Abstract:
:Double immunostaining for oxytocin (OT) and Fos was used to study the oxytocinergic system of the rat hypothalamic paraventricular nucleus (PVN) following intraperitoneal insulin injections. The expression of c-fos in the PVN appeared about 3 h after insulin treatment and was very high after 5 h while no labelling was observed in isotonic saline-injected animals. Twelve to 18% of OT neurons expressed Fos-like immunoreactivity and these activated neurons were found in both the magno- and the parvocellular compartments of the PVN suggesting that the OT neuron responses to insulin induced disturbances are complex and involve hormonal as well as autonomic pathways.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Griffond B,Deray A,Bahjaoui-Bouhaddi M,Colard C,Bugnon C,Fellmann Ddoi
10.1016/0304-3940(94)90304-2subject
Has Abstractpub_date
1994-08-29 00:00:00pages
119-23issue
1eissn
0304-3940issn
1872-7972pii
0304-3940(94)90304-2journal_volume
178pub_type
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