Reduced and oxidized glutathione in human and monkey brain.

abstract：:Using a combination of intracellular recording and morphological techniques, we describe the properties of a new cell type within layer II of the lateral entorhinal cortex. A thick and bifurcating apical dendrite and thinner basal dendrites extended from the pyramidal shaped cell body. The axon ramified within all sup...

journal_title：Neuroscience letters

authors： Empson RM,Gloveli T,Schmitz D,Heinemann U

更新日期：1995-07-07 00:00:00

abstract：:Three dopamine receptor mRNAs were detected by reverse polymerase chain reaction in the rat forebrain during ontogeny. The D1 receptor mRNA gave a faint signal from gestational day 11 (G11) on, while the D1b receptor was not detectable before G12. The D3 receptor mRNA was slightly expressed at G11 and clearly present ...

journal_title：Neuroscience letters

authors： Cadoret MA,Jaber M,Bloch B

更新日期：1993-05-28 00:00:00

abstract：:6-day-old mice pups were injected with D-amino acids (D-phenyl-alanine + D-leucine), and their ultrasonic distress vocalizations were measured. D-Amino acids, which exert opioid-like effects, reduce the number of ultrasonic calls without affecting the activity of the pups. This effect is reversed by naloxone, an opioi...

journal_title：Neuroscience letters

authors： Albonetti ME,D'Udine B,Oliverio A

更新日期：1985-06-24 00:00:00

abstract：:In urethane-chloralose anesthetized rats, the role of GABA(B) receptor in the commissural subnucleus of the nucleus tractus solitarii (commNTS) on the carotid chemoreceptor reflex was investigated. Microinjection of a GABA(B) agonist baclofen into the commNTS did not have any effects on arterial blood pressure (BP) or...

journal_title：Neuroscience letters

authors： Suzuki M,Tetsuka M,Endo M

更新日期：1999-01-22 00:00:00

abstract：:The known regional abnormality of the dorsolateral prefrontal cortex (DLPFC) and its role in various neural circuits in schizophrenia has given prominence to its importance in studies on the dysconnection associated with schizophrenia. Abnormal functional connectivities of the DLPFC have been found during various goal...

journal_title：Neuroscience letters

authors： Zhou Y,Liang M,Jiang T,Tian L,Liu Y,Liu Z,Liu H,Kuang F

更新日期：2007-05-07 00:00:00

abstract：:Intracellular recordings were used to examine the mechanisms underlying the 5-hydroxytryptamine (5-HT)4 receptor-mediated depolarization seen in CA1 region pyramidal cells in in vitro hippocampal brain slices. This depolarization was mimicked and occluded by administration of the membrane permeable cyclic adenosine mo...

journal_title：Neuroscience letters

authors： Chapin EM,Haj-Dahmane S,Torres G,Andrade R

更新日期：2002-05-10 00:00:00

abstract：:Several studies on the relationship between event-related desynchronization/synchronization (ERD/ERS) and cognitive performance revealed contradictory results particularly for the alpha band. Studies from our laboratory have shown that good performers show a larger upper alpha ERD (interpreted in terms of larger corti...

journal_title：Neuroscience letters

authors： Doppelmayr M,Klimesch W,Sauseng P,Hödlmoser K,Stadler W,Hanslmayr S

更新日期：2005-06-24 00:00:00

abstract：:A two-tone oddball procedure was employed to examine the effect of a phonemic category on the mismatch negativity (MMN). One of the stimuli was a phoneme prototype of Japanese /e/, and the other, [e/ö], which was perceived by Japanese participants as showing deviance from typicality but is nonetheless included in the ...

journal_title：Neuroscience letters

authors： Ikeda K,Hayashi A,Hashimoto S,Otomo K,Kanno A

更新日期：2002-03-22 00:00:00

abstract：:Alternative cleavage of the amyloid precursor protein (APP) results in generation and secretion of both soluble APP (sAPP) and beta-amyloid (Abeta). Abeta is the main component of the amyloid depositions in the brains of Alzheimer's disease (AD) patients. Using Western blotting, we compared the levels of alpha-secreta...

journal_title：Neuroscience letters

authors： Sennvik K,Fastbom J,Blomberg M,Wahlund LO,Winblad B,Benedikz E

更新日期：2000-01-14 00:00:00

abstract：:The sexual differences and the seasonal variation in the vasoactive intestinal peptide (VIP) content of the suprachiasmatic nucleus (SCN) of a desert rodent, the jerboa (Jaculus orientalis) were studied using immunocytochemical techniques. During the period of sexual activity (spring-early summer), the VIP immunoreact...

