Adenosine receptor activation suppresses tactile hypersensitivity and potentiates spinal cord stimulation in mononeuropathic rats.

abstract：:During neuromuscular development, the nerve induces the expression of acetylcholine receptor (AChR) epsilon-subunit gene selectively in synaptic myonuclei. Here we show that even after elimination of neural effects by denervation, synaptic expression of epsilon-subunit transcripts is maintained for > 4 months. In cont...

journal_title：Neuroscience letters

authors： Herczeg A,Jones G,Brenner HR

更新日期：1995-06-23 00:00:00

abstract：:In the caudal postcentral finger region near or in the anterior bank of the intraparietal sulcus of alert monkeys, we found neurons that were activated selectively by the contact of the hand to certain common objects such as bottle brushes, acrylic plates, parts of the stabilized monkey's chair, etc. All of these neur...

journal_title：Neuroscience letters

authors： Iwamura Y,Tanaka M,Hikosaka O,Sakamoto M

更新日期：1995-02-17 00:00:00

abstract：:The trembler mouse suffers from a dominantly inherited mutation of the peripheral myelin protein 22 (PMP22) gene which results in an abnormal myelination of its peripheral nervous system. The recent identification of two different PMP22 mRNA differing in their 5' non-translated region led us to monitor their respectiv...

journal_title：Neuroscience letters

authors： Garbay B,Boiron-Sargueil F,Cassagne C

更新日期：1995-10-06 00:00:00

abstract：:Methyl-CpG binding protein 2 (MECP2) is a chromosome-binding protein that regulates the development and maintenance of brain circuits. Altered function of the protein product of MECP2 plays an important role in the etiology of many neurodevelopmental disorders. Mutations involving a loss of function are implicated in ...

journal_title：Neuroscience letters

authors： Tropea D,Mortimer N,Bellini S,Molinos I,Sanfeliu A,Shovlin S,McAllister D,Gill M,Mitchell K,Corvin A

更新日期：2016-05-16 00:00:00

abstract：:We analyzed the participation of N-methyl-d-aspartate (NMDA) receptors in the neuronal damage caused by adult-onset hypothyroidism. Wistar rats were randomly assigned into four groups. The euthyroid group received tap water. The hypothyroid group received methimazole (60 mg/kg) in their drinking water to induce hypoth...

journal_title：Neuroscience letters

authors： Alva-Sánchez C,Becerril A,Anguiano B,Aceves C,Pacheco-Rosado J

更新日期：2009-04-10 00:00:00

abstract：:A remarkable candidate gene for late-onset Alzheimer's disease (AD) is 24-dehydrocholesterol reductase (DHCR24) gene that encodes seladin-1 (selective AD indicator), an enzyme that is involved in the cholesterol biosynthetic pathway, exerts neuroprotective and anti-apoptotic effects, and found to be down regulated in ...

journal_title：Neuroscience letters

authors： Fehér A,Juhász A,Pákáski M,Kálmán J,Janka Z

更新日期：2012-09-20 00:00:00

abstract：:Existing literature concerning the effect of experimentally-induced diabetes on pain thresholds in rodent models remains controversial. In this work, we describe a phenotypical switch from streptozotocin-induced pinprick hypoalgesia to hyperalgesia observed in the same laboratory, in the same strain of rats, obtained ...

journal_title：Neuroscience letters

authors： Yadlapalli JSK,Dogra N,Walbaum AW,Prather PL,Crooks PA,Dobretsov M

更新日期：2018-04-23 00:00:00

abstract：:In fetal and adult human brains, calbindin immunoreactivity (CB-ir) of neostriatal neuropil showed inhomogeneous pattern. A mosaic of CB-ir neuropil patches matching the acetylcholinesterase (AChE)-reactive patches and most of the encapsulated cell-dense islands was distributed in a lighter stained background matrix. ...

journal_title：Neuroscience letters

authors： Letinić K,Kostović I

更新日期：1996-12-20 00:00:00

abstract：:The Nef protein of human immunodeficiency virus type 1 (HIV-1) is abundantly expressed in HIV-1-infected astrocytes and shares amino acid sequence homology to alpha-scorpion toxins which bind to potassium channels. Here we report effects of recombinant Nef and alpha-scorpion toxins on membrane potassium transport in h...

journal_title：Neuroscience letters

authors： Kort JJ,Jalonen TO

更新日期：1998-07-17 00:00:00

abstract：:Tau in cerebrospinal fluid (CSF) has been proposed as a diagnostic marker for Alzheimer's disease (AD). This paper presents a new sensitive sandwich ELISA allowing quantitation of tau from 8 microl CSF/well. A human specific monoclonal tau antibody HT7 was used as a capture antibody and a mixture of polyclonal tau ant...

