Pre-pro-somatostatin mRNA in the developing rat spinal cord with special reference to ventral horn motoneurons.

abstract：:In the present study, an excitatory amino acid (EAA) pathway in the spinal cord which maintains sympathetic vasomotor tone in conscious rats has been investigated. To this end, the cardiovascular effects of an intrathecally administered EAA antagonist, kynurenate (KYN), were studied in conscious rats. KYN (0.5 mumol i...

journal_title：Neuroscience letters

authors： Verberne AJ,Widdop RE,Maccarrone C,Jarrott B,Beart PM,Louis WJ

更新日期：1990-07-13 00:00:00

abstract：:This study investigated the interaction between physical activity level and responses to transcutaneous spinal direct current stimulation (tsDCS) as reflected in changes in pressure pain threshold (PPT) in the lower extremity. Participants (n = 35, 15 males) consisted of physically active young adults. PPTs were deter...

journal_title：Neuroscience letters

authors： Gibson J,Tremblay F

更新日期：2019-04-17 00:00:00

abstract：:The anatomical distribution of insulin-degrading enzyme (IDE) was studied in normal and Alzheimer's disease (AD) human brains. By use of a monospecific, polyclonal antiserum against the enzyme we identified IDE antigen in multiple cortical and subcortical neurons. Glia did not show IDE immunoreactivity. In AD brains i...

journal_title：Neuroscience letters

authors： Bernstein HG,Ansorge S,Riederer P,Reiser M,Frölich L,Bogerts B

更新日期：1999-03-26 00:00:00

abstract：:Tripeptidyl peptidase-I (TPP-I) is a lysosomal exopeptidase which removes tripeptides from the N-terminus of small proteins. Mutations in the TPP-I gene result in a lethal neurodegenerative disease, late infantile neuronal ceroid lipofuscinosis. The pathological consequences of loss of activity are only manifested in ...

journal_title：Neuroscience letters

authors： Warburton MJ,Bernardini F

更新日期：2002-10-11 00:00:00

abstract：:Vlgr1 (very large G-protein coupled receptor 1) knockout mice against hybrid backgrounds of the 129/Ola and C57BL/6 mouse strains show hearing deficit and high susceptibility to audiogenic seizures. The present study examined how hearing impairment and susceptibility to audiogenic seizures in Vlgr1-deficient mice chan...

journal_title：Neuroscience letters

authors： Yagi H,Noguchi Y,Kitamura K,Sato M

更新日期：2009-09-18 00:00:00

abstract：:Dominance hierarchies within social groups determine resource distribution. Resources, such as food and access to mating partners, can act as reinforcers. The present study examined the effect of social rank on access to wheel running-a reinforcing behavior performed by laboratory animals. Mice were identified as domi...

journal_title：Neuroscience letters

authors： Vargas-Pérez H,Sellings L,Grieder T,Díaz JL

更新日期：2009-07-03 00:00:00

abstract：:We combined fluorescent tracing with immunohistochemistry to examine nitric oxide synthase (NOS) containing neurons in the rat ventral lateral geniculate nucleus (vLGN). NOS immunopositive neurons in vLGN had a similar appearance to previously described NADPH-d positive neurons. The majority (96%) of the NOS immunopos...

journal_title：Neuroscience letters

authors： Meng XW,Ohara PT,Ralston HJ 3rd

更新日期：1998-11-06 00:00:00

abstract：:The monoamine innervation of the organum vasculosum lamina terminalis (OVLT) was studied using fluorescence histochemistry and the autoradiographic tracing method. Fluorescence histochemistry demonstrates serotonin terminals in close proximity to the capillary plexus of the OVLT, in the same region where the apparent ...

journal_title：Neuroscience letters

authors： Moore RY

更新日期：1977-08-01 00:00:00

abstract：:The effects of methysergide (1 mg, p.o.), clonidine (50 micrograms, i.m.) and methysergide plus clonidine on growth hormone (GH) and prolactin (PRL) secretion in 8 normal male volunteers have been studied. Both methysergide and clonidine were found to enhance GH and to lower PRL plasma levels. The effects of methyserg...

journal_title：Neuroscience letters

authors： Agnati LF,Benfenati F,Capelli M,Cocchi V,D'Errico A,Bernardi P

更新日期：1981-02-06 00:00:00

abstract：:Experiments were conducted to examine whether renal sympathetic nerve activity (RSNA) and water intake in response to central salt-loading or angiotensin II (A II) differ between freely-moving Dahl salt-sensitive (DS) and -resistant (DR) rats maintained on a low-salt diet. Intracerebroventricular (i.c.v.) administrati...

