Sensory cells of the chick cochlea express synaptophysin.

Abstract:

:Previous evidence has shown expression of synaptophysin by sensory cells of the auditory and vestibular systems in the human, but not in other mammalian species. Using a monoclonal antibody, SBI 20.10, we investigated the expression of synaptophysin in the sensory cells of the avian cochlea. We present immunohistochemical data showing synaptophysin expression by cochlear hair cells in both late stage embryos and adult chickens. Immunoblotting of cochleae confirmed an antigen with an apparent molecular weight appropriate for synaptophysin that increases with development. Immunoreactivity in the apex of the cochlea occurred in hair cells on both neural and abneural sides, whereas immunoreactivity in the base of the cochlea was relegated to hair cells on the neural side. These observations indicate that, in the avian auditory system, like the human, synaptophysin is expressed in the sensory cells of both the embryo and adult.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Sokolowski BH,Cunningham AM

doi

10.1016/0304-3940(96)13017-2

subject

Has Abstract

pub_date

1996-09-27 00:00:00

pages

89-92

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(96)13017-2

journal_volume

216

pub_type

杂志文章
  • Riluzole improves functional recovery after acute spinal cord injury in rats and may be associated with changes in spinal microglia/macrophages polarization.

    abstract::Spinal cord injury (SCI) triggers pronounced inflammatory responses that are accompanied by neuronal disruption and functional deficits. SCI treatment remains an unmet clinical need. Emerging evidence suggests that riluzole may exert a neuroprotective effect due to its anti-inflammatory properties. However, details of...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2020.134829

    authors: Wu Q,Zhang Y,Zhang Y,Zhang W,Zhang W,Liu Y,Xu S,Guan Y,Chen X

    更新日期:2020-04-01 00:00:00

  • Seasonal variations of the beta-endorphin neuronal system in the mediobasal hypothalamus of the jerboa (Jaculus orientalis).

    abstract::The distribution of neurons expressing beta-endorphin immunoreactivity was explored in the brain of adult jerboa during two distinct periods characterizing its reproductive cycle. A large presence of cell bodies displaying beta-endorphin immunoreactivity occured within different parts of the mediobasal hypothalamus al...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.11.035

    authors: El Ouezzani S,Tramu G,Magoul R

    更新日期:2005-03-11 00:00:00

  • Central myelin gene expression during postnatal development in rats exposed to nicotine gestationally.

    abstract::Abnormal myelin gene expression in the central nervous system (CNS) is associated with many mental illnesses, including psychiatric disorders and drug addiction. We have previously shown that prenatal exposure to nicotine, the major psychoactive component in cigarette smoke, alters myelin gene expression in the CNS of...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2013.08.012

    authors: Cao J,Dwyer JB,Gautier NM,Leslie FM,Li MD

    更新日期:2013-10-11 00:00:00

  • Effects of irradiation on the sensitivity of melatonin release to norepinephrine in cultured pineal bodies of rats.

    abstract::We measured levels of basal and norepinephrine (NE) -induced melatonin release in cultured pineal bodies of rats just after and 2 days after irradiation (20 or 200 Gy) or sham-irradiation. On the day of irradiation, basal and NE-induced melatonin release were not affected by irradiation. Two days after irradiation, ba...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)00984-8

    authors: Saito K,Shinohara K,Morofushi M,Funabashi T,Mitsushima D,Hata M,Matsubara S,Kimura F

    更新日期:2000-04-21 00:00:00

  • Sex-dependent effects of long-term oral methylphenidate treatment on spontaneous and learned fear behaviors.

    abstract::In previous studies, chronic low-dose methylphenidate (MPH) administration during early development has been shown to increase emotional responding in adulthood. However, most studies employed male subjects, which generally show enhanced fear relative to females in laboratory tests of anxious behaviors. The present st...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2011.03.080

    authors: Bethancourt JA,Vásquez CE,Britton GB

    更新日期:2011-05-27 00:00:00

  • Expression of nuclear Methyl-CpG binding protein 2 (Mecp2) is dependent on neuronal stimulation and application of Insulin-like growth factor 1.

    abstract::Methyl-CpG binding protein 2 (MECP2) is a chromosome-binding protein that regulates the development and maintenance of brain circuits. Altered function of the protein product of MECP2 plays an important role in the etiology of many neurodevelopmental disorders. Mutations involving a loss of function are implicated in ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2016.04.024

    authors: Tropea D,Mortimer N,Bellini S,Molinos I,Sanfeliu A,Shovlin S,McAllister D,Gill M,Mitchell K,Corvin A

