Effects of methamphetamine administration on brain neurotensin-like immunoreactivity in rats.

Abstract:

:The effects of methamphetamine (MAP) administration on neurotensin-like immunoreactivity (NTLI) were investigated in the rat brain. A single administration of MAP induced dose-dependent and reversible increases in NTLI in the caudate-putamen, limbic forebrain and midbrain. NTLI in the caudate-putamen, limbic forebrain and midbrain was also enhanced after repeated administration of MAP. It was assumed that MAP enhanced NTLI in the caudate-putamem, limbic forebrain and midbrain through its action upon the nigrostriatal and mesolimbic dopamine systems.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Wachi M,Okuda M,Togashi S,Miyashita O,Wakahoi T

doi

10.1016/0304-3940(87)90637-9

subject

Has Abstract

pub_date

1987-07-22 00:00:00

pages

222-6

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(87)90637-9

journal_volume

78

pub_type

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