Quantitative evaluation of alpha- and beta-adrenoceptor modulation of [3H]choline release in guinea pig superior cervical ganglia.

abstract：:The sexual axis of rats can be rendered photoresponsive by testosterone implants. We have studied in these conditions whether rat pars tuberalis (PT) melatonin receptor density would be decreased after exposure to short photoperiod (SP) like as observed in long day seasonal breeders. The answer is no, but we observed ...

journal_title：Neuroscience letters

authors： Recio J,Pévet P,Míguez JM,Masson-Pévet M

更新日期：1996-08-16 00:00:00

abstract：:To study in vivo phosphorylation of N-methyl-D-aspartate (NMDA) glutamate receptors and the recruitment of protein kinase C isoforms during acute hypoxia, dorsocaudal brainstem lysates were harvested from conscious rats exposed to either room air or hypoxia (10% O2 for 5 and 15 min). Increased phosphorylation of the N...

journal_title：Neuroscience letters

authors： Simakajornboon N,Gozal E,Gozal YM,Gozal D

更新日期：2000-01-07 00:00:00

abstract：:Recombinant gamma-aminobutyric acid (GABA(A)) receptor channels containing alpha1beta2gamma2-subunits were transiently expressed in HEK293 cells. Modulation by diazepam (DZ) was investigated using the patch-clamp technique with a device for ultra-fast solution exchange. GABA activated Cl(-)-currents were potentiated w...

journal_title：Neuroscience letters

authors： Krampfl K,Lepier A,Jahn K,Franke C,Bufler J

更新日期：1998-11-13 00:00:00

abstract：:Effects of near-ultraviolet (UV-A; 325-390 nm, peak at 365 nm) light on the activity of the pineal serotonin N-acetyltransferase (NAT; a penultimate and key regulatory enzyme in melatonin biosynthesis) were examined in rats. Acute exposure of dark-adapted animals to UV-A radiation produced a marked suppression of NAT ...

journal_title：Neuroscience letters

authors： Zawilska JB,Rosiak J,Nowak JZ

更新日期：1998-02-27 00:00:00

abstract：:Decreased expression of NT-3 mRNA in the sciatic nerve and leg muscles of streptozotocin (STZ)-diabetic rats has been associated with the pathogenesis of diabetic neuropathy. The aim of this study was to determine whether STZ-induced diabetes also affects the expression of NT-3 mRNA in the central and peripheral proje...

journal_title：Neuroscience letters

authors： Cai F,Tomlinson DR,Fernyhough P

更新日期：1999-03-26 00:00:00

abstract：:Brachial plexus avulsion (BPA) is one of the major injuries in motor vehicle accidents and may result in neuropathic pain. Accumulating evidence suggests that 30-80% of BPA developed neuropathic pain in human. In our study, complete brachial plexus avulsion (C5-T1) rats model leads to the results that 37.5% of rats ha...

journal_title：Neuroscience letters

authors： Wang L,Yuzhou L,Yingjie Z,Jie L,Xin Z

更新日期：2015-03-04 00:00:00

abstract：:The opioid peptide dynorphin A(1-8) (1 micron) increased acetylcholine release from the Torpedo electric organ by approximately twofold. This effect was reversed by the opiate antagonist naloxone. The effect of Dyn A(1-8) on acetylcholine release was found to vary in magnitude with the seasons of the year, with maxima...

journal_title：Neuroscience letters

authors： Oron L,Sarne Y,Michaelson DM

更新日期：1991-04-29 00:00:00

abstract：:Quantitative neurophysiological studies have identified the presence of at least two spinal neuron populations (ABRUPT and SUSTAINED) which are excited by the noxious visceral stimulus colorectal distension (CRD). The present study examined the effects of acute colorectal inflammation on the activity of dorsal horn ne...

journal_title：Neuroscience letters

authors： Ness TJ,Gebhart GF

更新日期：2000-03-10 00:00:00

abstract：:Mouse acetylcholine receptors (AChRs) consisting of either the embryonic form (2 alpha, 1 beta, 1 delta and 1 gamma) or the adult form (2 alpha, 1 beta, 1 delta and 1 epsilon) were expressed in Xenopus laevis oocytes. As expected, the single channel conductance was approximately 52 pS and the exponential decay time co...

journal_title：Neuroscience letters

authors： Liu E,Hamill OP,Salpeter MM

更新日期：1994-06-06 00:00:00

abstract：:Circadian rhythms of pineal melatonin release were measured in freely moving pigeons (Columba livia) by in vivo microdialysis. The birds were placed in light-dark cycles with 12 h of light and 12 h of darkness (LD 12:12) or continuous dim light (LLdim) after LD 12:12. Although the level of melatonin was various, daily...

