Protein kinase G increases AMPA receptor GluR1 phosphorylation at serine 845 after repeated cocaine administration in the rat nucleus accumbens.

abstract：:Classical theories on absence epilepsy suggest that spike-wave discharge (SWDs) represent thalamo-cortical oscillations, where an abnormally excitable cortex interacts with thalamus and brain stem reticular formation. The limbic system is generally not included in any theory about the pathogenesis of absence seizures....

journal_title：Neuroscience letters

authors： Tolmacheva EA,van Luijtelaar G

更新日期：2007-04-06 00:00:00

abstract：:An increase in diaphragmatic electromyogram (EMG) recorded via oesophageal electrodes during positive pressure breathing has been reported to indicate an increase in the neural outflow to the muscle. However, using similar techniques, the size of compound muscle action potentials produced by supramaximal phrenic nerve...

journal_title：Neuroscience letters

authors： McKenzie DK,Gandevia SC

更新日期：1986-09-25 00:00:00

abstract：:Neurotrophic factors regulate neuronal survival and differentiation and control neurite outgrowth by binding to tyrosine kinase receptors, the Trks, and a tumor necrosis factor (TNF) receptor-like molecule, p75 neurotrophin receptor. A proinflammatory cytokine, TNF, also affects survival and apoptotic death in neurona...

journal_title：Neuroscience letters

authors： Furuno T,Nakanishi M

更新日期：2006-01-16 00:00:00

abstract：:The intergeniculate leaflet (IGL) of the lateral geniculate complex is marked by the presence of neuro-peptide Y-containing neurons that project to the suprachiasmatic nuclei (SCN) of the hypothalamus. In the present study, we demonstrate that both the IGL and SCN in the hamster and rat are specifically delineated by ...

journal_title：Neuroscience letters

authors： Morin LP,Johnson RF,Moore RY

更新日期：1989-04-24 00:00:00

abstract：:Thermogenetics is a promising innovative neurostimulation technique, which enables robust activation of single neurons using thermosensitive cation channels and IR stimulation. The main advantage of IR stimulation compared to conventional visible light optogenetics is the depth of penetration (up to millimeters). Due ...

journal_title：Neuroscience letters

authors： Roshchin M,Ermakova YG,Lanin AA,Chebotarev AS,Kelmanson IV,Balaban PM,Zheltikov AM,Belousov VV,Nikitin ES

更新日期：2018-11-20 00:00:00

abstract：:Evidence indicates that sympathetic nerves and substance P (SP) are involved in some physiological and pathophysiological changes and activities in retina. The aim of this study was to investigate whether SP participates in the stress reaction and possible involvement of adrenergic mechanisms in modulation of the chan...

journal_title：Neuroscience letters

authors： Yang JH,Meng XX,Xie LS,Guo Z

更新日期：2008-10-10 00:00:00

abstract：:Very recent studies in adult gerbils and rats have shown that exposure to sublethal ischemia can confer neuroprotection from subsequent lethal ischemic episodes. To determine if a similar phenomenon can be elicited during the perinatal period, we have developed a preconditioning regimen that involves exposure to normo...

journal_title：Neuroscience letters

authors： Gidday JM,Fitzgibbons JC,Shah AR,Park TS

更新日期：1994-02-28 00:00:00

abstract：:beta-Amyloid protein immunoreactivity in neocortex and hippocampus of Alzheimer's disease and control brains has been measured using an automatic image analysis system. Successive fields from the pial surface to white matter in 4 neocortical sites, parahippocampal gyrus and along the pyramidal cell layer in the hippoc...

journal_title：Neuroscience letters

authors： Cairns NJ,Chadwick A,Luthert PJ,Lantos PL

更新日期：1991-08-05 00:00:00

abstract：:Multiple sclerosis is a currently incurable inflammatory demyelinating syndrome. Recent reports suggest that bone marrow derived mesenchymal stem cells may have therapeutic potential in experimental models of demyelinating disease, but various alternative mechanisms, ranging from systemic immune effects to local cell ...

journal_title：Neuroscience letters

authors： Gordon D,Pavlovska G,Glover CP,Uney JB,Wraith D,Scolding NJ

更新日期：2008-12-19 00:00:00

abstract：:We combined fluorescent tracing with immunohistochemistry to examine nitric oxide synthase (NOS) containing neurons in the rat ventral lateral geniculate nucleus (vLGN). NOS immunopositive neurons in vLGN had a similar appearance to previously described NADPH-d positive neurons. The majority (96%) of the NOS immunopos...

