Induction of giant depolarizing potentials by zinc in area CA1 of the rat hippocampus does not result from block of GABAB receptors.

abstract：:Using a specific radioimmunoassay (RIA), we have quantitated the hypothalamic and extrahypothalamic distribution of vasoactive intestinal polypeptide (VIP) in the rat brain. Highest concentrations of VIP were found in cerebral cortex, suprachiasmatic nucleus, and medial amygdaloid nucleus. Lower concentrations were fo...

journal_title：Neuroscience letters

authors： Samson WK,Said SI,McCann SM

更新日期：1979-05-01 00:00:00

abstract：:Changes in cytokine and chemokine expression during Wallerian degeneration have been studied using nerve transection models, which result in denervation of both myelinating and non-myelinating Schwann cells. Cytokine and chemokine response of non-myelinating Remak Schwann cells to loss of their axons is unknown. In th...

journal_title：Neuroscience letters

authors： Cheepudomwit T,Güzelsu E,Zhou C,Griffin JW,Höke A

更新日期：2008-01-17 00:00:00

abstract：:The present study shows that cultured fibroblasts from sporadic Alzheimer's disease patients are deficient in protein kinase C-regulated secretion of amyloid precursor protein. In particular, Alzheimer fibroblasts show a reduced basal secretion and a reduced response at low concentrations of phorbol-12,13-dibutyrate, ...

journal_title：Neuroscience letters

authors： Bergamaschi S,Binetti G,Govoni S,Wetsel WC,Battaini F,Trabucchi M,Bianchetti A,Racchi M

更新日期：1995-12-01 00:00:00

abstract：:The regional cerebral blood flow (rCBF) was measured with positron emission tomography in eight normal volunteers with the purpose of measuring rCBF changes related to the comprehension of an unfamiliar spoken languages. When attempting to comprehend the meaning of words, the left hemisphere showed dominant increases ...

journal_title：Neuroscience letters

authors： Kawashima R,Itoh M,Hatazawa J,Miyazawa H,Yamada K,Matsuzawa T,Fukuda H

更新日期：1993-10-14 00:00:00

abstract：:gamma-Interferon (IFN-gamma) is known to induce expression of major histocompatibility complex (MHC) class II antigens on murine astrocytes and MHC class I antigens on murine oligodendrocytes. We studied whether the human IFN-gamma could induce the expression of Human Leukocyte Antigen (HLA)-A, B, C and -DR antigens o...

journal_title：Neuroscience letters

authors： Hirayama M,Yokochi T,Shimokata K,Iida M,Fujiki N

更新日期：1986-12-23 00:00:00

abstract：:Recently, Monfils et al. [9] and Clem and Huganir [3] have shown that an isolated retrieval trial before the extinction sessions (retrieval-extinction) in mice and rats prevented the renewal and spontaneous recovery of the original fear memory by inhibiting reconsolidation in a hippocampus-independent manner. In contr...

journal_title：Neuroscience letters

authors： Ishii D,Matsuzawa D,Matsuda S,Tomizawa H,Sutoh C,Shimizu E

更新日期：2012-08-08 00:00:00

abstract：:Procedural learning refers to the acquisition of motor skills and the practice that refines their performance. The striatum participates in this learning through a function regulated by endocannabinoid signaling and other systems. This study relates the efficiency in learning a procedural task with the AATn polymorphi...

journal_title：Neuroscience letters

authors： Ruiz-Contreras AE,Delgado-Herrera M,García-Vaca PA,Almeida-Rosas GA,Soria-Rodríguez G,Soriano-Bautista A,Cadena-Valencia J,Bazán-Frías JR,Gómez-López N,Espejel-Núñez A,Vadillo-Ortega F,Carrillo-Sánchez K,Verdín-Reyes JC,March-M

更新日期：2011-05-02 00:00:00

abstract：:Recordings from the intact nervus terminalis with a hook electrode or from a stump of the divided nerve with a suction electrode show a tonic, irregular discharge of broad, low frequency spikes in ca. 4-6 units. These nerve impulses are efferent from the brain. The mean frequency of discharge is not influenced by vari...

journal_title：Neuroscience letters

authors： Bullock TH,Northcutt RG

更新日期：1984-02-10 00:00:00

abstract：:Methamphetamine (METH) is one of the most commonly abused substances in today's society. Many studies have shown that the process of cell death induced by METH involves with the reception of death signals, an increase in pro-apoptotic proteins (Bax) and an activation of cysteine protease death pathway. The objective o...

journal_title：Neuroscience letters

authors： Chetsawang J,Suwanjang W,Pirompul N,Govitrapong P,Chetsawang B

更新日期：2012-01-06 00:00:00

abstract：:We have previously shown that D-cycloserine displaces [3H]glycine binding to a recognition site with properties consistent with an N-methyl-D-aspartate (NMDA) receptor modulatory site. Additionally, D-cycloserine positively modulates the NMDA receptor as evidenced by its dose-dependent enhancement of [3H]1-[1-(2-thien...

