Brain-derived neurotrophic factor induced stimulation of septal choline acetyltransferase activity in ethylcholine mustard aziridinium treated rats.

abstract：:Abnormal myelin gene expression in the central nervous system (CNS) is associated with many mental illnesses, including psychiatric disorders and drug addiction. We have previously shown that prenatal exposure to nicotine, the major psychoactive component in cigarette smoke, alters myelin gene expression in the CNS of...

journal_title：Neuroscience letters

authors： Cao J,Dwyer JB,Gautier NM,Leslie FM,Li MD

更新日期：2013-10-11 00:00:00

abstract：:Using organotypic hippocampal slice cultures we have investigated the actions of Interleukin-1 (IL-1) in a number of injury paradigms. Low concentrations of IL-1 potentiated hypoxia-induced neurodegeneration whilst high concentrations had no effect. In contrast, higher concentrations of IL-1 were strongly neuroprotect...

journal_title：Neuroscience letters

authors： Pringle AK,Niyadurupola N,Johns P,Anthony DC,Iannotti F

更新日期：2001-06-01 00:00:00

abstract：:'Reverspectives' (by artist Patrick Hughes) consist of truncated pyramids with their small faces closer to the viewer, allowing realistic scenes to be painted on them. Because their pictorial perspective reverses the physical depth arrangement, reverspectives provide a bistable paradigm of two radically different, com...

journal_title：Neuroscience letters

authors： Wagner M,Ehrenstein WH,Papathomas TV

更新日期：2009-01-09 00:00:00

abstract：:Mesial temporal lobe epilepsy (MTLE) is a common type of intractable epilepsy characterized by astroglial gliosis. The S100B was viewed as an astrocyte marker and experimental studies indicated that S100B might be involved in the pathophysiology of temporal lobe epilepsy. In this study, we measured plasma S100B levels...

journal_title：Neuroscience letters

authors： Lu C,Li J,Sun W,Feng L,Li L,Liu A,Li J,Mao W,Wei H,Gao L,Zhang X,Huang Z,Meng X,Wang Y

更新日期：2010-10-29 00:00:00

abstract：:Displaced ganglion cells were identified in the carp retina by the retrograde axonal transport of horseradish peroxidase injected into the optic tectum. Cells in the ganglion cell layer were all labelled, while in the amacrine cell layer only 1/4000 cells were labelled. Because of such low population, it is unlikely t...

journal_title：Neuroscience letters

authors： Tachibana M

更新日期：1978-09-01 00:00:00

abstract：:Glycinergic inhibitory neurotransmission plays a pivotal role in the development of neuropathic pain. The glycine concentration in the synaptic cleft is controlled by the glycine transporters GlyT1 and GlyT2. GlyT1 is expressed throughout the central nervous system, while GlyT2 is exclusively located in glycinergic ne...

journal_title：Neuroscience letters

authors： Schlösser L,Barthel F,Brandenburger T,Neumann E,Bauer I,Eulenburg V,Werdehausen R,Hermanns H

更新日期：2015-07-23 00:00:00

abstract：:The effects of electrical stimulation of the central (CE) and basolateral (BL) amygdaloid nuclei on pancreatic exocrine secretion were tested in urethane-anesthetized rats. Electrical stimulation (0.1 mA, 1 ms, 40 Hz) of the CE significantly increased basal and hormone (secretin+cholecystokinin-8)-infused pancreatic e...

journal_title：Neuroscience letters

authors： Hahn SJ,Yoon SH,Sim SS,Rhie DJ,Jo YH,Kim MS

更新日期：1994-03-14 00:00:00

abstract：:The content of the neurosteroids, dehydroepiandrosterone (DHEA) in the brain decreases with aging. Also the oxidative energy metabolism is known to decrease with aging. Hence we examined the effects of treatment with DHEA (0.2 or 1.0 mg/kg body weight for 7 days) on oxidative energy metabolism in brain mitochondria fr...

journal_title：Neuroscience letters

authors： Patel MA,Katyare SS

更新日期：2006-07-10 00:00:00

abstract：:A comparison of the effect of fatigue caused by electrical induction or voluntary contraction on Ia inhibition in human soleus muscle was investigated in fourteen healthy male subjects. The Hoffmann reflex (H reflex) was employed to elucidate the contribution of fatigue induced contraction to the Ia inhibition. A stat...

journal_title：Neuroscience letters

authors： Tsuboi T,Sato T,Egawa K,Miyazaki M

更新日期：1995-09-01 00:00:00

abstract：:The vertebrate retina is known to mediate both visual and non-image-forming photic responses. With the use of statistical analyses of sections immunohistochemically labelled with a polyclonal antiserum against the activated form of protein CREB (p-CREB), a transcription factor which participates in some neural respons...

