Abstract:
:Normal treatment of rats with monosodium-L-glutamate (MSG) resulted in extensive degeneration of the inner nuclear layer of the retina. The retino-hypothalamic projection was still functional as these rats entrained their circadian food intake rhythm to the light-dark cycle. A normal proportion of dorsal lateral geniculate nucleus (LGNd) cells in MSG rats responded to visual stimulation. The response pattern, latency and variability of LGNd cells at different times (3-18 months) after treatment were comparable to those of normal rats. These results demonstrate the MSG-induced retinal damage does not lead to blindness in the rat. The similarity in pathophysiology between MSG lesioned rats and animals exposed to constant illumination is discussed.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Groos Gdoi
10.1016/0304-3940(81)90407-9subject
Has Abstractpub_date
1981-09-25 00:00:00pages
293-7issue
3eissn
0304-3940issn
1872-7972pii
0304-3940(81)90407-9journal_volume
25pub_type
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1996-10-18 00:00:00
abstract::This article has been withdrawn at the request of the Editor-in-Chief. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal. ...
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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pub_type: 杂志文章
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