    更新日期:2016-05-16 00:00:00

  • Role of alpha 1 and alpha 2-adrenoceptors of the lateral hypothalamic area on urinary excretion caused by centrally administered angiotensin II.

    abstract::To determine whether central alpha 1 and alpha 2-adrenergic mechanisms are involved in urinary sodium and potassium excretion and urine volume induced by angiotensin II (ANGII), these renal parameters were measured in volume-expanded Holtzman rats with cannulas implanted into lateral ventricle (LV) and lateral hypotha...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)11751-h

    authors: Saad WA,Camargo LA,Renzi A,Menani JV,Saad WA

    更新日期:1995-07-21 00:00:00

  • Immunocytochemical distribution of the protein kinase C substrate B-50 (GAP43) in developing rat pyramidal tract.

    abstract::The neuron-specific phosphoprotein B-50 is a major substrate of kinase C in fetal nerve growth cones, neonatal neural and synaptosomal plasma membranes. B-50 is identical to a growth-associated protein GAP43. Similarly, increases in B-50 occur during rat brain development, neuronal differentiation and axon regeneratio...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(87)90216-3

    authors: Gorgels TG,Oestreicher AB,de Kort EJ,Gispen WH

    更新日期:1987-12-16 00:00:00

  • Expression of estrogen receptor-alpha and beta mRNA in the developing and adult mouse striatum.

    abstract::Estrogen not only modulates nigrostriatal function but also developmental processes in the striatum. Recently, we have demonstrated the presence of the estrogen-synthesizing enzyme aromatase in the developing mouse striatum. This study is concerned with the expression of estrogen receptor-alpha/beta (ER) mRNA in the d...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00815-0

    authors: Küppers E,Beyer C

    更新日期:1999-12-03 00:00:00

  • NMDAR blockade-induced neonatal brain injury: Reversal by the calcium channel agonist BayK 8644.

    abstract::We have previously shown that P7 rat pups injected with the N-methyl-d-aspartate receptor (NMDAR) blocker MK801 displayed robust apoptotic injury within hours after injection. Further studies from our lab suggest that loss of calcium cannot be compensated for when vulnerable neurons lack calcium buffering capabilities...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.12.002

    authors: Turner CP,Debenedetto D,Liu C

    更新日期:2009-02-06 00:00:00

  • Acute single dose of ketamine relieves mechanical allodynia and consequent depression-like behaviors in a rat model.

    abstract::Both chronic pain and depression are debilitating diseases, which often coexist in clinic. However, current analgesics and antidepressants exhibit limited efficacy for this comorbidity. The present study aimed to investigate the effect of ketamine on the comorbidity of inflammatory pain and consequent depression-like ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2016.08.006

    authors: Zhang GF,Wang J,Han JF,Guo J,Xie ZM,Pan W,Yang JJ,Sun KJ

    更新日期:2016-09-19 00:00:00

  • Presynaptic displacement of serotonin by alpha-methyl-5-hydroxytryptamine in the nucleus tractus solitarius of the rat.

    abstract::Rat brain slices containing the nucleus tractus solitarius loaded with [3H]5-hydroxytryptamine ([3H]5-HT) for superfusion were stimulated at (3 Hz, 25 mA, 1 min) resulting in fractional release ratios S2/S1 of 0.89 for [3H]5-HT in the presence of the serotonin uptake inhibitor 1.0 microM 6-nitroquipazine (6-NQ). alpha...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)11450-b

    authors: Helfman CC,Anderson GF,Barraco RA

    更新日期:1995-04-14 00:00:00

  • Biphasic effects of exogenous VEGF on VEGF expression of adult neural progenitors.

    abstract::Vascular endothelial growth factor (VEGF) regulates neurogenesis. The present study investigated the direct effect of VEGF on the enhancement of proliferation and differentiation of the adult mouse subventricular zone (SVZ) neural progenitors in vitro. A high dose (500 ng/ml) of VEGF significantly downregulated endoge...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2005.09.044

    authors: Meng H,Zhang Z,Zhang R,Liu X,Wang L,Robin AM,Chopp M

    更新日期:2006-01-30 00:00:00

  • Dynamics of directed interactions between brain regions during interburst-burst EEG patterns in quiet sleep of full-term neonates.

