Dispelling myths about connexins, pannexins and P2X7 in hypoxic-ischemic central nervous system.

abstract：:Patients with unilateral (n = 14) and bilateral (n = 4) herniorrhaphy participated in this study. With bilateral herniorrhaphy, at the end of the surgery, the wound was infiltrated with a solution of bupivacaine 0.5% and ketamine 0.3% on one side and a solution of bupivacaine 0.5% only, on the other. With unilateral h...

journal_title：Neuroscience letters

authors： Tverskoy M,Oren M,Vaskovich M,Dashkovsky I,Kissin I

更新日期：1996-08-30 00:00:00

abstract：:Experiments using functional magnetic resonance imaging (fMRI) play a fundamental role in affective neuroscience. When placed in an MR scanner, some volunteers feel safe and relaxed in this situation, while others experience uneasiness and fear. Little is known about the basis and consequences of such inter-individual...

journal_title：Neuroscience letters

authors： Mutschler I,Wieckhorst B,Meyer AH,Schweizer T,Klarhöfer M,Wilhelm FH,Seifritz E,Ball T

更新日期：2014-11-07 00:00:00

abstract：:Probiotics participate actively in the neuropsychiatric disorders. However, their roles on ischemic stroke remain unclear. This study aims to determine whether Clostridium butyricum (C. butyricum) could attenuate cerebral ischemia/reperfusion (I/R) injury and its possible mechanisms. Male ICR mice were intragastricall...

journal_title：Neuroscience letters

authors： Sun J,Ling Z,Wang F,Chen W,Li H,Jin J,Zhang H,Pang M,Yu J,Liu J

更新日期：2016-02-02 00:00:00

abstract：:Early life nutrition is critical for brain development. Dietary prebiotics and bioactive milk fractions support brain development by increasing plasticity and altering activity in brain regions important for cognition and emotion regulation, perhaps through the gut-microbiome-brain axis. Here we examined the impact of...

journal_title：Neuroscience letters

authors： Mika A,Gaffney M,Roller R,Hills A,Bouchet CA,Hulen KA,Thompson RS,Chichlowski M,Berg BM,Fleshner M

更新日期：2018-06-11 00:00:00

abstract：:The characteristics of long-term potentiation (LTP) in the hippocampus of rats prenatally exposed to ethanol and treated postnatally with nootropic compounds L-pyroglutamyl-D-alanine-amide (L-pGlu-D-AlaNH2, PGA) or piracetam were studied using in vitro slice preparations. LTP was induced in the CA1 region by the ortho...

journal_title：Neuroscience letters

authors： Chepkova AN,Doreulee NV,Trofimov SS,Gudasheva TA,Ostrovskaya RU,Skrebitsky VG

更新日期：1995-03-31 00:00:00

abstract：:myo-Inositol monophosphatase (E.C.3.1.3.25) catalyzes the hydrolysis of myo-inositol 1-phosphate in the presence of Mg2+ at a physiologic pH to form free myo-inositol, maintaining a supply that represents the precursor for inositol phospholipid second messenger signaling systems. In the present study the activity and ...

journal_title：Neuroscience letters

authors： Shimohama S,Tanino H,Sumida Y,Tsuda J,Fujimoto S

更新日期：1998-04-10 00:00:00

abstract：:The distribution of L-3,4-dihydroxy-[3H]phenylalanine (L-[3H]DOPA) was examined in rats following i.v. injection, to ascertain the possible usefulness of using this ligand to image dopaminergic systems using positron emission tomography. It was found that L-DOPA and its metabolites were preferentially localized in the...

journal_title：Neuroscience letters

authors： Liskowsky DR,Potter LT

更新日期：1985-01-21 00:00:00

abstract：:Regular physical activity benefits brain health and function. Physical activity performed by young adults is declining. However, the influence of diminished physical activity on cognitive performance and motor preparation in young adults remains unclear. This study measured changes in behavior and brain activity durin...

journal_title：Neuroscience letters

authors： Cirillo J,Finch JB,Anson JG

更新日期：2017-01-18 00:00:00

abstract：:Prominent accounts of decision making state that decisions are made on the basis of an accumulation of sensory evidence, orchestrated by networks of prefrontal and parietal neural populations. Here we assess whether these findings generalize to decisions on self-motion. Participants were presented with whole body yaw ...

journal_title：Neuroscience letters

authors： de Winkel KN,Nesti A,Ayaz H,Bülthoff HH

更新日期：2017-07-27 00:00:00

abstract：:The role of serotonin (5-hydroxytryptamine, 5-HT)-mediated modulation of phrenic motoneuronal activity was evaluated by microapplication of 5-HT and methysergide into the phrenic nuclei of the rabbit. 5-HT facilitated phrenic nerve activity (PNA) considerably resulting in a long-lasting augmentation of the peak amplit...

