Assignment of Alzheimer's presenilin-2 (PS-2) gene to 1q42.1 by fluorescence in situ hybridization.

abstract：:Using an animal model of temporal lobe epilepsy, the kainic acid lesioned rat hippocampus, we have evaluated the possibility of modulating glutamate N-methyl-D-aspartate (NMDA) receptor-dependent evoked epileptiform activity through the manipulation of NMDA receptor redox sites. Epileptiform activity was recorded extr...

journal_title：Neuroscience letters

authors： Quesada O,Hirsch J,Ben-Ari Y,Bernard C

更新日期：1996-07-19 00:00:00

abstract：:The involvement of ecto-protein kinase activity in activity-dependent long-term potentiation (LTP) was studied in CA1 neurons of guinea-pig hippocampal slices. Application of 5 microM K-252b, an ecto-protein kinase inhibitor, blocked LTP induced by a theta-burst stimulation (3 bursts composed of 5 pulses at 100 Hz wit...

journal_title：Neuroscience letters

authors： Fujii S,Ito K,Osada H,Hamaguchi T,Kuroda Y,Kato H

更新日期：1995-03-03 00:00:00

abstract：:This immunohistochemical study demonstrated the presence of S-100 protein (-like substance) in the nervous systems of some invertebrate animals. The immunoreactivity of S-100 protein was detected in some neurosecretory cells, but not in glial cells in the brains (cerebral ganglia) of silkworms, cockroaches and earthwo...

journal_title：Neuroscience letters

authors： Endo Y,Endo T

更新日期：1988-07-19 00:00:00

abstract：:Visual P300 responses were recorded by using checkerboard-type stimuli. (1) High amplitude P300-delta responses were visible even in single trial event-related potentials (ERPs). (2) The algorithm based on the 'delta response metric' provides an efficient selection criterion for evaluation of P300 single trials in ERP...

journal_title：Neuroscience letters

authors： Schürmann M,Başar-Eroglu C,Kolev V,Başar E

更新日期：1995-09-15 00:00:00

abstract：:Employing double anterograde axonal tracing in combination with intracortical microstimulation, we examined the distribution patterns of corticosubthalamic inputs from forelimb representations of the dorsal (PMd) and ventral (PMv) divisions of the premotor cortex in the macaque monkey. The inputs from the PMd and PMv ...

journal_title：Neuroscience letters

authors： Nambu A,Tokuno H,Inase M,Takada M

更新日期：1997-12-12 00:00:00

abstract：:In 8 subjects the spontaneous termination of sleep was determined after repetitive exposure to either bright or dim light, between 6.00 and 9.00 h, on 3 days preceding sleep assessment. Sleep duration was significantly shorter following bright light than following dim light. During sleep the time course of EEG energy ...

journal_title：Neuroscience letters

authors： Dijk DJ,Visscher CA,Bloem GM,Beersma DG,Daan S

更新日期：1987-01-14 00:00:00

abstract：:Both backward masking and transcranial magnetic stimulation (TMS) are capable of hindering perception of a visual target. To study the relationship between these two methods we applied TMS over the occipital pole in combination with the visual backward masking technique shine-through. The recently discovered weak shin...

journal_title：Neuroscience letters

authors： Kammer T,Scharnowski F,Herzog MH

更新日期：2003-06-12 00:00:00

abstract：:Somatostatin (SRIF) release from fetal rat cortical cells was stimulated by exposure to 10(-5) M N-methyl-D-aspartate (NMDA) (250 +/- 20% of basal at 96 h). A similar but much less potent effect was seen with kainate (KA) but not with quisqualate (Q) which inhibited SRIF release (KA 150 +/- 13%, Q 65 +/- 18% of basal ...

journal_title：Neuroscience letters

authors： Ham J,Rickards C,Scanlon M

更新日期：1991-08-19 00:00:00

abstract：:Convergence of cardiac and cutaneous afferents onto neurons in the dorsal horn of the spinal cord was demonstrated in the cat. Responses of neurons to cutaneous stimulation revealed that they were either nociceptive specific (NS) or wide dynamic range (WDR) neurons. NS neurons were located in lamina I and outer zone o...

journal_title：Neuroscience letters

authors： Takahashi M,Yokota T

更新日期：1983-08-08 00:00:00

abstract：:The present study investigated one of the characteristics of No-go-related brain activity during somatosensory Go/No-go paradigms, by manipulating the stimulus site and response hand. Somatosensory event-related potentials (ERPs) were recorded in ten right-handed subjects. Electrical stimulation was delivered to the s...

