Increase in the septal vasopressin content by prolyl endopeptidase inhibitors in rats.

abstract：:In an attempt to understand the change of superoxide dismutase (SOD) in tumor cells by hypoxia and hypoxia-normoxia exposure, the present study performed an in vitro investigation using rat glioma cell line in culture. Hypoxia was induced by an incubation with nitrogen gas for 15 h followed the normoxia exposure with ...

journal_title：Neuroscience letters

authors： Chang CK,Tsai CY,Lin LS,Jou SB,Liao SS,Cheng JT

更新日期：1997-08-29 00:00:00

abstract：:Protein kinase C (PKC) pathway plays important roles in different phenomena in nervous system development. Our previous data demonstrated that phorbol 12-myristate 13-acetate (PMA) treatment, a PKC activator, for 48 h decreases retinal cells proliferation by a mechanism mediated by muscarinic receptor activation, invo...

journal_title：Neuroscience letters

authors： Braga LE,Granja MG,da Silva GM,Giestal-de-Araujo E,dos Santos AA

更新日期：2013-08-29 00:00:00

abstract：:Fatigue of the lumbar extensor muscles has been associated with a degradation of balance, but the mechanism is not well understood. The ankle plays a major role in upright standing, and loss of proprioceptive acuity at the ankle could contribute to a degradation of balance. Therefore, the first objective of this study...

journal_title：Neuroscience letters

authors： Pline KM,Madigan ML,Nussbaum MA,Grange RW

更新日期：2005-12-16 00:00:00

abstract：:The effect of bifemelane hydrochloride (BFH) on the induction of heat shock protein (HSP) 70 and heat shock cognate protein (HSC) 70 mRNAs after transient global ischemia in gerbil brain was investigated by in situ hybridization using cloned cDNA probes selective for each mRNA species. Following 3.5 min of ischemia, H...

journal_title：Neuroscience letters

authors： Aoki M,Abe K,Liu XH,Lee TH,Kato H,Kogure K

更新日期：1993-05-14 00:00:00

abstract：:Oleamide is a recently described lipid, obtained from the cerebrospinal fluid of sleep-deprived cats. It has been observed that oleamide possesses several biological effects, such as sleep induction, and immunological suppression as well as serotonin and gamma-aminobutyric acid receptors activation. In addition, oleam...

journal_title：Neuroscience letters

authors： Murillo-Rodríguez E,Giordano M,Cabeza R,Henriksen SJ,Méndez Díaz M,Navarro L,Prospéro-García O

更新日期：2001-11-02 00:00:00

abstract：:We studied the topographical distribution of laser sensory thresholds on the human hairy skin, using a small laser beam for pinprick and a large beam for warmth sensations. The threshold for pinprick sensation correlated positively with the distance from the brain, suggesting that Adelta nociceptors, the fibers which ...

journal_title：Neuroscience letters

authors： Agostino R,Cruccu G,Iannetti G,Romaniello A,Truini A,Manfredi M

更新日期：2000-05-12 00:00:00

abstract：:Which cognitive processes are reflected by the N400 in ERPs is still controversial. Various recent articles (Lau et al., 2008; Brouwer et al., 2012) have revived the idea that only lexical pre-activation processes (such as automatic spreading activation, ASA) are strongly supported, while post-lexical integrative proc...

journal_title：Neuroscience letters

authors： Steinhauer K,Royle P,Drury JE,Fromont LA

更新日期：2017-06-09 00:00:00

abstract：:This study was designed to assess whether phencyclidine (PCP)-induced head-twitch was antagonized by ritanserin, a selective serotonin (5-HT2) receptor antagonist, in mice and rats to confirm the involvement of 5-hydroxytryptamine (5-HT) neurons in PCP actions in comparison with 5-methoxy-N,N-dimethyltryptamine (5-MeO...

journal_title：Neuroscience letters

authors： Nabeshima T,Ishikawa K,Yamaguchi K,Furukawa H,Kameyama T

更新日期：1987-05-19 00:00:00

abstract：:Dehydroepiandrosterone sulfate (DHEAS) dose-dependently inhibited [3H]norepinephrine (NE) secretion and the corresponding [Ca2+]i rise induced by the nicotinic receptor agonist 1,1-dimethyl-4-phenylpoperazimium (DMPP) in bovine chromaffin cells. DHEAS at 10 microM, the physiological concentration in human serum, signi...

journal_title：Neuroscience letters

authors： Liu PS,Lin MK,Hsieh HL

更新日期：1996-02-09 00:00:00

abstract：:The effects of microiontophoretic application of 5-hydroxytryptamine (5-HT) on the neuronal firing rate of the medial vestibular nucleus (MVN) were studied in anaesthetized rats. Ninety-three % of the units modified their background activity following 5-HT iontophoresis, enhancements of the firing rate being recorded ...

