The transcription factor CREB is phosphorylated in neurons of the piriform cortex of blind mice in response to illumination of the retina.

abstract：:Microglia, the resident immune cells of the brain, are activated in response to any kind of CNS injury, and their activation is critical for maintaining homeostasis within the CNS. However, during inflammatory conditions, sustained microglial activation results in damage to surrounding neuronal cells. beta-Glucans are...

journal_title：Neuroscience letters

authors： Shah VB,Williams DL,Keshvara L

更新日期：2009-07-24 00:00:00

abstract：:A replication-defective recombinant adenoviral vector containing E. coli lacZ gene was injected into the gastrocnemius muscles of transgenic mice carrying mutant Cu/Zn superoxide dismutase (SOD1) gene and non-transgenic wild-type mice at 40 weeks of age. After 60 and 90 h of the injection, lacZ staining was observed a...

journal_title：Neuroscience letters

authors： Murakami T,Nagano I,Hayashi T,Manabe Y,Shoji M,Setoguchi Y,Abe K

更新日期：2001-08-10 00:00:00

abstract：:Many experimental observations have demonstrated the modulatory role exerted by several neural structures and neurotransmitters on spontaneous and paroxysmal bioelectric activity of the hippocampus. Recently, the control exerted by locus coeruleus (LC) and its noradrenergic (NA) efferent pathway on different experimen...

journal_title：Neuroscience letters

authors： Ferraro G,Sardo P,Sabatino M,Caravaglios G,La Grutta V

更新日期：1994-03-14 00:00:00

abstract：:Cold defense mechanisms in mice are attenuated in the light phase during fasting, resulting in hypothermia. The present study examined whether specific neurons and areas in the SCN are related to the response. Mice were fasted over 47h or remained fed, during which they were placed at 20 or 27°C for 3h in the light or...

journal_title：Neuroscience letters

authors： Uchida Y,Tokizawa K,Nagashima K

更新日期：2014-09-05 00:00:00

abstract：:The effects of methamphetamine (MAP) administration on neurotensin-like immunoreactivity (NTLI) were investigated in the rat brain. A single administration of MAP induced dose-dependent and reversible increases in NTLI in the caudate-putamen, limbic forebrain and midbrain. NTLI in the caudate-putamen, limbic forebrain...

journal_title：Neuroscience letters

authors： Wachi M,Okuda M,Togashi S,Miyashita O,Wakahoi T

更新日期：1987-07-22 00:00:00

abstract：:Alternative cleavage of the amyloid precursor protein (APP) results in generation and secretion of both soluble APP (sAPP) and beta-amyloid (Abeta). Abeta is the main component of the amyloid depositions in the brains of Alzheimer's disease (AD) patients. Using Western blotting, we compared the levels of alpha-secreta...

journal_title：Neuroscience letters

authors： Sennvik K,Fastbom J,Blomberg M,Wahlund LO,Winblad B,Benedikz E

更新日期：2000-01-14 00:00:00

abstract：:To investigate the relationship between apolipoprotein E (APOE) polymorphisms and the severity of traumatic brain injury (TBI) in acute stage in the cohort of mainland Chinese patients. We prospectively identified admissions to the two neurosurgical departments for head injury. A total of 110 subjects with TBI (80 mal...

journal_title：Neuroscience letters

authors： Jiang Y,Sun X,Xia Y,Tang W,Cao Y,Gu Y

更新日期：2006-11-13 00:00:00

abstract：:Activities of motor units of human tibialis anterior muscle were studied when the subject maintained the force of the muscle at a constant level voluntarily. Motor units were classified into two main groups according to their discharge frequencies and their tensions. Those units which were recruited from the beginning...

journal_title：Neuroscience letters

authors： Kato M,Murakami S,Takahashi K,Hirayama H

更新日期：1981-09-01 00:00:00

abstract：:The cells of origin of the brainstem projection to the caudate-putamen (CP) were examined in the albino rat by the use of two fluorescent retrograde tracers. Nuclear yellow was injected into the CP of one hemisphere and granular blue was injected into the contralateral CP. Retrogradely labeled cells were studied in th...

journal_title：Neuroscience letters

authors： Loughlin SE,Fallon JH

更新日期：1982-09-20 00:00:00

abstract：:There is considerable evidence linking both genotype and coagulopathy to vascular complications of traumatic brain injury (TBI) and other cerebral insults. The authors explored a possible connection between the apolipoprotein E (Apo E) genotype, coagulopathy and intravascular microthombosis (IMT) in TBI. The predicted...