    abstract::The study investigates time-variant directed interactions between brain regions during the interburst-burst EEG pattern (tracé alternant) characteristic of quiet sleep in healthy neonates. The transition from interburst to burst is of particular interest as the generation of the EEG characteristics at burst onset refl...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.11.018

    authors: Milde T,Putsche P,Schwab K,Wacker M,Eiselt M,Witte H

    更新日期:2011-01-20 00:00:00

  • Peripheral nerve cells in culture rich in Schwann cells incorporate and metabolize trans-unsaturated fatty acid (elaidic acid) as well as physiological dis isomer (oleic acid).

    abstract::A culture of peripheral nerve cells enriched in Schwann cells was obtained from sciatic nerve in normal and demyelinating trembler mutant. These cells incorporated and metabolized a non-physiological trans fatty acid (elaidic aid) as well as the physiological cis isomer (oleic acid). Both acids were incorporated simil...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(82)90292-0

    authors: Bourre JM,Boutry JM,Masson M,Hauw JJ

    更新日期:1982-05-28 00:00:00

  • A study of GABAergic system in Scrapie-infected hamsters after striatal microinoculation of the agent.

    abstract::Experimental Scrapie in hamster is a simple, reproducible model of prion diseases that occur in humans and animals. Stereotaxic microinoculation (0.5 microliter) of the agent (263 K) into a specific cerebral structure (striatum) in hamster, previously developed in our group, gives the opportunity to further investigat...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(93)90366-s

    authors: Grégoire N,Lebrun F,Fahn L,Salamon G,Nicoli J

    更新日期:1993-12-12 00:00:00

  • Presynaptic involvement in frequency facilitation in the hippocampal slice.

    abstract::Orthodromic stimulation with frequencies from 1 to 30 Hz causes facilitation of extracellularly recorded population spikes and a decrease of extracellular Ca2+ concentration ( [Ca2+]o ) monitored with ion selective microelectrodes at the cell body layer of area CA1 of the hippocampal slice. Reducing the Ca2+ content o...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(83)90271-9

    authors: Konnerth A,Heinemann U

    更新日期:1983-12-11 00:00:00

  • Bilateral temporal cortex transcranial direct current stimulation worsens male performance in a multisensory integration task.

    abstract::Somatosensory integration is a critical cognitive function for human social interaction. Though somatosensory integration has been highly explored in cognitive studies; only a few studies have explored focal modulation of cortical excitability using a speech perception paradigm. In the current study, we aimed to inves...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.08.076

    authors: Lapenta OM,Fregni F,Oberman LM,Boggio PS

    更新日期:2012-10-11 00:00:00

  • Pre-attentive processing of auditory patterns in dyslexic human subjects.

    abstract::It has been hypothesized that auditory temporal processing plays a major role in the aetiology of dyslexia. Event-related brain potentials (mismatch negativity, MMN) of auditory temporal processing were assessed in 15 dyslectic adults and 20 controls. A complex tonal pattern was used where the difference between stand...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00785-5

    authors: Schulte-Körne G,Deimel W,Bartling J,Remschmidt H

    更新日期:1999-11-26 00:00:00

  • Effect of the 1-methyl-4-phenylpyridinium ion on phosphorylation of tyrosine hydroxylase in rat pheochromocytoma PC12h cells.

    abstract::Effects of the 1-methyl-4-phenylpyridinium ion (MPP+) on DOPA formation and phosphorylation of tyrosine hydroxylase (TH) of rat pheochromocytoma PC12h cells were examined after the cells were cultured with MPP+. DOPA formed from endogenous tyrosine in PC12h cells after a 3-day culture with 100 microM MPP+ was decrease...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(88)90383-7

    authors: Kiuchi K,Hagiwara M,Hidaka H,Nagatsu T

    更新日期:1988-06-29 00:00:00

  • Lucifer yellow stains displaced amacrine cells of the chicken retina during embryonic development.

    abstract::We have used Lucifer Yellow for histological tracing of displaced amacrine cells within the ganglion cell layer (GCL) during the embryonic development of the chicken retina. Incubating whole eyes in the dye leads to bright staining of all displaced amacrine cells, whereas ganglion cells and glial cells are not stained...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(82)90099-4

    authors: Layer PG,Vollmer G

    更新日期:1982-08-16 00:00:00

  • Transient acidosis induces delayed neurotoxicity in cultured hippocampal slices.

    abstract::It remains unknown if tissue acidosis contributes to neuronal loss during cerebral ischemia. We report that brief intracellular acidification (pH 6.62) results in delayed neuronal loss in cultured hippocampal slices. Cell loss was located primarily in stratum pyramidale and the hilus suggesting that neurons were prefe...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)11238-e

    authors: Shen H,Chan J,Kass IS,Bergold PJ

    更新日期:1995-02-09 00:00:00

  • Hippocampal kindling leads to different changes in paired-pulse depression of local evoked field potentials in CA1 area and in fascia dentata.

