rodents the vomeronasal system plays an important role in modulating the hypothalamic control of gonadotropin secretion. It is accepted that the anatomical pathways by which the vomeronasal organ influences the neuroendocrine aspects of the reproductive behavior involves a polysynaptic system, including the accesso...

journal_title：Neuroscience letters

authors： Larriva-Sahd J,Rondán A,Orozco-Estévez H,Sánchez-Robles MR

更新日期：1993-11-26 00:00:00

abstract：:Glutamate receptor interacting protein (GRIP) is a member of the PDZ domain-containing protein family that is localized in the postsynaptic density area. This protein has been reported to interact specifically with the C-termini of AMPA-selective glutamate receptor channel subunits, GluRalpha2 and GluRalpha3 through i...

journal_title：Neuroscience letters

authors： Yamazaki M,Fukaya M,Abe M,Ikeno K,Kakizaki T,Watanabe M,Sakimura K

更新日期：2001-05-18 00:00:00

abstract：:In mammals, methyl-CpG binding proteins play a significant role in the control of gene expression through their association with chromatin-remodeling complexes. Mutations in the gene coding for methyl-CpG-binding protein 2 (MECP2) cause Rett syndrome and have also been reported in a number of X-linked mental retardati...

journal_title：Neuroscience letters

authors： dos Santos JM,Abdalla CB,Campos M Jr,Santos-Rebouças CB,Pimentel MM

更新日期：2005-04-29 00:00:00

abstract：:The angular distribution of mitotic spindle fibers has been studied in the telencephalic ventricular zone (VZ) of mouse embryos and has been found to be monophasic and invariant during the early cortical histogenesis both in the normal and in a reeler embryo. This observation suggests that the orientation of mitotic s...

journal_title：Neuroscience letters

authors： Landrieu P,Goffinet A

更新日期：1979-06-01 00:00:00

abstract：:The dopamine transporter (DAT1) gene has been implicated in the pathogenesis of many neuropsychiatric disorders, including schizophrenia. The present study aimed to investigate association of the DAT1 gene polymorphisms with schizophrenia in a Han Chinese population. Two single nucleotide polymorphisms (SNPs) in the D...

journal_title：Neuroscience letters

authors： Zheng C,Shen Y,Xu Q

更新日期：2012-04-04 00:00:00

abstract：:Plasma corticosterone has been correlated with the susceptibility to animal hypnosis in male rabbits. Subjects (Ss) were considered susceptible when mean hypnosis duration was above 30 sec or when initial duration (duration of trial 1) was greater than 0. A positive significant correlation was found between mean and i...

journal_title：Neuroscience letters

authors： Carli G,Farabollini F,di Prisco CL

更新日期：1979-03-01 00:00:00

abstract：:GABAergic modulation of enkephalin, substance P and glutamic acid decarboxylase (GAD67) gene expression and the alterations induced by dopamine receptor blockade were studied in the rat striatum. Following subchronic treatment with the GABA-A agonist muscimol, the GABA-B agonist baclofen or the GABA transaminase inhib...

journal_title：Neuroscience letters

authors： Jolkkonen J,Jenner P,Marsden CD

更新日期：1994-10-24 00:00:00

abstract：:The cognitive deficits observed in schizophrenia are considered a core feature of the disease. Neuregulin-1 is a risk gene for schizophrenia that is involved in many neurodevelopmental and synaptic plasticity-related processes relevant to schizophrenia. Here, we have utilized a rat model (Nrg1(Tn)), which is hypomorph...

journal_title：Neuroscience letters

authors： Taylor AR,Taylor SB,Koenig JI

更新日期：2012-12-07 00:00:00

abstract：:Prolyl endopeptidase (PEP; EC 3.4.21.26) cleaves the Pro-Arg bond of arginine-vasopressin (AVP). This study investigated the effects of PEP inhibitors, 1-[1-(benzyloxycarbonyl)-L-prolyl]prolinal (Z-Pro-prolinal) and 1-[3-(2-indanylacetyl)-L-thioprolyl]pyrrolidine (Z-321), on the AVP content in the septum of rats. Oral...

journal_title：Neuroscience letters

authors： Miura N,Shibata S,Watanabe S

更新日期：1995-08-18 00:00:00

abstract：:The action of glycine (Gly) on rat cortical neurons was studied. Gly, iontophoretically applied, hyperpolarized the membrane potential, blocked the firing rate and decreased the amplitude of EPSP-IPSP sequences. Generally the membrane resistance during the aminoacid ejection decreased. The role of Gly in the rat corti...

journal_title：Neuroscience letters

authors： Bernardi G,Cherubini E,Marciani MG,Stanzione P

更新日期：1979-05-01 00:00:00

abstract：:Little is known about the effect of wnt-3a on motor nerve function and its specific molecular mechanisms after spinal cord injury (SCI). This study demonstrates that the downregulated expression levels of caspases-3, caspases-9 and chondroitin sulfate proteoglycan (CSPG) proteins and number of proportion of transferas...

journal_title：Neuroscience letters

authors： Gao K,Niu J,Dang X

更新日期：2020-10-15 00:00:00

abstract：:The ability of three nitric oxide (NO) donor compounds to modify ligand binding to kainate receptors was studied in tissue from human adult autopsy brains. Binding of [3H]kainic acid (5 nM) was measured in frontal cortex membranes made from Brodmann area 8 (BA 8) and autoradiographically using sections of frontal cort...