journal_title：Neuroscience letters

authors： Kato K,Saita M,Ishizuka Y,Nose K,Kunitake T,Hanamori T,Kannan H

更新日期：1998-02-06 00:00:00

abstract：:Electrical stimulation of the primary auditory cortex (AI) of the cat was found to evoke EPSPs, IPSPs or EPSP-IPSP sequences in colliculogeniculate (CG) neurons in the inferior colliculus (IC) which responded antidromically to stimulation of the medial geniculate nucleus. The CG neurons responding to the AI stimulatio...

journal_title：Neuroscience letters

authors： Mitani A,Shimokouchi M,Nomura S

更新日期：1983-12-02 00:00:00

abstract：:The content of the neurosteroids, dehydroepiandrosterone (DHEA) in the brain decreases with aging. Also the oxidative energy metabolism is known to decrease with aging. Hence we examined the effects of treatment with DHEA (0.2 or 1.0 mg/kg body weight for 7 days) on oxidative energy metabolism in brain mitochondria fr...

journal_title：Neuroscience letters

authors： Patel MA,Katyare SS

更新日期：2006-07-10 00:00:00

abstract：:Event-related brain potentials (ERPs) demonstrate that human auditory cortical responses are sensitive to changes in static pitch as indexed by the pitch onset response (POR), a negativity generated at the initiation of acoustic periodicity. Yet, it is still unclear if this brain signature is sensitive to dynamic, tim...

journal_title：Neuroscience letters

authors： Bidelman GM

更新日期：2015-08-31 00:00:00

abstract：:Morphine blocked decremental bar pressing of rats to escape electrical stimulation of aversive midbrain sites. These sites included the dorsal central gray area (DCG), the ventral reticular formation (VRF) and the lateral tegmentum (LT). Naloxone, which had no effect alone, blocked the morphine effects of all three av...

journal_title：Neuroscience letters

authors： Kiser RS,German DC

更新日期：1978-11-01 00:00:00

abstract：:We determined the effect of naloxone and morphine on the differentiation of pheochromocytoma cell, the PC12 cells, induced by nerve growth factor (NGF). PC12 cells were grown in medium containing NGF with or without the addition of naloxone or morphine for up to 10-day treatments. NGF-induced morphological differentia...

journal_title：Neuroscience letters

authors： Yeh GC,Hsieh TH,Chang SF

更新日期：1998-08-07 00:00:00

abstract：:Amphiphilic monomers and dimers of acetylcholinesterase (AChE) and hydrophilic tetramers of butyrylcholinesterase (BuChE) were released by extracting human meningioma with Tris-saline and Tris-saline-Triton X-100 buffers. The amphiphilic or hydrophilic behavior of the AChE and BuChE forms was assessed by sedimentation...

journal_title：Neuroscience letters

authors： Sáez-Valero J,Vidal CJ

更新日期：1995-08-04 00:00:00

abstract：OBJECTIVES:Suicide attempt in schizophrenia is an important clinical issue. We performed a genome-wide association study to identify genetic markers, which increase the risk for suicide attempt in schizophrenia. METHODS:Suicide attempt lifetime was assessed in 121 schizophrenia patients and defined by the means of the...

journal_title：Neuroscience letters

authors： Bani-Fatemi A,Graff A,Zai C,Strauss J,De Luca V

更新日期：2016-05-27 00:00:00

abstract：:Nitric oxide (NO) mediates cell-cell signalling in the brain and stimulates cyclic GMP (cGMP) production in target cells. We have used NADPH-diaphorase (reduced nicotinamide adenine dinucleotide phosphate-diaphorase) histochemistry to identify NO-producing neurones and cGMP immunohistochemistry to locate the targets o...

journal_title：Neuroscience letters

authors： Southam E,Morris R,Garthwaite J

更新日期：1992-03-30 00:00:00

abstract：:Alzheimer's disease (AD) is a complex disease with the possible involvement of several genes. Genetic studies on sporadic late-onset AD have determined APOE*4 to be the major risk factor. Members of the synuclein gene family are potential candidates for the risk of AD. The persyn gene (gamma-synuclein) has recently be...

journal_title：Neuroscience letters

authors： Luedecking EK,Ganguli M,DeKosky ST,Kamboh MI

更新日期：1999-02-19 00:00:00

abstract：:Carbonic anhydrase (CA) activity was localized histochemically in the retina and brain of the honeybee drone. A positive reaction that could be inhibited with 10(-5) M acetazolamide was found only in brain glial cells such as those in the lamina and medulla of the optic lobes. In the retina, neither the photoreceptors...

