The decline in serum choline concentration in humans during and after surgery is associated with the elevation of cortisol, adrenocorticotropic hormone, prolactin and beta-endorphin concentrations.

Abstract:

:Serum choline concentrations decrease during and after surgery. We undertook this study to determine whether the decrease of choline is associated with an increase in stress hormones. In 16 patients undergoing abdominal surgery with general anesthesia, circulating choline cortisol, prolactin, adrenocorticotropic hormone (ACTH) and -endorphin levels were measured before, during and after surgery. Choline levels decreased by 41% (P<0.01) during surgery, remained 15-38% decreased for 48 h, and returned to preoperative values 72 h after surgery. The decrease in serum choline was associated and inversely correlated with the increase in serum cortisol (P<0.001; r = -0.642), prolactin (P<0.001; r = -0.756), -endorphin (P<0.001; r = -0.726) and ACTH (P<0.01; r = -0.458). In conclusion, we found that abdominal surgery induces a decline in serum choline associated with an increase in circulating cortisol, prolactin, ACTH and -endorphin.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Ozarda Ilçöl Y,Ozyurt G,Kilicturgay S,Uncu G,Ulus IH

doi

10.1016/s0304-3940(02)00171-4

keywords:

subject

Has Abstract

pub_date

2002-05-10 00:00:00

pages

41-4

issue

1

eissn

0304-3940

issn

1872-7972

pii

S0304394002001714

journal_volume

324

pub_type

杂志文章
  • Dihydropyridines modulate K+-evoked amino acid and adenosine release from cerebellar neuronal cultures.

    abstract::Partial depolarization of primary cerebellar neuronal cultures with K+ evoked the release of aspartate, glutamate, adenosine, serine, taurine, gamma-aminobutyric acid (GABA), alanine and proline. The dihydropyridine calcium channel agonist, BAY K 8644, significantly augmented the K+-induced release of adenosine, aspar...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90314-5

    authors: Philibert RA,Dutton GR

    更新日期:1989-07-17 00:00:00

  • Glutamate-induced calcium responses in rat primary cortical cultures are potentiated by co-administration of glutamate transport inhibitors.

    abstract::The effects of glutamate uptake inhibitors on the L-glutamate-induced increase in intracellular calcium concentrations were assessed in rat primary cortical cultures. The glutamate (10 microM)-induced rise in intracellular calcium concentrations was strongly and dose dependently increased and prolonged by simultaneous...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)11395-d

    authors: Freund WD,Grieshop B,Neumann U,Reddig S

    更新日期:1995-03-16 00:00:00

  • Kainic acid binding in human caudate nucleus: effect of Huntington's disease.

    abstract::Kainic acid binding was measured in crude membrane fractions prepared from postmortem human caudate tissue of control persons and patients afflicted with Huntington's disease. A significant reduction in binding sites with no change in affinity was found in the Huntington's tissue, the apparent dissociation constants (...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(79)96156-1

    authors: Henke H

    更新日期:1979-10-01 00:00:00

  • Acetyl-l-carnitine enhances myelination of regenerated fibers of the lateral olfactory tract.

    abstract::It is well known that acetyl-l-carnitine (ALC) has various neuroprotective effects against neurodegenerative diseases. In addition, it has been reported that ALC facilitates myelination of regenerated axons after peripheral nerve injuries. We previously reported that spontaneous regeneration of the lateral olfactory t...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2017.06.001

    authors: Fukushima N,Yokouchi K,Kuroiwa M,Kawagishi K,Moriizumi T

    更新日期:2017-07-13 00:00:00

  • Event-related alpha desynchronization in touch - Comparing attention and perception.

    abstract::An event-related decrease in alpha power contralateral to the presentation of a stimulus is now a well-established phenomenon. Two distinct accounts of the functional role of alpha changes are present in the literature that either focus on alpha changes observed during attentional or simple perceptual tasks. This stud...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2019.04.058

    authors: Silas J,Tipple A,Jones A

    更新日期:2019-07-13 00:00:00

  • Grip force control and hand dexterity are impaired in individuals with diabetic peripheral neuropathy.

    abstract::Diabetic peripheral neuropathy (DPN) affects the sensory function of the hands and, consequently, may negatively impact hand dexterity, maximum grip strength (GSMax), and hand grip force (GF) control during object manipulation. The aims of this study were to examine and compare the GF control during a simple holding t...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2017.08.071

    authors: Lima KCA,Borges LDS,Hatanaka E,Rolim LC,de Freitas PB

    更新日期:2017-10-17 00:00:00

  • Sciatic and femoral nerve sensory neurones occupy different regions of the L4 dorsal root ganglion in the adult rat.

