Blockade of isoproterenol-induced synaptic potentiation by tetra-9-aminoacridine in the rat amygdala.

abstract：:The retina and nucleus isthmi both project in laminar fashion to the superficial layers of the frog's tectum. In order to determine whether isthmo-tectal axons show collateral sprouting after retinotectal input is removed, we injected [3H] proline into the nucleus isthmi and measured the volume of the crossed isthmo-t...

journal_title：Neuroscience letters

authors： Udin SB,Gruberg ER

更新日期：1981-12-11 00:00:00

abstract：:Brain pH is thought to be an influential factor in determining susceptibility to seizures. We compared the susceptibility of brain slices from carbonic anhydrase II (CA II)-deficient mice to epileptiform activity induced by low extracellular [Mg2+], with slices from normal littermates, both bathed in artificial cerebr...

journal_title：Neuroscience letters

authors： Velísek L,Moshé SL,Stanton PK

更新日期：1996-04-05 00:00:00

abstract：:Neocortical neurofibrillary tangles (NFT) revealed by Bodian technique and anti-tau immunolabelling were seen in 5/5 cases of progressive supranuclear palsy (PSP) aged 58-76 years. These lesions differed from Alzheimer's disease or age-related changes: (1) they were most frequent in the precentral gyrus (Brodmann's ar...

journal_title：Neuroscience letters

authors： Hauw JJ,Verny M,Delaère P,Cervera P,He Y,Duyckaerts C

更新日期：1990-11-13 00:00:00

abstract：:Retinofugal projections in the house musk shrew (Suncus murinus) were studied with the WGA-HRP method. After WGA-HRP injection into the vitreous cavity of one eye, terminal labeling was seen in the suprachiasmatic nucleus, dorsal and ventral lateral geniculate nuclei, pretectum and superficial layer of the superior co...

journal_title：Neuroscience letters

authors： Mizuno N,Sumi MU,Tashiro T,Takahashi O,Satoda T

更新日期：1991-04-29 00:00:00

abstract：:The restoration of motor function is important in daily life in patients with brain damage. Although attentional concentration can affect motor function, most physical therapists focus only on therapeutic exercise. Therefore, we investigated changes in motor function in patients with high attentional concentration dur...

journal_title：Neuroscience letters

authors： Ha SY,Sung YH

更新日期：2020-09-25 00:00:00

abstract：:APPsw transgenic mice showing substantial features of brain Abeta amyloidosis such as senile plaques and behavioral abnormalities were examined by immunostaining to determine whether Abeta deposits could induce the subsequent disturbance of neurotransmitter systems including somatostatin, substance P and choline acety...

journal_title：Neuroscience letters

authors： Tomidokoro Y,Harigaya Y,Matsubara E,Ikeda M,Kawarabayashi T,Okamoto K,Shoji M

更新日期：2000-10-13 00:00:00

abstract：:Cationic liposomes are commonly used to introduce foreign genes to the target cells. However, the methods are not applicable to several types of cells such as neuronal cells. We introduced the luciferase gene to the neuronal pheochromocytoma-12 (PC12) cells by cationic liposomes with a cationic cholesterol derivative ...

journal_title：Neuroscience letters

authors： Noguchi A,Hirashima N,Furuno T,Nakanishi M

更新日期：2002-05-31 00:00:00

abstract：:The efficiency of antisense approaches to produce a selective regional inhibition of the expression of brain 5-HT1A receptors was tested in the rat. In vivo ICV injections of modified antisense oligodesoxynucleotides yielded at most an 18% specific decrease in 5-HT1A receptor expression in the hippocampus only, as mea...

journal_title：Neuroscience letters

authors： Sari Y,Sibella C,Vergé D,Hamon M,Miquel MC

更新日期：1999-01-15 00:00:00

abstract：:Mutations in the hairless (hr) gene of mice result in hair follicle and other epithelial defects. The hr gene is expressed at high levels in the brain where it probably participates in the survival and maintenance of some neuronal populations, but whether it also supports glial populations of the central nervous syste...

journal_title：Neuroscience letters

authors： San Jose I,García-Atares N,Pelaez B,Cabo R,Esteban I,Vega JA,Represa J

更新日期：2001-08-24 00:00:00

abstract：:Against the current concept of abortive regeneration of axotomized neurons in the mammalian central nervous system, the occurrence of remarkable axonal regeneration of cerebellothalamic projection neurons following transection of the decussation of the superior cerebellar peduncle was proved in kittens morphologically...