journal_title：Neuroscience letters

authors： Yamamori H,Khatoon S,Grundke-Iqbal I,Blennow K,Ewers M,Hampel H,Iqbal K

更新日期：2007-05-17 00:00:00

abstract：:In order to clarify the participation of substance P in the expression of opiate withdrawal, we have investigated the effects induced by the new selective neurokinin-1 antagonist RP 67580 on naloxone-induced morphine withdrawal syndrome in rats. Intracerebroventricular administration of RP 67580 elicited a decrease in...

journal_title：Neuroscience letters

authors： Maldonado R,Girdlestone D,Roques BP

更新日期：1993-06-25 00:00:00

abstract：:The distribution of mRNA coding for a pituitary thyrotropin releasing-hormone (TRH) receptor was examined on sections of spinal cord and lower brainstem of rat using in situ hybridization. Hybridization signals were observed over large neurons in the ventral horn in cervical, thoracic, and lumbar segments of spinal co...

journal_title：Neuroscience letters

authors： Wu W,Elde R,Wessendorf MW,Hökfelt T

更新日期：1992-08-17 00:00:00

abstract：:Electrical stimulation of the primary auditory cortex (AI) of the cat was found to evoke EPSPs, IPSPs or EPSP-IPSP sequences in colliculogeniculate (CG) neurons in the inferior colliculus (IC) which responded antidromically to stimulation of the medial geniculate nucleus. The CG neurons responding to the AI stimulatio...

journal_title：Neuroscience letters

authors： Mitani A,Shimokouchi M,Nomura S

更新日期：1983-12-02 00:00:00

abstract：:Antibodies directed against a glutamate transporter (GLT-1) purified from rat brain were applied to cryostat sections of rat and macaque monkey retinae. In the brain, GLT-1 expression is found mainly in astrocytes, and therefore it has been suggested that GLT-1 may be a glutamate transporter specific to glial cells. H...

journal_title：Neuroscience letters

authors： Rauen T,Kanner BI

更新日期：1994-03-14 00:00:00

abstract：:Familial Alzheimer's disease (AD) due to PSEN1 mutations provides an opportunity to examine AD biomarkers in persons in whom the diagnosis is certain. We describe a 55 year-old woman with clinically probable AD and a novel PSEN1 mutation who underwent genetic, clinical, biochemical and magnetic resonance and nuclear i...

journal_title：Neuroscience letters

authors： Ringman JM,Gylys KH,Medina LD,Fox M,Kepe V,Flores DL,Apostolova LG,Barrio JR,Small G,Silverman DH,Siu E,Cederbaum S,Hecimovic S,Malnar M,Chakraverty S,Goate AM,Bird TD,Leverenz JB

更新日期：2011-01-10 00:00:00

abstract：:Triazolam can shift the phase of circadian rhythms in hamsters recorded in constant light or dark. This effect is apparently mediated by physical activity stimulated by the drug. We examined whether triazolam can shift the phase of circadian rhythms in a diurnal primate, the squirrel monkey, that is sedated by triazol...

journal_title：Neuroscience letters

authors： Mistlberger RE,Houpt TA,Moore-Ede MC

更新日期：1991-03-11 00:00:00

abstract：:It is uncertain if the several brain areas in response to presemantic picture processing are functionally homogeneous. Subjects were asked to discriminate visual stimulus pairs and event-related potentials (ERPs) were recorded from the scalp. A line-drawing picture (S1) was followed by another stimulus (S2) 600 ms lat...

journal_title：Neuroscience letters

authors： Wang Y,Tang X,Kong J,Zhuang D,Li S

更新日期：1998-12-04 00:00:00

abstract：:Thyroid hormone metabolism was investigated in the frontal cortex and amygdala in groups of rats either 'behaviorally dependent' on ethanol or chronically exposed to ethanol, but not 'dependent'. The activities of the 5'II deiodinase isoenzyme, which catalyzes the deiodination of thyroxine (T4) to the active metabolit...

journal_title：Neuroscience letters

authors： Baumgartner A,Eravci M,Pinna G,Hiedra L,Prengel H,Brödel O,Meinhold H

更新日期：1997-05-09 00:00:00

abstract：:The present study examined effects of high altitude exposure, which leads to development of hypoxia, on epiplexus cells associated with the choroid plexus in adult rats. At 2-5 h following exposure, epiplexus cells expressing inducible nitric oxide synthase (iNOS) were commonly observed. Increased expression of comple...

journal_title：Neuroscience letters

authors： Wang D,Kaur C

更新日期：2000-05-19 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurological disease characterized by degeneration and death of motor neurons. Aberrant protein aggregation and oxidative stress are implicated in the etiology of ALS; thus preventing propagation of early aggregation events and oxidative damage could be an...

journal_title：Neuroscience letters

authors： Evans TM,Bhattacharya A,Shi Y,Qi W,Block TJ,Chaudhuri A,Chaudhuri AR,Hawker K,Van Remmen H