    abstract::The topographical distribution of sciatic and femoral nerve sensory neuronal somata in the L4 dorsal root ganglion of the adult rat was mapped after retrograde tracing with one or two of the dyes Fast Blue, Fluoro-Gold, or Diamidino Yellow. The tracers were applied to the proximal transected end of either nerve alone,...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(98)00518-7

    authors: Puigdellívol-Sánchez A,Prats-Galino A,Ruano-Gil D,Molander C

    更新日期:1998-07-31 00:00:00

  • Stimulatory effects of the central amygdaloid nucleus on pancreatic exocrine secretion in rats.

    abstract::The effects of electrical stimulation of the central (CE) and basolateral (BL) amygdaloid nuclei on pancreatic exocrine secretion were tested in urethane-anesthetized rats. Electrical stimulation (0.1 mA, 1 ms, 40 Hz) of the CE significantly increased basal and hormone (secretin+cholecystokinin-8)-infused pancreatic e...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90352-2

    authors: Hahn SJ,Yoon SH,Sim SS,Rhie DJ,Jo YH,Kim MS

    更新日期:1994-03-14 00:00:00

  • Functional organization of the primary motor cortex characterized by event-related fMRI during movement preparation and execution.

    abstract::Neuronal recording and neuroimaging studies have shown that the primary motor area (M1) not only participates in motor execution, but is also engaged during movement preparation. The purpose of the present study was to map the distribution of the preparation- and execution-related activity within the contralateral M1 ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(02)01236-3

    authors: Zang Y,Jia F,Weng X,Li E,Cui S,Wang Y,Hazeltine E,Ivry R

    更新日期:2003-02-06 00:00:00

  • Two types of rhythm in the respiratory network output in the isolated ventrolateral medulla in the neonatal rats.

    abstract::Effects of substance P and extracellular [K(+)](o) on respiratory motor activity in the ventrolateral medulla in neonatal rat (0-4 days old) brainstem-spinal cord preparation were studied. In addition to fictive eupneic rhythm (8-13 bursts/minute), the respiratory motor output was composed of biphasic bursts which mig...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(03)00645-1

    authors: Shvarev YN,Lagercrantz H,Yamamoto Y

    更新日期:2003-08-14 00:00:00

  • Tonic facilitation of glutamate release by glycine binding sites on presynaptic NR2B-containing NMDA autoreceptors in the rat visual cortex.

    abstract::We have previously shown that glycine binding sites on presynaptic NMDA receptors (NMDA-Rs) can tonically regulate glutamate release in the rat visual cortex. In the present study, we investigated the subunit composition of these presynaptic NMDA-Rs. We recorded miniature a-amino-3-hydroxy-5-methyl-4-isoxazolepropioni...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2007.12.023

    authors: Li YH,Han TZ,Meng K

    更新日期:2008-02-27 00:00:00

  • Differential activity in the premotor cortex subdivisions in humans during mental calculation and verbal rehearsal tasks: a functional magnetic resonance imaging study.

    abstract::To investigate a possible role of the lateral premotor cortex in human cognitive processes, we compared brain activity during mental-operation numeral (MO-numeral) and verbal rehearsal (VR) tasks, using block-design functional MRI. Sixteen healthy subjects serially added a series of single-digit numbers during the MO-...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(03)00692-x

    authors: Hanakawa T,Honda M,Okada T,Fukuyama H,Shibasaki H

    更新日期:2003-08-28 00:00:00

  • NGP1-01, a lipophilic polycyclic cage amine, is neuroprotective in focal ischemia.

    abstract::NGP1-01, a member of the pentacycloundecylamine cage compound family, was recently shown to exhibit both NMDA receptor channel blocking and L-type calcium channel antagonism activity. In the present study, focal ischemia was induced in mice by permanent middle cerebral artery occlusion (MCAO) to test for potential neu...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2005.03.042

    authors: Mdzinarishvili A,Geldenhuys WJ,Abbruscato TJ,Bickel U,Klein J,Van der Schyf CJ

    更新日期:2005-07-22 00:00:00

  • Knockdown of FoxO3a induces increased neuronal apoptosis during embryonic development in zebrafish.

    abstract::Neuronal apoptosis sculpts the developing brain, and nearly all identified classes of neurons seem to be produced "in excess" during development. FoxO transcription factors regulate apoptosis in vitro in deprived of neurotrophins. It is unknown if FoxO3a is involved in the development of neurons. Here, we report a rol...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.07.068

    authors: Peng K,Li Y,Long L,Li D,Jia Q,Wang Y,Shen Q,Tang Y,Wen L,Kung HF,Peng Y

    更新日期:2010-10-29 00:00:00

  • Muscarinic cholinoreceptors (M1-, M2-, M3- and M4-type) modulate the acetylcholine secretion in the frog neuromuscular junction.