journal_title：Neuroscience letters

authors： Stein SC,Graham DI,Chen XH,Dunn L,Smith DH

更新日期：2005-10-14 00:00:00

abstract：:Tinnitus is the perception of sound in the absence of any external auditory stimulus. Based on previous research we have proposed a framework which postulates that the reduction of ongoing inhibitory alpha activity in tinnitus subjects favors a synchronization of neurons in the gamma frequency range while in a resting...

journal_title：Neuroscience letters

authors： Lorenz I,Müller N,Schlee W,Hartmann T,Weisz N

更新日期：2009-04-10 00:00:00

abstract：:Neurons containing the peptide corticotropin-releasing factor (CRF) are thought to play a pivotal role in orchestrating autonomic and behavioral responses to stress. CRF afferents to the thalamus are almost entirely concentrated in the midline nuclei, especially in the paraventricular thalamic nucleus. In chloral hydr...

journal_title：Neuroscience letters

authors： Otake K,Nakamura Y

更新日期：1995-12-01 00:00:00

abstract：:Cholinergic influences on attention are well documented and recent evidence indicates that genetic variation in the alpha4beta2 nicotinic receptor affects attentional networks of the brain. Several behavioral and electrophysiological studies have shown that a common polymorphism in the CHRNA4 gene (rs1044396) affects ...

journal_title：Neuroscience letters

authors： Reinvang I,Lundervold AJ,Rootwelt H,Wehling E,Espeseth T

更新日期：2009-04-10 00:00:00

abstract：:EEG-feedback, also called neurofeedback, is a training procedure aimed at altering brain activity, and is used as a treatment for disorders like Attention Deficit/Hyperactivity Disorder (ADHD). Studies have reported positive effects of neurofeedback on attention and other dependent variables. However, double-blind stu...

journal_title：Neuroscience letters

authors： Logemann HN,Lansbergen MM,Van Os TW,Böcker KB,Kenemans JL

更新日期：2010-07-19 00:00:00

abstract：:The mental rotation (MR) task is defined as a discrimination task between mirror-reversed images involving discrepancy in angular orientation. Various studies have shown that the MR task likely causes mental imagery, that is, visual and/or motor imagery, depending on stimulus types. When figures of rotated hands are p...

journal_title：Neuroscience letters

authors： Meng S,Oi M,Sekiyama K,Saito H

更新日期：2016-08-03 00:00:00

abstract：:The anti-neuroinflammatory effect of Astragaloside IV (ASI) has been reported, but its underlying mechanisms are unclear. This study is further to explore the underlying mechanism of ASI on anti-neuroinflammatory effect in LPS induced microglia cells. The result showed ASI significantly reduced the production of infla...

journal_title：Neuroscience letters

authors： Li C,Yang F,Liu F,Li D,Yang T

更新日期：2018-02-14 00:00:00

abstract：:Attention-deficit/hyperactivity disorder (ADHD) is highly prevalent in children and adolescents and both environmental and genetic factors play major roles. Polyunsaturated fatty acids (PUFAs) are postulated to contribute to the development of the infant brain and an imbalance in these may increase the risk of ADHD. I...

journal_title：Neuroscience letters

authors： Bartl J,Walitza S,Grünblatt E

更新日期：2014-01-24 00:00:00

abstract：:A culture of peripheral nerve cells enriched in Schwann cells was obtained from sciatic nerve in normal and demyelinating trembler mutant. These cells incorporated and metabolized a non-physiological trans fatty acid (elaidic aid) as well as the physiological cis isomer (oleic acid). Both acids were incorporated simil...

journal_title：Neuroscience letters

authors： Bourre JM,Boutry JM,Masson M,Hauw JJ

更新日期：1982-05-28 00:00:00

abstract：:Dopamine-derived 1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines, (R)- and (S)salsolinol, released an enormous amount of serotonin in the rat striatum; the concentration of serotonin increased from undetectable level to 2.53 +/- 0.12 and 3.69 +/- 0.01 microM after perfusion of (R)- and (S)salsolinol, respective...

journal_title：Neuroscience letters

authors： Maruyama W,Nakahara D,Dostert P,Hashiguchi H,Ohta S,Hirobe M,Takahashi A,Nagatsu T,Naoi M

更新日期：1993-01-12 00:00:00

abstract：:Serotonin (5-HT) has been implicated in the regulation of circadian rhythms through its actions on the suprachiasmatic nucleus (SCN). Recent data suggests that, along with excitatory amino acids, serotonin may be important in the neural pathway that mediates the transmission of photic information to the circadian syst...