journal_title：Neuroscience letters

authors： Nakata H,Sakamoto K,Kakigi R

更新日期：2010-07-12 00:00:00

abstract：:Nitric oxide synthase-immunoreactivity (NOS-IR) was detected in strands of nerve fibers entering the rat superior cervical ganglia (SCG) and in nerve fibers forming a plexus beneath the capsule of adrenal glands. Within the SCG, varicose NOS-IR fibers encircled virtually all postganglionic neurons and small diameter c...

journal_title：Neuroscience letters

authors： Dun NJ,Dun SL,Wu SY,Förstermann U

更新日期：1993-08-06 00:00:00

abstract：:Orthodromic stimulation with frequencies from 1 to 30 Hz causes facilitation of extracellularly recorded population spikes and a decrease of extracellular Ca2+ concentration ( [Ca2+]o ) monitored with ion selective microelectrodes at the cell body layer of area CA1 of the hippocampal slice. Reducing the Ca2+ content o...

journal_title：Neuroscience letters

authors： Konnerth A,Heinemann U

更新日期：1983-12-11 00:00:00

abstract：:Despite extensive data addressing the regulation of the hypothalamo-pituitary-adrenal (HPA) axis in vertebrates, the neuroendocrine regulation of stress in birds remains incomplete. The paraventricular nucleus (PVN) contains the key neuropeptides, corticotropin releasing hormone (CRH) and arginine vasotocin (AVT), con...

journal_title：Neuroscience letters

authors： Nagarajan G,Kang SW,Kuenzel WJ

更新日期：2017-03-06 00:00:00

abstract：:Effective treatments to improve survivability following exposure to the nerve agent soman have been established and are currently available. Unfortunately, electrographic brain seizures, neuroinflammation and brain cell death are still a potential problem even with treatment. In the present study we have characterized...

journal_title：Neuroscience letters

authors： Williams AJ,Berti R,Yao C,Price RA,Velarde LC,Koplovitz I,Schultz SM,Tortella FC,Dave JR

更新日期：2003-10-09 00:00:00

abstract：:An abnormal distribution of phosphorylated neurofilaments is present in some human neurodegenerative disorders including Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis. This study reports the changes of phosphorylated neurofilaments observed in rat spinal cord after intrathecal injection o...

journal_title：Neuroscience letters

authors： Hugon J,Vallat JM

更新日期：1990-10-30 00:00:00

abstract：:This experiment was designed to simulate experimentally the specific parameters of geomagnetic activity that evoke epileptic seizures. The numbers of overt limbic seizures (rearing, paroxysmal forelimb clonus and falling) in a population of epileptic rats were recorded nightly for 65 successive days between 0200 and 0...

journal_title：Neuroscience letters

authors： Michon AL,Persinger MA

更新日期：1997-03-07 00:00:00

abstract：:To investigate the working mechanism of the conflict processing system, pairs of colored numbers were sequentially presented on a screen to subjects. They were asked to determine if the magnitude or the color of the two numbers was identical. Event-related potentials (ERPs) were recorded at the same time. A negative p...

journal_title：Neuroscience letters

authors： Wang H,Wang Y,Kong J,Cui L,Tian S

更新日期：2001-02-09 00:00:00

abstract：:We examined by immunohistochemistry the effect of salt loading on the expression of tyrosine hydroxylase (TH), aromatic L-amino acid decarboxylase (AADC), and GTP cyclohydrolase I (GCH) in Purkinje cells of the mouse cerebellum. In control mice, only a few Purkinje cells were positive for TH or AADC. No Purkinje cells...

journal_title：Neuroscience letters

authors： Sakai M,Fujii T,Karasawa N,Arai R,Nagatsu I

更新日期：1995-07-14 00:00:00

abstract：:N-Methyl-d-Aspartate receptors (NMDARs) are present in both pyramidal neurons and interneurons of the hippocampus. These receptors play a key role in the structural plasticity of excitatory neurons, but to date little is known about their influence on the remodeling of interneurons. Among hippocampal interneurons, the...

journal_title：Neuroscience letters

authors： Pérez-Rando M,Castillo-Gómez E,Bellés M,Carceller H,Nácher J

更新日期：2017-09-29 00:00:00

abstract：:Mutations in the glucocerebrosidase (GCase) gene (GBA) and GCase deficiency are major risk factors for Lewy body diseases. Decreased GCase activity enhances alpha-synuclein aggregation and disease development. Lysosomal integral membrane protein type 2, encoded by SCARB2, binds GCase targeting it to lysosomes and tran...

journal_title：Neuroscience letters

authors： Pérez-Roca L,Prada-Dacasa P,Segú-Vergés C,Gámez-Valero A,Serrano-Muñoz MA,Santos C,Beyer K