    abstract::Monosynaptic evoked field potentials (EPs) in response to paired-pulse stimulation (20 ms interval) were recorded in area CA1 and fascia dentata of the same animal in the course of development of a kindled focus in the CA1 region. A significant reduction of paired pulse depression in response to medium and high stimul...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90344-7

    authors: Kamphuis W,Gorter JA,Wadman WJ,Lopes da Silva FH

    更新日期:1992-07-06 00:00:00

  • Abnormal functional connectivity of motor circuit in the schizophrenic patients with tardive dyskinesia: A resting-state fMRI study.

    abstract:BACKGROUND:Animal and neuroimaging studies suggest that the volume of the motor-circuit region decreases in tardive dyskinesia (TD). This study examined the differences in functional connectivity within the motor circuit of patients with schizophrenia with and without TD to further clarify how the dysfunction is relate...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2020.135548

    authors: Yu T,Li Y,Li N,Huang J,Fan F,Luo X,Tan S,Yang F,Tian B,Tian L,Elliot Hong L,Tan Y

    更新日期:2021-01-18 00:00:00

  • Stimulation of synaptosomal D-[(3)H]aspartate transport by substance P in rat brain.

    abstract::The effect of the neuropeptide, substance P, on the transport of D-[(3)H]aspartate into rat striatal synaptosomes was studied. Almost 90% of the total transport of D-[(3)H]aspartate was sodium-dependent and the maximum rate (V(max)) of this transport was increased by 34% of control by 2.5 nM substance P (EC(50)=0.52 n...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01318-5

    authors: Healy J,Downes A,McBean GJ

    更新日期:2000-08-25 00:00:00

  • Antagonism of non-cholinergic excitatory junction potentials in the guinea-pig ileum by a substance P analogue antagonist.

    abstract::In the presence of atropine electrical transmural stimulation (using repetitive volleys, e.g. 3 pulses at 50 Hz applied every 4 s) of full thickness longitudinal strips of guinea-pig ileum produced non-cholinergic excitatory junction potentials (EJPs) and inhibitory junction potentials (IJPs) in the circular muscle la...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90006-6

    authors: Taylor GS,Bywater RA

    更新日期:1986-01-02 00:00:00

  • Biphasic effects of chlorpromazine on cell viability in a neuroblastoma cell line.

    abstract::Although chlorpromazine was shown to greatly inhibit a Ca2+-mediated cell death at favorable concentrations (10(-6)-10(-5) M), it caused a drastic decrease in cell viability at higher concentrations (10(-4)-10(-3) M) in a human neuroblastoma cell line. The toxic effect of chlorpromazine also occurred in Ca2+-free medi...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90643-9

    authors: Abe K,Sekizawa T,Kogure K

    更新日期:1986-11-21 00:00:00

  • Hypotonic diuresis following oropharyngeal stimulation with water in humans.

    abstract::The role of oropharyngeal mechanisms in body water regulation was studied in 12 human males by measuring urine output and osmolality before and after drinking a very small volume of distilled water (0.15 ml/kg b.w.t.). Hypotonic diuresis was resulted only in the subjects (n = 6) who drank only sufficient water to keep...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90792-1

    authors: Akaishi T,Shingai T,Miyaoka Y,Homma S

    更新日期:1989-12-15 00:00:00

  • Visual-vestibular conflict induced by virtual reality in humans.

    abstract::Conflicting inputs from visual and vestibular afferents produce motion sickness and postural instability. However, the relationship of visual and vestibular inputs to each other remains obscure. In this study, we examined the development of subjective sickness- and balance-related symptoms and objective equilibrium at...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(03)00098-3

    authors: Akiduki H,Nishiike S,Watanabe H,Matsuoka K,Kubo T,Takeda N

    更新日期:2003-04-17 00:00:00

  • Up-regulation of Hrk, a regulator of cell death, in retinal ganglion cells of axotomized rat retina.

    abstract::Hrk, a regulator of cell death, belongs to the family of pro-apoptotic BH3-only proteins and is known to induce apoptosis in nerve tissue. We examined Hrk gene expression to clarify the role of BH3-only proteins in apoptosis of retinal ganglion cells (RGCs) after optic nerve transection in the adult rat. Reverse trans...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)02487-9

    authors: Wakabayashi T,Kosaka J,Hommura S

    更新日期:2002-01-25 00:00:00