journal_title：Neuroscience letters

authors： Schmid K,Böhmer G,Merkelbach S

更新日期：1990-08-14 00:00:00

abstract：:Prefoldin is a molecular chaperone that assists the folding of newly synthesized polypeptide chains and prevents aggregation of misfolded proteins. Dysfunction of prefoldin is one of the causes of neurodegenerative diseases such as Alzheimer's disease. The aim of this study was to clarify the involvement of prefoldin ...

journal_title：Neuroscience letters

authors： Kadoyama K,Matsuura K,Takano M,Maekura K,Inoue Y,Matsuyama S

更新日期：2019-11-01 00:00:00

abstract：:Despite much study since its discovery in 1995, the effects of orphanin FQ/nociceptin (OFQ/N), the endogenous ligand of the 'orphan' opioid receptor, on nociceptive sensitivity remain unclear. Different laboratories have variously reported hyperalgesic, analgesic, anti-analgesic or no effect of the peptide on thermal ...

journal_title：Neuroscience letters

authors： Mogil JS,Nessim LA,Wilson SG

更新日期：1999-02-19 00:00:00

abstract：:Tetrahydroaminoacridine (THA) has recently been reported to be more useful in the treatment of Alzheimer's disease than physostigmine. A comparison of the effects of these two anticholinesterase agents on in vitro enzyme and receptor activities of human cerebral cortex (obtained at autopsy) revealed similarities in th...

journal_title：Neuroscience letters

authors： Perry EK,Smith CJ,Court JA,Bonham JR,Rodway M,Atack JR

更新日期：1988-08-31 00:00:00

abstract：:Mammals navigate a complex environment using a variety of strategies, which can operate in parallel and even compete with one another. We have recently described a variant water maze task in which two of these strategies, hippocampus-dependent spatial learning and striatum-dependent cued learning, can be dissociated. ...

journal_title：Neuroscience letters

authors： Baldan Ramsey LC,Pittenger C

更新日期：2010-10-11 00:00:00

abstract：:The localization of luteinizing hormone-releasing hormone (LH-RH) has been studied in the human brain with the indirect immunofluorescence technique. LH-RH positive perikarya are scattered from the septo-preoptic region up to the retromammillary area and give rise to two main tracts ending in the infundibulum and the ...

journal_title：Neuroscience letters

authors： Barry J

更新日期：1976-12-01 00:00:00

abstract：:Numerous studies have provided evidence for a genetic association of the Apolipoprotein E (ApoE) epsilon4 allele and late onset familial and sporadic Alzheimer's disease (AD). Clinical observations show that a proportion of schizophrenic patients may suffer from severe cognitive impairment. That could reflect a partic...

journal_title：Neuroscience letters

authors： Sorbi S,Nacmias B,Tedde A,Latorraca S,Forleo P,Guarnieri BM,Petruzzi C,Daneluzzo E,Ortenzi L,Piacentini S,Amaducci L

更新日期：1998-03-13 00:00:00

abstract：:The possibility that single electrical shock stimulation of somatic afferent nerves could evoke a reflex response in vagal efferent nerves innervating the stomach was examined using anesthetized, artificially-ventilated rats. A single shock to a hindlimb afferent nerve (tibial nerve) produced two distinct reflex compo...

journal_title：Neuroscience letters

authors： Kimura A,Sato A,Sato Y,Suzuki A

更新日期：1996-05-24 00:00:00

abstract：:The effect of different frequencies of music on brain function was investigated through measurement of blood pressure in spontaneously hypertensive rats (SHR). Previous studies indicated that exposure to Mozart's music (K. 205) leads to increased calcium/calmodulin-dependent dopamine synthesis in the brain, and that t...

journal_title：Neuroscience letters

authors： Akiyama K,Sutoo D

更新日期：2011-01-03 00:00:00

abstract：:Parkinson disease (PD) features profound striatal dopamine depletion and Lewy bodies containing abundant precipitated alpha-synuclein. Mechanisms linking alpha-synucleinopathy with the death of dopamine neurons remain incompletely understood. One such link may be 3,4-dihydroxyphenylacetaldehyde (DOPAL). All of the int...

journal_title：Neuroscience letters

authors： Jinsmaa Y,Sullivan P,Gross D,Cooney A,Sharabi Y,Goldstein DS

更新日期：2014-05-21 00:00:00

abstract：:The influence of insulin on the infarct volume due to middle cerebral artery (MCA) occlusion was investigated in rats. A small dose of insulin (1 unit/kg) was injected i.p. just after MCA occlusion. The infarct areas were measured by planimetry from brains perfused with 2,3,5-triphenyltetrazolium-chloride (TTC) 48 h a...

