Abstract：
:The availability of choline during the prenatal period influences neural and cognitive development. Here we report that choline supplementation during a six-day gestational period protects against neurodegeneration in the posterior cingulate and retrosplenial cortices of adult female rats produced by systemic administration of the N-methyl-D-aspartate receptor antagonist dizocilpine (MK-801). These data show that availability of choline during a brief prenatal period diminishes vulnerability to neurotoxicity in adult offspring.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Guo-Ross SX,Jones KH,Shetty AK,Wilson WA,Swartzwelder HSdoi
10.1016/s0304-3940(03)00119-8keywords:
subject
Has Abstractpub_date
2003-05-01 00:00:00pages
161-3issue
2eissn
0304-3940issn
1872-7972pii
S0304394003001198journal_volume
341pub_type
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journal_title：Neuroscience letters
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pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/0304-3940(96)12702-6
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abstract：:The volume density of mast cells was estimated in nerve end neuromas at various time-points after transection of the left sciatic nerve of 6-week-old mice. After an initial reduction in the amount of mast cells there was a steady increase with numerous cells in 6-month-old neuromas. The variation in amount of mast cel...
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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doi：10.1016/j.neulet.2007.04.066
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2013.07.008
更新日期：2013-08-29 00:00:00
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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