journal_title：Neuroscience letters

authors： Hasegawa M,Ebihara S

更新日期：1992-12-14 00:00:00

abstract：:Unilateral movements are enabled through a distributed network of motor cortical areas but the relative contribution from the parts of this network is largely unknown. Failure of this network potentially results in mirror activation of the primary motor cortex (M1) ipsilateral to the intended movement. Here we tested ...

journal_title：Neuroscience letters

authors： Cincotta M,Borgheresi A,Balestrieri F,Giovannelli F,Rossi S,Ragazzoni A,Zaccara G,Ziemann U

更新日期：2004-09-02 00:00:00

abstract：:Deficit in balance control is a common and often an initial disabling symptom of multiple sclerosis (MS). The aim of the study was to investigate the organization of anticipatory and compensatory postural adjustments in individuals with MS dealing with external perturbations. Ten individuals with MS and ten age-and-ge...

journal_title：Neuroscience letters

authors： Aruin AS,Kanekar N,Lee YJ

更新日期：2015-03-30 00:00:00

abstract：:Global cerebral ischemia-reperfusion (GCI/R) may occur after any of several clinical conditions such as cardiac arrest and anesthetic accident. Some dopamine receptor agonists possess neuroprotective effects. However, some of them may produce side effects during treatment. Piribedil, which is a dopamine D2/D3 receptor...

journal_title：Neuroscience letters

authors： Wang W,Liu L,Chen C,Jiang P,Zhang T

更新日期：2018-09-25 00:00:00

abstract：:Five picrotoxinin analogues were examined on GABA-gated chloride channels of an identifiable cockroach (Periplaneta americana) motor neurone (Df). Substitution of the bridgehead hydroxyl at the C-6 position of the picrotoxinin molecule by a fluorine atom (fluoropicrotoxinin) had little effect, whereas acetylation of t...

journal_title：Neuroscience letters

authors： Anthony NM,Holyoke CW Jr,Sattelle DB

更新日期：1994-04-25 00:00:00

abstract：:Ovariectomy in the rat abolishes alpha-bungarotoxin (alpha-BTX) binding within the suprachiasmatic nucleus (SCN), a putative circadian pacemaker, and markedly reduces cholinergic activation of SCN cells. Circadian rhythms of running wheel activity were monitored continuously in intact male and female and chronically o...

journal_title：Neuroscience letters

authors： Mistlberger RE,Rusak B

更新日期：1986-12-23 00:00:00

abstract：:1-methyl-4-phenylpyridinium ion (MPP(+)) has been shown to selectively inhibit mitochondrial function and induce a parkinsonism-like syndrome. MPP(+) stimulates the production of reactive oxygen species (ROS) and induces cell death in vitro. In this study, we investigated the protective effects of okadaic acid on MPP(...

journal_title：Neuroscience letters

authors： Ahn KH,Kim YS,Kim SY,Huh Y,Park C,Jeong JW

更新日期：2009-01-09 00:00:00

abstract：:125I-Staphylococcal protein A was used to visualize immunoreactive cell antigen in rat brain and pituitary by autoradiography. Autoradiograms of rat brain sections generated with 125I-protein A were clear and showed low background signals. We were able to visualize neural structures containing tyrosine hydroxylase or ...

journal_title：Neuroscience letters

authors： Correa FM,Guilhaume SS,Saavedra JM

更新日期：1988-06-29 00:00:00

abstract：:Emerging evidence suggests that the SNP rs2736990 of SNCA is a susceptibility factor for idiopathic Parkinson's disease (PD) in different populations, but the studies which examined the association have provided inconsistent results. Therefore, we performed a meta-analysis of some case-control studies to obtain a more...

journal_title：Neuroscience letters

authors： Fang J,Hou B,Liu H,Zhang X,Wang J,Zhou C,Xie A

更新日期：2017-09-29 00:00:00

abstract：:Dysregulated brain glucose metabolism and lactate accumulation are seen following traumatic brain injury (TBI). The underlying molecular mechanism is poorly understood. Pyruvate dehydrogenase (PDH), the rate-limiting enzyme coupling cytosolic glycolysis to mitochondrial citric acid cycle, plays a critical role in main...

journal_title：Neuroscience letters

authors： Xing G,Ren M,Watson WD,O'Neill JT,Verma A

更新日期：2009-04-17 00:00:00

abstract：:Samples of human cerebral cortex were stained immunocytochemically for tyrosine hydroxylase (TH) and gamma-aminobutyric acid (GABA). TH-positive neurons were in small number and predominated in the deep infragranular layers V-VI contrasting with numerous GABA-positive neurons scattered in all layers. Co-localization o...