journal_title：Neuroscience letters

authors： Izumi Y,Pinard E,Roussel S,Seylaz J

更新日期：1992-09-14 00:00:00

abstract：:Ibotenate induced a concentration- and largely calcium-dependent release of endogenous glutamate from guinea pig cerebro-cortical synaptosomes. In the absence of Mg2+, the response to ibotenate was enhanced through a mechanism involving N-methyl-D-aspartate (NMDA) receptors; this component was sensitive to the NMDA an...

journal_title：Neuroscience letters

authors： Jones PG,Roberts PJ

更新日期：1990-03-26 00:00:00

abstract：:It is debated whether non-affected relatives of patients with affective disorders share a specific brain structure endophenotype. Aim of this work is to explore the medial temporal morphology in affected and non-affected members of a family with mood disorders. Hippocampi and amygdalae were manually traced from the 3D...

journal_title：Neuroscience letters

authors： Boccardi M,Almici M,Bresciani L,Caroli A,Bonetti M,Monchieri S,Gennarelli M,Frisoni GB

更新日期：2010-01-04 00:00:00

abstract：:Spinocerebellar ataxias (SCAs) are a group of clinically and genetically heterogeneous neurological diseases. The expansion of unstable microsatellite repeats has been identified as the underlying pathogenic cause of 10 subtypes of autosomal dominant SCAs. The aetiology of sporadic SCA is unknown. The aim of this stud...

journal_title：Neuroscience letters

authors： Majounie E,Wardle M,Muzaimi M,Cross WC,Robertson NP,Williams NM,Morris HR

更新日期：2007-12-11 00:00:00

abstract：:Perceptions of facial attractiveness are sensitive to emotional expression of the perceived face. However, little is known about whether the emotional expression on the face of another observer of the perceived face may have an effect on perceptions of facial attractiveness. The present study used event-related potent...

journal_title：Neuroscience letters

authors： Huang Y,Pan X,Mo Y,Ma Q

更新日期：2016-03-23 00:00:00

abstract：:The influence of transient forebrain ischemia on the temporal alteration of NMDA receptor (NMDAR1) mRNAs in the hippocampal formation was analysed by in situ hybridization, RNA blot and in vitro receptor autoradiography ([3H]3-((+)2-carboxypiperazin-4-yl)-propyl-1- phosphonic acid). In the CA1 subfield of the hippocam...

journal_title：Neuroscience letters

authors： Sugimoto A,Takeda A,Kogure K,Onodera H

更新日期：1994-03-28 00:00:00

abstract：:We looked for an interaction between etifoxine and the neurosteroid allopregnanolone at central gamma-aminobutyric acid (GABA(A)) receptors. Etifoxine (2 microM) did not affect the affinity of allopregnanolone (IC(50)=108 nM) for its site in preparations of Sprague-Dawley rat cerebral cortex membranes, as determined b...

journal_title：Neuroscience letters

authors： Verleye M,Schlichter R,Neliat G,Pansart Y,Gillardin JM

更新日期：2001-04-06 00:00:00

abstract：:Effects of intrathecally (i.t.) administered R-phenylisopropyl adenosine (R-PIA), an adenosine A1 receptor agonist, on presumed pain behaviour were assessed in a rat model of chronic central pain. Spinal cord injury was induced photochemically via laser irradiation of the spinal cord after intravenous injection of ery...

journal_title：Neuroscience letters

authors： Sjölund KF,von Heijne M,Hao JX,Xu XJ,Sollevi A,Wiesenfeld-Hallin Z

更新日期：1998-02-27 00:00:00

abstract：:To evaluate the roles of complement in kainic acid (KA)-induced neuronal damages, the immunohistochemical localization of the complement protein C3 was examined in rat hippocampus after systemic KA injection. The immunoreactivity for C3 was found in glial cells in control rats, and such glial cells were increased in n...

journal_title：Neuroscience letters

authors： Morita H,Suzuki K,Mori N,Yasuhara O

更新日期：2006-11-27 00:00:00

abstract：:Previous evidence has shown expression of synaptophysin by sensory cells of the auditory and vestibular systems in the human, but not in other mammalian species. Using a monoclonal antibody, SBI 20.10, we investigated the expression of synaptophysin in the sensory cells of the avian cochlea. We present immunohistochem...

journal_title：Neuroscience letters

authors： Sokolowski BH,Cunningham AM

更新日期：1996-09-27 00:00:00

abstract：:We investigated the relation between visual feedback and the degree of structure versus randomness in the variability of single-digit, isometric force output. Participants were instructed to maintain a constant level of force during the presence or absence of visual feedback about force output. The structure of force ...

journal_title：Neuroscience letters

authors： Athreya DN,Van Orden G,Riley MA

更新日期：2012-03-28 00:00:00