Fronto-parieto-cerebellar interaction associated with intermanual transfer of monkey tool-use learning.

Abstract:

:Prior motor skill learning (original learning; OL) with one hand (original hand; OH) can affect relearning of the same skill (transfer learning; TL) with the opposite hand (transferred hand; TH). This phenomenon is known as intermanual transfer of learning. We explored specialization of brain activation underlying tool-use between hands by measuring regional cerebral blood flow in two monkeys using positron emission tomography. We found brain activation specified for TL in the bilateral prefrontal cortex, bilateral intraparietal sulcus region, and cerebellum contralateral to TH. The results suggest that those regions may be related to intermanual transfer of tool-use learning, presumably in terms of modifying a motor engram specific for OH.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Obayashi S,Suhara T,Kawabe K,Okauchi T,Maeda J,Nagai Y,Iriki A

doi

10.1016/s0304-3940(02)01477-5

keywords:

subject

Has Abstract

pub_date

2003-03-20 00:00:00

pages

123-6

issue

2

eissn

0304-3940

issn

1872-7972

pii

S0304394002014775

journal_volume

339

pub_type

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