更新日期：2016-06-15 00:00:00

abstract：:To investigate the relationship between apolipoprotein E (APOE) polymorphisms and the severity of traumatic brain injury (TBI) in acute stage in the cohort of mainland Chinese patients. We prospectively identified admissions to the two neurosurgical departments for head injury. A total of 110 subjects with TBI (80 mal...

journal_title：Neuroscience letters

authors： Jiang Y,Sun X,Xia Y,Tang W,Cao Y,Gu Y

更新日期：2006-11-13 00:00:00

abstract：:The availability of choline during the prenatal period influences neural and cognitive development. Here we report that choline supplementation during a six-day gestational period protects against neurodegeneration in the posterior cingulate and retrosplenial cortices of adult female rats produced by systemic administ...

journal_title：Neuroscience letters

authors： Guo-Ross SX,Jones KH,Shetty AK,Wilson WA,Swartzwelder HS

更新日期：2003-05-01 00:00:00

abstract：:A retrograde tracer, Diamidino yellow, was injected into the hindlimb region of the supplementary motor area after intracortical microstimulation mapping in the Japanese monkey. As a result, a cluster of retrogradely labeled neurons was found in the caudal bank of the arcuate sulcus, which corresponds to the ventral p...

journal_title：Neuroscience letters

authors： Tokuno H,Inase M

更新日期：1994-04-25 00:00:00

abstract：:Administration of the cannabinoid CB1 receptor antagonist SR141716 (3-10 mg/kg i.p.) abolished neuropeptide Y-induced overeating and significantly reduced ethanol and sucrose intake in CB1 wild-type (+/+) mice. In CB1 receptor knockout (-/-) mice, neuropeptide Y totally lost its capacity to increase food consumption. ...

journal_title：Neuroscience letters

authors： Poncelet M,Maruani J,Calassi R,Soubrié P

更新日期：2003-06-12 00:00:00

abstract：:Children and adolescents with Autism Spectrum Disorder (ASD) are characterized by an impaired Theory of Mind (ToM). Recent evidence suggested that two aspects of ToM (cognitive ToM versus affective ToM) are differentially impaired in individuals with ASD. In this study, we examined the neural correlates of cognitive a...

journal_title：Neuroscience letters

authors： Kim E,Kyeong S,Cheon KA,Park B,Oh MK,Chun JW,Park HJ,Kim JJ,Song DH

更新日期：2016-05-16 00:00:00

abstract：:The epithelial membrane protein 1 (EMP1) plays a role in neuronal differentiation and neurite outgrowth, which are involved in the pathogenesis of major depressive disorder (MDD). We sought to determine whether the EMP1 gene is implicated in MDD. We determined the mRNA expression levels of the EMP1 gene in peripheral-...

journal_title：Neuroscience letters

authors： Nakataki M,Iga J,Numata S,Yoshimoto E,Kodera K,Watanabe SY,Song H,Ueno S,Ohmori T

更新日期：2011-02-04 00:00:00

abstract：:Alzheimer's disease is correlated with neuronal degeneration and loss of neuronal precursors in different parts of the brain. It has been found disturbance in the homeostasis neural stem cells (NSCs) can cause neurodegeneration. Morphine, an analgesic agent, can disrupt the dynamic and normal state of NSCs. However, m...

journal_title：Neuroscience letters

authors： Salarinasab S,Nourazarian A,Nikanfar M,Abdyazdani N,Kazemi M,Feizy N,Rahbarghazi R

更新日期：2017-11-01 00:00:00

abstract：:The present study compared performance and event-related brain potentials between dyslexic subjects and control subjects while they performed a spatial selective attention-shifting task. The subjects received a prestimulus cue on each trial, which indicated whether the subjects should attend to a position to the left ...

journal_title：Neuroscience letters

authors： Wijers AA,Been PH,Romkes KS

更新日期：2005-02-10 00:00:00

abstract：:In untreated patients with Parkinson's disease (PD), the total (free and conjugated) serotonin (5-HT) and dopamine (DA) concentrations in the cerebrospinal fluid decreased significantly. While the 5-HT concentration displayed a non-significant trend of negative correlation with the DA concentration in controls, it had...

journal_title：Neuroscience letters

authors： Tohgi H,Abe T,Takahashi S,Takahashi J,Hamato H

更新日期：1993-09-03 00:00:00

abstract：:Five monkeys vocalizing at self-pace (self-paced vocalization) were well trained to vocalize in response to a monkey call (audio-initiated vocalization). Field potentials associated with audio-initiated vocalizations were recorded by using electrodes which were implanted chronically on the surface and at a 2.0-3.0 mm ...

journal_title：Neuroscience letters

authors： Gemba H,Kyuhou S,Matsuzaki R,Amino Y

更新日期：1999-09-03 00:00:00