Abstract：
:Thyroid hormone metabolism was investigated in the frontal cortex and amygdala in groups of rats either 'behaviorally dependent' on ethanol or chronically exposed to ethanol, but not 'dependent'. The activities of the 5'II deiodinase isoenzyme, which catalyzes the deiodination of thyroxine (T4) to the active metabolite triiodothyronine (T3), was elevated in the frontal cortex in both the 'behaviorally dependent' and the 'non-dependent' rats. The activities of the 5-II deiodinase isoenzyme, which catalyzes the inactivation of T3 to 3,3'-T2 was, however, selectively inhibited in the amygdalas of the rats 'behaviorally dependent' on ethanol, but normal in the 'non-dependent' rats. This suggests that increases in intracellular concentrations of T3 in the amygdala may be specifically related to reward mechanisms and the development of 'behavioral dependence' on ethanol.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Baumgartner A,Eravci M,Pinna G,Hiedra L,Prengel H,Brödel O,Meinhold Hdoi
10.1016/s0304-3940(97)00290-5subject
Has Abstractpub_date
1997-05-09 00:00:00pages
25-8issue
1eissn
0304-3940issn
1872-7972pii
S0304-3940(97)00290-5journal_volume
227pub_type
杂志文章abstract：:Life choice (e.g. occupation choice) often includes situations with two or more possible answers. How does the brain respond to such conflict-ridden situations? We investigated whether the dorsal anterior cingulate cortex (dACC) evaluates the degree of conflict between possible answers. Additionally, we investigated w...
journal_title：Neuroscience letters
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doi：10.1016/j.neulet.2009.04.056
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pub_type： 杂志文章
doi：10.1016/j.neulet.2007.01.038
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(98)00428-5
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journal_title：Neuroscience letters
pub_type： 杂志文章
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journal_title：Neuroscience letters
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pub_type： 杂志文章
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journal_title：Neuroscience letters
pub_type： 杂志文章
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
pub_type： 杂志文章
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journal_title：Neuroscience letters
pub_type： 杂志文章
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
pub_type： 杂志文章
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2004.07.004
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(93)90439-r
更新日期：1993-06-25 00:00:00