journal_title：Neuroscience letters

authors： Alvarez-López C,Cernuda-Cernuda R,Paniagua MA,Alvarez-Viejo M,Fernández-López A,García-Fernández JM

更新日期：2004-03-11 00:00:00

abstract：:Nogo-A has been identified as an inhibitory molecule to neurite outgrowth after injury in adult mammalian central nervous system (CNS). The C-terminal fragment of Nogo-A, Nogo-66, inhibits axonal regrowth through NgR1 signaling. Residues 1-32 of Nogo-66 cover two regions that contribute most affinity of Nogo-66 to NgR...

journal_title：Neuroscience letters

authors： Deng Q,Cai W,Li S,Su B

更新日期：2013-03-01 00:00:00

abstract：:A random sample of 60 late-onset Alzheimer's disease (AD) cases from a population-based study were apolipoprotein E (apoE) genotyped and clinically examined with a 3-year interval. The epsilon 4 allele carriers had a significantly lower age of disease onset compared to non-epsilon 4 carriers. However, no significant d...

journal_title：Neuroscience letters

authors： Basun H,Grut M,Winblad B,Lannfelt L

更新日期：1995-01-02 00:00:00

abstract：:The pharmacology of the metabotropic glutamate receptor (mGluR)-mediated potentiation of N-methyl-D-aspartate (NMDA)-evoked depolarisations in the CA1 region of rat hippocampal slices was investigated using an extracellular grease-gap method. The group I and II mGluR agonist (1S,3R)-1-aminocyclopentane-1,3-dicarboxyli...

journal_title：Neuroscience letters

authors： Fitzjohn SM,Irving AJ,Palmer MJ,Harvey J,Lodge D,Collingridge GL

更新日期：1996-01-26 00:00:00

abstract：:Decreased dopamine (DA) release in the hippocampus may be caused by dysfunctional mastication, although the mechanisms involved remain unclear. The present study examined the effects of soft- and hard-food diets on oxidative stress in the brain, and the relationship between these effects and hippocampal DA levels. The...

journal_title：Neuroscience letters

authors： Yoshino F,Yoshida A,Hori N,Ono Y,Kimoto K,Onozuka M,Lee MC

更新日期：2012-02-02 00:00:00

abstract：:Previous studies have shown an association between diabetes mellitus and impairments in learning and memory. These deficits were partially reversed by the use of insulin. Due to the fact that exercise has positive effects on many physiological systems, including the central nervous system, the present study, evaluated...

journal_title：Neuroscience letters

authors： Reisi P,Alaei H,Babri S,Sharifi MR,Mohaddes G

更新日期：2009-05-15 00:00:00

abstract：:The parietal cortex of the human brain plays a unique role in the coordination of movement and in the integration of signals from the other cortices. Because of its extensive connections and involvement in many higher-order cognitive functions, neurodegenerative changes in the parietal lobe are believed to be crucial ...

journal_title：Neuroscience letters

authors： Mills JD,Nalpathamkalam T,Jacobs HI,Janitz C,Merico D,Hu P,Janitz M

更新日期：2013-03-01 00:00:00

abstract：:Tumor cells frequently express the insulin-like growth factor I (IGF-I). Recently we demonstrated that rat glioma cells when transfected with a vector encoding antisense IGF-I cDNA lost tumorigenicity and induced a tumor specific immune response involving CD8+ lymphocytes. Here we show that the cultured transfected ce...

journal_title：Neuroscience letters

authors： Trojan J,Duc HT,Upegui-Gonzalez LC,Hor F,Guo Y,Anthony D,Ilan J

更新日期：1996-07-05 00:00:00

abstract：:It has recently been shown that noise can improve the detection of stimuli in several sensory modalities. We herein investigated whether visual contrast detection sensitivity can be improved by adding a certain amount of noise. The contrast detection thresholds of a light changing brightness periodically were measured...

journal_title：Neuroscience letters

authors： Sasaki H,Todorokihara M,Ishida T,Miyachi J,Kitamura T,Aoki R

更新日期：2006-11-13 00:00:00

abstract：:[3H] Overflow evoked by 5 min supramaximal preganglionic stimulation at 1 pps has been studied in isolated guinea pig superior cervical ganglion preparations preincubated with [3H]choline. At 15 microM norepinephrine (NE) reduced both the [3H]choline overflow and endogenous acetylcholine release by 59.4 and 54.1% resp...

journal_title：Neuroscience letters

authors： Belluzzi O,Travagli RA,Bonifazzi C,Perri V

更新日期：1987-01-02 00:00:00

abstract：:There is little information available on the mechanisms underlying the neuroprotective actions of the organoselenium compound ebselen. In this study, we sought to determine the relationship between alterations in the expression of Bcl-2 and Bax proteins and intracellular levels of calcium and the protective effects of...