journal_title：Neuroscience letters

authors： Meng XW,Ohara PT,Ralston HJ 3rd

更新日期：1998-11-06 00:00:00

abstract：:We have found an APOE epsilon 4 allelic frequency of 0.289 (95% CI 0.195-0.383) in Spanish AD patients (n = 88; average age = 71.2 +/- 9.37) and of 0.061 (95% CI 0.023-0.099) in age-matched controls (n = 147; average age = 71.5 +/- 10.29). Remarkably no ApoE 4/4 subjects were observed in any of the age-matched control...

journal_title：Neuroscience letters

authors： Adroer R,Santacruz P,Blesa R,López-Pousa S,Ascaso C,Oliva R

更新日期：1995-04-21 00:00:00

abstract：:Due to the hypothetical role of ovarian hormones, estrogen and progesterone, in cocaine-induced behavioral activity and self-administration, this study investigated the effects of cocaine, estrogen, and progesterone administration on monoamine levels in the medial prefrontal cortex of ovariectomized hormone-treated ra...

journal_title：Neuroscience letters

authors： Perrotti LI,Beck KD,Luine VN,Quiñones V

更新日期：2000-09-22 00:00:00

abstract：:It remains unknown if tissue acidosis contributes to neuronal loss during cerebral ischemia. We report that brief intracellular acidification (pH 6.62) results in delayed neuronal loss in cultured hippocampal slices. Cell loss was located primarily in stratum pyramidale and the hilus suggesting that neurons were prefe...

journal_title：Neuroscience letters

authors： Shen H,Chan J,Kass IS,Bergold PJ

更新日期：1995-02-09 00:00:00

abstract：:Noradrenaline in the central nervous system plays an important role in regulating physiological functions, and is a key mechanistic component of general anesthesia. The purpose of this present study was to determine if nitrous oxide and xenon modulate noradrenaline release in the cerebral cortex. We performed a series...

journal_title：Neuroscience letters

authors： Yoshida H,Kushikata T,Tose R,Kudo M,Kudo T,Hirota K

更新日期：2010-01-22 00:00:00

abstract：:Interleukin-1 (IL-1) mediates numerous responses on the mouse anterior pituitary cell line AtT-20. We have studied the ligand binding properties of the IL-1 receptors (IL-1R) of the AtT-20 cells and found that they possess 1.5 x 10(3) receptors/cell with a Kd of 0.15 nM for [125I]IL-1 alpha. Using oligonucleotide prim...

journal_title：Neuroscience letters

authors： Bristulf J,Simoncsits A,Bartfai T

更新日期：1991-07-22 00:00:00

abstract：:Recent neuroimaging studies indicate that there may be common ground for esthetic and moral judgments. However, because previous studies focused on either esthetic or moral judgments and did not compare the two directly, the issue remains open whether a common ground actually exists. We employed functional magnetic re...

journal_title：Neuroscience letters

authors： Avram M,Gutyrchik E,Bao Y,Pöppel E,Reiser M,Blautzik J

更新日期：2013-02-08 00:00:00

abstract：:Phosphoramidon (100-350 micrograms i.c.v.), a selective enkephalinase inhibitor, induced in the rat a decrease of nociception to pressure stimulation without evident respiratory depression. In addition, intensive behavioural changes such as grooming (licking the fur, face washing and scratching), mounting behaviour an...

journal_title：Neuroscience letters

authors： Rupreht J,Ukponmwan OE,Admiraal PV,Dzoljic MR

更新日期：1983-11-11 00:00:00

abstract：:The expression of dystrophin-protein 71 (Dp71) was investigated during nerve growth factor (NGF) induced differentiation of PC12 cells. A semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) assay was designed to measure Dp71 mRNA, whereas the Dp71 protein amount was evaluated by immunoblot analy...

journal_title：Neuroscience letters

authors： Cisneros B,Rendon A,Genty V,Aranda G,Marquez F,Mornet D,Montañez C

更新日期：1996-08-02 00:00:00

abstract：:Pain threshold and pain tolerance of heat noxious stimuli were assessed to determine whether they are equivalent when measured at three equidistant sites of both volar forearms. Heat pain threshold and tolerance were measured in 18 healthy volunteers using a standard stimulation device consisting of a thermode. Pain t...

journal_title：Neuroscience letters

authors： Schaffner N,Wittwer A,Kut E,Folkers G,Benninger DH,Candia V

更新日期：2008-08-08 00:00:00

abstract：:Seizures are relatively common in the first weeks of life and can have lasting effects on brain development due to glutamate excitotoxicity. The excitatory amino acid transporter 2 (EAAT2) is responsible for the majority of glutamate uptake in the brain and mice with this gene deleted die from seizures. Therefore, we ...