journal_title：Neuroscience letters

authors： Kawaguchi S,Miyata H,Kawamura M,Harada Y

更新日期：1981-08-07 00:00:00

abstract：:Hippocampal output is mediated via the subiculum, which is the principal target of CA1 pyramidal cells, and which sends projections to a variety of cortical and subcortical regions. Pyramidal cells in the subiculum display two different firing modes and are classified as being burst-spiking or regular-spiking. In a pr...

journal_title：Neuroscience letters

authors： Shor OL,Fidzinski P,Behr J

更新日期：2009-01-16 00:00:00

abstract：:NMDA and non-NMDA receptor-mediated components of excitatory post-synaptic current (EPSC) were studied by in situ whole-cell voltage-clamp recordings in the CA1 field of rat hippocampus. We found that the amplitudes ratio of the NMDA to the non-NMDA components can be strongly increased by blocking A1 adenosine recepto...

journal_title：Neuroscience letters

authors： Klishin A,Lozovaya N,Krishtal O

更新日期：1994-09-26 00:00:00

abstract：:Projection of the vagal C-afferent to the insular cortex was examined in rats. Electrical activation of the C-afferent resulted in two cortical field potentials in the anterior insula. They were independent of each other and neither of them was attributed to the specific thalamic projection. These results imply that v...

journal_title：Neuroscience letters

authors： Ito S

更新日期：1992-12-14 00:00:00

abstract：:NMDA receptors play important roles in brain formation by taking part in synaptogenesis and apoptosis. In the present study, the expression of NMDA receptors was analyzed in a neural stem cell line, MSP-1, which lacks p53. p53 is a transcription factor involved in excitotoxic neuronal apoptosis. It is quite likely tha...

journal_title：Neuroscience letters

authors： Yamada K,Hisatsune T,Uchino S,Nakamura T,Kudo Y,Kaminogawa S

更新日期：1999-04-02 00:00:00

abstract：:To evaluate the roles of complement in kainic acid (KA)-induced neuronal damages, the immunohistochemical localization of the complement protein C3 was examined in rat hippocampus after systemic KA injection. The immunoreactivity for C3 was found in glial cells in control rats, and such glial cells were increased in n...

journal_title：Neuroscience letters

authors： Morita H,Suzuki K,Mori N,Yasuhara O

更新日期：2006-11-27 00:00:00

abstract：:Methamphetamine (METH) is a well-known drug of abuse and neurotoxin that may cause temporary or permanent disturbances in the dopaminergic systems of the brain, predisposing individuals to Parkinsonism. Previously, we have shown that METH causes dopaminergic cell death by increasing the production of reactive oxygen s...

journal_title：Neuroscience letters

authors： Ajjimaporn A,Phansuwan-Pujito P,Ebadi M,Govitrapong P

更新日期：2007-05-23 00:00:00

abstract：BACKGROUND:Studies have demonstrated that the failure of oligodendrocyte precursor cells (OPCs) differentiation as a major cause of remyelination failure in demyelinating disease. The reasons for this failure are not completely understood. We hypothesized that the present of myelin debris in CNS play an important role ...

journal_title：Neuroscience letters

authors： Liu Q,Lv HW,Yang S,He YQ,Ma QR,Liu J

更新日期：2020-04-23 00:00:00

abstract：:Cancer patients with bone metastases often suffer breakthrough pain. However, little progress has been made in the treatment of breakthrough pain and its associated mechanism(s) in the patient with cancer due to lacking of resembling and predictive animal models. We previously have demonstrated that endothelin-1 plays...

journal_title：Neuroscience letters

authors： Tang Y,Peng H,Liao Q,Gan L,Zhang R,Huang L,Ding Z,Yang H,Yan X,Gu Y,Zang X,Huang D,Cao S

更新日期：2016-03-23 00:00:00

abstract：:The effects of histamine (HA) on the resting membrane potential and input resistance of rat medial vestibular nucleus (MVN) neurons were investigated using intracellular recording techniques from a submerged brain slice preparation. The exogenous application of HA predominantly produced a concentration-dependent membr...

journal_title：Neuroscience letters

authors： Phelan KD,Nakamura J,Gallagher JP

更新日期：1990-02-16 00:00:00

abstract：:Vesicular acetylcholine transporter (VAChT) function is essential for organismal survival, mediating the packaging of acetylcholine (ACh) for exocytotic release. However, its expression pattern in the Drosophila brain has not been fully elucidated. To investigate the localization of VAChT, we developed an antibody aga...

journal_title：Neuroscience letters

authors： Boppana S,Kendall N,Akinrinsola O,White D,Patel K,Lawal H

更新日期：2017-03-16 00:00:00

abstract：:The depletion of dopamine in the striatum region and Lewy bodies are the hallmark characteristics of Parkinson's disease. The pathology also includes the upregulation of various Parkinson's disease (PARK) genes and kinases. Two such kinases, LRRK2 and GSK-3β have been directly implicated in the formation of tau and al...