journal_title：Neuroscience letters

authors： Licata F,Li Volsi G,Maugeri G,Santangelo F

更新日期：1993-05-14 00:00:00

abstract：:The present study was designed to determine whether the p53 tumor-suppressor protein is involved in the development of antinociceptive tolerance to morphine. When the doses of morphine (mg/kg per injection) were subcutaneously given into mice as pretreatment twice daily for 2 days (first day (30) and second day (60)),...

journal_title：Neuroscience letters

authors： Tan-No K,Shimoda M,Watanabe K,Nakagawasai O,Niijima F,Kanno S,Ishikawa M,Bakalkin G,Tadano T

更新日期：2009-02-06 00:00:00

abstract：:In this study, we investigated two newly reported polymorphisms in association with late onset Alzheimer's disease (AD) in Chinese. They were a -491 A/T polymorphism in the Apolipoprotein E (APOE) promoter region and a five base pair deletion at exon 18 of alpha2-Macroglobin (A2M). There were 196 AD and 180 normal con...

journal_title：Neuroscience letters

authors： Chen L,Baum L,Ng HK,Chan LY,Sastre I,Artíga MJ,Valdivieso F,Bullido MJ,Chiu HF,Pang CP

更新日期：1999-07-16 00:00:00

abstract：:The mammalian target of rapamycin (mTOR) exerts neuroprotective effects under hypoxic or ischemic conditions. To explore whether mTOR participates in neuroprotective signaling through regulation of hypoxia-inducible factor-1α (HIF-1α), vascular endothelial growth factor (VEGF) and neuronal apoptosis in developing rat ...

journal_title：Neuroscience letters

authors： Chen H,Xiong T,Qu Y,Zhao F,Ferriero D,Mu D

更新日期：2012-01-24 00:00:00

abstract：:Confocal immunohistochemistry shows that neurotrophin-3 (NT-3) and its receptor tropomyosin-related tyrosin kinase C (trkC) are present in both neonatal (P6) and adult (P45) mouse motor nerve terminals in neuromuscular junctions (NMJ) colocalized with several synaptic proteins. NT-3 incubation (1-3h, in the range 10-2...

journal_title：Neuroscience letters

authors： Garcia N,Santafé MM,Tomàs M,Lanuza MA,Besalduch N,Tomàs J

更新日期：2010-04-05 00:00:00

abstract：:The morphology and spatial distribution of terminals emitted by corticothalamic axons originating from the rat motor cortex (as defined by intracortical microstimulations) were studied using Phaseolus vulgaris leucoagglutinin (PHA-L) as an anterograde tracer. After PHA-L injection in the face, forelimb or hindlimb mot...

journal_title：Neuroscience letters

authors： Rouiller EM,Liang FY,Moret V,Wiesendanger M

更新日期：1991-04-15 00:00:00

abstract：:The action of glycine (Gly) on rat cortical neurons was studied. Gly, iontophoretically applied, hyperpolarized the membrane potential, blocked the firing rate and decreased the amplitude of EPSP-IPSP sequences. Generally the membrane resistance during the aminoacid ejection decreased. The role of Gly in the rat corti...

journal_title：Neuroscience letters

authors： Bernardi G,Cherubini E,Marciani MG,Stanzione P

更新日期：1979-05-01 00:00:00

abstract：:Previous studies have shown an association between diabetes mellitus and impairments in learning and memory. These deficits were partially reversed by the use of insulin. Due to the fact that exercise has positive effects on many physiological systems, including the central nervous system, the present study, evaluated...

journal_title：Neuroscience letters

authors： Reisi P,Alaei H,Babri S,Sharifi MR,Mohaddes G

更新日期：2009-05-15 00:00:00

abstract：:This paper presents additional evidence showing the persistent functional deficits in concussed athletes as revealed by altered movement-related cortical potentials (MRCP) preceding whole body postural movements at least 30 days post-injury. Eight student-athletes participated in this study (a) prior to injury; and (b...

journal_title：Neuroscience letters

authors： Slobounov S,Sebastianelli W,Moss R

更新日期：2005-08-05 00:00:00

abstract：:Recent evidence indicates that alterations in brain polyamine metabolism may be critical for nerve cell survival after a free radical initiated neurodegenerative process. It has been shown previously that A beta(1-42) and A beta(25-35) are toxic to neurons through a free radical dependent oxidative mechanism. Treatmen...

journal_title：Neuroscience letters

authors： Yatin SM,Yatin M,Aulick T,Ain KB,Butterfield DA

更新日期：1999-03-19 00:00:00

abstract：:The 22Na+ efflux stimulated by selected agonists of the 4 excitatory amino acid receptors, previously detected in the striatum, has been studied on 22Na+-preloaded slices prepared from 10 major areas of the rat brain. All brain areas were found to be sensitive, albeit to varying extents, to excitatory amino acids. The...