journal_title：Neuroscience letters

authors： Xu JH,Hu HT,Liu Y,Qian YH,Liu ZH,Tan QR,Zhang ZJ

更新日期：2006-05-22 00:00:00

abstract：:Neurocalcin, a newly discovered calcium-binding protein belonging to the recoverin-like superfamily, was detected immunohistochemically in tufted cells from the rat olfactory bulb. More precisely, only periglomerular tufted cells and some tufted cells from the external plexiform layer were expressing neurocalcin. West...

journal_title：Neuroscience letters

authors： Bastianelli E,Okazaki K,Hidaka H,Pochet R

更新日期：1993-10-29 00:00:00

abstract：:Dominance hierarchies within social groups determine resource distribution. Resources, such as food and access to mating partners, can act as reinforcers. The present study examined the effect of social rank on access to wheel running-a reinforcing behavior performed by laboratory animals. Mice were identified as domi...

journal_title：Neuroscience letters

authors： Vargas-Pérez H,Sellings L,Grieder T,Díaz JL

更新日期：2009-07-03 00:00:00

abstract：:Discrete brain structures were analysed for gamma-aminobutyric acid (GABA) and vasopressin content in normo- and hypotensive rats treated with the glutamic acid decarboxylase inhibitor, 3-mercaptopropionic acid (MPA) and the GABAA agonist muscimol. In the normotensive group treated with MPA only, the concentration of ...

journal_title：Neuroscience letters

authors： Magnusson A,Höglund U,Sjöquist M

更新日期：1989-07-03 00:00:00

abstract：:Cultures were produced from retinas taken from human foetuses. Specific cells in culture have the capacity to take up exogenous serotonin, which was then visualized by immunofluorescence using an antisera to serotonin. The known serotonergic uptake blocker, chlorimipramine, inhibited the uptake of the amine while benz...

journal_title：Neuroscience letters

authors： Osborne NN,Beaton DW

更新日期：1985-04-09 00:00:00

abstract：:In micturition control, the roles of ionotropic glutamate (iGlu) receptors NMDA and AMPA are well established, whereas little is known about the function of metabotropic glutamate (mGlu) receptors. Since antagonists for mGlu5 receptors are efficacious in animal models of inflammatory and neuropathic pain, we examined ...

journal_title：Neuroscience letters

authors： Hu Y,Dong L,Sun B,Guillon MA,Burbach LR,Nunn PA,Liu X,Vilenski O,Ford AP,Zhong Y,Rong W

更新日期：2009-01-23 00:00:00

abstract：:Normal treatment of rats with monosodium-L-glutamate (MSG) resulted in extensive degeneration of the inner nuclear layer of the retina. The retino-hypothalamic projection was still functional as these rats entrained their circadian food intake rhythm to the light-dark cycle. A normal proportion of dorsal lateral genic...

journal_title：Neuroscience letters

authors： Groos G

更新日期：1981-09-25 00:00:00

abstract：:Interleukin-1 (IL-1) mediates numerous responses on the mouse anterior pituitary cell line AtT-20. We have studied the ligand binding properties of the IL-1 receptors (IL-1R) of the AtT-20 cells and found that they possess 1.5 x 10(3) receptors/cell with a Kd of 0.15 nM for [125I]IL-1 alpha. Using oligonucleotide prim...

journal_title：Neuroscience letters

authors： Bristulf J,Simoncsits A,Bartfai T

更新日期：1991-07-22 00:00:00

abstract：:Most fibres in adult muscles are derived from secondary myotubes which form around an earlier developing population of primary myotubes. We examined embryonic rat IVth lumbrical muscles at a stage when most secondary myotubes were less than 24 h old, in order to study their acquisition of synaptic terminals. Single ne...

journal_title：Neuroscience letters

authors： Duxson MJ,Ross JJ,Harris AJ

更新日期：1986-11-11 00:00:00

abstract：:Employing video-enhanced contrast (VEC) microscopy, we examined whether TAK-029 (GPIIb/IIIa antagonist) inhibits the adhesion of activated platelets to human brain microvascular endothelial cells (HBEC) in vitro. HBECs were cultured on a coverglass and put in the observation chamber of VEC microscopy. Then, activated ...

journal_title：Neuroscience letters

authors： Tanahashi N,Fukuuchi Y,Tomita M,Tomita Y,Inoue K,Satoh H,Abe T

更新日期：2001-03-23 00:00:00

abstract：:Cellular locations, axonal projections, and synaptic effects of inhibitory vestibulocollic (VC) neurons activated by the ampullary nerve of the posterior semicircular canal (PCN) were studied in anesthetized cats. The inhibitory VC neurons were identified by their monosynaptic responses to PCN stimulation and by their...

journal_title：Neuroscience letters

authors： Isu N,Sakuma A,Hiranuma K,Ichikawa T,Uchino Y

更新日期：1990-11-13 00:00:00