Loss of alpha power is related to increased gamma synchronization-A marker of reduced inhibition in tinnitus?

Abstract:

:Tinnitus is the perception of sound in the absence of any external auditory stimulus. Based on previous research we have proposed a framework which postulates that the reduction of ongoing inhibitory alpha activity in tinnitus subjects favors a synchronization of neurons in the gamma frequency range while in a resting state. In the present work we are validating the existence of an inverse relationship between auditory gamma and alpha activity in tinnitus and control subjects using Magnetoencephalography. Tinnitus subjects exhibited a significantly steeper slope of the regression line compared to controls, presumably because a greater number of subjects concurrently exhibited low alpha and high gamma power. Therefore, the role of the alpha-gamma pattern is discussed regarding its possible implication for the generation of tinnitus.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Lorenz I,Müller N,Schlee W,Hartmann T,Weisz N

doi

10.1016/j.neulet.2009.02.028

subject

Has Abstract

pub_date

2009-04-10 00:00:00

pages

225-8

issue

3

eissn

0304-3940

issn

1872-7972

pii

S0304-3940(09)00212-2

journal_volume

453

pub_type

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