更新日期：2019-07-27 00:00:00

abstract：:The binding of the lectin soybean agglutinin (SBA) to the olfactory system of both the rat and mouse was investigated histochemically. SBA bound to fibers in the accessory olfactory nerve and to glomeruli in the accessory olfactory bulb. In addition, SBA binding sites were present in some, but not all, glomeruli in th...

journal_title：Neuroscience letters

authors： Key B,Giorgi PP

更新日期：1986-08-29 00:00:00

abstract：:Mirror neurons, which have now been found in the human and songbird as well as the macaque, respond to both the observation and the performance of the same action. It has been suggested that their matching response properties have evolved as an adaptation for action understanding; alternatively, these properties may a...

journal_title：Neuroscience letters

authors： Catmur C

更新日期：2013-04-12 00:00:00

abstract：:Typical histopathological findings of multiple system atrophy (MSA) have been observed in motor related cortices, in addition to the common areas of the striatum, substantia nigra, olivopontocerebellar pathways, the intermediolateral cell columns of the spinal cord, and the cerebellum. The purpose of this study is to ...

journal_title：Neuroscience letters

authors： You H,Wang J,Wang H,Zang YF,Zheng FL,Meng CL,Feng F

更新日期：2011-09-08 00:00:00

abstract：:Galectin-3 is a β-galactosidase-binding lectin which is important in cell proliferation and apoptotic regulation. Encephalomyocarditis virus (EMCV), which includes the Enterovirus genus, can cause not only acute myocarditis but also neuronal degeneration of central nervous system in various animals including mice. The...

journal_title：Neuroscience letters

authors： Kobayashi K,Niwa M,Hoshi M,Saito K,Hisamatsu K,Hatano Y,Tomita H,Miyazaki T,Hara A

更新日期：2015-04-10 00:00:00

abstract：:In mammals, methyl-CpG binding proteins play a significant role in the control of gene expression through their association with chromatin-remodeling complexes. Mutations in the gene coding for methyl-CpG-binding protein 2 (MECP2) cause Rett syndrome and have also been reported in a number of X-linked mental retardati...

journal_title：Neuroscience letters

authors： dos Santos JM,Abdalla CB,Campos M Jr,Santos-Rebouças CB,Pimentel MM

更新日期：2005-04-29 00:00:00

abstract：:Parkinson's disease (PD) is characterized by bradykinesia, resting tremor, rigidity and postural instability as well as early symptoms. Previous studies that evaluated the association between H1/H2 MAPT haplotype and PD were mostly conducted in European populations in which the H1 haplotype was a reported risk factor ...

journal_title：Neuroscience letters

authors： Miranda-Morales EG,Sandoval-Carrillo A,Castellanos-Juárez FX,Méndez-Hernández EM,La Llave-León O,Quiñones-Canales G,Ruano-Calderón LA,Arias-Carrión O,Salas-Pacheco JM

更新日期：2019-01-18 00:00:00

abstract：:The functional interaction in the spinal cord between substance P and excitatory amino acid agonists was investigated. Behavioural responses were scored in mice after intrathecal administration of excitatory amino acid agonists and substance P, given separately or in combination. A strong potentiation of the effect wa...

journal_title：Neuroscience letters

authors： Mjellem-Joly N,Lund A,Berge OG,Hole K

更新日期：1991-11-25 00:00:00

abstract：:Neurite outgrowth is elicited from whole explants or dissociated neurons of 8--10-day-old chick embryo sensory, dorsal root ganglia when cultured in the presence of a high speed supernatant fraction (105,000 g) from homogenates of chick or rat heart, liver or brain. The neurite promoting activity is not identical to m...

journal_title：Neuroscience letters

authors： Lindsay RM,Tarbit J

更新日期：1979-05-01 00:00:00

abstract：:The critical period for observing a developmentally regulated form of synaptic plasticity in the visual cortex of young rats normally ends at about postnatal day 30. This developmentally regulated form of in vitro long-term potentiation (LTP) can be reliably induced in layers II-III by aiming high frequency, theta bur...

journal_title：Neuroscience letters

authors： Shaffery JP,Lopez J,Bissette G,Roffwarg HP

更新日期：2006-01-02 00:00:00

abstract：:Hippocampal synaptic plasticity between Schaffer collaterals and CA1 pyramidal neurons can be induced by activation of N-methyl-d-aspartate receptors (NMDARs) or of metabotropic glutamate receptors (mGluRs). Inhibitory GABAergic interneurons in this region abundantly terminate on pyramidal neurons and may thus influen...

journal_title：Neuroscience letters

authors： Rohde M,Tokay T,Köhling R,Kirschstein T

更新日期：2009-12-18 00:00:00