journal_title：Neuroscience letters

authors： Hood WF,Compton RP,Monahan JB

更新日期：1989-03-13 00:00:00

abstract：:Intracellular and extracellular recordings were obtained from layers II-III of slices of adult rat neocortex maintained in vitro. Excitatory postsynaptic potentials (EPSPs) and epileptiform discharges (paroxysmal depolarizing shifts, PDSs) were evoked in the presence of bicuculline methiodide. Responses were monitored...

journal_title：Neuroscience letters

authors： Burke JP,Hablitz JJ

更新日期：1994-06-06 00:00:00

abstract：:The localization of amyloid beta protein (A beta), A beta 40, A beta 42, and transthyretin (TTR) was investigated immunohistochemically in the autopsied human kidney, using polyclonal antibodies against TTR, A beta and C-terminal end-specific antibodies against A beta 40 and 42. Immunoreactivities of A beta and A beta...

journal_title：Neuroscience letters

authors： Tsuzuki K,Fukatsu R,Hayashi Y,Yoshida T,Sasaki N,Takamaru Y,Yamaguchi H,Tateno M,Fujii N,Takahata N

更新日期：1997-02-07 00:00:00

abstract：:Following unilateral transection of the medial forebrain bundle (MFB) within the anterior hypothalamic-preoptic region of cats, the biting attack upon a rat elicited by ipsilateral posterior hypothalamic or ventral midbrain stimulation is eliminated, although the cat continues to approach from 2.8 metres away to withi...

journal_title：Neuroscience letters

authors： Halliday R,Bandler R

更新日期：1981-01-20 00:00:00

abstract：:Emotional processing in coma remains an open question. Skin conductance responses to emotional and neutral auditory stimuli were recorded in 13 low-responsive patients (12 of whom were in coma). A differential response between emotional and neutral stimuli was found, which significantly correlated with the Glasgow Com...

journal_title：Neuroscience letters

authors： Daltrozzo J,Wioland N,Mutschler V,Lutun P,Calon B,Meyer A,Jaeger A,Pottecher T,Kotchoubey B

更新日期：2010-05-07 00:00:00

abstract：:Although the guinea pig is used widely in experimental medical research, including in studies on micturition control, the spinal origin of preganglionic parasympathetic bladder and somatic external urethral sphincter motoneurons is not known. In the male guinea pig using wheat germ agglutinin-conjugated horseradish pe...

journal_title：Neuroscience letters

authors： Kuipers R,Izhar Z,Gerrits PO,Miner W,Holstege G

更新日期：2004-05-13 00:00:00

abstract：:The interaction between ATP-activated channels and the nicotinic receptor-channels has been reported in neuronal cells. To elucidate the mechanisms underlying the interaction, the currents activated by ATP and acetylcholine (ACh) were recorded from cell-free membrane patches excised from rat sympathetic neurons. When ...

journal_title：Neuroscience letters

authors： Nakazawa K,Inoue K

更新日期：1993-11-26 00:00:00

abstract：:The co-localization of neuropeptide tyrosine (NPY) and somatostatin (SOM) in rat hippocampal cells was studied in double labelling experiments using a combination of antibodies against the two peptides on the same tissue section. The individual hippocampal subfields show large variations in the relative number of NPY-...

journal_title：Neuroscience letters

authors： Köhler C,Eriksson LG,Davies S,Chan-Palay V

更新日期：1987-07-09 00:00:00

abstract：:Amyloid beta-peptide (Abeta) deposition in brain is important in the development of Alzheimer's disease (AD). Neprilysin (NEP) appears to be the major Abeta degrading enzyme in vivo and reduced mRNA levels of NEP correlates with increased plaque density. We hypothesized that alterations in the NEP promoter region may ...

journal_title：Neuroscience letters

authors： Lilius L,Forsell C,Axelman K,Winblad B,Graff C,Tjernberg L

更新日期：2003-02-06 00:00:00

abstract：:Extracellular noradrenaline was measured on-line in the cerebral cortex of the freely moving rat by microdialysis coupled to high performance liquid chromatography and electrochemical detection. High potassium concentrations in the perfusion fluid led to a strong increase, whereas tetrodotoxin led to almost undetectab...

journal_title：Neuroscience letters

authors： van Veldhuizen MJ,Feenstra MG,Boer GJ,Westerink BH

更新日期：1990-11-13 00:00:00

abstract：:We have investigated the presence of mutations in the parkin gene in patients with early-onset parkinsonism. Direct sequencing of the polymerase chain reaction (PCR) products showed a homozygous G deletion in the exon 7 (c.871delG) in one patient. This was a 38-year-old Moroccan woman with a history of parkinsonism of...

