Abstract:
:The perikarya of the dopaminergic and non-dopaminergic neurons contained in the substantia nigra were selectively destroyed by a proper, local injection of 6-hydroxydopamine or kainic acid, respectively. Both lesions resulted in a marked decrease of the nigral GABA-binding sites. The effect of 6-hydroxydopamine was restricted to the high affinity receptors, while kainic acid specifically decreased the low affinity ones.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
De Montis GM,Olianas MC,Mulas G,Lloyd KG,Tagliamonte Adoi
10.1016/0304-3940(81)90007-0subject
Has Abstractpub_date
1981-05-29 00:00:00pages
257-61issue
3eissn
0304-3940issn
1872-7972pii
0304-3940(81)90007-0journal_volume
23pub_type
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