Serotoninergic endings on VIP-neurons in the suprachiasmatic nucleus and on ACTH-neurons in the arcuate nucleus of the rat hypothalamus. A combination of high resolution autoradiography and electron microscopic immunocytochemistry.

Abstract:

:A combination of immunocytochemistry with transmitter specific autoradiography at the electron microscopic level was used to identify vasoactive intestinal polypeptide (VIP)- or ACTH-containing neurons and serotoninergic nerve terminals in the suprachiasmatic (SCN) and arcuate nuclei (AN). We observed nerve terminals showing selective uptake of [3H]serotonin forming synaptic contact with perikarya or dendrites where the postsynaptic structures exhibited VIP-like immunoreactivity in the SCN and ACTH-like immunoreactivity in the AN. The findings provide ultrastructural evidence that serotoninergic nerve fibers terminate on VIP-neurons in the SCN and on ACTH-neurons in the AN.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Kiss J,Léránth C,Halász B

doi

10.1016/0304-3940(84)90068-5

subject

Has Abstract

pub_date

1984-02-10 00:00:00

pages

119-24

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(84)90068-5

journal_volume

44

pub_type

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