journal_title：Neuroscience letters

authors： Moyer RW,Kennaway DJ

更新日期：1999-08-27 00:00:00

abstract：:Aging is associated with cognitive deterioration. A recent study showed two polymorphisms (rs505058 in LMNA and rs11622883 near a SERPINA13 gene), identified in a genome-wide association study of late-onset Alzheimer's disease, to be associated with cognitive function (Mini Mental State Examination) in a UK elderly po...

journal_title：Neuroscience letters

authors： Yeh HL,Hou SJ,Yen FC,Hong CJ,Liou YJ,Yang AC,Liu ME,Tsai SJ

更新日期：2011-10-17 00:00:00

abstract：:Physiological and radioligand binding studies have demonstrated the existence of 5-HT3 receptors in the enteric nervous system. In order to determine if the cloned 5-HT3 receptor subunit, 5-HT3R-A, was expressed in the enteric nervous system of rats, we have performed in situ hybridization with 33P-labeled cRNA antise...

journal_title：Neuroscience letters

authors： Johnson DS,Heinemann SF

更新日期：1995-01-16 00:00:00

abstract：:Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels which mediate fast cholinergic synaptic transmission in insect and vertebrate nervous systems. A point mutation Y151S had been identified in Nilaparvata lugens (brown planthopper) that is associated with target-site resistance to neonicotinoid in...

journal_title：Neuroscience letters

authors： Zhang Y,Liu S,Gu J,Song F,Yao X,Liu Z

更新日期：2008-12-03 00:00:00

abstract：:We have recently documented the presence of cholinergic neurons containing monoamine oxidase (MAO)-B activity in the striatum of C57BL/6 mouse. In the present study, we have mapped the topographical distributions of MAO-containing neurons in the mouse striatum. Positive neurons were located in the striatum of the enti...

journal_title：Neuroscience letters

authors： Nakamura S,Akiguchi I,Kimura J

更新日期：1995-01-16 00:00:00

abstract：:The organotypic hippocampal slice culture technique was used to study how the effects of repeated ethanol withdrawal might differ between males and females at the cellular level, including potential modulation of subsequent insults. A chronic intermittent ethanol (CIE) exposure paradigm was employed, with 3 days of ex...

journal_title：Neuroscience letters

authors： Walls SA,Rosenwasser AM,Devaud LL

更新日期：2013-08-29 00:00:00

abstract：:One of the clinical characteristics of psychogenic tremors (PT) is the disruption or transient cessation of tremor with distractive manoeuvres, including those involving the performance of voluntary movements with the contralateral hand. Seven patients with PT, 11 patients with Parkinson's disease (PD), 10 patients wi...

journal_title：Neuroscience letters

authors： Kumru H,Valls-Solé J,Valldeoriola F,Marti MJ,Sanegre MT,Tolosa E

更新日期：2004-11-11 00:00:00

abstract：:Oligodendrocyte precursor cells (OPCs) play critical roles in maintaining the number of oligodendrocytes in white matter. Previously, we have shown that oxidative stress dampens oligodendrocyte regeneration after white matter damage, while a clinically proven radical scavenger, edaravone, supports oligodendrocyte repo...

journal_title：Neuroscience letters

authors： Takase H,Liang AC,Miyamoto N,Hamanaka G,Ohtomo R,Maki T,Pham LD,Lok J,Lo EH,Arai K

更新日期：2018-03-06 00:00:00

abstract：:The effects of noradrenaline (NA) on synaptic responses in layer II of the entorhinal cortex (EC) were studied in normal and spontaneously epileptic mutant mice tottering using intracellular recording in a slice preparation. Neither the membrane properties of neurones nor the responses to NA differed between normal an...

journal_title：Neuroscience letters

authors： Pralong E,Magistretti PJ

更新日期：1994-09-26 00:00:00

abstract：:Glutamate together with its N-methyl-d-aspartate (NMDA) receptors has an important role in the transmission of stimuli in the spinal cord. Whilst the expression of the various NMDA receptor subunits within the spinal cord has been investigated the subcellular location of the NMDA NR2B subunit has yet to be definitivel...

journal_title：Neuroscience letters

authors： O'Donnell R,Molon-Noblot S,Laroque P,Rigby M,Smith D

更新日期：2004-11-16 00:00:00

abstract：:IgGs from two LEMS patients applied to human neuroblastoma IMR32 cells reduced the density of low- (LVA; T) and high-threshold (HVA; L and N) Ba2+ currents by different percentages: 36% (LVA) and 56% (HVA) for one and 48% and 45% for the other. A pharmacological assay of IgGs action based on the block of L-type channe...

journal_title：Neuroscience letters

authors： Grassi C,Magnelli V,Carabelli V,Sher E,Carbone E

更新日期：1994-11-07 00:00:00