journal_title：Neuroscience letters

authors： Lees RD,Slater P,D'Souza SW

更新日期：1997-09-19 00:00:00

abstract：:Cortical spreading depression (SD) may produce some symptoms of the aura of classical migraine but it is less probable that it can account for the headache. The aversiveness of SD was examined in unanesthetized rats. In Exp. 1, rats with implanted cortical cannulae were confined in the dark compartment of the step-thr...

journal_title：Neuroscience letters

authors： Koroleva VI,Bures J

更新日期：1993-01-12 00:00:00

abstract：:Stereotaxic injections of ibotenic acid (IBO) and kainic acid (KA) into either the dorsal hippocampus or the lateral cerebroventricle were performed in order to determine the relative potencies of the drugs and the vulnerability of different hippocampal cell types to their neurotoxic action, IBO was found to be approx...

journal_title：Neuroscience letters

authors： Köhler C,Schwarcz R,Fuxe K

更新日期：1979-12-01 00:00:00

abstract：:In this study the effect of memantine, an antagonist at the N-methyl-D-aspartate receptor, on spatial learning deficit and on neuronal damage following transient cerebral ischemia was evaluated. Global ischemia was induced by four-vessel-occlusion (4VO) for 20 min in rats. Memantine was administered 20 min before indu...

journal_title：Neuroscience letters

authors： Block F,Schwarz M

更新日期：1996-04-12 00:00:00

abstract：:Although synaptically released, vesicular Zn(2+) has been proposed to play a neuromodulatory or neuronal signaling role at the mossy fiber-CA3 synapse, Zn(2+) release remains controversial, especially when detected using fluorescent imaging. In the present study, we investigated synaptically released Zn(2+) at the mos...

journal_title：Neuroscience letters

authors： Bastian C,Li YV

更新日期：2007-05-29 00:00:00

abstract：:We evaluated whether brain-derived neurotrophic factor (BDNF) can stimulate choline acetyltransferase (ChAT) activity in the septo-hippocampal pathway of ethylcholine mustard aziridinium (AF64A) and non-AF64A-treated rats. Rats received either AF64A (1.5 nmol/ ventricle) or a sham (non-AF64A-treated) injection into th...

journal_title：Neuroscience letters

authors： Willson CA,Hanin I

更新日期：1997-07-04 00:00:00

abstract：:The non-invasive imaging technique of diffusion tensor imaging (DTI) has been used to investigate the microstructural properties of white matter (WM). The present study investigated whether individual differences in the WM structure of normal subjects as measured by fractional anisotropy (FA) values correlate with cog...

journal_title：Neuroscience letters

authors： Takahashi M,Iwamoto K,Fukatsu H,Naganawa S,Iidaka T,Ozaki N

更新日期：2010-06-21 00:00:00

abstract：:The effect of various ionic solutions microinjected into the nucleus tractus solitarii (NTS) on blood pressure, heart rate and respiration rate was investigated in urethane-anesthetized rats. Unilateral microinjection of solutions containing NaCl (154 mM), NaCl (154 mM) and KCl (2.8 mM) or NaNO3 (154 mM) into a restri...

journal_title：Neuroscience letters

authors： Lukovic L,de Jong W

更新日期：1990-03-02 00:00:00

abstract：:Compared to other M(1) muscarinic acetylcholine receptor (M(1) mAChR) agonists, xanomeline demonstrates both reversible and persistent modes of binding to the receptor. In our study, we investigated the long-term consequences of brief incubation of Chinese hamster ovary cells expressing M(1) mAChR (M(1)-CHO) with low ...

journal_title：Neuroscience letters

authors： De Lorme KC,Sikorski KL,Grant MK,El-Fakahany EE

更新日期：2006-12-13 00:00:00

abstract：:Angiotensin II-sensitive neurons in the brain of spontaneously hypertensive rats (SHR-sp) and of Wistar Kyoto rats (WKY) treated with the angiotensin-converting enzyme inhibitor Captopril were investigated for possible differences at receptor sites. Furthermore, the concentrations of angiotensinogen and renin were mea...

journal_title：Neuroscience letters

authors： Felix D,Schelling P

更新日期：1982-12-23 00:00:00

abstract：:Pharmacologic blockade of excitatory amino acid receptors, especially the N-methyl-D-aspartate-preferring subclass of glutamate receptors, has been shown to reduce neuronal damage in models of global cerebral ischemia followed by reperfusion. The pharmacologic blockade at the NMDA receptor attenuates infarct size foll...

journal_title：Neuroscience letters

authors： Roman R,Bartkowski H,Simon R

更新日期：1989-09-25 00:00:00

abstract：:Pineal gland N-acetyltransferase (NAT) activity and pineal and serum levels of melatonin declined linearly in albino rats exposed to different irradiances (low, 170 microW/cm2; moderate, 420 microW/cm2; high, 1040 microW/cm2) red light during the middle of the night. High intensity red light (1040 microW/cm2) was as e...

journal_title：Neuroscience letters

authors： Sun JH,Yaga K,Reiter RJ,Garza M,Manchester LC,Tan DX,Poeggeler B

更新日期：1993-01-04 00:00:00

abstract：:Norepinephrine (NE) has been reported to modulate neuronal excitability and act as endogenous anticonvulsant. In the present study we used NE transporter knock-out mice (NET-KO), which are characterized by high levels of extracellular NE, to investigate the role of endogenous NE in seizure susceptibility. Seizure thre...

journal_title：Neuroscience letters

authors： Kaminski RM,Shippenberg TS,Witkin JM,Rocha BA

更新日期：2005-07-01 00:00:00