    abstract::Muscarinic cholinoreceptors regulate the neurosecretion process in vertebrate neuromuscular junctions. The diversity of muscarinic effects on acetylcholine (ACh) secretion may be attributed to the different muscarinic subtypes involved in this process. In the present study, the location of five muscarinic receptor sub...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2017.04.015

    authors: Tsentsevitsky AN,Kovyazina IV,Nurullin LF,Nikolsky EE

    更新日期:2017-05-10 00:00:00

  • Functional coupling of human right and left cortical motor areas demonstrated with partial coherence analysis.

    abstract::Although a linear correlation between oscillatory activities in the right and left motor cortices during movements has been shown in monkeys, there has been a debate whether scalp-recorded EEG coherence in human reflects a similar association. By applying partial coherence analysis, we demonstrated that interhemispher...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01165-4

    authors: Mima T,Matsuoka T,Hallett M

    更新日期:2000-06-23 00:00:00

  • Subcellular localization of increased incorporation of [3H]fucose following passive avoidance learning in the chick.

    abstract::The effect of training on a passive avoidance test on incorporation of [3H]fucose into subcellular fractions of the anterior forebrain roof of 1-day-old chicks was determined. Isotope was injected intraperitoneally, and birds tested and killed after 3 h. There was an increase in incorporation in trained compared with ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(80)90285-2

    authors: Burgoyne RD,Rose SP

    更新日期:1980-10-02 00:00:00

  • Morphology of somatosensory evoked fields: inter-hemispheric similarity as a parameter for physiological and pathological neural connectivity.

    abstract::The morphology of somatosensory evoked fields (SEF) following electrical separate stimulation of left and right median nerve in 22 healthy volunteers was explored. The analysis of morphological properties of individual SEFs has been performed, in order to quantify an inter-hemispheric correlation coefficient. Despite ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01171-x

    authors: Tecchio F,Pasqualetti P,Pizzella V,Romani G,Rossini PM

    更新日期:2000-06-30 00:00:00

  • Non-independent quantum bumps in Limulus ventral nerve photoreceptors--a new insight in the light transduction mechanism.

    abstract::Single photon-induced transient currents, called quantum bumps were stimulated by short flashes in dark-adapted ventral nerve photoreceptors of Limulus. Flash intensities were set to activate 3 or more bumps. In most cases, current bumps were activated with a constant rate. The frequency of bump occurrence was between...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90725-m

    authors: Nagy K

    更新日期:1992-09-14 00:00:00

  • Binary expression of olfactory bulb-protein tyrosine phosphatase in rat central nervous system: developmental gene regulation in neonate cerebral cortex and constitutive expression in olfactory-rhinencephalon.

    abstract::Olfactory bulb-protein tyrosine phosphatase (OB-PTP) is a receptor type PTPase dominantly expressed in olfactory bulb. Previously, we isolated and molecularly cloned a rat OB-PTP cDNA from an embryonal brain cDNA library. In the present study, we investigated its temporal and spatial gene expression by Northern blot a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(96)12738-5

    authors: Yahagi Y,Tagawa M,Tomoda T,Shirasawa T

    更新日期:1996-06-21 00:00:00

  • Characteristics and classification of hippocampal θ rhythm induced by passive translational displacement.

    abstract::Theta rhythms in the hippocampus are believed to be the "metric" relating to various behavior patterns for free roaming rats. In this study, the theta rhythms were studied while rats either walked or were passively translated by a toy car on a linear track (referred to as WALK and TRANS respectively). For the similar ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.03.005

    authors: Xie K,Yan Y,Fang X,Gao S,Hong B

    更新日期:2012-04-25 00:00:00

  • Insulin-like growth factor 1 inhibits glucocorticoid-induced glutamine synthetase activity in cultured L6 rat skeletal muscle cells.

    abstract::We previously demonstrated the preventive effect of insulin-like growth factor 1 (IGF-1) on steroid myopathy in rats. However, the mechanism by which IGF-1 inhibits steroid myopathy remains unclear. Recent studies have revealed that glutamine synthetase (GS) is induced by glucocorticoid and may be related to the devel...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)01667-6

    authors: Kimura K,Kanda F,Okuda S,Chihara K

    更新日期:2001-04-20 00:00:00

  • Remacemide hydrochloride reduces cortical lesion volume following brain trauma in the rat.