journal_title：Neuroscience letters

authors： Muñoz E,Pastor P,Martí MJ,Oliva R,Tolosa E

更新日期：2000-07-28 00:00:00

abstract：:Many biochemically diverse proteins can give rise to amyloid fibrils; however, they are all accompanied by P component and glucosaminoglycans. With antibodies specific to apolipoprotein E (apo E) we used immunohistochemical techniques to test for the presence of this protein in both cerebral and systemic amyloid. We f...

journal_title：Neuroscience letters

authors： Wisniewski T,Frangione B

更新日期：1992-02-03 00:00:00

abstract：:Mutations in the glucocerebrosidase (GCase) gene (GBA) and GCase deficiency are major risk factors for Lewy body diseases. Decreased GCase activity enhances alpha-synuclein aggregation and disease development. Lysosomal integral membrane protein type 2, encoded by SCARB2, binds GCase targeting it to lysosomes and tran...

journal_title：Neuroscience letters

authors： Pérez-Roca L,Prada-Dacasa P,Segú-Vergés C,Gámez-Valero A,Serrano-Muñoz MA,Santos C,Beyer K

更新日期：2019-07-27 00:00:00

abstract：:We studied the extracellular concentration of glutamate and taurine in the frontal cortex of freely-moving pentylenetetrazole (PTZ) kindled rats using an in vivo microdialysis. A significant and sustained increase in the glutamate level was observed in the kindled rats, in contrast, a slight and delayed increase was o...

journal_title：Neuroscience letters

authors： Li Z,Yamamoto Y,Morimoto T,Ono J,Okada S,Yamatodani A

更新日期：2000-03-17 00:00:00

abstract：:By the use of the peroxidase--antiperoxidase (PAP) technique in the sinus node of several mammalian species, vasoactive intestinal polypeptide (VIP), neurotensin (NT) and substance P (SP) immunoreactive structures were detected. VIP and NT as well as SP immunoreactive fibers were found in close association to the vasc...

journal_title：Neuroscience letters

authors： Weihe E,Reinecke M

更新日期：1981-11-04 00:00:00

abstract：BACKROUND:A relatively small number of genetic variants are implicated to pathophysiology of intracerebral hemorrhage (ICH). Aquaporin-4 (AQP4) has been reported to be implicated in the pathophysiological processes of ICH development. OBJECTIVE:To examine the role of AQP4 gene region polymorphisms on the ICH risk. ME...

journal_title：Neuroscience letters

authors： Dardiotis E,Siokas V,Marogianni C,Aloizou AM,Sokratous M,Paterakis K,Dardioti M,Grigoriadis S,Brotis A,Kapsalaki E,Fountas K,Jagiella J,Hadjigeorgiou GM

更新日期：2019-03-23 00:00:00

abstract：:The soluble fraction of rat brain cortex yielded an antioxidant factor that inhibits the autoxidation of ascorbic acid at physiological pH. The measurements were based on spectrophotometric detection of ascorbic acid at 265 nm in a physiological salt solution of the Krebs-Ringer type, pH 7.4, or in sodium phosphate bu...

journal_title：Neuroscience letters

authors： Kovachich GB,Mishra OP

更新日期：1982-12-23 00:00:00

abstract：:We have compared changes in mRNA of three genes, zif268, raf B, and syntaxin 1 B, following the unilateral induction of long-term potentiation (LTP) in rats previously trained in a water maze, and in behaviourally naive animals. mRNA of all three genes was enhanced in the potentiated dentate gyrus of naive animals 3 h...

journal_title：Neuroscience letters

authors： Richter-Levin G,Thomas KL,Hunt SP,Bliss TV

更新日期：1998-07-17 00:00:00

abstract：:The aim of the present study is to investigate the mechanisms of suppression of splenic natural killer (NK) cytotoxicity caused by cold stress, using 6-hydroxydopamine (6-OHDA) as chemical sympathectomy. The NK activity was measured by (51)chromium release assay. Central sympathectomy with intracerebroventricular inje...

journal_title：Neuroscience letters

authors： Jiang XH,Guo SY,Xu S,Yin QZ,Ohshita Y,Naitoh M,Horibe Y,Hisamitsu T

更新日期：2004-03-18 00:00:00

abstract：:In the rat, electrical stimulation of the cranial end of the cut hepatic branch of the vagus nerve modulated gastric contractions. When the gastric contraction rate reached approximately one per min, nerve stimulation caused total suppression. When the stomach was free of contraction, nerve stimulation initiated one. ...

journal_title：Neuroscience letters

authors： Lee KC

更新日期：1985-01-07 00:00:00

abstract：:Dopamine (DA) neurons in the ventral tegmental area and substantia nigra pars compacta were induced to fire in bursts with application of N-methyl-D-aspartate (NMDA, 20 microM) and apamin (100 nM) while recording intracellularly in the rat brain slice. L-Arginine (300 microM), a substrate for nitric oxide (NO) product...

journal_title：Neuroscience letters

authors： Cox BA,Johnson SW

更新日期：1998-10-23 00:00:00