journal_title：Neuroscience letters

authors： Luini A,Goldberg O,Teichberg VI

更新日期：1983-11-11 00:00:00

abstract：:Pitrazepin is a potent new GABA antagonist which differs from bicuculline in its chemical structure and its interaction with both [3H]muscimol and [3H]flunitrazepam binding sites, whereby the potency of pitrazepin in displacing [3H]muscimol exceeds that of bicuculline by at least a factor of 10. In physiological exper...

journal_title：Neuroscience letters

authors： Gähwiler BH,Maurer R,Wüthrich HJ

更新日期：1984-04-06 00:00:00

abstract：:Divalent metals such as cobalt are frequently used by neurophysiologists to prevent synaptic transmission, because they are thought to selectively block presynaptic calcium conductance. Recording intracellularly from hippocampal CA3 pyramidal cells we show that Co2+ (2 mM) is not specific in this action but also dimin...

journal_title：Neuroscience letters

authors： Gerber U,Gähwiler BH

更新日期：1991-12-16 00:00:00

abstract：:Intestinal electric stimulation (IES) has been shown to produce an inhibitory effect on gastric motility and secretion. The possible central mechanism of this entero-gastric inhibitory effect induced by IES is unknown. The objective of this study was to evaluate the effects of various IES on the activity of neurons in...

journal_title：Neuroscience letters

authors： Sun Y,Qin C,Foreman RD,Chen JD

更新日期：2005-09-02 00:00:00

abstract：:Effects of sleep deprivation (SD) on one-trial recognition memory were investigated in rats using either a spontaneous novel-object or object-place recognition test. Rats were allowed to explore a field in which two identical objects were presented. After a delay period, they were placed again in the same field in whi...

journal_title：Neuroscience letters

authors： Ishikawa H,Yamada K,Pavlides C,Ichitani Y

更新日期：2014-09-19 00:00:00

abstract：:The effects of the normotensive, mainly centrally active nitric oxide synthase (NOS) inhibitor 7-nitro indazole and the hypertensive drug NG-nitro-L-arginine, which blocks both the endothelial and the central NOS, have been examined on naloxone-precipitated withdrawal in morphine-dependent rats. Both drugs attenuated ...

journal_title：Neuroscience letters

authors： Cappendijk SL,Duval SY,de Vries R,Dzoljic MR

更新日期：1995-01-02 00:00:00

abstract：:We raised polyclonal antibodies against a gene product responsible for late infantile neuronal ceroid lipofuscinosis (CLN2). By Western blotting, all three antisera recognized the CLN2 protein at approximately 49 kDa in human brain homogenates. Immunohistochemistry using the antisera demonstrated the granular labellin...

journal_title：Neuroscience letters

authors： Oka A,Kurachi Y,Mizuguchi M,Hayashi M,Takashima S

更新日期：1998-11-27 00:00:00

abstract：:Aβ-mediated oxidative stress damage is considered a direct cause of Alzheimer's disease (AD). Therefore, drugs that have been developed to block oxidative stress are considered effective for AD treatment. Isosilybin is a flavonoid compound extracted from Silybum marianum, and it has been confirmed to have many pharmac...

journal_title：Neuroscience letters

authors： Zhou J,Chao G,Li Y,Wu M,Zhong S,Feng Z

更新日期：2016-10-06 00:00:00

abstract：:Previously, we have demonstrated that pressure-ejected application of angiotensin II and losartan, an angiotensin AT1 receptor antagonist, onto some neurons in the anterior hypothalamic area (AHA) of the rat increases and decreases, respectively, the basal firing rate of the neurons. To investigate possible participat...

journal_title：Neuroscience letters

authors： Hagiwara Y,Kubo T

更新日期：2007-04-12 00:00:00

abstract：:The effects of long-term exposure of primary cultured rat dorsal root ganglion (DRG) cells to bradykinin (BK), compared to short-term exposure, were investigated to establish whether BK could induce prostaglandin E2 (PGE2) release from DRG cells. Short-term exposure (30 min) resulted in a small but significant amount ...

journal_title：Neuroscience letters

authors： Inoue A,Iwasa M,Nishikura Y,Ogawa S,Nakasuka A,Nakata Y

更新日期：2006-07-03 00:00:00

abstract：:Aberrant tyrosine transport is a repeated finding in fibroblasts from schizophrenic patients. The transport aberration could lead to disturbances in the dopaminergic and noradrenergic neurotransmitter systems. Tyrosine and tryptophan are the precursors of the neurotransmitters dopamine and serotonin. Disturbed dopamin...

journal_title：Neuroscience letters

authors： Persson ML,Johansson J,Vumma R,Raita J,Bjerkenstedt L,Wiesel FA,Venizelos N

更新日期：2009-06-19 00:00:00