journal_title：Neuroscience letters

authors： Lakhdar-Ghazal N,Kalsbeek A,Pevet P

更新日期：1992-09-14 00:00:00

abstract：:Current theories of orbitofrontal cortex (OFC) function suggest that this region should participate in the generation of error-related signals associated with the outcomes of actions. We investigated the impact of lesions to OFC on the error-related negativity (ERN), an electrophysiological marker of performance monit...

journal_title：Neuroscience letters

authors： Turken AU,Swick D

更新日期：2008-08-15 00:00:00

abstract：:Turnover rates, as estimated from the accumulation of the intermediates, 3,4-dihydroxyphenylalanine (DOPA) and 5-hydroxytryptophan (5-HTP) following decarboxylase inhibition, were used to investigate the relationship between central catecholaminergic and serotonergic neurons and the development of hypertension in the ...

journal_title：Neuroscience letters

authors： Shum AY,Chen CS,Hsu SC,Chen CF

更新日期：1987-03-31 00:00:00

abstract：:Compromised oxygen supply to cerebral tissue could be an important mechanism contributing to age-related cognition decline. We recently showed in awake mice that resting cerebral tissue pO2 decreases with age, a phenomenon that manifests mainly after middle-age. To extend these findings, here we aimed to study how tis...

journal_title：Neuroscience letters

authors： Moeini M,Lu X,Bélanger S,Picard F,Boas D,Kakkar A,Lesage F

更新日期：2019-04-23 00:00:00

abstract：:Noise-induced hearing loss (NIHL) severely impacts the quality of life of affected individuals. Oxidative stress resulting from noise exposure is a significant cause of NIHL. Although histone deacetylase (HDAC) inhibitors were shown to protect against NIHL, the underlying mechanism remains unclear, and it is not known...

journal_title：Neuroscience letters

authors： Yang DH,Xie J,Liu K,Peng Z,Guo JY,Yu SK,Wang GP,Gong SS

更新日期：2017-11-01 00:00:00

abstract：:To examine whether the Haken-Kelso-Bunz model for rhythmic interlimb coordination applies to walking side-by-side on a treadmill, we invited six pairs of participants to coordinate their stepping movements at seven prescribed relative phases (between 0 degrees and 180 degrees ) to scan the attractor layout governing t...

journal_title：Neuroscience letters

authors： van Ulzen NR,Lamoth CJ,Daffertshofer A,Semin GR,Beek PJ

更新日期：2010-04-26 00:00:00

abstract：:2-Deoxy-d-glucose (2DG) is an analog of glucose that is effectively taken up by cells competing with normal glucose but cannot be further utilized to produce energy. It was previously reported that 2DG can mimic the beneficial effects of dietary restriction in experimental models of neurodegenerative disorders and can...

journal_title：Neuroscience letters

authors： Park M,Song KS,Kim HK,Park YJ,Kim HS,Bae MI,Lee J

更新日期：2009-01-16 00:00:00

abstract：:Cdk5 (cyclin-dependent kinase 5) is a serine/threonine kinase implicated to play pivotal roles in neuronal development. Recently, its potential involvement as a regulator of neuronal death and survival has attracted considerable interests. Importantly, increasing evidence has linked Cdk5 to the etiopathology of neurod...

journal_title：Neuroscience letters

authors： Cheung ZH,Ip NY

更新日期：2004-05-06 00:00:00

abstract：:By the use of light microscopic immunohistochemistry it was shown that a significant population of small primary sensory afferents of guinea pig contains immunoreactivities to antisera directed against prodynorphin-opioid peptides, whereas immunoreactivities to antisera directed against opioid peptides exclusively con...

journal_title：Neuroscience letters

authors： Weihe E,Hartschuh W,Weber E

更新日期：1985-08-05 00:00:00

abstract：:The commonly used benzidine derivatives such as diaminobenzidine, o-dianisidine and benzidine dihydrochloride are apparently carcinogenic. Available information, however, indicates that tetramethyl benzidine (TMB) is safer in this regard, and we have therefore developed a procedure in which TMB is used as a substrate ...

journal_title：Neuroscience letters

authors： Hardy H,Heimer L

更新日期：1977-08-01 00:00:00

abstract：:Localized moderate cooling (+10 degrees C) of the anterior and ventral part of the raphe dorsalis induced cortical synchronization and ponto-geniculo-occipital (PGO) waves followed sometimes by paradoxical sleep. Cooling the region of the raphe magnus produced cortical arousal. After depletion of brain 5-hydroxytrypta...

journal_title：Neuroscience letters

authors： Cespuglio R,Walker E,Gomez ME,Musolino R

更新日期：1976-11-01 00:00:00

abstract：:The phenotypic manifestation of McArdle disease varies considerably from one individual to the next. The purpose of this study was to assess the possible association between the clinical severity of the disease, and each of the genotypes PYGM (R50X), ACE (I/D), AMPD1 (Q12X), PPARGC1A (G482S) and ACTN3 (R577X). We also...