journal_title：Neuroscience letters

authors： Lauriat TL,Schmeidler J,McInnes LA

更新日期：2007-01-22 00:00:00

abstract：:Thymol, which is contained in thyme essential oil, has various actions including antinociception and nerve conduction inhibition. Although thymol activates transient receptor potential (TRP) channels expressed in heterologous cells, it remains to be examined whether this is so in native neurons. It has not yet been ex...

journal_title：Neuroscience letters

authors： Xu ZH,Wang C,Fujita T,Jiang CY,Kumamoto E

更新日期：2015-10-08 00:00:00

abstract：:TRPA1 agonists cinnamaldehyde (CA) and mustard oil (allyl isothiocyanate=AITC) induce heat hyperalgesia and mechanical allodynia in human skin, and sensitize responses of spinal and trigeminal dorsal horn neurons to noxious skin heating in rats. TRPA1 is also implicated in cold nociception. We presently used behaviora...

journal_title：Neuroscience letters

authors： Tsagareli MG,Tsiklauri N,Zanotto KL,Carstens MI,Klein AH,Sawyer CM,Gurtskaia G,Abzianidze E,Carstens E

更新日期：2010-04-12 00:00:00

abstract：:The effects of suppression of postsynaptic density protein 95 (PSD-95) expression on the increased tyrosine phosphorylation of N-methyl-D-aspartate receptor subunit NR2A and interactions of Src and Fyn with NR2A after brain ischemia were investigated by immunoprecipitation and immunoblotting. Transient (15 min) brain ...

journal_title：Neuroscience letters

authors： Hou XY,Zhang GY,Zong YY

更新日期：2003-06-05 00:00:00

abstract：:Viral infections are frequently found in opioid addicts, subjecting them to immune challenge. However, the effects of immune challenge on opioid withdrawal are not fully understood. In the present study, mice were intraperitoneally injected with 2mg/kg polyinosinic-polycytidylic acid (Poly I:C, a viral mimetic) for 3 ...

journal_title：Neuroscience letters

authors： Chen L,Zhai H,Lu L,Chen S,Ning Y,Wang W

更新日期：2011-01-10 00:00:00

abstract：:Repeated stimulation can lead to a decrement in the amplitude of a response, or its disappearance. This is known as habituation. Responses recorded in the reticular formation of the brain to peripherally applied stimuli tend to habituate. Decerebration considerably reduces the occurrence of this habituation and naloxo...

journal_title：Neuroscience letters

authors： Boxer MI

更新日期：1983-09-19 00:00:00

abstract：:Novel retinal pigment epithelial cell gene (Norpeg, Rai14), a developmentally regulated mouse gene, encodes a protein containing six ankyrin repeats and a coiled-coil domain. The objective of the present study was to characterize the Norpeg protein and to analyze its expression in mouse retina using an antibody prepar...

journal_title：Neuroscience letters

authors： Kutty RK,Samuel W,Chen S,Vijayasarathy C,Dun Y,Mysona B,Wiggert B,Smith SB

更新日期：2006-09-01 00:00:00

abstract：:Kynurenic acid (KYNA) is an antagonist of (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid (AMPA) and N-methyl-D-aspartate (NMDA) receptors and it blocks the glycine site of the NMDA receptor preferentially (IC50 = 7.9 microM). KYNA is produced endogenously by transamination of its precursor L-kynurenin...

journal_title：Neuroscience letters

authors： Scharfman HE,Hodgkins PS,Lee SC,Schwarcz R

更新日期：1999-10-22 00:00:00

abstract：:The modification of tuning properties in the cochlea has been studied by means of tuning curves from auditory nerve fibers in kittens of various ages. Comparison of tuning curves of three characteristic frequencies (CF) shows that the tuning of high CF units tends to approach adult values by the end of the second post...

journal_title：Neuroscience letters

authors： Romand R

更新日期：1983-03-14 00:00:00

abstract：:This study investigated differences in the neural time-course of cognitive conflict and emotional conflict control, using event-related potentials (ERPs). Although imaging studies have provided some evidence that distinct, dissociable neural systems underlie emotional and nonemotional conflict resolution, no ERP study...

journal_title：Neuroscience letters

authors： Xue S,Li Y,Kong X,He Q,Liu J,Qiu J

更新日期：2016-04-21 00:00:00

abstract：:Responses of single neurones to vibrissal stimulation and to the iontophoretically applied putative neurotransmitters, L-glutamate and L-aspartate, were recorded in the trigeminal nucleus caudalis of the rat. Vibrissal responses were unaffected by the specific N-methyl-D-aspartate receptor antagonist, D-alpha-aminoadi...

journal_title：Neuroscience letters

authors： Salt TE,Hill RG

更新日期：1981-03-10 00:00:00