journal_title：Neuroscience letters

authors： Walz B

更新日期：1988-02-15 00:00:00

abstract：:Horseradish peroxidase (HRP) was injected into the thalamic ventral tier of squirrel monkey and the brainstem was examined for the presence of HRP-reactive cells in the external cuneate nucleus (ECN), nuclei Z and X, and the mesencephalic nucleus of the trigeminal nerve (MNV). Results indicate that the ECN, Z and X ha...

journal_title：Neuroscience letters

authors： Pearson JC,Garfunkel DA

更新日期：1983-10-31 00:00:00

abstract：:The endogenously synthesized nonapeptide arginine vasopressin (AVP) is thought to be involved in transduction of photic information to the pineal gland. The enhancement of circulating AVP leads to a suppression of the nocturnal melatonin surge the mechanisms of which are unknown so far. We therefore studied the effect...

journal_title：Neuroscience letters

authors： Stehle J,Reuss S,Riemann R,Seidel A,Vollrath L

更新日期：1991-02-11 00:00:00

abstract：:Activation of several immediate early genes (IEGs) is crucial for long-term memory formation in vivo. In vitro methods of inducing these genes have not been investigated extensively. Here we present data demonstrating that application of the neurotrophin, nerve growth factor (NGF), to both rat primary neuronal culture...

journal_title：Neuroscience letters

authors： Dickey CA,De Mesquita DD,Morgan D,Pennypacker KR

更新日期：2004-08-05 00:00:00

abstract：:A FORTRAN computer program is described which enables solution of a set of partial differential equations describing synaptic transmission, including neurotransmitter diffusion, binding to receptors on the postsynaptic membrane with subsequent formation of open ion-conducting channels, and hydrolysis. Integration is p...

journal_title：Neuroscience letters

authors： Madsen BW,Edeson RO,Lam HS,Milne RK

更新日期：1984-07-13 00:00:00

abstract：:Accumulating evidence indicates that obesity is an independent risk factor for developing Alzheimer disease (AD). Recent studies have shown that diet-induced obesity (DIO) enhances AD-related pathologies in transgenic mouse models of the disease. DIO increases amyloid β (Aβ) deposition in amyloidogenic transgenic mice...

journal_title：Neuroscience letters

authors： Koga S,Kojima A,Kuwabara S,Yoshiyama Y

更新日期：2014-06-13 00:00:00

abstract：:A procedure for dissociating viable taste cells from the rodent tongue was described. After the tongue was excised, the foliate and circumvallate papillae from the posterior region were blocked to small pieces and incubated for 2-3 h in a calcium-free salt solution containing the enzyme papain. The pieces were then tr...

journal_title：Neuroscience letters

authors： Herness MS

更新日期：1989-11-20 00:00:00

abstract：:Following various types of wounds and subsequent denervation, the reinnervation of the rabbit corneal epithelium was found to occur in two distinct phases that overlapped in time. In the first phase large numbers of collateral sprouts originated from the unmyelinated plexus at various distances proximal to the site of...

journal_title：Neuroscience letters

authors： Beuerman RW,Rózsa AJ

更新日期：1984-01-27 00:00:00

abstract：:In decerebrate cats, intracellular recordings were made in 124 expiratory neurons displaying either a plateau-phase of depolarization during post-inspiration or a steadily decrementing depolarization throughout expiration. Both groups consisted of vagal motoneurons and non-antidromically activated neurons. Five neuron...

journal_title：Neuroscience letters

authors： Haji A,Takeda R

更新日期：1993-01-12 00:00:00

abstract：:Neural circuitry comprising the ventral tegmental area, nucleus accumbens (NAc), prefrontal cortex (PFC) and hippocampus (HIP) has a main role in reward phenomena. Previous behavioral studies indicated that intracerebroventricular administration of AP5 (NMDA glutamate receptor antagonist) and CNQX (AMPA/kainate glutam...

journal_title：Neuroscience letters

authors： Siahposht-Khachaki A,Ezzatpanah S,Razavi Y,Haghparast A

更新日期：2018-01-01 00:00:00

abstract：:Hippocampal output is mediated via the subiculum, which is the principal target of CA1 pyramidal cells, and which sends projections to a variety of cortical and subcortical regions. Pyramidal cells in the subiculum display two different firing modes and are classified as being burst-spiking or regular-spiking. In a pr...

journal_title：Neuroscience letters

authors： Shor OL,Fidzinski P,Behr J

更新日期：2009-01-16 00:00:00