journal_title：Neuroscience letters

authors： Kesh S,Kannan RR,Sivaji K,Balakrishnan A

更新日期：2021-01-01 00:00:00

abstract：:In membrane physiology, as in other fields, myths or speculations may be repeated so often and so widely that they are perceived as facts. To some extent, this has occurred with regard to gap junctions, hemichannels, pannexin channels and P2X7 (ionotropic receptors), especially concerning the interpretation of the ind...

journal_title：Neuroscience letters

authors： de Freitas PHM,da Silva Ferreira NC,Fioravante-Rezende JG,de Menezes Santos L,Alves LA,Rozental R

更新日期：2019-03-16 00:00:00

abstract：:We studied changes in the characteristics of action potentials of CA3 pyramidal cells accompanying electrographic seizure (EGS) induction, using an in vitro model similar to kindling. We found an increased propensity to fire action potentials which lack EPSPs or other triggering depolarizing potentials. Such 'baseline...

journal_title：Neuroscience letters

authors： Stasheff SF,Wilson WA

更新日期：1990-03-26 00:00:00

abstract：:Corticokinematic coherence (CKC), i.e., coherence calculated between MEG and an accelerometer signal, recording movement kinematics, can be used for functional mapping of the sensorimotor cortex. Cortical sources of CKC, induced by both voluntary and passive movements, localize at the proximity of sensorimotor cortex....

journal_title：Neuroscience letters

authors： Airaksinen K,Lehti T,Nurminen J,Luoma J,Helle L,Taulu S,Pekkonen E,Mäkelä JP

更新日期：2015-08-18 00:00:00

abstract：:Galanin- and bethanechol-activated whole cell currents were studied in dissociated mudpuppy parasympathetic neurons kept in 12.5 mM KCl. The bethanechol-induced current was reduced when generated during a galanin-induced current. The galanin and bethanechol currents reversed at -45 mV and exhibited inward rectificatio...

journal_title：Neuroscience letters

authors： Parsons RL,Merriam LA

更新日期：1992-06-08 00:00:00

abstract：:Nor-binaltorphimine (nor-BNI) is kappa opioid receptor (KOR) antagonist with the extremely long duration in mice analgesic assay, in vivo. For the evaluation of long-lasting effect of nor-BNI, brain content and serum concentration of nor-BNI were quantified in comparison with those of naloxone (a short-acting non-spec...

journal_title：Neuroscience letters

authors： Kishioka S,Kiguchi N,Kobayashi Y,Yamamoto C,Saika F,Wakida N,Ko MC,Woods JH

更新日期：2013-09-27 00:00:00

abstract：:We have used in situ hybridization with biotinylated oligonucleotide (antisense) probes and streptavidin-biotinylated alkaline phosphatase method to detect the amount of amyloid beta-protein mRNA in the paraffin-embedded and formalin-fixed brain samples of patients affected by Alzheimer's disease and those of non-affe...

journal_title：Neuroscience letters

authors： Syrjänen S,Heinonen O,Miettinen R,Paljärvi L,Syrjänen K,Riekkinen P

更新日期：1991-09-02 00:00:00

abstract：:Constant bright light (LL) suppresses 24-h melatonin and many other behavioral and physiological rhythms in pigeons. LL also strongly suppresses sleep. Daily melatonin infusions in LL restore sleep to normal nocturnal levels of a light-dark cycle and continuous infusions sustain it for at least 10 days. Restoration of...

journal_title：Neuroscience letters

authors： Phillips NH,Berger RJ

更新日期：1992-10-12 00:00:00

abstract：:The pattern of projection of the ventrobasal thalamic complex (VB) upon the neocortical barrel field of normal and reeler mutant mice was determined by orthograde degeneration experiments and by Timm's histochemical method. In both reeler and normal mice the thalamic terminals are concentrated at the midcortical zone ...

journal_title：Neuroscience letters

authors： Caviness VS Jr,Frost DO,Hayes NL

更新日期：1976-09-01 00:00:00

abstract：:Recent studies suggest that mild hypothermia significantly alleviate damage following cerebral ischemia though the precise mechanism is poorly defined. In the present study, middle cerebral artery occlusion (MCAo) was induced in Sprague-Dawley (SD) rats for 1 h followed by varying periods of reperfusion. Cerebral infa...

journal_title：Neuroscience letters

authors： Prakasa Babu P,Yoshida Y,Su M,Segura M,Kawamura S,Yasui N

更新日期：2000-09-22 00:00:00