Localization of the glutamate transporter GLT-1 in rat and macaque monkey retinae.

Abstract:

:Antibodies directed against a glutamate transporter (GLT-1) purified from rat brain were applied to cryostat sections of rat and macaque monkey retinae. In the brain, GLT-1 expression is found mainly in astrocytes, and therefore it has been suggested that GLT-1 may be a glutamate transporter specific to glial cells. However, in the rat retina, cones and two distinct cone bipolar cell types were strongly immunoreactive. In the monkey retina, flat midget bipolars and one diffuse bipolar cell type (DB2)), were found to be labelled. Müller cells or astrocytes, the neuroglial cells of rat and monkey retinae, were not GLT-1-immunoreactive.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Rauen T,Kanner BI

doi

10.1016/0304-3940(94)90375-1

subject

Has Abstract

pub_date

1994-03-14 00:00:00

pages

137-40

issue

1-2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(94)90375-1

journal_volume

169

pub_type

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