    abstract::We evaluated the therapeutic effects of remacemide hydrochloride, an N-methyl-D-aspartate (NMDA) receptor-associated ionophore blocker with sodium channel blocking activity, on cortical lesion volume and memory dysfunction following parasagittal fluid-percussion brain injury in the anesthetized rat. We found that intr...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)00551-x

    authors: Smith DH,Perri BR,Raghupathi R,Saatman KE,McIntosh TK

    更新日期:1997-08-15 00:00:00

  • Effects of central leptin administration on blood pressure in normotensive rats.

    abstract::We tested the hypothesis that intracerebroventricular (i.c.v.) administration of leptin would increase mean arterial pressure (MAP) in ad libitum (AL) fed and food deprived (FD) normotensive rats. Male Sprague-Dawley rats were chronically instrumented with a guide cannula directed at the lateral ventricle and a caroti...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(98)00223-7

    authors: Casto RM,VanNess JM,Overton JM

    更新日期:1998-04-17 00:00:00

  • Phenytoin suppresses spontaneous ectopic discharge in rat sciatic nerve neuromas.

    abstract::Afferent fibers ending in nerve-end neuromas generate spontaneous impulse discharge which has been implicated as a cause of paraesthesias and pain following peripheral nerve injury in man. We now show in rats that the anticonvulsant drug phenytoin (PT), applied systemically or topically onto desheathed neuromas, suppr...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(85)90339-8

    authors: Yaari Y,Devor M

    更新日期:1985-07-04 00:00:00

  • Differential effects of remacemide and desglycinyl-remacemide on epileptiform burst firing in the rat hippocampal slice.

    abstract::Remacemide is a potential anticonvulsant drug with an active metabolite, desglycinyl-remacemide (DGR). Both moieties have been reported to block neuronal Na(+) channels and the N-methyl-D-aspartate (NMDA) subtype of glutamate receptor. The effects of remacemide and DGR on zero Mg(2+)/4-aminopyridine-induced epileptifo...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)02511-3

    authors: Santangeli S,Sills GJ,Stone TW,Brodie MJ

    更新日期:2002-03-15 00:00:00

  • Stimulation by nerve growth factor of neuropeptide synthesis in the adult rat in vivo: bilateral response to unilateral intraplantar injections.

    abstract::Unilateral intraplantar injections (1/day for 3 days) of 4 mu g nerve growth factor (NGF) into the rat hindpaw increased the expression of prepro-tachykinin (PPT)- and prepro-calcitonin gene-related peptide (ppCGRP)-mRNA in bilateral L5 dorsal root ganglia (DRGs). This was accompanied by an increase of CGRP-like immun...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)12287-7

    authors: Amann R,Sirinathsinghji DJ,Donnerer J,Liebmann I,Schuligoi R

    更新日期:1996-01-26 00:00:00

  • Genetic analysis of lysosomal alpha-galactosidase A gene in sporadic Parkinson's disease.

    abstract::Parkinson's disease (PD) is a progressive neurodegenerative disease. Majority of PD cases are sporadic, resulting from interaction of genetic and environmental factors. Accumulating evidence indicates that autophagy, which delivers alpha-synuclein to lysosomes for degradation, is involved in the PD pathogenesis. Some ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2011.05.238

    authors: Wu G,Pang S,Feng X,Zhang A,Li J,Gu K,Huang J,Dong H,Yan B

    更新日期:2011-08-01 00:00:00

  • Neuroprotective and memory enhancing effects of auraptene in a rat model of vascular dementia: Experimental study and histopathological evaluation.

    abstract::Vascular dementia and Alzheimer disease are most common type of dementia. These diseases have been associated with cognitive decline and affected personal behavioral activities. Moreover, the pattern of cerebral blood flow in mild cognitive disorder has appeared as a predictive indication for the development into Alzh...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2016.04.047

    authors: Ghanbarabadi M,Iranshahi M,Amoueian S,Mehri S,Motamedshariaty VS,Mohajeri SA

    更新日期:2016-06-03 00:00:00

  • The mechanism of inhibition by xanthine of adenosine A1-receptor responses in rat hippocampus.

    abstract::We have recently observed that the free radical-generating mixture of xanthine and xanthine oxidase (X/XO) can suppress the inhibitory effects of adenosine on synaptic transmission in the hippocampus, but that this action can be mimicked by xanthine alone. We have now clarified the mechanism of these interactions by u...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.04.075

    authors: Shahraki A,Fukunari A,Stone TW

    更新日期:2004-07-29 00:00:00