journal_title：Neuroscience letters

authors： Rubio JC,Gómez-Gallego F,Santiago C,García-Consuegra I,Pérez M,Barriopedro MI,Andreu AL,Martín MA,Arenas J,Lucia A

更新日期：2007-07-18 00:00:00

abstract：:Recent findings indicated that the excitotoxicity of glutamate analogues was prevented in the mammalian nervous system by N-methyl-D-aspartate (NMDA) antagonists. The neurodegenerative effects of kainic acid, and the putative protection of MK-801 and 6,7-dinitroquinoxaline-2,3-dione (DNQX), were investigated by morpho...

journal_title：Neuroscience letters

authors： Villani L,Carraro S,Guarnieri T

更新日期：1995-06-09 00:00:00

abstract：:The processing of sound information is mediated by the cochlea and the central auditory system. Among the central auditory system, the inferior colliculus (IC) has leading roles in the acoustic processing. In a previous study, we demonstrated psychiatric disorder-related behavioral abnormalities in a genetically modif...

journal_title：Neuroscience letters

authors： Nakajima M,Nishikawa C,Miyasaka Y,Kikkawa Y,Mori H,Tsuruta M,Okuyama S,Furukawa Y

更新日期：2014-04-30 00:00:00

abstract：:The prioritized processing of threat is suggested to be motivated by anxiety, regulated by the parasympatheticus, and biased to the right hemisphere. However, according to an anterior dimensional model of negative affect this is unlikely to be true when threat is of social origin. Social threat is communicated by the ...

journal_title：Neuroscience letters

authors： van Honk J,Hermans EJ,d'Alfonso AA,Schutter DJ,van Doornen L,de Haan EH

更新日期：2002-02-15 00:00:00

abstract：:To clarify the details of the involvement of Ca(2+)-calmodulin in gating of C1-channels, effects of a novel calmodulin-dependent protein kinase II (CaMK II) inhibitor, KN-62, on C1-current and C1-efflux induced by serotonin (5-HT) were investigated in Xenopus oocyte injected with rat brain mRNA. 5-HT evoked inward cur...

journal_title：Neuroscience letters

authors： Tohda M,Nakamura J,Hidaka H,Nomura Y

更新日期：1991-08-05 00:00:00

abstract：:Following virus infection of the central nervous system, microglia become activated and undergo morphological as well as functional transformations, thereby initiating effective antiviral actions. Herein, we have examined the contribution of nuclear factor kappaB (NF-kappaB) and mitogen-activated protein kinase (MAPK)...

journal_title：Neuroscience letters

authors： Nakamichi K,Saiki M,Kitani H,Kuboyama Y,Morimoto K,Takayama-Ito M,Kurane I

更新日期：2007-03-13 00:00:00

abstract：:The effects of tetrahydro-9-aminoacridine (THA) on beta-adrenoceptor activation-induced synaptic potentiation were studied in brain slices of the rat amygdala using intracellular recording techniques. To exclude the involvement of N-methyl-D-aspartate (NMDA) receptors, all the experiments were performed in the presenc...

journal_title：Neuroscience letters

authors： Wang SJ,Huang CC,Hsu KS,Tsai JJ,Huang CC,Gean PW

更新日期：1996-08-23 00:00:00

abstract：:Event-related potentials were recorded from sleeping newborns to compare amplitudes and latencies of mismatch negativity (MMN) and late discriminative negativity (LDN) in active and quiet sleep stages. MMN and LDN were obtained in response to changes in semi-synthesized vowels from 20 healthy newborn infants. MMN and ...

journal_title：Neuroscience letters

authors： Martynova O,Kirjavainen J,Cheour M

更新日期：2003-04-10 00:00:00

abstract：:Isolated Helix neurons were internally perfused under voltage-clamp, with drugs applied by the 'concentration clamp' which allowed an extremely rapid switching of the external solution. 4-Aminopyridine (4-AP) at more than 3 X 10(-4) M induced a chloride current (ICl) which could be blocked by D-tubocurarine. Acetylcho...

journal_title：Neuroscience letters

authors： Ikemoto Y,Akaike N,Ono K

更新日期：1987-04-23 00:00:00

abstract：:The strength of feedforward inhibition was assessed in the CA1 region of in vitro hippocampus of benzodiazepine tolerant rats 2 and 7 days after 1 week oral flurazepam (FZP) administration. Feedforward inhibition was activated with a Schaffer collateral stimulation just-subthreshold for a population spike followed at ...

journal_title：Neuroscience letters

authors： Zeng X,Xie XH,Tietz EI

更新日期：1994-05-23 00:00:00