journal_title：Neuroscience letters

authors： Trottier S,Geffard M,Evrard B

更新日期：1989-11-20 00:00:00

abstract：:Cerebral ischemia-reperfusion (I/R)-induced brain tissue injury is a major obstacle for acute stroke management. Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) is reported to play a critical role in the regulation of myocardial or hepatic I/R injury. However, its role in cerebral I/R remains elu...

journal_title：Neuroscience letters

authors： Liu Y,Guo Y

更新日期：2021-01-19 00:00:00

abstract：:In brainstem slices of guinea pigs perfused with artificial cerebro-spinal fluid (ACSF), the discharge of all the spontaneously active neurons of the medial vestibular nucleus (MVN) is regular. It has been reported that prolonged exposure to a low Ca(2+) medium could induce these neurons to fire bursts of spikes. In t...

journal_title：Neuroscience letters

authors： Ris L,Godaux E

更新日期：2001-01-12 00:00:00

abstract：:This article has been withdrawn at the request of the Editor-in-Chief. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal. ...

journal_title：Neuroscience letters

authors： Luo J,Wang Y,Li W,Long L,Cao H

更新日期：2020-06-29 00:00:00

abstract：BACKGROUND:Perinatal hypoxic-ischemic insult is considered a major contributor to child mortality and morbidity and leads to neurological deficits in newborn infants. There has been a lack of promising neurotherapeutic interventions for hypoxic-ischemic brain damage (HIBD) for clinical application in infants. The prese...

journal_title：Neuroscience letters

authors： Zhu H,Qiao L,Sun Y,Yin L,Huang L,Jiang L,Li J

更新日期：2018-04-23 00:00:00

abstract：:In this study, we have investigated the release of immunoreactive interleukin-1 beta (irIL-1 beta) from the rat hypothalamus in vitro. It was found that (1) tissue explants release sizable amounts of irIL-1 beta (ranging from 0.43 to 0.52 pg/mg of wet tissue) in 20 min incubations; (2) basal release in significantly i...

journal_title：Neuroscience letters

authors： Tringali G,Mancuso C,Mirtella A,Pozzoli G,Parente L,Preziosi P,Navarra P

更新日期：1996-11-29 00:00:00

abstract：:Almost all of the important pathophysiological targets for ethanol in the nervous system appear to be specific membrane proteins involved in signal transduction. In this paper we have examined levels and functionality of the alpha subunit of the Go protein (Goalpha) in cerebral cortex and cerebellum from rats that hav...

journal_title：Neuroscience letters

authors： Guillén A,García-Villafranca J,Mata F,Homburger V,Castro J

更新日期：2003-12-26 00:00:00

abstract：:We immunohistochemically investigated the degeneration processes of the nigro-striatal and nigro-amygdaloid pathways and the relationship between the loss of dopaminergic neurons and Lewy bodies (LB) formation in the substantia nigra using 15 autopsied cases of dementia with Lewy bodies (DLB). The number of tyrosine h...

journal_title：Neuroscience letters

authors： Iseki E,Marui W,Yamamoto R,Togo T,Katsuse O,Kato M,Iwatsubo T,Kosaka K,Arai H

更新日期：2005-05-20 00:00:00

abstract：:Chondroitin sulfate/dermatan sulfate (CS/DS) polysaccharides have been reported to play a crucial role in the proliferation and maintenance of neural stem cells (NSCs). However, little is known about the structural changes and functional role of CS/DS chains in the differentiation of NSCs. Western blots of NSCs, neuro...

journal_title：Neuroscience letters

authors： Yamauchi S,Kurosu A,Hitosugi M,Nagai T,Oohira A,Tokudome S

更新日期：2011-04-15 00:00:00

abstract：:The effects of Ga-Al-As diode laser (830 nm, 16.2 mW) irradiation on the distal portion of the processes of cultured murine dorsal root ganglion (DRG) neurons associated with C-fibers were studied by patch-clamp whole-cell recording of membrane potentials at the cell body. The chemical as well as laser light stimulati...

journal_title：Neuroscience letters

authors： Jimbo K,Noda K,Suzuki K,Yoda K

更新日期：1998-01-09 00:00:00

abstract：:This study was designed toinvestigate the efficacy of adenovirus vector-mediated brain-derived neurotrophic factor (BDNF) ex vivo gene transfer to human umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) in a rat sciatic nerve crush injury model. BDNF protein and mRNA expression after infection was checked...

journal_title：Neuroscience letters

authors： Hei WH,Almansoori AA,Sung MA,Ju KW,Seo N,Lee SH,Kim BJ,Kim SM,Jahng JW,He H,Lee JH

更新日期：2017-03-16 00:00:00